LIPO · Lipella Pharmaceuticals Inc.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") were subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person had voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA").

Upon the effectiveness of a registration statement registering the Warrant Shares and Conversion Shares as of April 3, 2025, such voting power granted to the reporting person over the Securities by Spartan and such Affiliates was terminated. Please see the Proxy and POA attached as Exhibit 24 to the Form 4 filed by the reporting person with the U.S. Securities and Exchange Commission on March 17, 2025.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") were subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person had voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA").

Upon the effectiveness of a registration statement registering the Warrant Shares and Conversion Shares as of April 3, 2025, such voting power granted to the reporting person over the Securities by Spartan and such Affiliates was terminated. Please see the Proxy and POA attached as Exhibit 24 to the Form 4 filed by the reporting person with the U.S. Securities and Exchange Commission on March 17, 2025.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") were subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person had voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA").

Upon the effectiveness of a registration statement registering the Warrant Shares and Conversion Shares as of April 3, 2025, such voting power granted to the reporting person over the Securities by Spartan and such Affiliates was terminated. Please see the Proxy and POA attached as Exhibit 24 to the Form 4 filed by the reporting person with the U.S. Securities and Exchange Commission on March 17, 2025.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") were subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person had voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA").

Upon the effectiveness of a registration statement registering the Warrant Shares and Conversion Shares as of April 3, 2025, such voting power granted to the reporting person over the Securities by Spartan and such Affiliates was terminated. Please see the Proxy and POA attached as Exhibit 24 to the Form 4 filed by the reporting person with the U.S. Securities and Exchange Commission on March 17, 2025.

The conversion rights of the Preferred Stock do not expire.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), common stock purchase warrants ("Warrants"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of Warrants (the "Warrant Shares", and collectively with the Preferred Stock, Warrants and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

The conversion rights of the Preferred Stock do not expire.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), common stock purchase warrants ("Warrants"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of Warrants (the "Warrant Shares", and collectively with the Preferred Stock, Warrants and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), common stock purchase warrants ("Warrants"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of Warrants (the "Warrant Shares", and collectively with the Preferred Stock, Warrants and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), common stock purchase warrants ("Warrants"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of Warrants (the "Warrant Shares", and collectively with the Preferred Stock, Warrants and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

The conversion rights of the Preferred Stock do not expire.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), common stock purchase warrants ("Warrants"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of Warrants (the "Warrant Shares", and collectively with the Preferred Stock, Warrants and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

The conversion rights of the Preferred Stock do not expire.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), common stock purchase warrants ("Warrants"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of Warrants (the "Warrant Shares", and collectively with the Preferred Stock, Warrants and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") were subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person had voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA").

Upon the effectiveness of a registration statement registering the Securities as of January 15, 2025, such voting power granted to the reporting person by Spartan and such Affiliates was terminated. Please see the Proxy and POA attached as Exhibit 24 to the Form 4 filed by the reporting person with the U.S. Securities and Exchange Commission on January 3, 2025.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") were subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person had voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA").

Upon the effectiveness of a registration statement registering the Securities as of January 15, 2025, such voting power granted to the reporting person by Spartan and such Affiliates was terminated. Please see the Proxy and POA attached as Exhibit 24 to the Form 4 filed by the reporting person with the U.S. Securities and Exchange Commission on January 3, 2025.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") were subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person had voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA").

Upon the effectiveness of a registration statement registering the Securities as of January 15, 2025, such voting power granted to the reporting person by Spartan and such Affiliates was terminated. Please see the Proxy and POA attached as Exhibit 24 to the Form 4 filed by the reporting person with the U.S. Securities and Exchange Commission on January 3, 2025.

The conversion rights of the Preferred Stock do not expire.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities and such warrants except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

The conversion rights of the Preferred Stock do not expire.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of the Common Stock purchase warrants (the "Warrant Shares", and collectively with the Preferred Stock and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities and such warrants except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), common stock purchase warrants ("Warrants"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of Warrants (the "Warrant Shares", and collectively with the Preferred Stock, Warrants and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

The conversion rights of the Preferred Stock do not expire.

Such Series C Voting Convertible Preferred Stock, par value $0.0001 per share ("Preferred Stock"), common stock purchase warrants ("Warrants"), and the common stock, par value $0.0001 per share, of the issuer ("Common Stock"), issuable upon conversion of Preferred Stock ("Conversion Shares") and exercise of Warrants (the "Warrant Shares", and collectively with the Preferred Stock, Warrants and Conversion Shares, "Securities") are subject to an irrevocable proxy and power of attorney, effective December 20, 2024, between the reporting person and Spartan Capital Securities, LLC ("Spartan"), pursuant to which the reporting person has voting power over all Securities held by Spartan and its Affiliates (defined under Rule 405 of the Securities Act of 1933, as amended) or any person or entity acting as a group therewith ("Proxy and POA"). The reporting person disclaims beneficial ownership of the Securities except to the extent of his pecuniary interest therein, if any.

Each share of Preferred Stock is convertible into shares of Common Stock on or after the date on which the registration statement filed by the issuer registering the reoffer and resale of the Conversion Shares has been declared effective by the U.S. Securities Exchange Commission.

Open market purchase by the reporting person of 10,000 shares of common stock, par value $0.0001 per share (the "Common Stock").

Reflects the weighted average price of the shares of Common Stock purchased on the open market in multiple transactions on May 14, 2024 at prices ranging from $0.7552 to $0.76 per share, inclusive. The amount reflected has been rounded to 3 decimal points.

The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of such shares of Common Stock purchased at each separate price within such range.

Open market purchase by the reporting person of 25,000 shares of Common Stock.

The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of such shares of Common Stock purchased at each separate price within such range.

Reflects the weighted average price of the shares of Common Stock purchased on the open market in multiple transactions on March 19, 2024 at prices ranging from $0.75 to $0.89 per share, inclusive.

Open market purchase by the reporting person of 30,000 shares of common stock, par value $0.0001 per share (the "Common Stock").

Reflects the weighted average price of the shares purchased on the open market in multiple transactions on March 18, 2024 at prices ranging from $0.77 to $0.80 per share, inclusive.

The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the U.S. Securities and Exchange Commission, upon request, full information regarding the number of such shares of Common Stock purchased at each separate price within such range.

The number of shares of Common Stock has been increased by two from the number of shares reported as directly owned in the Form 4 filed by the reporting person on June 21, 2023 in order to correct an inadvertent administrative error in such prior Form 4.

The number of shares of Common Stock has been increased by one from the number of shares reported as directly owned in the Form 4 filed by the reporting person on December 27, 2022 in order to correct an inadvertent administrative error in such prior Form 4.

The Reporting Person received 22,950 shares of common stock, par value $0.0001 per share, upon the cancellation of promissory notes of the Issuer held by the Reporting Person.