DSGN · Design Therapeutics, Inc. · Holdings
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Institutional Ownership Trend
Holder Concentration
Across 136 13F filersWho Holds DSGN
Last 8 quarters through Sep 30, 2026 (filing window open)Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.
Jun 30, 2026, the newest closed quarter: 136 filers, like-for-like change +14.0%; actively managed books +12.4%; index-like books +21.4%.
| Holder type | Share | Filers | Change |
|---|---|---|---|
| Registered adviser | 71.0% | 70 | +6.3% |
| Exempt adviser | 1.0% | 2 | +112.0% |
| Adviser | 0.9% | 3 | +15.1% |
| Bank | 3.1% | 13 | +14.5% |
| Insurer | 0.5% | 1 | +389.3% |
| Benefit plan | 0.3% | 4 | +18.5% |
| Non-US | 0.2% | 5 | -45.8% |
| Holding company | 11.3% | 7 | +15.9% |
| Broker-dealer | 0.0% | 0 | — |
| Unknown | 11.7% | 31 | +78.6% |
| Style | Share | Filers | Change |
|---|---|---|---|
| Index-like | 18.9% | 17 | +21.4% |
| Systematic-like | 9.6% | 13 | -12.5% |
| Concentrated | 26.4% | 17 | -14.6% |
| Diversified active | 45.0% | 89 | +49.1% |
| Not measured | 0.0% | 0 | — |
| Unknown | 0.0% | 0 | — |
| Turnover | Share | Filers | Change |
|---|---|---|---|
| Low turnover | 46.6% | 68 | +2.3% |
| Medium turnover | 23.3% | 33 | +23.5% |
| High turnover | 19.9% | 24 | +19.0% |
| Unknown | 10.3% | 11 | +55.1% |
| Not measured | 0.0% | 0 | — |
| Holding horizon | Share | Filers | Change |
|---|---|---|---|
| Short horizon | 13.4% | 20 | +86.0% |
| Medium horizon | 33.1% | 22 | +11.8% |
| Long horizon | 31.7% | 82 | -5.9% |
| Unknown | 21.8% | 12 | +26.6% |
| Not measured | 0.0% | 0 | — |
| 13F book size | Share | Filers | Change |
|---|---|---|---|
| Under $1B | 9.0% | 23 | +25.7% |
| $1B to $10B | 38.9% | 33 | +43.6% |
| $10B to $100B | 25.6% | 33 | -13.7% |
| $100B or more | 26.5% | 47 | +11.3% |
| Not measured | 0.0% | 0 | — |
| Client base | Share | Filers | Change |
|---|---|---|---|
| Individuals and high net worth | 0.4% | 21 | +15.8% |
| Pooled investment vehicles | 51.7% | 24 | -2.5% |
| Registered funds and BDCs | 9.0% | 10 | +30.7% |
| Pension and profit sharing plans | 0.0% | 1 | 0.0% |
| Insurance companies | 0.1% | 2 | +31.3% |
| Governments and sovereign funds | 0.8% | 3 | -16.8% |
| Other investment advisers | 0.0% | 1 | -1.5% |
| Diversified | 8.6% | 7 | +56.6% |
| Unknown | 29.4% | 67 | +40.6% |
| Private funds | Share | Filers | Change |
|---|---|---|---|
| Hedge funds | 30.9% | 27 | +9.1% |
| Private equity funds | 18.9% | 6 | -0.1% |
| Venture capital funds | 6.9% | 2 | -39.1% |
| Real estate funds | 0.0% | 2 | +1038.9% |
| Securitized asset funds | 0.0% | 1 | 0.0% |
| Other private funds | 2.5% | 6 | +46.0% |
| Mixed private funds | 4.3% | 2 | +3918.0% |
| Private funds, type not stated | 0.9% | 1 | +41.4% |
| No private funds | 7.6% | 25 | +23.0% |
| Unknown | 27.9% | 64 | +36.8% |
| Location | Share | Filers | Change |
|---|---|---|---|
| United States | 98.3% | 117 | +13.7% |
| Outside the US | 1.7% | 19 | +38.3% |
The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.
How the mix is measured
Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.
Excluded 1 holder with no observed 2026-03-31 13F and 1 holder with no observed 2026-06-30 13F.
Conviction and Crowding
136 13F filers, quarter ended Jun 30, 2026Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.
Managers in the top fifth by current three-year FundScore alpha were net buyers of $0 (0 buying, 0 selling).
Estimated Holder Cost Basis
Quarter ended Jun 30, 2026, on that quarter's share basisEstimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.
Estimated cost covers 54.7% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.
Shared Holders
Companies DSGN's active holders also own, quarter ended Jun 30, 2026| # | Company | Shared holders |
|---|---|---|
| 1 | TENX Tenax Therapeutics, Inc. | 6 |
| 2 | VTVT vTv Therapeutics Inc. | 3 |
| 3 | WHWK Whitehawk Therapeutics, Inc. | 5 |
| 4 | LBRX Lb Pharmaceuticals Inc | 6 |
| 5 | NERV Minerva Neurosciences, Inc. | 4 |
| 6 | ERAS Erasca, Inc. | 8 |
| 7 | DBVT DBV Technologies S.A. | 5 |
| 8 | SEPN Septerna, Inc. | 5 |
| 9 | IDYA IDEAYA Biosciences, Inc. | 6 |
| 10 | AVTX Avalo Therapeutics, Inc. | 7 |
Shareholder Targets
13F filers that own its peers but not DSGN, quarter ended Jun 30, 2026Found through its holder-overlap peers: TENX, VTVT, WHWK, LBRX, NERV, ERAS, DBVT, SEPN, IDYA, AVTX, CTMX, TYRA, RCUS, IRON, EWTX, IMCR, AVBP, REPL, ACHV, RAPP. 568 filers in all.
| # | Filer | In peers | Largest peers |
|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. Registered adviser, Concentrated | $1,234,281,390 6 held | TYRA, EWTX, SEPN |
| 2 | GILEAD SCIENCES, INC. Unknown, Concentrated | $968,825,350 1 held | RCUS |
| 3 | Jupiter Topco LLC Unknown, Diversified active | $825,633,233 15 held | IDYA, EWTX, TYRA |
| 4 | ORBIMED ADVISORS LLC Registered adviser, Diversified active | $795,390,243 7 held | EWTX, AVBP, IRON |
| 5 | Paradigm Biocapital Advisors LP Registered adviser, Concentrated | $680,751,262 4 held | EWTX, ERAS, TYRA |
| 6 | RTW INVESTMENTS, LP Registered adviser, Diversified active | $594,813,802 7 held | ERAS, IMCR, REPL |
| 7 | TRV GP V, LLC Unknown, Unknown | $469,869,618 2 held | RAPP, SEPN |
| 8 | T. Rowe Price Investment Management, Inc. Adviser, Diversified active | $422,684,917 3 held | ERAS, RCUS, RAPP |
| 9 | SUVRETTA CAPITAL MANAGEMENT, LLC Registered adviser, Diversified active | $372,416,151 4 held | AVBP, RCUS, REPL |
| 10 | Venrock Adviser, LLC Registered adviser, Concentrated | $364,425,198 3 held | ERAS, CTMX, ACHV |
Fund Ownership of DSGN by Fund Type
Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026Index funds and index ETFs hold 7.48% of shares outstanding.
| Fund type | Of shares outstanding | Shares |
|---|---|---|
| Index funds | 1.65% | 1,034,803 |
| Index ETFs | 5.82% | 3,644,000 |
| Active ETFs | 0.61% | 384,406 |
| Active funds | 2.75% | 1,719,035 |
| Unclassified | 0.32% | 198,846 |
| All registered funds | 11.16% | 6,981,090 |
How fund types are measured
Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Mid SR One Capital Management, LP Registered adviser | $94,438,107 | 14.55% | 6,526,476 | Shares | 2026-08-12 | |
| Mid Logos Global Management LP Registered adviser | $43,410,000 | 6.69% | 3,000,000 | Shares | 2026-08-14 | |
| Large BAKER BROS. ADVISORS LP Registered adviser | $38,756,882 | 5.97% | 2,678,430 | Shares | 2026-08-14 | |
| Large Driehaus Capital Management LLC Registered adviser | $38,506,334 | 5.93% | 2,661,115 | Shares | 2026-08-14 | |
| Mega BlackRock, Inc. Holding company | $38,490,543 | 5.93% | 2,660,024 | Shares | 2026-08-07 | |
| Large Point72 Asset Management, L.P. Registered adviser | $34,242,574 | 5.28% | 2,366,453 | Shares | 2026-08-14 | |
| Small Trails Edge Capital Partners, LP | $28,958,550 | 4.46% | 2,001,282 | Shares | 2026-08-14 | |
| Mid Frazier Life Sciences Management, L.P. Registered adviser | $26,188,587 | 4.03% | 1,809,854 | Shares | 2026-08-14 | |
| Mid Vivo Capital, LLC Registered adviser | $23,338,706 | 3.60% | 1,612,903 | Shares | 2026-08-14 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC Registered adviser | $22,732,688 | 3.50% | 1,571,022 | Shares | 2026-08-13 | |
| Large Caption Management, LLC Registered adviser | $21,705,000 | 3.34% | 1,500,000 | Call | 2026-08-14 | |
| Large Caption Management, LLC Registered adviser | $16,178,878 | 2.49% | 1,118,098 | Shares | 2026-08-14 | |
| Small Almitas Capital LLC Registered adviser | $14,859,141 | 2.29% | 1,026,893 | Shares | 2026-08-17 | |
| Mega GEODE CAPITAL MANAGEMENT, LLC Registered adviser | $13,868,293 | 2.14% | 958,417 | Shares | 2026-08-12 | |
| Mid Sofinnova Investments, Inc. | $12,518,503 | 1.93% | 865,135 | Shares | 2026-08-14 | |
| Mega FMR LLC Holding company | $11,235,405 | 1.73% | 776,462 | Shares | 2026-08-13 | |
| Mega MORGAN STANLEY Holding company | $11,075,697 | 1.71% | 765,425 | Shares | 2026-08-13 | |
| Mega STATE STREET CORP Bank | $10,653,117 | 1.64% | 736,221 | Shares | 2026-09-22 | |
| Large Woodline Partners LP Registered adviser | $10,134,122 | 1.56% | 700,354 | Shares | 2026-08-14 | |
| Mega DIMENSIONAL FUND ADVISORS LP Registered adviser | $10,052,929 | 1.55% | 694,743 | Shares | 2026-08-11 | |
| Mega GOLDMAN SACHS GROUP INC Holding company | $9,500,769 | 1.46% | 656,584 | Shares | 2026-08-14 | |
| Large JACOBS LEVY EQUITY MANAGEMENT, INC Registered adviser | $8,184,188 | 1.26% | 565,597 | Shares | 2026-08-14 | |
| Large ACADIAN ASSET MANAGEMENT LLC | $7,777,321 | 1.20% | 537,479 | Shares | 2026-08-13 | |
| Mid Siren, L.L.C. | $7,570,877 | 1.17% | 523,212 | Shares | 2026-08-13 | |
| Mega Qube Research & Technologies Ltd Exempt adviser | $6,324,533 | 0.97% | 437,079 | Shares | 2026-08-14 | |
| Large RENAISSANCE TECHNOLOGIES LLC Registered adviser | $5,613,101 | 0.86% | 387,913 | Shares | 2026-08-13 | |
| Mid KENNEDY CAPITAL MANAGEMENT LLC Registered adviser | $5,557,000 | 0.86% | 384,036 | Shares | 2026-08-14 | |
| Mega NORTHERN TRUST CORP Bank | $5,110,758 | 0.79% | 353,197 | Shares | 2026-08-13 | |
| Mid ALGERT GLOBAL LLC Registered adviser | $4,284,349 | 0.66% | 296,085 | Shares | 2026-08-13 | |
| Small ACUTA CAPITAL PARTNERS, LLC Adviser | $4,088,701 | 0.63% | 282,564 | Shares | 2026-08-14 | |
| Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC Registered adviser | $3,925,190 | 0.60% | 271,264 | Shares | 2026-08-14 | |
| Mega VANGUARD PORTFOLIO MANAGEMENT LLC Registered adviser | $3,638,365 | 0.56% | 251,442 | Shares | 2026-08-13 | |
| Mega VANGUARD FIDUCIARY TRUST CO | $3,331,022 | 0.51% | 230,202 | Shares | 2026-08-13 | |
| Large PRUDENTIAL FINANCIAL INC Insurer | $3,243,739 | 0.50% | 224,170 | Shares | 2026-08-12 | |
| Mega D. E. Shaw & Co., Inc. | $2,830,983 | 0.44% | 195,645 | Shares | 2026-08-14 | |
| Mid Eversept Partners, LP Registered adviser | $2,749,300 | 0.42% | 190,000 | Shares | 2026-08-14 | |
| Small KVP Capital Advisors, LP Registered adviser | $2,676,950 | 0.41% | 185,000 | Shares | 2026-08-13 | |
| Mid J. Goldman & Co LP Registered adviser | $2,557,861 | 0.39% | 176,770 | Shares | 2026-08-14 | |
| Mega MILLENNIUM MANAGEMENT LLC Registered adviser | $2,137,421 | 0.33% | 147,714 | Shares | 2026-08-14 | |
| Mega RAYMOND JAMES FINANCIAL INC | $2,004,398 | 0.31% | 138,521 | Shares | 2026-08-14 | |
| Large Balyasny Asset Management L.P. Registered adviser | $1,607,660 | 0.25% | 111,103 | Shares | 2026-08-14 | |
| Small Elmind Capital, LP Registered adviser | $1,561,313 | 0.24% | 107,900 | Shares | 2026-08-14 | |
| Mega Nuveen, LLC | $1,515,499 | 0.23% | 104,734 | Shares | 2026-08-11 | |
| Small DAFNA Capital Management LLC Registered adviser | $1,484,622 | 0.23% | 102,600 | Shares | 2026-08-14 | |
| Mega Bank of New York Mellon Corp Bank | $1,332,237 | 0.21% | 92,069 | Shares | 2026-08-06 | |
| Mid China Universal Asset Management Co., Ltd. | $1,301,431 | 0.20% | 89,940 | Shares | 2026-07-24 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $1,186,120 | 0.18% | 81,971 | Shares | 2026-09-02 | |
| Mid SummitTX Capital, L.P. Registered adviser | $1,167,193 | 0.18% | 80,663 | Shares | 2026-08-14 | |
| Mega AMERICAN CENTURY COMPANIES INC | $1,111,657 | 0.17% | 76,825 | Shares | 2026-08-12 | |
| Small Palumbo Wealth Management LLC Registered adviser | $1,038,135 | 0.16% | 71,744 | Shares | 2026-08-12 | |
| Mega AQR CAPITAL MANAGEMENT LLC Registered adviser | $1,029,016 | 0.16% | 71,114 | Shares | 2026-08-14 | |
| Mega AMERIPRISE FINANCIAL INC Adviser | $978,143 | 0.15% | 67,598 | Shares | 2026-08-14 | |
| Mega Russell Investments Group, Ltd. | $967,447 | 0.15% | 66,859 | Shares | 2026-08-06 | |
| Large ALPS ADVISORS INC Registered adviser | $917,267 | 0.14% | 63,391 | Shares | 2026-07-29 | |
| Large STATE OF WISCONSIN INVESTMENT BOARD Benefit plan | $857,333 | 0.13% | 59,249 | Shares | 2026-08-14 | |
| Large STRS OHIO Benefit plan | $730,735 | 0.11% | 50,500 | Shares | 2026-07-30 | |
| Small Verdad Advisers, LP | $688,149 | 0.11% | 47,557 | Shares | 2026-08-14 | |
| Mega BANK OF AMERICA CORP /DE/ Bank | $632,743 | 0.10% | 43,728 | Shares | 2026-08-14 | |
| Mega ALLIANCEBERNSTEIN L.P. Registered adviser | $625,538 | 0.10% | 43,230 | Shares | 2026-08-14 | |
| Large ExodusPoint Capital Management, LP Registered adviser | $597,408 | 0.09% | 41,286 | Shares | 2026-08-14 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $578,800 | 0.09% | 40,000 | Call | 2026-08-14 | |
| Mega RHUMBLINE ADVISERS Registered adviser | $551,770 | 0.09% | 38,132 | Shares | 2026-08-12 | |
| Mega Vanguard Global Advisers, LLC Registered adviser | $514,176 | 0.08% | 35,534 | Shares | 2026-08-13 | |
| Mega UBS Group AG Bank | $502,990 | 0.08% | 34,761 | Shares | 2026-08-13 | |
| Mid Susquehanna Portfolio Strategies, LLC | $482,936 | 0.07% | 33,375 | Shares | 2026-08-14 | |
| Mega TWO SIGMA INVESTMENTS, LP Registered adviser | $476,424 | 0.07% | 32,925 | Shares | 2026-08-14 | |
| Mega CANADA PENSION PLAN INVESTMENT BOARD Non-US | $471,722 | 0.07% | 32,600 | Shares | 2026-08-14 | |
| Mega DEUTSCHE BANK AG\ Non-US | $442,970 | 0.07% | 30,613 | Shares | 2026-08-07 | |
| Small Virtus Investment Advisers, LLC Registered adviser | $431,596 | 0.07% | 29,827 | Shares | 2026-08-11 | |
| Large Squarepoint Ops LLC Registered adviser | $428,746 | 0.07% | 29,630 | Shares | 2026-08-14 | |
| Mid Y-Intercept (Hong Kong) Ltd Exempt adviser | $408,122 | 0.06% | 32,468 | Shares | 2026-10-16 | |
| Large Trexquant Investment LP Registered adviser | $407,330 | 0.06% | 28,150 | Shares | 2026-08-14 | |
| Mega WELLS FARGO & COMPANY/MN Bank | $406,201 | 0.06% | 28,072 | Shares | 2026-08-14 | |
| Mid OPPENHEIMER & CO INC | $397,790 | 0.06% | 31,646 | Shares | 2026-10-26 | |
| Large Corient Private Wealth LLC Registered adviser | $393,135 | 0.06% | 27,169 | Shares | 2026-08-27 | |
| Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC Registered adviser | $390,690 | 0.06% | 27,000 | Shares | 2026-08-14 | |
| Large Quantinno Capital Management LP Registered adviser | $389,257 | 0.06% | 26,901 | Shares | 2026-08-13 | |
| Mega PRICE T ROWE ASSOCIATES INC /MD/ Registered adviser | $370,518 | 0.06% | 25,606 | Shares | 2026-08-14 | |
| Mega SEI INVESTMENTS CO Holding company | $329,047 | 0.05% | 22,740 | Shares | 2026-08-14 | |
| Mid XTX Topco Ltd | $323,882 | 0.05% | 22,383 | Shares | 2026-08-14 | |
| Small AlphaCentric Advisors LLC Registered adviser | $311,640 | 0.05% | 21,537 | Shares | 2026-07-24 | |
| Mega Invesco Ltd. Adviser | $310,076 | 0.05% | 21,429 | Shares | 2026-08-14 | |
| Large PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO Benefit plan | $299,529 | 0.05% | 20,700 | Shares | 2026-08-17 | |
| Large MetLife Investment Management, LLC Registered adviser | $298,212 | 0.05% | 20,609 | Shares | 2026-08-14 | |
| Mega WELLINGTON MANAGEMENT GROUP LLP Holding company | $280,718 | 0.04% | 19,400 | Shares | 2026-08-14 | |
| Mega JPMORGAN CHASE & CO Bank | $244,599 | 0.04% | 16,904 | Shares | 2026-08-12 | |
| Mega CITIGROUP INC Bank | $229,782 | 0.04% | 15,880 | Shares | 2026-08-03 | |
| Mega Creative Planning Registered adviser | $229,262 | 0.04% | 15,844 | Shares | 2026-08-13 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $226,455 | 0.03% | 15,650 | Shares | 2026-08-14 | |
| Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | $205,054 | 0.03% | 14,171 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $201,133 | 0.03% | 13,900 | Call | 2026-09-02 | |
| Mid SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC | $181,641 | 0.03% | 12,553 | Shares | 2026-08-14 | |
| Mega ROYAL BANK OF CANADA Bank | $177,314 | 0.03% | 12,254 | Shares | 2026-08-14 | |
| Mega BARCLAYS PLC Bank | $169,400 | 0.03% | 11,707 | Shares | 2026-08-14 | |
| Large NEW YORK STATE COMMON RETIREMENT FUND | $156,652 | 0.02% | 10,826 | Shares | 2026-07-29 | |
| Mid GSA CAPITAL PARTNERS LLP Registered adviser | $149,446 | 0.02% | 10,328 | Shares | 2026-08-06 | |
| Large Police & Firemen's Retirement System of New Jersey | $142,515 | 0.02% | 9,849 | Shares | 2026-07-23 | |
| Mega BNP PARIBAS ARBITRAGE, SA Non-US | $83,216 | 0.01% | 5,751 | Shares | 2026-08-13 | |
| Large Clearstead Advisors, LLC Registered adviser | $81,176 | 0.01% | 5,610 | Shares | 2026-08-06 | |
| Mid Tower Research Capital LLC (TRC) | $71,018 | 0.01% | 4,908 | Shares | 2026-08-11 |
Showing the top 100 of 138 holders. Create a free account to see every holder, past quarters, search, filters and CSV export.