RA CAPITAL MANAGEMENT, L.P.

Position in ACRS — Aclaris Therapeutics, Inc.

CIK 1346824 BOSTON, MA

Position in ACRS

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$25,515,270

+$18,375,270 QoQ

Shares Held

6,804,072

+45.8% QoQ

Ownership

4.87%

of shares outstanding

% of Portfolio

0.27%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2022

9 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

RA CAPITAL MANAGEMENT, L.P. holds $9,134,713,488 across 74 Biotechnology names. ACRS ranks #50 (0.3% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	ASND	Ascendis Pharma A/S	10,281,496	$2,351,686,580
2	PCVX	Vaxcyte, Inc.	11,474,599	$666,788,947
3	RYTM	Rhythm Pharmaceuticals, Inc.	6,666,837	$579,814,813
4	TYRA	Tyra Biosciences, Inc.	12,198,625	$467,207,337
5	SION	Sionna Therapeutics, Inc.	9,905,045	$397,093,254
6	EWTX	Edgewise Therapeutics, Inc.	10,428,437	$328,495,765
7	NAMS	NewAmsterdam Pharma Co N.V.	9,550,191	$305,701,613
8	NUVL	Nuvalent, Inc.	2,534,145	$259,623,155

9 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$25,515,270	6,804,072	+45.8%	Shares	Sole	2026-05-15
2025-03-31	$7,140,000	4,666,667	0.0%	Shares	Sole	2025-05-15
2024-12-31	$11,573,334	4,666,667	+6.1%	Shares	Sole	2025-02-14
2023-06-30	$45,611,957	4,398,453	0.0%	Shares	Sole	2023-08-14
2023-03-31	$35,583,484	4,398,453	0.0%	Shares	Sole	2023-05-15
2022-12-31	$69,275,634	4,398,453	0.0%	Shares	Sole	2023-02-14
2022-09-30	$69,231,650	4,398,453	0.0%	Shares	Sole	2022-11-14
2022-06-30	$61,402,403	4,398,453	+142.0%	Shares	Sole	2022-08-15
2022-03-31	$31,339,009	1,817,808	—	Shares	Sole	2022-05-16
No filing history on record for this holder in this stock.