Position in ACAD
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$17,254,193
-$12,637,422 QoQ
Shares Held
775,121
-30.7% QoQ
Ownership
0.453%
of shares outstanding
% of Portfolio
0.02%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Jun 2020
20 quarters on record
Voting authority
Sole 99.71617334583891.ToString("F0")%
Shared 0.ToString("F0")%
None 0.28382665416109226.ToString("F0")%
Common Shares in ACAD Over Time
Shares Held
Position Value (USD)
Derivatives in ACAD
reported options exposure · as of Mar 31, 2024CallValue
$554,700
CallShares
30,000
PutValue
$0
PutShares
0
Notional value of option positions as reported on Form 13F. Calls and puts are disclosed separately and do not net against the common-share stake above.
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. ACAD ranks #51 (0.3% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in ACAD
Export CSV
21 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $17,254,193 | 775,121 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $29,891,615 | 1,119,117 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $14,210,113 | 665,891 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $10,420,423 | 483,098 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $13,564,656 | 816,656 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $22,817,160 | 1,243,442 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $17,075,737 | 1,110,256 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $5,650,401 | 347,717 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $2,023,342 | 109,429 | Shares | Sole | 2024-05-15 | |
| 2024-03-31 | $554,700 | 30,000 | Call | Sole | 2024-05-15 | |
| 2023-12-31 | $10,918,673 | 348,728 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $1,460,884 | 70,100 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $8,784,572 | 366,788 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $1,998,684 | 106,200 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $177,301 | 11,137 | Shares | Sole | 2023-02-14 | |
| 2022-06-30 | $828,492 | 58,800 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $5,824,207 | 240,471 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $609,174 | 26,100 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $260,777 | 15,700 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $336,582 | 13,800 | Shares | Sole | 2021-08-16 | |
| 2020-06-30 | $13,892,374 | 286,618 | Shares | Sole | 2020-08-14 | |
| No filing history on record for this holder in this stock. | ||||||