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AMLX · Amylyx Pharmaceuticals, Inc.

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$38.66 -1.00 (-2.52%) At close · Aug 21
Market Cap
$4.31B
Shares
111.42M

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$38.66 Open$39.80 Day$38.35–41.14 52W close$8.43–39.66 Avg vol 30d3.1M Short int13.4M · 12.0% float · 6.8d Short vol54% Last earningsAug 6, 2026 DataJan 2022–Aug 2026 Filing10-Q · Aug 6

Up next

Next earnings call
Nov 5, 2026 Est · unconfirmed · in 11 wks
FQ3-26 quarter ends
~Sep 30, 2026 Est
filed Aug 6, 2026

AI Brief

TL;DR.

Bullish
    Bearish

      AI-generated from the earnings call and 8-K · may contain errors · not investment advice

      Ask ALVIS about this →

      Equibles Rating

      blended score · not investment advice
      Overall
      Buy
      SellHoldBuy
      Technical Buy Momentum Very Strong Sentiment Neutral Fundamentals Strong Quant / Vol Very High
      Market backdrop VIX 15.1 · calm Equity put/call 0.51
      Technical
      price trend
      Buy
      50 / 200-day cross No cross
      Price vs 200-day avg +146%
      above
      Price vs 50-day avg +91%
      above
      RSI (14) 82
      overbought
      MACD trend Positive
      52-week position 97%
      near high
      Volume (OBV) Confirms
      volume backs price
      Momentum
      relative strength
      Very Strong
      1-month return +110%
      trailing
      6-month return +153%
      trailing
      YTD return +220%
      this year
      Relative strength +141%
      vs S&P · 6-mo
      Sentiment
      smart money
      Neutral
      Trend (MA cross) No cross
      50d $20 › 200d $16 — 50d above 200d
      Institutional flow Accumulating
      +19% holders QoQ · +50 funds added
      Insider flow Flat
      No net insider activity over 90 days
      Short interest Rising
      12.03% of float · ▲ +9.3% MoM · 6.8 days cover
      Volume signal Normal
      Volume near normal
      Institution breadth Multi-yr high
      206 holders — near 3-yr high, broad support
      Squeeze score 91
      high risk · 0–100
      Fundamentals
      Strong
      Revenue growth +1613%
      Y/Y
      EPS growth +65%
      Y/Y
      Free cash flow $-123.5M
      Balance sheet $226.7M
      net cash
      Quant / Vol
      risk profile
      Very High
      Volatility 90%
      annualized · 1-yr
      Max drawdown −31%
      past year
      ATR 6.3%
      of price · 14-day

      Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

      Guidance & track record

      Latest guidance · from the Earnings Call filed Jun 30, 2023
      Gross to net discounts · going forward 12% – 15%
      COGS as a percentage of sales · going forward 6% – 10%
      Prior guidance period ended · from the Earnings Call filed Nov 9, 2023
      Research and development expenses · fourth quarter $35M – $40M

      Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

      Technicals

      trend & momentum for long-term holders Buy
      1 · 2 · 4
      50 / 200-day cross
      No cross Neutral
      Price vs 200-day avg
      +146% Bullish
      Price vs 50-day avg
      +91% Bullish
      RSI (14)
      82 Bearish
      MACD trend
      Positive Bullish
      52-week position
      97% Bullish
      Volume (OBV)
      Confirms Neutral
      Market signals — smart money & positioning
      Bullish · 2 of 6
      Trend (MA cross) No cross
      50d $20 › 200d $16 — 50d above 200d
      Institutional flow Accumulating
      +19% holders QoQ · +50 funds added
      Insider flow Flat
      No net insider activity over 90 days
      Short interest Rising
      12.03% of float · ▲ +9.3% MoM · 6.8 days cover
      Volume signal Normal
      Volume near normal
      Institution breadth Multi-yr high
      206 holders — near 3-yr high, broad support
      Price context
      position in its 52-week range
      Range low $8 Now $39 · 97% Range high $40
      vs 200-day avg +146% vs 50-day avg +91%

      Illustrative technical + ownership context — a signal mix, not investment advice.

      Versus peers

      Drug Manufacturers - Specialty & Generic — same industry group
      Open screener →
      Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
      AMLX
      Amylyx Pharmaceuticals, Inc.
      this stock
      $4.31B +220.0% +1612.9% 12.0%
      JHPCY
      Jiangsu Hengrui Pharmaceuticals Co., Ltd./ADR
      $66.37B 0.0%
      TAK
      Takeda Pharmaceutical Co Ltd
      $58.06B +16.6% 0.1%
      GALDY
      Galderma Group AG/ADR
      $49.91B +3.3% 0.0%
      HLN
      Haleon plc
      $43.98B -1.1% 0.4%

      Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

      At a glance

      key data from every section
      Ownership
      Institutional Holders Accumulating
      Holders
      206
      % held
      103.7%
      Net QoQ
      +900.3K sh
      Top holder
      FMR LLC
      Held Float
      View
      Held by Funds
      Fund positions
      190
      View
      Short & Settlement
      Short Interest Rising
      Shares short
      13.4M
      Days to cover
      6.8d
      Change
      +1.1M sh
      View
      Short Volume
      Short vol %
      54%
      As of
      Aug 21, 2026
      Short Total
      View
      Fails to Deliver
      FTD shares
      21
      Value
      $409
      As of
      Jul 28, 2026
      View
      Off-Exchange
      Off-exchange %
      44.7%
      Week of
      Jul 13, 2026
      Off-exch Lit
      View
      Smart Money
      Congressional Trades Buy
      Member
      Christopher L. Jacobs
      Amount
      $1.0K–$15.0K
      Traded
      Oct 12, 2022
      View
      Financials
      Financials
      Revenue (FY)
      $0
      Net income (FY)
      $-144.7M
      EPS diluted
      $-1.53
      View
      Filings
      SEC Filings
      Latest
      8-K
      Filed
      Aug 20, 2026
      This year
      13
      View
      Proposed Sales
      Value
      $536.4K
      Shares
      30.0K
      Filed
      Jul 9, 2026
      View
      Exempt Offerings
      Offering
      $30.0M
      Filed
      Jul 1, 2020
      View
      Earnings & Events
      Earnings Calls
      Last call
      Aug 6, 2026
      View

      Performance

      5D 20D 120D MTD YTD
      AMLX +78.7% +110.0% +152.7% +90.4% +220.0%
      SPY -1.4% +3.6% +11.6% +2.5% +12.3%
      vs SPY +80.1% +106.4% +141.1% +87.9% +207.7%
      Key facts CIK 1658551 CUSIP 03237H101 13F (30d) 196 filings 194 filers Visit website Investor relations