Position in ALT
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$7,238,671
-$396,341 QoQ
Shares Held
2,381,142
-3.9% QoQ
Ownership
1.22%
of shares outstanding
% of Portfolio
0.01%
of 13F equity value
Holder Rank
#15
of 210 holders
Holding Since
Jun 2020
21 quarters on record
Voting authority
Sole 99%
Shared 0%
None 1%
Common Shares in ALT Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,283,390,440 across 343 Biotechnology names. ALT ranks #98 (0.1% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in ALT
Export CSV
21 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $7,238,671 | 2,381,142 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $7,635,012 | 2,478,900 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $4,569,115 | 1,265,683 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $7,528,116 | 1,996,848 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,692,296 | 437,286 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $5,739,080 | 1,147,816 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $4,364,234 | 605,303 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $2,789,414 | 454,302 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $3,834,163 | 576,566 | Shares | Sole | 2024-08-14 | |
| 2023-09-30 | $1,735,292 | 667,420 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $3,483,474 | 986,820 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $4,406,469 | 1,044,187 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $12,770,085 | 776,297 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $12,484,552 | 977,647 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $7,202,730 | 615,618 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $3,680,917 | 604,420 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $5,280,025 | 576,422 | Shares | Sole | 2022-02-14 | |
| 2021-03-31 | $373,017 | 26,399 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $460,810 | 40,852 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $8,608,617 | 652,168 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $170,278 | 15,899 | Shares | Sole | 2020-08-14 | |
| No filing history on record for this holder in this stock. | ||||||