Position in INVA
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$34,583,351
+$17,794,450 QoQ
Shares Held
1,484,264
+76.7% QoQ
Ownership
2.01%
of shares outstanding
% of Portfolio
0.03%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
21 quarters on record
Voting authority
Sole 99.17804379813833.ToString("F0")%
Shared 0.ToString("F0")%
None 0.8219562018616634.ToString("F0")%
Common Shares in INVA Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. INVA ranks #33 (0.6% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in INVA
Export CSV
21 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $34,583,351 | 1,484,264 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $16,788,901 | 839,865 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $9,530,916 | 522,242 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $6,667,589 | 331,886 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $12,103,316 | 667,585 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $4,558,521 | 262,739 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $9,342,409 | 483,812 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $8,851,473 | 539,724 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $8,370,204 | 549,226 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $5,949,460 | 370,914 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $3,748,212 | 288,546 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $4,676,085 | 367,328 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $200,148 | 17,791 | Shares | Sole | 2023-05-15 | |
| 2022-12-31 | $2,350,364 | 177,386 | Shares | Sole | 2023-02-14 | |
| 2022-06-30 | $6,115,525 | 414,331 | Shares | Sole | 2022-08-15 | |
| 2022-03-31 | $15,758,698 | 814,403 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $7,106,620 | 411,978 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $5,039,769 | 301,602 | Shares | Sole | 2021-11-15 | |
| 2020-09-30 | $326,802 | 31,273 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $1,030,339 | 73,701 | Shares | Sole | 2020-08-14 | |
| 2020-03-31 | $1,103,123 | 93,803 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||