Position in XENE
as of Mar 31, 2026
· filed May 15, 2026
Position Value
$35,243,842
+$15,669,021 QoQ
Shares Held
606,085
+38.8% QoQ
Ownership
0.627%
of shares outstanding
% of Portfolio
0.03%
of 13F equity value
Holder Rank
—
not a current holder
Holding Since
Mar 2020
21 quarters on record
Voting authority
Sole 98.25107039441663.ToString("F0")%
Shared 0.ToString("F0")%
None 1.7489296055833752.ToString("F0")%
Common Shares in XENE Over Time
Shares Held
Position Value (USD)
Position in Biotechnology
Healthcare · as of Mar 31, 2026TWO SIGMA INVESTMENTS, LP holds $5,506,832,621 across 316 Biotechnology names. XENE ranks #32 (0.6% of the industry book) .
| # | Ticker | Company | Shares | Value (USD) | Open |
|---|---|---|---|---|---|
| 1 | ALNY |
Alnylam Pharmaceuticals, Inc.
|
1,992,577 | $659,283,951 | |
| 2 | REGN |
Regeneron Pharmaceuticals, Inc.
|
812,236 | $627,566,023 | |
| 3 | MRNA |
Moderna, Inc.
|
9,086,404 | $461,589,323 | |
| 4 | IONS |
Ionis Pharmaceuticals Inc
|
5,857,629 | $439,849,361 | |
| 5 | BBIO |
BridgeBio Pharma, Inc.
|
3,120,631 | $231,738,058 | |
| 6 | VRTX |
Vertex Pharmaceuticals Inc / Ma
|
378,146 | $168,857,314 | |
| 7 | RVMD |
Revolution Medicines, Inc.
|
1,558,807 | $151,593,980 | |
| 8 | VKTX |
Viking Therapeutics, Inc.
|
4,432,142 | $144,221,900 |
All Filings in XENE
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21 filing rows on record
| Report Date | Value (USD) | Shares | Type | Discretion | Filed | |
|---|---|---|---|---|---|---|
| 2026-03-31 | $35,243,842 | 606,085 | Shares | Sole | 2026-05-15 | |
| 2025-12-31 | $19,574,821 | 436,743 | Shares | Sole | 2026-02-17 | |
| 2025-03-31 | $7,950,779 | 236,983 | Shares | Sole | 2025-05-15 | |
| 2024-12-31 | $10,715,398 | 273,352 | Shares | Sole | 2025-02-14 | |
| 2024-09-30 | $9,589,705 | 243,579 | Shares | Sole | 2024-11-14 | |
| 2024-06-30 | $7,608,079 | 195,129 | Shares | Sole | 2024-08-14 | |
| 2024-03-31 | $11,822,649 | 274,626 | Shares | Sole | 2024-05-15 | |
| 2023-12-31 | $15,661,090 | 340,015 | Shares | Sole | 2024-02-14 | |
| 2023-09-30 | $2,754,423 | 80,633 | Shares | Sole | 2023-11-14 | |
| 2023-06-30 | $717,370 | 18,633 | Shares | Sole | 2023-08-14 | |
| 2023-03-31 | $409,938 | 11,454 | Shares | Sole | 2023-05-15 | |
| 2022-09-30 | $2,020,661 | 55,974 | Shares | Sole | 2022-11-14 | |
| 2022-03-31 | $7,112,110 | 232,650 | Shares | Sole | 2022-05-16 | |
| 2021-12-31 | $8,695,435 | 278,343 | Shares | Sole | 2022-02-14 | |
| 2021-09-30 | $2,592,649 | 169,676 | Shares | Sole | 2021-11-15 | |
| 2021-06-30 | $1,586,759 | 85,218 | Shares | Sole | 2021-08-16 | |
| 2021-03-31 | $1,373,037 | 76,706 | Shares | Sole | 2021-05-17 | |
| 2020-12-31 | $777,628 | 50,561 | Shares | Sole | 2021-02-16 | |
| 2020-09-30 | $553,333 | 49,985 | Shares | Sole | 2020-11-16 | |
| 2020-06-30 | $1,506,242 | 120,115 | Shares | Sole | 2020-08-14 | |
| 2020-03-31 | $1,004,780 | 88,605 | Shares | Sole | 2020-05-15 | |
| No filing history on record for this holder in this stock. | ||||||