ADAGE CAPITAL PARTNERS GP, L.L.C.

Position in RARE — Ultragenyx Pharmaceutical Inc.

CIK 1165408 Boston, MA

Position in RARE

as of Mar 31, 2026 · filed May 15, 2026 Compact

Position Value

$10,056,000

+$3,616,000 QoQ

Shares Held

480,000

+71.4% QoQ

Ownership

0.487%

of shares outstanding

% of Portfolio

0.02%

of 13F equity value

Holder Rank

—

not a current holder

Holding Since

Dec 2020

22 quarters on record

Voting authority Sole 100.ToString("F0")% Shared 0.ToString("F0")% None 0.ToString("F0")%

Healthcare · as of Mar 31, 2026

ADAGE CAPITAL PARTNERS GP, L.L.C. holds $4,593,636,445 across 120 Biotechnology names. RARE ranks #69 (0.2% of the industry book) .

#	Ticker	Company	Shares	Value (USD)
1	RVMD	Revolution Medicines, Inc.	5,475,611	$532,503,169
2	RPRX	Royalty Pharma plc	7,480,633	$358,845,965
3	CNTA	Centessa Pharmaceuticals plc	8,925,010	$354,501,397
4	ROIV	Roivant Sciences Ltd.	12,794,097	$354,396,486
5	TNGX	Tango Therapeutics, Inc.	12,809,485	$267,974,426
6	PRAX	Praxis Precision Medicines, Inc.	815,739	$262,822,948
7	INSM	INSMED Inc	900,000	$147,168,000
8	AXSM	Axsome Therapeutics, Inc.	737,578	$124,665,433

22 filing rows on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2026-03-31	$10,056,000	480,000	+71.4%	Shares	Sole	2026-05-15
2025-12-31	$6,440,000	280,000	-34.9%	Shares	Sole	2026-02-17
2025-09-30	$12,934,400	430,000	-71.9%	Shares	Sole	2025-11-14
2025-06-30	$55,611,674	1,529,474	-28.8%	Shares	Sole	2025-08-14
2025-03-31	$77,815,290	2,149,000	+81.6%	Shares	Sole	2025-05-15
2024-12-31	$49,772,217	1,183,081	-22.5%	Shares	Sole	2025-02-14
2024-09-30	$84,754,912	1,525,741	+35.6%	Shares	Sole	2024-11-14
2024-06-30	$46,237,500	1,125,000	+650.0%	Shares	Sole	2024-08-14
2024-03-31	$7,003,500	150,000	-85.4%	Shares	Sole	2024-05-15
2023-12-31	$49,015,500	1,025,000	+1038.9%	Shares	Sole	2024-02-14
2023-09-30	$3,208,500	90,000	-16.4%	Shares	Sole	2023-11-14
2023-06-30	$4,963,588	107,600	-11.8%	Shares	Other	2023-08-14
2023-03-31	$4,892,200	122,000	-12.9%	Shares	Sole	2023-05-15
2022-12-31	$6,486,200	140,000	-9.7%	Shares	Sole	2023-02-14
2022-09-30	$6,421,117	155,062	-77.2%	Shares	Sole	2022-11-14
2022-06-30	$40,568,800	680,000	-2.9%	Shares	Sole	2022-08-15
2022-03-31	$50,834,000	700,000	0.0%	Shares	Sole	2022-05-16
2021-12-31	$58,863,000	700,000	+12.9%	Shares	Sole	2022-02-14
2021-09-30	$55,917,800	620,000	+138.5%	Shares	Sole	2021-11-15
2021-06-30	$24,791,000	260,000	+40.5%	Shares	Sole	2021-08-16
2021-03-31	$21,064,100	185,000	+11.8%	Shares	Sole	2021-05-17
2020-12-31	$22,910,165	165,500	—	Shares	Sole	2021-02-16
No filing history on record for this holder in this stock.