HLXC · Helix Acquisition Corp. III · Insider Trading

This form amends a Form 4 previously filed for the Reporting Person on January 26, 2026 to correct the number of shares that should have been reported on such date, which now includes shares purchased by Cormorant Global Healthcare Master Fund, LP in the Issuer's initial public offering, as described in further detail in the Issuer's registration statement on Form S-1 (File No. 333-291933) ("Registration Statement").

Cormorant Global Healthcare Master Fund, LP is the record holder of such securities. Ms. Chen is the managing member of Cormorant Global Healthcare Master Fund, LP and has voting and investment discretion with respect to the ordinary shares of record held thereby. Ms. Chen disclaims any beneficial ownership of the securities held by Cormorant Global Healthcare Master Fund, LP other than to the extent of any pecuniary interest she may have therein, directly or indirectly.

Helix Holdings III LLC is the record holder of the securities reported herein. Cormorant Private Healthcare Fund VI, LP ("Cormorant Fund VI") and Cormorant Global Healthcare Master Fund, LP, together own 100% of the membership interests in Helix Holdings III LLC. Bihua Chen is the managing member of each of Cormorant Fund VI and Cormorant Global Healthcare Master Fund, LP and has voting and investment discretion with respect to the ordinary shares held of record by Helix Holdings III LLC. Bihua Chen disclaims any beneficial ownership of the securities held by Helix Holdings III LLC other than to the extent of any pecuniary interest she may have therein, directly or indirectly.

As described in the Registration Statement, under the heading "Description of Securities--Founder Shares and Private Placement Shares", the terms of the Class B ordinary shares, par value $0.0001 per share, provided at issuance that they would automatically convert into Class A ordinary shares, par value $0.0001 per share, concurrently with or immediately following the consummation of the Issuer's initial business combination or earlier at the option of the holder on a one-for-one basis, subject to adjustment for share sub-divisions, share capitalizations, reorganizations, recapitalizations and the like, and certain anti-dilution rights and have no expiration date.

On January 22, 2026, the Issuer effected a share capitalization with respect to the Class B ordinary shares, resulting in the issue and allotment of 718,750 Class B ordinary shares to Helix Holdings III LLC.

Helix Holdings III LLC is the record holder of the securities reported herein. Cormorant Private Healthcare Fund VI, LP ("Cormorant Fund VI") and Cormorant Global Healthcare Master Fund, LP, together own 100% of the membership interests in Helix Holdings III LLC. Bihua Chen is the managing member of each of Cormorant Fund VI and Cormorant Global Healthcare Master Fund, LP and has voting and investment discretion with respect to the ordinary shares held of record by Helix Holdings III LLC. Bihua Chen disclaims any beneficial ownership of the securities held by Helix Holdings III LLC other than to the extent of any pecuniary interest she may have therein, directly or indirectly.