SR One Capital Management, LP

CIK

1910264

Location

Redwood City, CA

Portfolio Value

Mid $1,039,007,697

Diversification

Diversified

Filing Date

Global Rank

#2,456 / 8,795 ▲ 379 · as of Jun 2026

Top Industry

Biotechnology 97.4%

3Y Alpha vs SPY

+14.8%

Period ended 3 months ago

Filed Aug 12, 2026 · 56d

19 quarters · since Dec 2021

Clone Performance

Build a hypothetical price-return history from this filer's public 13F holdings.

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Portfolio Concentration

15 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026

Top Position

28.4%

+4.9 pts

Top 5

71.0%

−2.5 pts

Top 10

95.1%

−2.6 pts

HHI

1,399

Diversified+58

Portfolio Trend

19 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2026

Sector	% Portfolio	Value	Positions
Healthcare	100.0%	$1,039,007,697	15

Last Quarter's Activity

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Jun 30, 2026 vs Mar 31, 2026

Added To

Positions the filer increased

1 positions

Ticker	Company	Δ Shares	Shares	Value	Open
ORIC	Oric Pharmaceuticals, Inc.	+100,455	4,615,384	$49,984,608
No positions match the current search.

Trimmed

Positions the filer reduced

No qualifying positions this quarter.

New Positions

Positions the filer opened this quarter

3 positions

Ticker	Company	Shares	Value
AVLN	Avalyn Pharma Inc.	3,308,649	$108,920,725
ODTX	Odyssey Therapeutics, Inc.	3,794,883	$71,002,260
MOBI	Mobia Medical, Inc.	1,986,072	$26,613,364
No positions match the current search.

Sold Out

Positions the filer fully exited

2 positions

Ticker	Company	Shares	Value
ORKA	Oruka Therapeutics, Inc.	430,330	$21,107,686
—		2,346,630	$0
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

15 tracked positions · $1,039,007,697 total · filing declares 15 positions · $1,039,007,705 · as of Jun 30, 2026

All sectors Healthcare

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	% of Portfolio
MANE	Veradermics, Inc Healthcare	Held	2,401,868	0	$295,285,651	+94.7%	28.42%
ZBIO	Zenas BioPharma, Inc. Healthcare	Held	5,037,854	0	$127,860,734	+29.8%	12.31%
CRSP	CRISPR Therapeutics AG Healthcare	Held	2,038,763	0	$111,194,134	+14.7%	10.70%
AVLN	Avalyn Pharma Inc. Healthcare	NEW	3,308,649	NEW	$108,920,725	NEW	10.48%
DSGN	Design Therapeutics, Inc. Healthcare	Held	6,526,476	0	$94,438,107	+36.0%	9.09%
ODTX	Odyssey Therapeutics, Inc. Healthcare	NEW	3,794,883	NEW	$71,002,260	NEW	6.83%
ALMS	Alumis Inc. Healthcare	Held	1,959,896	0	$55,151,473	+27.7%	5.31%
ORIC	Oric Pharmaceuticals, Inc. Healthcare	Added	4,615,384	+100,455	$49,984,608	−12.6%	4.81%
MLYS	Mineralys Therapeutics, Inc. Healthcare	Held	1,563,966	0	$42,195,802	−0.4%	4.06%
SPRY	ARS Pharmaceuticals, Inc. Healthcare	Held	4,012,903	0	$32,143,353	−0.2%	3.09%
MOBI	Mobia Medical, Inc. Healthcare	NEW	1,986,072	NEW	$26,613,364	NEW	2.56%
NKTX	Nkarta, Inc. Healthcare	Held	3,333,333	0	$9,433,332	+34.1%	0.91%
OCS	Oculis Holding AG Healthcare	Held	641,022	0	$8,890,975	−47.8%	0.86%
RARE	Ultragenyx Pharmaceutical Inc. Healthcare	Held	137,753	0	$4,599,572	+59.4%	0.44%
ENGN	enGene Therapeutics Inc. Healthcare	Held	747,750	0	$1,293,607	−74.6%	0.12%

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.