DSGN · Design Therapeutics, Inc. · Shareholders & Ownership

$11.12 +0.48 (+4.51%)

Russell 2000 member Rebalance outlook locked

Market Cap

$665.87M

62.58M

Volume · Oct 20 231K Avg daily vol (3M) 599.69K

Every disclosed holder of DSGN in one list: 13F institutions, Schedule 13D and 13G filers, insiders (Forms 3, 4 and 5) and registered funds, each from its own latest filing. Holders nest by CIK and SEC reporting links, never by name, and each is summed once.

How the holder list picks a filing →

Who Owns DSGN

13F quarter Sep 30, 2026, combined view: filers that have not filed yet carry their Jun 30, 2026 positions

No chart: the summed disclosures exceed shares outstanding, so they are not parts of one whole.

Holder group	Holders	Shares	% Out	Summed
Institutional (13F)	135	43,321,143	69.22%	Yes
Insiders (Forms 3, 4, 5)	1	20,000	0.03%	Yes
13D/G-only blocks	4	20,159,122	32.21%	Yes
Remaining	—	918,614	-1.47%	Negative
Registered funds (N-PORT, not summed)	152	7,305,214	11.67%	No

Shares outstanding: 62,581,651, the issuer's latest cover-page count restated onto today's split basis.

Remaining is negative: the summed disclosures exceed shares outstanding, as when filings are dated at different times or holders that do not disclose their links count the same shares. It is flagged, not clipped.

13D/G-only counts each filer's latest 13D or 13G that no 13F report of the listing contains, that names no 13F filer and that no counted insider files. Funds are never summed: their shares sit inside their advisers' 13F reports.

Holders of DSGN

One row per holder Every filing By ultimate parent

All 13F Funds Insiders 13D/G Non-US

#	Holder	Shares	% Out	Change	As of	Notes
1	SR One Capital Fund I Aggregator, LP 13D CIK 1848319 · Unknown · Mar 9, 2026	6,526,476	10.43%	—	Mar 9, 2026
2	SR One Capital Management, LP 13F CIK 1910264 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	6,526,476	10.43%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
3	Sirenia Capital Management LP 13G CIK 2115022 · Registered investment adviser · Jun 30, 2026 Rule 13d-1(b), qualified institution	5,963,936	9.53%	—	Jun 30, 2026	Rule 13d-1(b), qualified institution
4	Light Irrevocable Trust #1 dated April 22, 2019 13G CIK 1849306 · Unknown · Dec 31, 2024 Rule 13d-1(d), exempt investor	3,834,355	6.13%	—	Dec 31, 2024	Rule 13d-1(d), exempt investor
5	Star Irrevocable Trust #1 dated April 22, 2019 13G CIK 1849576 · Unknown · Dec 31, 2024 Rule 13d-1(d), exempt investor	3,834,355	6.13%	—	Dec 31, 2024	Rule 13d-1(d), exempt investor
6	Logos Global Management LP 13F CIK 1792126 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	3,000,000	4.79%	+1,050,000	Jun 30, 2026	carried, not yet filed for the newest quarter
7	BAKER BROS. ADVISORS LP 13F CIK 1263508 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	2,678,430	4.28%	+92,452	Jun 30, 2026	carried, not yet filed for the newest quarter
8	Driehaus Capital Management LLC 13F CIK 938206 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	2,661,115	4.25%	+916,128	Jun 30, 2026	carried, not yet filed for the newest quarter
8.1	Driehaus Micro Cap Growth Fund Fund S000042829 · Registered fund · Jun 30, 2026 Driehaus Mutual Funds, not summed	135,259	0.22%	+82,496	Jun 30, 2026	Driehaus Mutual Funds, not summed
9	BlackRock, Inc. 13F CIK 2012383 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	2,660,024	4.25%	+526,260	Jun 30, 2026	carried, not yet filed for the newest quarter
9.1	iShares Russell 2000 ETF Fund S000004344 · Registered fund · Jun 30, 2026 iShares Trust, not summed	816,383	1.30%	+230,474	Jun 30, 2026	iShares Trust, not summed
9.2	iShares Russell 2000 Growth ETF Fund S000004343 · Registered fund · Jun 30, 2026 iShares Trust, not summed	288,998	0.46%	—	Jun 30, 2026	iShares Trust, not summed
9.3	iShares Biotechnology ETF Fund S000004350 · Registered fund · Jun 30, 2026 iShares Trust, not summed	265,739	0.42%	+29,880	Jun 30, 2026	iShares Trust, not summed
9.4	iShares Micro-Cap ETF Fund S000004439 · Registered fund · Jun 30, 2026 iShares Trust, not summed	103,523	0.17%	+43,317	Jun 30, 2026	iShares Trust, not summed
9.5	iShares Genomics Immunology and Healthcare ETF Fund S000065599 · Registered fund · Jul 31, 2026 iShares Trust, not summed	81,808	0.13%	+26,047	Jul 31, 2026	iShares Trust, not summed
10	Point72 Asset Management, L.P. 13F CIK 1603466 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	2,366,453	3.78%	-356,301	Jun 30, 2026	carried, not yet filed for the newest quarter
10.1	Point72 Asset Management, L.P. 13G CIK 1603466 · Registered investment adviser · Jun 30, 2026 Rule 13d-1(c), passive investor, not summed	2,366,453	3.78%	-831,311	Jun 30, 2026	Rule 13d-1(c), passive investor, not summed
11	Trails Edge Capital Partners, LP 13F CIK 2077247 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	2,001,282	3.20%	+1,149,269	Jun 30, 2026	carried, not yet filed for the newest quarter
12	Frazier Life Sciences Management, L.P. 13F CIK 1892134 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,809,854	2.89%	+1,809,854	Jun 30, 2026	carried, not yet filed for the newest quarter
13	Vivo Capital, LLC 13F CIK 1674712 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,612,903	2.58%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
14	VANGUARD CAPITAL MANAGEMENT LLC 13F CIK 2100119 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,571,022	2.51%	+221,172	Jun 30, 2026	carried, not yet filed for the newest quarter
15	VANGUARD TOTAL STOCK MARKET INDEX FUND Fund S000002848 · Registered fund · Jun 30, 2026 VANGUARD INDEX FUNDS, not summed	1,161,075	1.86%	+176,300	Jun 30, 2026	VANGUARD INDEX FUNDS, not summed
16	Caption Management, LLC 13F CIK 1706766 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,118,098	1.79%	+1,031,390	Jun 30, 2026	carried, not yet filed for the newest quarter
17	Almitas Capital LLC 13F CIK 1596468 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,026,893	1.64%	-503,442	Jun 30, 2026	carried, not yet filed for the newest quarter
18	William Arsani Insider CIK 1848372 · Aug 13, 2025 Director, issuer-wide, not summed	1,000,000	1.60%	—	Aug 13, 2025	Director, issuer-wide, not summed
19	GEODE CAPITAL MANAGEMENT, LLC 13F CIK 1214717 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	958,417	1.53%	+265,899	Jun 30, 2026	carried, not yet filed for the newest quarter
20	Sofinnova Investments, Inc. 13F CIK 1631134 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	865,135	1.38%	+865,135	Jun 30, 2026	carried, not yet filed for the newest quarter
21	FMR LLC 13F CIK 315066 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	776,462	1.24%	-21,949	Jun 30, 2026	carried, not yet filed for the newest quarter
21.1	Select Biotechnology Portfolio Fund S000007486 · Registered fund · May 31, 2026 Fidelity Select Portfolios, not summed	534,931	0.85%	-81,900	May 31, 2026	Fidelity Select Portfolios, not summed
21.2	Fidelity Small Cap Index Fund Fund S000033638 · Registered fund · Jul 31, 2026 Fidelity Salem Street Trust, not summed	337,104	0.54%	+101,312	Jul 31, 2026	Fidelity Salem Street Trust, not summed
21.3	Fidelity Enhanced Small Cap Core ETF Fund S000081807 · Registered fund · Jun 30, 2026 Fidelity Covington Trust, not summed	204,949	0.33%	+63,663	Jun 30, 2026	Fidelity Covington Trust, not summed
21.4	Fidelity Extended Market Index Fund Fund S000006021 · Registered fund · May 31, 2026 Fidelity Concord Street Trust, not summed	152,816	0.24%	-3,701	May 31, 2026	Fidelity Concord Street Trust, not summed
21.5	Fidelity SAI Small-Mid Cap Momentum Index Fund Fund S000050321 · Registered fund · Jul 31, 2026 Fidelity Salem Street Trust, not summed	90,496	0.14%	—	Jul 31, 2026	Fidelity Salem Street Trust, not summed
22	MORGAN STANLEY 13F CIK 895421 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	765,425	1.22%	+108,860	Jun 30, 2026	carried, not yet filed for the newest quarter
23	STATE STREET CORP 13F CIK 93751 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	736,221	1.18%	+76,646	Jun 30, 2026	carried, not yet filed for the newest quarter
23.1	STATE STREET SMALL/MID CAP EQUITY INDEX PORTFOLIO Fund S000050332 · Registered fund · Jun 30, 2026 STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed	8,900	0.01%	+1,200	Jun 30, 2026	STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
23.2	State Street Total Return V.I.S. Fund Fund S000001637 · Registered fund · Jun 30, 2026 STATE STREET VARIABLE INSURANCE SERIES FUNDS INC, not summed	777	0.00%	+273	Jun 30, 2026	STATE STREET VARIABLE INSURANCE SERIES FUNDS INC, not summed
24	Woodline Partners LP 13F CIK 1784547 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	700,354	1.12%	-261,147	Jun 30, 2026	carried, not yet filed for the newest quarter
25	DIMENSIONAL FUND ADVISORS LP 13F CIK 354204 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	694,743	1.11%	+262,903	Jun 30, 2026	carried, not yet filed for the newest quarter
25.1	Dimensional U.S. Small Cap ETF Fund S000070906 · Registered fund · Jul 31, 2026 Dimensional ETF Trust, not summed	156,210	0.25%	+33,428	Jul 31, 2026	Dimensional ETF Trust, not summed
25.2	U.S. SMALL CAP PORTFOLIO Fund S000000971 · Registered fund · Jul 31, 2026 DFA INVESTMENT DIMENSIONS GROUP INC, not summed	135,805	0.22%	+30,136	Jul 31, 2026	DFA INVESTMENT DIMENSIONS GROUP INC, not summed
25.3	U.S. MICRO CAP PORTFOLIO Fund S000000948 · Registered fund · Jul 31, 2026 DFA INVESTMENT DIMENSIONS GROUP INC, not summed	113,325	0.18%	+56,483	Jul 31, 2026	DFA INVESTMENT DIMENSIONS GROUP INC, not summed
25.4	Dimensional U.S. Core Equity 2 ETF Fund S000070903 · Registered fund · Jul 31, 2026 Dimensional ETF Trust, not summed	32,522	0.05%	+30,512	Jul 31, 2026	Dimensional ETF Trust, not summed
25.5	U.S. VECTOR EQUITY PORTFOLIO Fund S000000982 · Registered fund · Jul 31, 2026 DFA INVESTMENT DIMENSIONS GROUP INC, not summed	24,232	0.04%	—	Jul 31, 2026	DFA INVESTMENT DIMENSIONS GROUP INC, not summed
26	GOLDMAN SACHS GROUP INC 13F CIK 886982 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	656,584	1.05%	+151,866	Jun 30, 2026	carried, not yet filed for the newest quarter
26.1	Goldman Sachs Small Cap Equity Insights Fund Fund S000009329 · Registered fund · Jul 31, 2026 Goldman Sachs Trust, not summed	16,819	0.03%	-61,236	Jul 31, 2026	Goldman Sachs Trust, not summed
26.2	Goldman Sachs Small Cap Growth Insights Fund Fund S000014930 · Registered fund · Jul 31, 2026 Goldman Sachs Trust, not summed	14,780	0.02%	+595	Jul 31, 2026	Goldman Sachs Trust, not summed
26.3	Goldman Sachs Absolute Return Tracker Fund Fund S000020314 · Registered fund · Jun 30, 2026 GOLDMAN SACHS TRUST, not summed	8,080	0.01%	+4,174	Jun 30, 2026	GOLDMAN SACHS TRUST, not summed
26.4	Goldman Sachs Variable Insurance Trust Small Cap Equity Insights Fund Fund S000009355 · Registered fund · Jun 30, 2026 Goldman Sachs Variable Insurance Trust, not summed	3,056	0.00%	-19,252	Jun 30, 2026	Goldman Sachs Variable Insurance Trust, not summed
27	JACOBS LEVY EQUITY MANAGEMENT, INC 13F CIK 884414 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	565,597	0.90%	+276,212	Jun 30, 2026	carried, not yet filed for the newest quarter
28	ACADIAN ASSET MANAGEMENT LLC 13F CIK 916542 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	537,479	0.86%	-79,002	Jun 30, 2026	carried, not yet filed for the newest quarter
29	Siren, L.L.C. 13F CIK 2005245 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	523,212	0.84%	+523,212	Jun 30, 2026	carried, not yet filed for the newest quarter
30	Qube Research & Technologies Ltd 13F CIK 1729829 · Exempt reporting adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	437,079	0.70%	+402,896	Jun 30, 2026	carried, not yet filed for the newest quarter
31	RENAISSANCE TECHNOLOGIES LLC 13F CIK 1037389 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	387,913	0.62%	-20,287	Jun 30, 2026	carried, not yet filed for the newest quarter
32	KENNEDY CAPITAL MANAGEMENT LLC 13F CIK 884589 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	384,036	0.61%	+112,482	Jun 30, 2026	carried, not yet filed for the newest quarter
32.1	Kennedy Capital Small Cap Growth Fund Fund S000076117 · Registered fund · Jun 30, 2026 INVESTMENT MANAGERS SERIES TRUST II, not summed	272	0.00%	—	Jun 30, 2026	INVESTMENT MANAGERS SERIES TRUST II, not summed
33	VANGUARD EXTENDED MARKET INDEX FUND Fund S000002841 · Registered fund · Jun 30, 2026 VANGUARD INDEX FUNDS, not summed	373,877	0.60%	+40,704	Jun 30, 2026	VANGUARD INDEX FUNDS, not summed
34	NORTHERN TRUST CORP 13F CIK 73124 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	353,197	0.56%	+52,918	Jun 30, 2026	carried, not yet filed for the newest quarter
34.1	Small Cap Core Fund Fund S000001244 · Registered fund · Jun 30, 2026 Northern Funds, not summed	15,746	0.03%	-676	Jun 30, 2026	Northern Funds, not summed
34.2	Small Cap Index Fund Fund S000001245 · Registered fund · Jun 30, 2026 Northern Funds, not summed	15,135	0.02%	+3,433	Jun 30, 2026	Northern Funds, not summed
35	ALGERT GLOBAL LLC 13F CIK 1275218 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	296,085	0.47%	+91,346	Jun 30, 2026	carried, not yet filed for the newest quarter
36	ACUTA CAPITAL PARTNERS, LLC 13F CIK 1582844 · Investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	282,564	0.45%	+136,664	Jun 30, 2026	carried, not yet filed for the newest quarter
37	CHARLES SCHWAB INVESTMENT MANAGEMENT INC 13F CIK 884546 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	271,264	0.43%	+29,779	Jun 30, 2026	carried, not yet filed for the newest quarter
37.1	Schwab U.S. Small-Cap ETF Fund S000026636 · Registered fund · May 31, 2026 SCHWAB STRATEGIC TRUST, not summed	144,577	0.23%	-2,208	May 31, 2026	SCHWAB STRATEGIC TRUST, not summed
37.2	Schwab Small-Cap Index Fund Fund S000005912 · Registered fund · Jul 31, 2026 SCHWAB CAPITAL TRUST, not summed	74,808	0.12%	+21,873	Jul 31, 2026	SCHWAB CAPITAL TRUST, not summed
37.3	Schwab U.S. Broad Market ETF Fund S000026631 · Registered fund · May 31, 2026 SCHWAB STRATEGIC TRUST, not summed	26,443	0.04%	0	May 31, 2026	SCHWAB STRATEGIC TRUST, not summed
37.4	Schwab Total Stock Market Index Fund Fund S000005913 · Registered fund · Jul 31, 2026 SCHWAB CAPITAL TRUST, not summed	15,000	0.02%	0	Jul 31, 2026	SCHWAB CAPITAL TRUST, not summed
38	VANGUARD PORTFOLIO MANAGEMENT LLC 13F CIK 2100121 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	251,442	0.40%	+112,877	Jun 30, 2026	carried, not yet filed for the newest quarter
39	VANGUARD FIDUCIARY TRUST CO 13F CIK 933478 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	230,202	0.37%	+34,544	Jun 30, 2026	carried, not yet filed for the newest quarter
40	PRUDENTIAL FINANCIAL INC 13F CIK 1137774 · Insurance company · Jun 30, 2026 carried, not yet filed for the newest quarter	224,170	0.36%	+178,360	Jun 30, 2026	carried, not yet filed for the newest quarter
41	D. E. Shaw & Co., Inc. 13F CIK 1009207 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	195,645	0.31%	-274,625	Jun 30, 2026	carried, not yet filed for the newest quarter
42	Eversept Partners, LP 13F CIK 1697013 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	190,000	0.30%	+190,000	Jun 30, 2026	carried, not yet filed for the newest quarter
43	KVP Capital Advisors, LP 13F CIK 1858198 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	185,000	0.30%	+185,000	Jun 30, 2026	carried, not yet filed for the newest quarter
44	J. Goldman & Co LP 13F CIK 1412741 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	176,770	0.28%	+176,770	Jun 30, 2026	carried, not yet filed for the newest quarter
45	MILLENNIUM MANAGEMENT LLC 13F CIK 1273087 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	147,714	0.24%	+38,786	Jun 30, 2026	carried, not yet filed for the newest quarter
46	NORTH SQUARE DYNAMIC SMALL CAP FUND Fund S000063485 · Registered fund · May 31, 2026 Exchange Place Advisors Trust, not summed	143,991	0.23%	+28,540	May 31, 2026	Exchange Place Advisors Trust, not summed
47	RAYMOND JAMES FINANCIAL INC 13F CIK 720005 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	138,521	0.22%	+30,072	Jun 30, 2026	carried, not yet filed for the newest quarter
48	VANGUARD RUSSELL 2000 INDEX FUND Fund S000030003 · Registered fund · May 31, 2026 VANGUARD SCOTTSDALE FUNDS, not summed	122,495	0.20%	+4,493	May 31, 2026	VANGUARD SCOTTSDALE FUNDS, not summed
49	Balyasny Asset Management L.P. 13F CIK 1218710 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	111,103	0.18%	+111,103	Jun 30, 2026	carried, not yet filed for the newest quarter
50	Elmind Capital, LP 13F CIK 2052213 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	107,900	0.17%	-100,000	Jun 30, 2026	carried, not yet filed for the newest quarter

29 more nested rows are not shown here; Every filing lists them all.

Shares are restated onto today's split basis. Change compares each row with the same holder's previous filing in the same source; a dash means there is none to compare. Nested 13D/G, insider and fund rows are not summed, since a 13F report already holds them.

Showing 1–50 of 215 holders

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Key facts CIK 1807120 CUSIP 25056L103 13F (30d) 9 filings 9 filers Visit website Investor relations