TWO SIGMA INVESTMENTS, LP
Position in CRNX — Crinetics Pharmaceuticals, Inc.
CIK 1179392
NEW YORK, NY
Position in CRNX
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$3,266,728
+$96,029 QoQ
Shares Held
87,299
0.0% QoQ
Ownership
0.082%
of shares outstanding
% of Portfolio
0.00%
of 13F equity value
Holder Rank
#82
of 266 holders
Holding Since
Jun 2020
23 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in CRNX Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026TWO SIGMA INVESTMENTS, LP holds $7,273,657,992 across 342 Biotechnology names. CRNX ranks #135 (0.0% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,875,937 | $564,713,315 | |
| 2 | MRNA |
Moderna, Inc.
|
7,193,530 | $503,762,905 | |
| 3 | IONS |
Ionis Pharmaceuticals Inc
|
6,252,342 | $495,748,197 | |
| 4 | REGN |
Regeneron Pharmaceuticals, Inc.
|
656,124 | $409,119,558 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
4,722,185 | $351,708,338 | |
| 6 | EXEL |
Exelixis, Inc.
|
4,209,861 | $229,058,537 | |
| 7 | INCY |
Incyte Corp
|
2,003,559 | $227,123,448 | |
| 8 | ARGX |
Argenx SE
|
185,638 | $172,229,367 |
All Filings in CRNX
Export CSV
23 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $3,266,728 | 87,299 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $3,170,699 | 87,299 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $2,313,488 | 49,699 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $2,069,963 | 49,699 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,517,924 | 52,779 | Shares | Sole | 2025-08-14 | |
| 2024-09-30 | $276,655 | 5,414 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $483,732 | 10,800 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $5,564,772 | 118,880 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $6,870,533 | 193,101 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $11,954,082 | 401,953 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $1,649,460 | 91,535 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $517,132 | 32,200 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $450,399 | 24,612 | Shares | Sole | 2023-02-14 | |
| 2022-09-30 | $456,747 | 23,256 | Shares | Sole | 2022-11-14 | |
| 2022-06-30 | $871,794 | 46,745 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $2,651,055 | 120,777 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $3,900,465 | 137,292 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $3,079,446 | 146,292 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $2,192,443 | 116,310 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $885,384 | 57,944 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $760,684 | 53,911 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $424,296 | 27,077 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $942,786 | 53,812 | Shares | Sole | 2020-08-14 | |
| No filing history on record for this holder in this stock. | ||||||