CareDx, Inc S-3ASR, filed Apr 28, 2026

CareDx, Inc. (CDNA)

S-3ASR 2026-04-28

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Added on October 18, 2026

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	Large accelerated filer ☒			Accelerated filer ☐
	Non-accelerated filer ☐			Smaller reporting company ☐
				Emerging growth company ☐

	Page
ABOUT THIS PROSPECTUS		1
PROSPECTUS SUMMARY		3
RISK FACTORS		5
DISCLOSURE REGARDING FORWARD-LOOKING STATEMENTS		6
USE OF PROCEEDS		8
DESCRIPTION OF CAPITAL STOCK		9
DESCRIPTION OF DEBT SECURITIES		14
DESCRIPTION OF WARRANTS		21
DESCRIPTION OF SUBSCRIPTION RIGHTS		23
DESCRIPTION OF UNITS		24
PLAN OF DISTRIBUTION		25
LEGAL MATTERS		28
EXPERTS		29
WHERE YOU CAN FIND MORE INFORMATION		30
IMPORTANT INFORMATION INCORPORATED BY REFERENCE		31

SEC registration fee	$	(1)
Transfer agent’s fees and expenses	$	(2)
Legal fees and expenses	$	(2)
Accounting fees and expenses	$	(2)
Trustee fees and expenses	$	(2)
Printing fees and expenses	$	(2)
Miscellaneous fees and expenses	$	(2)
Total	$	(2)

Signature	Title	Date
/s/ John W. Hanna John W. Hanna	President, Chief Executive Officer and Director (Principal Executive Officer)	April 28, 2026
/s/ Keith Kennedy Keith Kennedy	Chief Operating Officer and Chief Financial Officer (Principal Financial and Accounting Officer)	April 28, 2026
/s/ George W. Bickerstaff, III George W. Bickerstaff, III	Director	April 28, 2026
/s/ Fred E. Cohen, M.D. Fred E. Cohen, M.D.	Director	April 28, 2026
/s/ Christine M. Cournoyer Christine M. Cournoyer	Director	April 28, 2026
/s/ Michael D. Goldberg Michael D. Goldberg	Director	April 28, 2026
/s/ Suresh Gunasekaran Suresh Gunasekaran	Director	April 28, 2026
/s/ Peter Maag, Ph.D. Peter Maag, Ph.D.	Director	April 28, 2026
/s/ Bryan Riggsbee Bryan Riggsbee	Director	April 28, 2026
/s/ Arthur Torres Arthur Torres	Director	April 28, 2026
/s/ Hannah Valantine Hannah Valantine	Director	April 28, 2026


ARTICLE 1 – DEFINITIONS AND INCORPORATION BY REFERENCE	1
1.1 DEFINITIONS	1
1.2. OTHER DEFINITIONS	4
1.3. INCORPORATION BY REFERENCE OF TRUST INDENTURE ACT	4
1.4. RULES OF CONSTRUCTION	4
ARTICLE 2 – THE SECURITIES	5
2.1. ISSUABLE IN SERIES	5
2.2. ESTABLISHMENT OF TERMS OF SERIES OF SECURITIES	5
2.3. EXECUTION AND AUTHENTICATION	6
2.4. REGISTRAR AND PAYING AGENT	7
2.5. PAYING AGENT TO HOLD ASSETS IN TRUST	7
2.6. SECURITYHOLDER LISTS	8
2.7. TRANSFER AND EXCHANGE	8
2.8. REPLACEMENT SECURITIES	8
2.9. OUTSTANDING SECURITIES	8
2.10. WHEN TREASURY SECURITIES DISREGARDED; DETERMINATION OF HOLDERS’ ACTION	9
2.11. TEMPORARY SECURITIES	9
2.12. CANCELLATION	9
2.13. PAYMENT OF INTEREST; DEFAULTED INTEREST; COMPUTATION OF INTEREST	9
2.14. CUSIP NUMBER	10
2.15. PROVISIONS FOR GLOBAL SECURITIES	10
2.16. PERSONS DEEMED OWNERS	11
ARTICLE 3 – REDEMPTION	11
3.1. NOTICES TO TRUSTEE	11
3.2. SELECTION BY TRUSTEE OF SECURITIES TO BE REDEEMED	11
3.3. NOTICE OF REDEMPTION	11
3.4. EFFECT OF NOTICE OF REDEMPTION	12
3.5. DEPOSIT OF REDEMPTION PRICE	12
3.6. SECURITIES REDEEMED IN PART	12
ARTICLE 4 – COVENANTS	12
4.1. PAYMENT OF SECURITIES	12
4.2. SEC REPORTS	12
4.3. WAIVER OF STAY, EXTENSION OR USURY LAWS	13
4.4. COMPLIANCE CERTIFICATE	13
4.5. CORPORATE EXISTENCE	13
ARTICLE 5 – SUCCESSOR CORPORATION	13
5.1. LIMITATION ON CONSOLIDATION, MERGER AND SALE OF ASSETS	13
5.2. SUCCESSOR PERSON SUBSTITUTED	14
ARTICLE 6 – DEFAULTS AND REMEDIES	14
6.1. EVENTS OF DEFAULT	14
6.2. ACCELERATION	15
6.3. REMEDIES	15
6.4. WAIVER OF PAST DEFAULTS AND EVENTS OF DEFAULT	15
6.5. CONTROL BY MAJORITY	15
6.6. LIMITATION ON SUITS	15
6.7. RIGHTS OF HOLDERS TO RECEIVE PAYMENT	16
6.8. COLLECTION SUIT BY TRUSTEE	16
6.9. TRUSTEE MAY FILE PROOFS OF CLAIM	16
6.10. PRIORITIES	16
6.11. UNDERTAKING FOR COSTS	17
ARTICLE 7 – TRUSTEE	17
7.1. DUTIES OF TRUSTEE	17
7.2. RIGHTS OF TRUSTEE	18
7.3. INDIVIDUAL RIGHTS OF TRUSTEE	18
7.4. TRUSTEE’S DISCLAIMER	18
7.5. NOTICE OF DEFAULT	18
7.6. REPORTS BY TRUSTEE TO HOLDERS	19
7.7. COMPENSATION AND INDEMNITY	19

7.8. REPLACEMENT OF TRUSTEE	19
7.9. SUCCESSOR TRUSTEE BY CONSOLIDATION, MERGER OR CONVERSION	20
7.10. ELIGIBILITY; DISQUALIFICATION	20
7.11. PREFERENTIAL COLLECTION OF CLAIMS AGAINST COMPANY	20
7.12. PAYING AGENTS	20
ARTICLE 8 – AMENDMENTS, SUPPLEMENTS AND WAIVERS	20
8.1. WITHOUT CONSENT OF HOLDERS	20
8.2. WITH CONSENT OF HOLDERS	21
8.3. COMPLIANCE WITH TRUST INDENTURE ACT	21
8.4. REVOCATION AND EFFECT OF CONSENTS	22
8.5. NOTATION ON OR EXCHANGE OF SECURITIES	22
8.6. TRUSTEE TO SIGN AMENDMENTS, ETC.	22
ARTICLE 9 – DISCHARGE OF INDENTURE; DEFEASANCE	22
9.1. DISCHARGE OF INDENTURE	22
9.2. LEGAL DEFEASANCE	23
9.3. COVENANT DEFEASANCE	23
9.4. CONDITIONS TO LEGAL DEFEASANCE OR COVENANT DEFEASANCE	23
9.5. DEPOSITED MONEY AND U.S. AND FOREIGN GOVERNMENT OBLIGATIONS TO BE HELD IN TRUST; OTHER MISCELLANEOUS PROVISIONS	24
9.6. REINSTATEMENT	24
9.7. MONEYS HELD BY PAYING AGENT	24
9.8. MONEYS HELD BY TRUSTEE	24
ARTICLE 10 – MISCELLANEOUS	25
10.1. TRUST INDENTURE ACT CONTROLS	25
10.2. NOTICES	25
10.3. COMMUNICATIONS BY HOLDERS WITH OTHER HOLDERS	26
10.4. CERTIFICATE AND OPINION AS TO CONDITIONS PRECEDENT	26
10.5. STATEMENT REQUIRED IN CERTIFICATE AND OPINION	26
10.6. RULES BY TRUSTEE AND AGENTS	26
10.7. BUSINESS DAYS; LEGAL HOLIDAYS; PLACE OF PAYMENT	26
10.8. GOVERNING LAW	26
10.9. NO ADVERSE INTERPRETATION OF OTHER AGREEMENTS	26
10.10. NO RECOURSE AGAINST OTHERS	27
10.11. SUCCESSORS	27
10.12. MULTIPLE COUNTERPARTS	27
10.13. TABLE OF CONTENTS, HEADINGS, ETC.	27
10.14. SEVERABILITY	27
10.15. SECURITIES IN A FOREIGN CURRENCY OR IN EUROS	27
10.16. JUDGMENT CURRENCY	28

TIA SECTION		INDENTURE SECTION
310(a)(1)(2)(5)		7.10
310(a)(3)(4)		Inapplicable
310(b)		7.8; 7.10
310(c)		Inapplicable
311(a)(b)		7.11
311(c)		Inapplicable
312(a)		2.6
312(b)(c)		10.3
313(a)(b)		7.6
313(c)		7.6; 10.2
313(d)		7.6
314(a)		4.2; 4.4; 10.2
314(b)		N/A
314(c)(1)(2)		10.4;10.5
314(c)(3)		Inapplicable
314(d)		Inapplicable
314(e)		10.5
314(f)		Inapplicable
315(a)		7.1, 7.2
315(b)		7.5; 10.2
315(c)		7.1
315(d)		7.1; 7.2
315(e)		6.11
316(a)(last sentence)		2.10
316(a)(1)(A)		6.5
316(a)(1)(B)		6.4
316(a)(2)		8.2
316(b)		6.7
316(c)		8.4
317(a)(1)		6.8
317(a)(2)		6.9
317(b)		2.5; 7.12
318(a)		10.1


TERM		DEFINED IN SECTION
“Bankruptcy Law”		6.1
“Business Day”		10.7
“Covenant Defeasance”		9.3
“Custodian”		6.1
“Event of Default”		6.1
“Journal”		10.15
“Judgment Currency”		10.16
“Legal Defeasance”		9.2
“Legal Holiday”		10.7
“Market Exchange Rate”		10.15
“Paying Agent”		2.4
“Place of Payment”		10.7
“Registrar”		2.4
“Required Currency”		10.16
“Service Agent”		2.4

, as [Authenticating Agent for] the Trustee

By
	Authorized Officer

	CAREDX, INC.

	By:
		Name:
		Title:

	[Name of Trustee]

	By:
		Name:
		Title:

	By:
		Name:
		Title:

No.		$
		CUSIP No.