ADAGE CAPITAL PARTNERS GP, L.L.C.
Position in KPTI — Karyopharm Therapeutics Inc.
CIK 1165408
Boston, MA
Position in KPTI
as of Jun 30, 2026
· filed Aug 14, 2026
Position Value
$14,863,315
+$4,802,102 QoQ
Shares Held
1,521,322
-15.8% QoQ
Ownership
6.71%
of shares outstanding
% of Portfolio
0.02%
of 13F equity value
Holder Rank
#2
of 96 holders
Holding Since
Mar 2020
17 quarters on record
Voting authority
Sole 100%
Shared 0%
None 0%
Common Shares in KPTI Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Jun 30, 2026ADAGE CAPITAL PARTNERS GP, L.L.C. holds $4,240,035,723 across 125 Biotechnology names. KPTI ranks #67 (0.4% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ROIV |
Roivant Sciences Ltd.
|
10,349,328 | $366,262,717 | |
| 2 | PRAX |
Praxis Precision Medicines, Inc.
|
1,015,480 | $339,972,549 | |
| 3 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
393,964 | $195,693,737 | |
| 4 | TNGX |
Tango Therapeutics, Inc.
|
5,600,000 | $175,056,000 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
2,252,000 | $167,728,960 | |
| 6 | SYRE |
Spyre Therapeutics, Inc.
|
1,722,300 | $152,905,794 | |
| 7 | TVTX |
Travere Therapeutics, Inc.
|
2,569,356 | $145,965,114 | |
| 8 | RPRX |
Royalty Pharma plc
|
2,500,000 | $140,175,000 |
All Filings in KPTI
Export CSV
17 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-06-30 | $14,863,315 | 1,521,322 | Shares | Sole | 2026-08-14 | |
| 2026-03-31 | $10,061,213 | 1,806,322 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $3,100,929 | 421,322 | Shares | Sole | 2026-02-17 | |
| 2025-09-30 | $2,755,445 | 421,322 | Shares | Sole | 2025-11-14 | |
| 2025-06-30 | $1,815,897 | 421,322 | Shares | Sole | 2025-08-14 | |
| 2025-03-31 | $1,575,744 | 421,322 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $4,272,213 | 6,319,842 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $3,585,468 | 4,319,842 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $3,749,622 | 4,319,842 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $5,285,000 | 3,500,000 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $1,438,754 | 1,663,300 | Shares | Sole | 2024-02-14 | |
| 2022-12-31 | $2,620,424 | 770,713 | Shares | Sole | 2023-02-14 | |
| 2021-03-31 | $14,199,896 | 1,349,800 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $38,158,200 | 2,465,000 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $46,908,792 | 3,212,931 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $61,531,116 | 3,248,739 | Shares | Sole | 2020-08-14 | |
| 2020-03-31 | $71,529,049 | 3,723,532 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||