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TWO SIGMA INVESTMENTS, LP

Position in XENE — Xenon Pharmaceuticals Inc.

CIK 1179392 NEW YORK, NY

Position in XENE

as of Jun 30, 2026 · filed Aug 14, 2026
Position Value
$99,162,305
+$63,918,463 QoQ
Shares Held
1,642,848
+171.1% QoQ
Ownership
1.70%
of shares outstanding
% of Portfolio
0.08%
of 13F equity value
Holder Rank
#12
of 314 holders
Holding Since
Mar 2020
22 quarters on record
Voting authority Sole 99% Shared 0% None 1%

Common Shares in XENE Over Time

Shares Held

Position Value (USD)

Position in Biotechnology

Healthcare · as of Jun 30, 2026

TWO SIGMA INVESTMENTS, LP holds $7,273,657,992 across 342 Biotechnology names. XENE ranks #19 (1.4% of the industry book) .

# Ticker Company Shares Value (USD) Open

All Filings in XENE

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22 filing rows on record
Report Date Value (USD) Shares
2026-06-30 $99,162,305 1,642,848
2026-03-31 $35,243,842 606,085
2025-12-31 $19,574,821 436,743
2025-03-31 $7,950,779 236,983
2024-12-31 $10,715,398 273,352
2024-09-30 $9,589,705 243,579
2024-06-30 $7,608,079 195,129
2024-03-31 $11,822,649 274,626
2023-12-31 $15,661,090 340,015
2023-09-30 $2,754,423 80,633
2023-06-30 $717,370 18,633
2023-03-31 $409,938 11,454
2022-09-30 $2,020,661 55,974
2022-03-31 $7,112,110 232,650
2021-12-31 $8,695,435 278,343
2021-09-30 $2,592,649 169,676
2021-06-30 $1,586,759 85,218
2021-03-31 $1,373,037 76,706
2020-12-31 $777,628 50,561
2020-09-30 $553,333 49,985
2020-06-30 $1,506,242 120,115
2020-03-31 $1,004,780 88,605