AMLX · Amylyx Pharmaceuticals, Inc.
$38.66
-1.00 (-2.52%)
At close · Aug 21
Market Cap
$4.31B
Shares
111.42M
Price & Indicators
20d MA
50d MA
200d MA
Earnings
Filing
Insider
Congress
Investor day
Close$38.66
Open$39.80
Day$38.35–41.14
52W close$8.43–39.66
Avg vol 30d3.1M
Short int13.4M · 12.0% float · 6.8d
Short vol54%
Last earningsAug 6, 2026
DataJan 2022–Aug 2026
Filing10-Q · Aug 6
Up next
Next earnings call
Nov 5, 2026
Est · unconfirmed
· in 11 wks
FQ3-26 quarter ends
~Sep 30, 2026
Est
filed Aug 6, 2026
AI Brief
TL;DR.
Bullish
Bearish
From the call
AI-generated from the earnings call and 8-K · may contain errors · not investment advice
Ask ALVIS about this →Equibles Rating
blended score · not investment adviceOverall
Buy
SellHoldBuy
Technical
Buy
Momentum
Very Strong
Sentiment
Neutral
Fundamentals
Strong
Quant / Vol
Very High
Market backdrop
VIX 15.1 · calm
Equity put/call 0.51
Technical
price trend
50 / 200-day cross
No cross
Price vs 200-day avg
+146%
above
Price vs 50-day avg
+91%
above
RSI (14)
82
overbought
MACD trend
Positive
52-week position
97%
near high
Volume (OBV)
Confirms
volume backs price
Momentum
relative strength
1-month return
+110%
trailing
6-month return
+153%
trailing
YTD return
+220%
this year
Relative strength
+141%
vs S&P · 6-mo
Sentiment
smart money
Trend (MA cross)
No cross
50d $20 › 200d $16 — 50d above 200d
Institutional flow
Accumulating
+19% holders QoQ · +50 funds added
Insider flow
Flat
No net insider activity over 90 days
Short interest
Rising
12.03% of float · ▲ +9.3% MoM · 6.8 days cover
Volume signal
Normal
Volume near normal
Institution breadth
Multi-yr high
206 holders — near 3-yr high, broad support
Squeeze score
91
high risk · 0–100
Fundamentals
Revenue growth
+1613%
Y/Y
EPS growth
+65%
Y/Y
Free cash flow
$-123.5M
Balance sheet
$226.7M
net cash
Quant / Vol
risk profile
Volatility
90%
annualized · 1-yr
Max drawdown
−31%
past year
ATR
6.3%
of price · 14-day
Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.
Guidance & track record
Latest guidance
· from the Earnings Call filed Jun 30, 2023
Gross to net discounts
· going forward
12% – 15%
COGS as a percentage of sales
· going forward
6% – 10%
Prior guidance
period ended
· from the Earnings Call filed Nov 9, 2023
Research and development expenses
· fourth quarter
$35M – $40M
Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.
Technicals
trend & momentum for long-term holders Buy
50 / 200-day cross
No cross
Neutral
Price vs 200-day avg
+146%
Bullish
Price vs 50-day avg
+91%
Bullish
RSI (14)
82
Bearish
MACD trend
Positive
Bullish
52-week position
97%
Bullish
Volume (OBV)
Confirms
Neutral
Market signals — smart money & positioning
Bullish · 2 of 6
Trend (MA cross)
No cross
50d $20 › 200d $16 — 50d above 200d
Institutional flow
Accumulating
+19% holders QoQ · +50 funds added
Insider flow
Flat
No net insider activity over 90 days
Short interest
Rising
12.03% of float · ▲ +9.3% MoM · 6.8 days cover
Volume signal
Normal
Volume near normal
Institution breadth
Multi-yr high
206 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $8
Now $39 · 97%
Range high $40
vs 200-day avg +146%
vs 50-day avg +91%
Illustrative technical + ownership context — a signal mix, not investment advice.
Versus peers
Drug Manufacturers - Specialty & Generic — same industry group| Company | Mkt cap | YTD | Rev growth Y/Y | P/E | Short % shares |
|---|---|---|---|---|---|
|
AMLX
this stock
Amylyx Pharmaceuticals, Inc.
|
$4.31B | +220.0% | +1612.9% | — | 12.0% |
|
JHPCY
Jiangsu Hengrui Pharmaceuticals Co., Ltd./ADR
|
$66.37B | — | — | — | 0.0% |
|
TAK
Takeda Pharmaceutical Co Ltd
|
$58.06B | +16.6% | — | — | 0.1% |
|
GALDY
Galderma Group AG/ADR
|
$49.91B | +3.3% | — | — | 0.0% |
|
HLN
Haleon plc
|
$43.98B | -1.1% | — | — | 0.4% |
Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding
At a glance
key data from every sectionOwnership
Short & Settlement
Smart Money
Financials
Filings
Earnings & Events
Performance
| 5D | 20D | 120D | MTD | YTD | |
|---|---|---|---|---|---|
| AMLX | +78.7% | +110.0% | +152.7% | +90.4% | +220.0% |
| SPY | -1.4% | +3.6% | +11.6% | +2.5% | +12.3% |
| vs SPY | +80.1% | +106.4% | +141.1% | +87.9% | +207.7% |
Key facts
CIK
1658551
CUSIP
03237H101
13F (30d)
196 filings
194 filers
Visit website
Investor relations