Opaleye Management Inc.

CIK
0001595855
City
Boston
State / Country
MA

Top Portfolio Positions

46 positions · $726,537,966 total · as of Dec 31, 2025
Ticker Company Shares Value (USD) % of Portfolio
HROW
Harrow, Inc.
3,905,000 $191,345,000 26.34%
LQDA
Liquidia Corp
2,435,000 $83,983,150 11.56%
ETON
Eton Pharmaceuticals, Inc.
2,860,000 $48,362,600 6.66%
RYTM
Rhythm Pharmaceuticals, Inc.
330,000 $35,323,200 4.86%
APGE
Apogee Therapeutics, Inc.
388,257 $29,305,638 4.03%
SNWV
SANUWAVE Health, Inc.
981,267 $29,281,007 4.03%
STOK
Stoke Therapeutics, Inc.
695,000 $22,059,300 3.04%
OCUL
Ocular Therapeutix, Inc
1,595,000 $19,363,300 2.67%
SLGL
Sol-Gel Technologies Ltd.
453,739 $19,120,561 2.63%
CGON
CG Oncology, Inc.
410,000 $17,023,200 2.34%

Portfolio Trend

24 quarters · across all stocks

Holdings in LQDA

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Shares Held

Position Value (USD)

18 of 18 shown
Report Date Value (USD) Shares
2025-12-31 $83,983,150 2,435,000
2025-09-30 $59,465,100 2,615,000
2025-06-30 $30,838,500 2,475,000
2025-03-31 $33,335,000 2,260,000
2024-12-31 $19,970,149 1,698,142
2024-09-30 $16,981,420 1,698,142
2024-06-30 $3,900,000 325,000
2024-03-31 $5,826,250 395,000
2023-12-31 $5,353,350 445,000
2023-09-30 $3,618,238 570,700
2023-06-30 $4,479,995 570,700
2023-03-31 $3,974,632 575,200
2022-12-31 $3,567,200 560,000
2022-09-30 $3,065,440 563,500
2022-06-30 $2,273,740 521,500
2022-03-31 $1,283,784 178,800
2021-12-31 $81,816 16,800
2020-06-30 $3,368,000 400,000