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Equibles

CRSP

CRISPR Therapeutics AG

Company with tickers: CRSP

CIK
1674416
CUSIP
H17182108
Shares Outstanding
98,484,128
13F Activity (30d)
156 filings 134 filers

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 447
Total Value: $1,715,146,296
Total Shares: 36,055,214
Showing 1–100 of 467 holdings by value · page 1 of 5

Institutional Ownership Trend

25 quarters

Holder Concentration

Across 447 13F filers · Δ vs Dec 31, 2025
Top Holder
16.9%
Jun 2023 → Mar 2026 · range 12.4% – 16.9%
+0.3 pts
Top 5
49.2%
Jun 2023 → Mar 2026 · range 36.7% – 49.4%
−0.3 pts
Top 10
69.1%
Jun 2023 → Mar 2026 · range 52.6% – 69.1%
+0.5 pts
HHI
663
Jun 2023 → Mar 2026 · range 440 – 663
Broadly held+4

Quarterly Activity

vs Dec 31, 2025
New
74
Increased
159
Decreased
99
Sold Out
75
Unchanged
115
Holder count: -1
Institutional value: -8.7%
Shares held: +0.7%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega TWO SIGMA INVESTMENTS, LP +1,012,430 1,483,051
Mega STATE STREET CORP +229,060 3,982,500
Large Orbis Allan Gray Ltd +155,866 6,106,011
Mega GEODE CAPITAL MANAGEMENT, LLC +127,941 2,377,164
Large KBC Group NV +113,997 116,847

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Large Squarepoint Ops LLC −529,233 173,675
Large Caption Management, LLC −493,600 57,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP −451,165 1,647,106
Mega D. E. Shaw & Co., Inc. −268,600 142,700
Small Neo Ivy Capital Management −77,001 1,725

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mid Amova Asset Management Americas, Inc. 1,853,875 $88,188,833
Mega VANGUARD CAPITAL MANAGEMENT LLC 1,142,543 $54,350,770
Mega VANGUARD FIDUCIARY TRUST CO 542,682 $25,815,382
Large ExodusPoint Capital Management, LP 135,129 $6,428,086
Large Trexquant Investment LP 127,181 $6,050,000

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega UBS Group AG 2,524,144 $132,366,109
Large LOOMIS SAYLES & CO L P 899,331 $47,160,916
Large TWO SIGMA ADVISERS, LP 162,400 $8,516,256
Mid Contrarius Group Holdings Ltd 156,605 $8,212,366
Mid No Street GP LP 125,000 $6,555,000
Filter: New 74 Increased 159 Reduced 99 Sold out 75 Unchanged 115
Showing 100 of 467
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Large Orbis Allan Gray Ltd $290,462,942 16.94% 6,106,011
Mega STATE STREET CORP $189,447,525 11.05% 3,982,500
Small GSK plc $153,205,226 8.93% 3,220,627
Mega GEODE CAPITAL MANAGEMENT, LLC $113,081,690 6.59% 2,377,164
Small SR One Capital Management, LP $96,983,955 5.65% 2,038,763
Mid Amova Asset Management Americas, Inc. $88,188,833 5.14% 1,853,875
Mega TWO SIGMA INVESTMENTS, LP $70,548,736 4.11% 1,483,051
Mega VANGUARD CAPITAL MANAGEMENT LLC $54,350,770 3.17% 1,142,543
Mid NEA Management Company, LLC $50,356,174 2.94% 1,058,570
Mega NORTHERN TRUST CORP Bank $38,159,747 2.22% 802,181
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $28,228,323 1.65% 593,406
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $26,943,648 1.57% 566,400
Mega VANGUARD FIDUCIARY TRUST CO Bank $25,815,382 1.51% 542,682
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $23,180,861 1.35% 487,300
Mid IQ EQ FUND MANAGEMENT (IRELAND) Ltd $19,069,718 1.11% 400,877
Large PEAK6 LLC $14,075,963 0.82% 295,900
Mid Vestmark Advisory Solutions, Inc. $12,214,977 0.71% 256,779
Mega RAYMOND JAMES FINANCIAL INC $10,478,433 0.61% 220,274
Mega Nuveen, LLC $9,074,737 0.53% 190,766
Mega Swiss National Bank Bank $8,072,629 0.47% 169,700
Mega TD Asset Management Inc $7,535,849 0.44% 158,416
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $7,487,324 0.44% 157,396
Large Pictet Asset Management Holding SA $7,326,112 0.43% 154,007
Large Squarepoint Ops LLC $7,305,562 0.43% 153,575
Mega LPL Financial LLC $7,232,637 0.42% 152,042
Small Versant Venture Management, LLC $7,079,890 0.41% 148,831
Mega D. E. Shaw & Co., Inc. $6,788,239 0.40% 142,700
Large ExodusPoint Capital Management, LP $6,428,086 0.37% 135,129
Large Marex Group plc $6,378,994 0.37% 134,097
Large Trexquant Investment LP $6,050,000 0.35% 127,181
Mid Reynders McVeigh Capital Management, LLC $5,871,945 0.34% 123,438
Mega AMERICAN CENTURY COMPANIES INC $5,731,614 0.33% 120,488
Large KBC Group NV $5,558,411 0.32% 116,847
Mega California Public Employees Retirement System Pension $5,523,209 0.32% 116,107
Mega RHUMBLINE ADVISERS $5,462,082 0.32% 114,822
Large PEAK6 LLC $5,166,292 0.30% 108,604
Large CONGRESS ASSET MANAGEMENT CO $5,155,208 0.30% 108,371
Mid Jump Financial, LLC $5,110,873 0.30% 107,439
Mid Private Advisor Group, LLC $5,073,911 0.30% 106,662
Small DIADEMA PARTNERS LP $5,056,691 0.29% 106,300
Mid Susquehanna Portfolio Strategies, LLC $5,012,593 0.29% 105,373
Mid CAPITAL INTERNATIONAL SARL $4,865,364 0.28% 102,278
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension $4,815,606 0.28% 101,232
Mid ALGERT GLOBAL LLC $4,605,727 0.27% 96,820
Mid GROUP ONE TRADING LLC $4,566,767 0.27% 96,001
Large CAPITAL FUND MANAGEMENT S.A. $4,555,778 0.27% 95,770
Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Mutual Fund $4,505,639 0.26% 94,716
Small Baker Chad R $4,438,281 0.26% 93,300
Mid HIMENSION CAPITAL (SINGAPORE) PTE. LTD. $4,399,321 0.26% 92,481
Small Slow Capital, Inc. $4,339,478 0.25% 91,223
Large Rafferty Asset Management, LLC $4,297,283 0.25% 90,336
Large Man Group plc $4,284,201 0.25% 90,061
Mid EverSource Wealth Advisors, LLC $4,266,217 0.25% 89,683
Large Zurcher Kantonalbank (Zurich Cantonalbank) Bank $4,092,399 0.24% 86,029
Mega DEUTSCHE BANK AG\ Bank $3,965,244 0.23% 83,356
Mega ENVESTNET ASSET MANAGEMENT INC $3,910,539 0.23% 82,206
Mega CITIGROUP INC $3,758,030 0.22% 79,000
Large COMMONWEALTH EQUITY SERVICES, LLC $3,733,674 0.22% 78,488
Mega VANGUARD ASSET MANAGEMENT, Ltd $3,656,325 0.21% 76,862
Mega Legal & General Group Plc $3,598,194 0.21% 75,640
Large Rockefeller Capital Management L.P. $3,488,068 0.20% 73,325
Large PEAK6 LLC $3,386,984 0.20% 71,200
Large HRT FINANCIAL LP $3,355,207 0.20% 70,532
Large JONES FINANCIAL COMPANIES LLLP $3,028,591 0.18% 63,666
Mid Concurrent Investment Advisors, LLC $2,969,461 0.17% 62,423
Large OSAIC HOLDINGS, INC. $2,856,862 0.17% 60,056
Large Cetera Investment Advisers $2,818,284 0.16% 59,245
Small Green Alpha Advisors, LLC $2,712,536 0.16% 57,022
Mid CAPITAL INTERNATIONAL LTD /CA/ $2,667,059 0.16% 56,066
Mid BENJAMIN EDWARDS INC $2,640,419 0.15% 55,506
Large Walleye Trading LLC $2,449,855 0.14% 51,500
Large Walleye Trading LLC $2,397,528 0.14% 50,400
Small Monashee Investment Management LLC $2,378,500 0.14% 50,000
Mid Curi Capital, LLC $2,364,513 0.14% 49,706
Large MetLife Investment Management, LLC $2,361,184 0.14% 49,636
Large Quantinno Capital Management LP $2,282,836 0.13% 47,989
Small Patriot Financial Group Insurance Agency, LLC Insurance $2,261,953 0.13% 47,550
Large Russell Investments Group, Ltd. $2,257,099 0.13% 47,448
Large LAZARD ASSET MANAGEMENT LLC $2,238,882 0.13% 47,065
Mega MANUFACTURERS LIFE INSURANCE COMPANY, THE Insurance $2,082,471 0.12% 43,777
Large Caption Management, LLC $2,069,295 0.12% 43,500
Large TUDOR INVESTMENT CORP ET AL $2,065,061 0.12% 43,411
Small Privium Fund Management B.V. $2,039,516 0.12% 42,874
Large Walleye Capital LLC $1,983,669 0.12% 41,700
Mid PROFUND ADVISORS LLC $1,950,798 0.11% 41,009
Small Palo Alto Investors LP $1,884,009 0.11% 39,605
Mega Vanguard Global Advisers, LLC $1,866,408 0.11% 39,235
Small Wealth Enhancement Trust Services, Inc. $1,848,237 0.11% 38,853
Large STIFEL FINANCIAL CORP $1,816,363 0.11% 38,183
Large Cambridge Investment Research Advisors, Inc. $1,807,279 0.11% 37,992
Large Creative Planning $1,789,012 0.10% 37,608
Large GUGGENHEIM CAPITAL LLC $1,697,345 0.10% 35,681
Small West Family Investments, Inc. $1,688,735 0.10% 35,500
Small Canal Insurance CO Insurance $1,669,707 0.10% 35,100
Large Corient Private Wealth LLC $1,655,959 0.10% 34,811
Large Capital International, Inc./CA/ $1,633,553 0.10% 34,340
Small Bouvel Investment Partners, LLC $1,546,928 0.09% 32,519
Large BLAIR WILLIAM & CO/IL $1,500,643 0.09% 31,546
Large State of New Jersey Common Pension Fund D Pension $1,394,419 0.08% 29,313
Mega BNP PARIBAS ARBITRAGE, SA $1,384,239 0.08% 29,099

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