TWO SIGMA INVESTMENTS, LP

Position in ANIK — Anika Therapeutics, Inc.

CIK 1179392 NEW YORK, NY

Position in ANIK

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$3,423,740

+$1,176,846 QoQ

Shares Held

236,120

+1.0% QoQ

Ownership

1.77%

of shares outstanding

% of Portfolio

0.00%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Mar 2020

23 quarters on record

Voting authority Sole 98% Shared 0% None 2%

Healthcare · as of Mar 31, 2026

TWO SIGMA INVESTMENTS, LP holds $750,878,580 across 46 Drug Manufacturers - Specialty & Generic names. ANIK ranks #22 (0.5% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	NBIX	Neurocrine Biosciences Inc	3,060,570	$403,199,491
2	BCRX	Biocryst Pharmaceuticals Inc	6,392,628	$60,857,818
3	ALKS	Alkermes plc.	780,683	$27,604,950
4	ESPR	Esperion Therapeutics, Inc.	9,458,779	$25,917,054
5	LQDA	Liquidia Corp	563,233	$21,256,413
6	IRWD	Ironwood Pharmaceuticals Inc	5,848,276	$20,527,448
7	KNSA	Kiniksa Pharmaceuticals International, plc	420,914	$20,267,009
8	COLL	Collegium Pharmaceutical, Inc	590,116	$19,515,136

23 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$3,423,740	236,120	+1.0%	Shares	Sole	2026-05-15
2025-12-31	$2,246,894	233,808	+192.5%	Shares	Sole	2026-02-17
2025-09-30	$751,257	79,921	+560.7%	Shares	Sole	2025-11-14
2024-12-31	$199,100	12,096	-43.3%	Shares	Sole	2025-02-14
2024-09-30	$526,999	21,336	-24.1%	Shares	Sole	2024-11-14
2024-06-30	$711,773	28,100	-40.6%	Shares	Sole	2024-08-14
2024-03-31	$1,200,658	47,270	-21.6%	Shares	Sole	2024-05-15
2023-12-31	$1,365,582	60,264	+242.1%	Shares	Sole	2024-02-14
2023-09-30	$328,148	17,614	-72.7%	Shares	Sole	2023-11-14
2023-06-30	$1,677,009	64,550	+33.4%	Shares	Sole	2023-08-14
2023-03-31	$1,390,191	48,405	-22.7%	Shares	Sole	2023-05-15
2022-12-31	$1,853,907	62,632	+91.2%	Shares	Sole	2023-02-14
2022-09-30	$779,521	32,753	-49.9%	Shares	Sole	2022-11-14
2022-06-30	$1,458,969	65,366	+35.4%	Shares	Sole	2022-08-15
2022-03-31	$1,212,235	48,277	-10.0%	Shares	Sole	2022-05-16
2021-12-31	$1,922,458	53,655	-18.2%	Shares	Sole	2022-02-14
2021-09-30	$2,790,574	65,568	-43.4%	Shares	Sole	2021-11-15
2021-06-30	$5,018,393	115,925	+2.8%	Shares	Sole	2021-08-16
2021-03-31	$4,600,418	112,783	+115.9%	Shares	Sole	2021-05-17
2020-12-31	$2,364,110	52,234	+15.7%	Shares	Sole	2021-02-16
2020-09-30	$1,597,929	45,152	+64.0%	Shares	Sole	2020-11-16
2020-06-30	$1,038,857	27,534	-2.0%	Shares	Sole	2020-08-14
2020-03-31	$811,850	28,082	—	Shares	Sole	2020-05-15
No filing history on record for this holder in this stock.