As filed with the Securities and Exchange Commission on December 14, 2020
Registration No. 333-
Castle Biosciences Inc (CSTL)
Delaware | | | 77-0701774 |
(State or other jurisdiction of incorporation or organization) | | | (I.R.S. Employer Identification Number) |
Large accelerated filer | | | ☐ | | | Accelerated filer | | | ☐ |
Non-accelerated filer | | | ☒ | | | Smaller reporting company | | | ☒ |
| | | | | Emerging growth company | | | ☒ |
Title of Each Class of Securities to be Registered | | | Proposed Maximum Aggregate Offering Price | | | Amount of Registration Fee |
Common Stock, par value $0.001 per share | | | (1) | | | (2) |
Preferred Stock, par value $0.001 per share | | | (1) | | | (2) |
Debt Securities | | | (1) | | | (2) |
Warrants | | | (1) | | | (2) |
(1) | Omitted pursuant to General Instruction II.E of Form S-3. An indeterminate number or amount, as the case may be, of common stock, preferred stock, debt securities and warrants are being registered hereunder as may from time to time be issued at indeterminate prices. The securities being registered hereunder may be convertible into or exchangeable or exercisable for other securities of any identified class, and may be sold separately or in combination with the other securities registered hereunder. In addition to the securities that may be issued directly under this registration statement, there is being registered hereunder such indeterminate aggregate number or amount, as the case may be, of the securities of each identified class as may from time to time be issued upon the conversion, exchange, settlement or exercise of other securities offered hereby. Separate consideration may or may not be received for securities that are issuable upon the conversion or exercise of, or in exchange for, other securities offered hereby. |
(2) | Pursuant to Rules 456(b) and 457(r), the Registrant is deferring payment of all applicable registration fees. |

• | designation or classification; |
• | aggregate principal amount or aggregate offering price; |
• | maturity, if applicable; |
• | original issue discount, if any; |
• | rates and times of payment of interest or dividends, if any; |
• | redemption, conversion, exchange or sinking fund terms, if any; |
• | conversion or exchange prices or rates, if any, and, if applicable, any provisions for changes to or adjustments in the conversion or exchange prices or rates and in the securities or other property receivable upon conversion or exchange; |
• | ranking, if applicable; |
• | restrictive covenants, if any; |
• | voting or other rights, if any; and |
• | important U.S. federal income tax considerations. |
• | the names of those underwriters or agents; |
• | applicable fees, discounts and commissions to be paid to them; |
• | details regarding options to purchase additional securities, if any; and |
• | the estimated net proceeds to us. |
• | We rely upon a small number of third-party payors for a significant portion of our revenue. |
• | Our method of recognizing revenue may not reflect our underlying business. |
• | We have incurred significant losses since inception, and we may never achieve sustained profitability. |
• | We are an early, commercial-stage company and have a limited operating history, which may make it difficult to evaluate our current business and predict our future performance. |
• | Our financial results could fluctuate in the future, causing the market price of our stock to decline substantially. |
• | If our internal control over financial reporting is ineffective, we may not be able to accurately report our financial results or file our periodic reports in a timely manner. |
• | The terms of our credit facility place restrictions on our operating and financial flexibility. |
• | We may need to raise additional capital to commercialize new products, to expand operations or to fund existing operations. |
• | We have been, and may continue to be, adversely impacted by the COVID-19 pandemic, which has caused decreased test report volume. |
• | Our revenue heavily relies upon the sale of a single product and our current or future products may not achieve or maintain significant commercial market acceptance. |
• | Billing for our products is complex and we require substantial time and resources to collect payment. |
• | We rely on third parties for tumor sample collection, preparation and delivery. |
• | A depletion or loss of our tumor sample database could significantly harm our business. |
• | If our primary clinical laboratory facility becomes damaged or inoperable or we are required to vacate our existing facility, our ability to conduct our laboratory analysis and pursue our research and development efforts may be jeopardized. |
• | Our current or future products may not achieve or maintain significant commercial market acceptance. |
• | New product development is lengthy and complex and our revenues could be limited if we are unable to increase and support adoption of our products by healthcare providers. |
• | We may experience limits on our revenue if we are unable to increase and support adoption of our products by both physicians and other healthcare providers. |
• | We rely on limited or sole suppliers for some of the reagents, equipment, chips and other materials used by our products, and we may not be able to find replacements or transition to alternative suppliers. |
• | The sizes of the markets for our current and future products have not been established with precision and may be smaller than we estimate. |
• | The diagnostic testing industry is subject to rapid change, which could make our current or future products obsolete. |
• | We currently have limited reimbursement coverage for our lead product, DecisionDx-Melanoma, and if third-party payors, including government and commercial payors, do not provide sufficient coverage of, or adequate reimbursement for, our products, our commercial success will be negatively affected. |
• | We conduct business in a heavily regulated industry and failure to comply with regulatory requirements, including those established by the U.S. Food and Drug Administration, or changes in enforcement discretion for laboratory developed tests could harm our business. |
• | Data from our clinical studies may change materially, which could harm our business. |
• | Changes in health care policy or healthcare statutes and regulations or our ability to comply with applicable requirements could cause a material adverse effect to our business and operations. |
• | If we are unable to obtain and maintain sufficient intellectual property protection for our technology, our ability to successfully commercialize our products may be impaired. |
• | Our commercial success depends significantly on our ability to operate without infringing upon the intellectual property rights of third parties. |
• | We rely on information technology systems that we license from third parties and other royalty-bearing license agreements. |
• | We are highly dependent on the services of our key personnel, including our President and Chief Executive Officer. |
• | Our employees and any current or potential commercial partners may engage in misconduct or other improper activities, including non-compliance with regulatory standards and requirements and insider trading. |
• | Our business may be negatively impacted by cyber security threats, natural disasters and public health crises. |
• | Product or professional liability lawsuits against us could cause us to incur substantial liabilities and could limit our commercialization of our products. |
• | The stock price of our common stock may be volatile or may decline regardless of our operating performance, and you may lose all or part of your investment. |
• | We have broad direction in the use of working capital and may not use it effectively or in ways that increase our share price. |
• | The concentration of our stock ownership will likely limit your ability to influence corporate matters, including the ability to influence the outcome of director elections and other matters requiring stockholder approval. |
• | Delaware law and provisions in our amended and restated certificate of incorporation and amended and restated bylaws could make a merger, tender offer or proxy contest difficult, thereby depressing the trading price of our common stock. |
• | Our amended and restated certificate of incorporation provides that the Court of Chancery of the State of Delaware is the exclusive forum for certain disputes between us and our stockholders, which could limit our stockholders’ ability to obtain a favorable judicial forum for disputes with us or our directors, officers or employees. |
• | estimates of our addressable market, future revenue, expenses, capital requirements and our needs for additional financing; |
• | expectations with respect to reimbursement for our products, including third-party payor reimbursement and coverage decisions; |
• | anticipated cost, timing and success of our products in development, and our plans to research, develop and commercialize new tests; |
• | the impact of the COVID-19 pandemic on our business; |
• | our ability to obtain funding for our operations, including funding necessary to complete the expansion of our operations and development of our product candidates; |
• | the implementation of our business model and strategic plans for our products, technologies and businesses; |
• | our ability to manage and grow our business by expanding our sales to existing customers or introducing our products to new customers; |
• | our ability to develop and maintain sales and marketing capabilities; |
• | regulatory developments in the United States and foreign countries; |
• | the performance of our third-party suppliers; |
• | the success of competing diagnostic products that are or become available; |
• | our ability to attract and retain key personnel; |
• | our expectations regarding the period during which we qualify as an emerging growth company under the JOBS Act; and |
• | our expectations regarding our ability to obtain and maintain intellectual property protection for our products and our ability to operate our business without infringing on the intellectual property rights of others. |
• | the title and stated value; |
• | the number of shares we are offering; |
• | the liquidation preference per share; |
• | the purchase price per share; |
• | the dividend rate per share, dividend period, payment date or dates and method of calculation for dividends; |
• | whether dividends will be cumulative or non-cumulative and, if cumulative, the date from which dividends will accumulate; |
• | our right, if any, to defer payment of dividends and the maximum length of any such deferral period; |
• | the procedures for any auction and remarketing, if any; |
• | the provisions for a sinking fund, if any; |
• | the provisions for redemption or repurchase, if applicable, and any restrictions on our ability to exercise those redemption and repurchase rights; |
• | any listing of the preferred stock on any securities exchange or market; |
• | whether the preferred stock will be convertible into our common stock or other securities of ours, including warrants, and, if applicable, the conversion price, or how it will be calculated, and under what circumstances and the mechanism by which it may be adjusted, and the conversion period; |
• | whether the preferred stock will be exchangeable into debt securities or other securities of ours, and, if applicable, the exchange price, or how it will be calculated, and under what circumstances it may be adjusted, and the exchange period; |
• | voting rights, if any; |
• | preemptive rights, if any; |
• | restrictions on transfer, sale or other assignment, if any; |
• | whether interests in the preferred stock will be represented by depositary shares; |
• | a discussion of any material or special U.S. federal income tax considerations applicable to the preferred stock; |
• | the relative ranking and preferences of the preferred stock as to dividend rights and rights if we liquidate, dissolve or wind up our affairs; |
• | any limitations on issuances of any class or series of preferred stock ranking senior to or on parity with the series of preferred stock being issued as to dividend rights and rights if we liquidate, dissolve or wind up our affairs; and |
• | any other specific terms, rights, preferences, privileges, qualifications or limitations of, or restrictions on the preferred stock. |
• | prior to such time the board of directors of the corporation approved either the business combination or the transaction which resulted in the stockholder becoming an interested stockholder; |
• | upon consummation of the transaction which resulted in the stockholder becoming an interested stockholder, the interested stockholder owned at least 85% of the voting stock of the corporation outstanding at the time the transaction commenced, excluding for purposes of determining the voting stock outstanding (but not the outstanding voting stock owned by the interested stockholder) those shares owned (1) by persons who are directors and also officers and (2) employee stock plans in which employee participants do not have the right to determine confidentially whether shares held subject to the plan will be tendered in a tender or exchange offer; or |
• | at or subsequent to such time, the business combination is approved by the board of directors and authorized at an annual or special meeting of stockholders, and not by written consent, by the affirmative vote of at least 66-2/3% of the outstanding voting stock which is not owned by the interested stockholder. |
• | any merger or consolidation involving the corporation and the interested stockholder; |
• | any sale, transfer, pledge or other disposition involving the interested stockholder of 10% or more of the assets of the corporation; |
• | subject to exceptions, any transaction that results in the issuance or transfer by the corporation of any stock of the corporation to the interested stockholder; |
• | subject to exceptions, any transaction involving the corporation that has the effect of increasing the proportionate share of the stock of any class or series of the corporation beneficially owned by the interested stockholder; and |
• | the receipt by the interested stockholder of the benefit of any loans, advances, guarantees, pledges or other financial benefits provided by or through the corporation. |
• | permit our board of directors to issue up to 10,000,000 shares of preferred stock, with any rights, preferences and privileges as they may designate (including the right to approve an acquisition or other change in our control); |
• | provide that the authorized number of directors may be changed only by resolution of the board of directors; |
• | provide that the board of directors or any individual director may only be removed with cause and the affirmative vote of the holders of at least 66-2/3% of the voting power of all of our then-outstanding common stock; |
• | provide that all vacancies, including newly created directorships, may, except as otherwise required by law, be filled by the affirmative vote of a majority of directors then in office, even if less than a quorum; |
• | divide our board of directors into three classes; |
• | require that any action to be taken by our stockholders must be effected at a duly called annual or special meeting of stockholders and not be taken by written consent; |
• | provide that stockholders seeking to present proposals before a meeting of stockholders or to nominate candidates for election as directors at a meeting of stockholders must provide notice in writing in a timely manner and also specify requirements as to the form and content of a stockholder’s notice; |
• | do not provide for cumulative voting rights (therefore allowing the holders of a majority of the shares of common stock entitled to vote in any election of directors to elect all of the directors standing for election, if they should so choose); |
• | provide that special meetings of our stockholders may be called only by the chairman of the board, our Chief Executive Officer or by the board of directors pursuant to a resolution adopted by a majority of the total number of authorized directors; |
• | provide that, unless we consent in writing to the selection of an alternative forum, the Court of Chancery of the State of Delaware (or, if and only if the Court of Chancery of the State of Delaware lacks subject matter jurisdiction, any state court located within the State of Delaware or, if and only if all such state courts lack subject matter jurisdiction, the federal district court for the District of Delaware) will be the sole and exclusive forum for the following types of actions or proceedings under Delaware statutory or common law: (i) any derivative action or proceeding brought on our behalf, (ii) any action or proceeding asserting a claim of breach of a fiduciary duty owed by any of our current or former directors, officers or other employees to us or our stockholders; (iii) any action or proceeding asserting a claim against us or any of our current or former directors, officers or other employees, arising out of or pursuant to any provision of the DGCL, our certificate of incorporation or our bylaws; (iv) any action or proceeding to interpret, apply, enforce or determine the validity of our certificate of incorporation or our bylaws; (v) any action or proceeding as to which the DGCL confers jurisdiction to the Court of Chancery of the State of Delaware; and (vi) any action asserting a claim against us or any of our directors, officers or other employees governed by the internal affairs doctrine, in all cases to the fullest extent permitted by law and subject to the court’s having personal jurisdiction over the indispensable parties named as defendants; provided these provisions of our amended and restated certificate of incorporation and amended and restated bylaws will not apply to suits brought to enforce a duty or liability created by the Exchange Act, or any other claim for which the federal courts have exclusive jurisdiction; and |
• | provide that unless we consent in writing to the selection of an alternative forum, the federal district courts of the United States of America shall be the exclusive forum for the resolution of any complaint asserting a cause of action arising under the Securities Act, subject to and contingent upon a final adjudication in the State of Delaware of the enforceability of such exclusive forum provision. |
• | We will describe in the applicable prospectus supplement the terms of the series of debt securities being offered, including: |
• | the title of the series of debt securities; |
• | any limit upon the aggregate principal amount that may be issued; |
• | the maturity date or dates; |
• | the form of the debt securities of the series; |
• | the applicability of any guarantees; |
• | whether or not the debt securities will be secured or unsecured, and the terms of any secured debt; |
• | whether the debt securities rank as senior debt, senior subordinated debt, subordinated debt or any combination thereof, and the terms of any subordination; |
• | if the price (expressed as a percentage of the aggregate principal amount thereof) at which such debt securities will be issued is a price other than the principal amount thereof, the portion of the principal amount thereof payable upon declaration of acceleration of the maturity thereof, or if applicable, the portion of the principal amount of such debt securities that is convertible into another security or the method by which any such portion shall be determined; |
• | the interest rate or rates, which may be fixed or variable, or the method for determining the rate and the date interest will begin to accrue, the dates interest will be payable and the regular record dates for interest payment dates or the method for determining such dates; |
• | our right, if any, to defer payment of interest and the maximum length of any such deferral period; |
• | if applicable, the date or dates after which, or the period or periods during which, and the price or prices at which, we may, at our option, redeem the series of debt securities pursuant to any optional or provisional redemption provisions and the terms of those redemption provisions; |
• | the date or dates, if any, on which, and the price or prices at which we are obligated, pursuant to any mandatory sinking fund or analogous fund provisions or otherwise, to redeem, or at the holder’s option to purchase, the series of debt securities and the currency or currency unit in which the debt securities are payable; |
• | the denominations in which we will issue the series of debt securities, if other than denominations of $1,000 and any integral multiple thereof; |
• | any and all terms, if applicable, relating to any auction or remarketing of the debt securities of that series and any security for our obligations with respect to such debt securities and any other terms which may be advisable in connection with the marketing of debt securities of that series; |
• | whether the debt securities of the series shall be issued in whole or in part in the form of a global security or securities; the terms and conditions, if any, upon which such global security or securities may be exchanged in whole or in part for other individual securities; and the depositary for such global security or securities; |
• | if applicable, the provisions relating to conversion or exchange of any debt securities of the series and the terms and conditions upon which such debt securities will be so convertible or exchangeable, including the conversion or exchange price, as applicable, or how it will be calculated and may be adjusted, any mandatory or optional (at our option or the holders’ option) conversion or exchange features, the applicable conversion or exchange period and the manner of settlement for any conversion or exchange; |
• | if other than the full principal amount thereof, the portion of the principal amount of debt securities of the series which shall be payable upon declaration of acceleration of the maturity thereof; |
• | additions to or changes in the covenants applicable to the particular debt securities being issued, including, among others, the consolidation, merger or sale covenant; |
• | additions to or changes in the events of default with respect to the securities and any change in the right of the trustee or the holders to declare the principal, premium, if any, and interest, if any, with respect to such securities to be due and payable; |
• | additions to or changes in or deletions of the provisions relating to covenant defeasance and legal defeasance; |
• | additions to or changes in the provisions relating to satisfaction and discharge of the indenture; |
• | additions to or changes in the provisions relating to the modification of the indenture both with and without the consent of holders of debt securities issued under the indenture; |
• | the currency of payment of debt securities if other than U.S. dollars and the manner of determining the equivalent amount in U.S. dollars; |
• | whether interest will be payable in cash or additional debt securities at our or the holders’ option and the terms and conditions upon which the election may be made; |
• | the terms and conditions, if any, upon which we will pay amounts in addition to the stated interest, premium, if any and principal amounts of the debt securities of the series to any holder that is not a “United States person” for federal tax purposes; |
• | any restrictions on transfer, sale or assignment of the debt securities of the series; and |
• | any other specific terms, preferences, rights or limitations of, or restrictions on, the debt securities, any other additions or changes in the provisions of the indenture, and any terms that may be required by us or advisable under applicable laws or regulations. |
• | if we fail to pay any installment of interest on any series of debt securities, as and when the same shall become due and payable, and such default continues for a period of 90 days; provided, however, that a valid extension of an interest payment period by us in accordance with the terms of any indenture supplemental thereto shall not constitute a default in the payment of interest for this purpose; |
• | if we fail to pay the principal of, or premium, if any, on any series of debt securities as and when the same shall become due and payable whether at maturity, upon redemption, by declaration or otherwise, or in any payment required by any sinking or analogous fund established with respect to such series; provided, however, that a valid extension of the maturity of such debt securities in accordance with the terms of any indenture supplemental thereto shall not constitute a default in the payment of principal or premium, if any; |
• | if we fail to observe or perform any other covenant or agreement contained in the debt securities or the indenture, other than a covenant specifically relating to another series of debt securities, and our failure continues for 90 days after we receive written notice of such failure, requiring the same to be remedied and stating that such is a notice of default thereunder, from the trustee or holders of at least 25% in aggregate principal amount of the outstanding debt securities of the applicable series; and |
• | if specified events of bankruptcy, insolvency or reorganization occur. |
• | the direction so given by the holder is not in conflict with any law or the applicable indenture; and |
• | subject to its duties under the Trust Indenture Act, the trustee need not take any action that might involve it in personal liability or might be unduly prejudicial to the holders not involved in the proceeding. |
• | the holder has given written notice to the trustee of a continuing event of default with respect to that series; |
• | the holders of at least 25% in aggregate principal amount of the outstanding debt securities of that series have made written request, |
• | such holders have offered to the trustee indemnity satisfactory to it against the costs, expenses and liabilities to be incurred by the trustee in compliance with the request; and |
• | the trustee does not institute the proceeding, and does not receive from the holders of a majority in aggregate principal amount of the outstanding debt securities of that series other conflicting directions within 90 days after the notice, request and offer. |
• | to cure any ambiguity, defect or inconsistency in the indenture or in the debt securities of any series; |
• | to comply with the provisions described above under “Description of Debt Securities—Consolidation, Merger or Sale;” |
• | to provide for uncertificated debt securities in addition to or in place of certificated debt securities; |
• | to add to our covenants, restrictions, conditions or provisions such new covenants, restrictions, conditions or provisions for the benefit of the holders of all or any series of debt securities, to make the occurrence, or the occurrence and the continuance, of a default in any such additional covenants, restrictions, conditions or provisions an event of default or to surrender any right or power conferred upon us in the indenture; |
• | to add to, delete from or revise the conditions, limitations, and restrictions on the authorized amount, terms, or purposes of issue, authentication and delivery of debt securities, as set forth in the indenture; |
• | to make any change that does not adversely affect the interests of any holder of debt securities of any series in any material respect; |
• | to provide for the issuance of and establish the form and terms and conditions of the debt securities of any series as provided above under “Description of Debt Securities—General” to establish the form of any certifications required to be furnished pursuant to the terms of the indenture or any series of debt securities, or to add to the rights of the holders of any series of debt securities; |
• | to evidence and provide for the acceptance of appointment under any indenture by a successor trustee; or |
• | to comply with any requirements of the SEC in connection with the qualification of any indenture under the Trust Indenture Act. |
• | extending the fixed maturity of any debt securities of any series; |
• | reducing the principal amount, reducing the rate of or extending the time of payment of interest, or reducing any premium payable upon the redemption of any series of any debt securities; or |
• | reducing the percentage of debt securities, the holders of which are required to consent to any amendment, supplement, modification or waiver. |
• | provide for payment; |
• | register the transfer or exchange of debt securities of the series; |
• | replace stolen, lost or mutilated debt securities of the series; |
• | pay principal of and premium and interest on any debt securities of the series; |
• | maintain paying agencies; |
• | hold monies for payment in trust; |
• | recover excess money held by the trustee; |
• | compensate and indemnify the trustee; and |
• | appoint any successor trustee. |
• | issue, register the transfer of, or exchange any debt securities of that series during a period beginning at the opening of business 15 days before the day of mailing of a notice of redemption of any debt securities that may be selected for redemption and ending at the close of business on the day of the mailing; or |
• | register the transfer of or exchange any debt securities so selected for redemption, in whole or in part, except the unredeemed portion of any debt securities we are redeeming in part. |
• | the title of such securities; |
• | the offering price or prices and aggregate number of warrants offered; |
• | the currency or currencies for which the warrants may be purchased; |
• | if applicable, the designation and terms of the securities with which the warrants are issued and the number of warrants issued with each such security or each principal amount of such security; |
• | if applicable, the date on and after which the warrants and the related securities will be separately transferable; |
• | if applicable, the minimum or maximum amount of such warrants which may be exercised at any one time; |
• | in the case of warrants to purchase debt securities, the principal amount of debt securities purchasable upon exercise of one warrant and the price at which, and currency in which, this principal amount of debt securities may be purchased upon such exercise; |
• | in the case of warrants to purchase common stock or preferred stock, the number of shares of common stock or preferred stock, as the case may be, purchasable upon the exercise of one warrant and the price at which, and the currency in which, these shares may be purchased upon such exercise; |
• | the effect of any merger, consolidation, sale or other disposition of our business on the warrant agreements and the warrants; |
• | the terms of any rights to redeem or call the warrants; |
• | the terms of any rights to force the exercise of the warrants; |
• | any provisions for changes to or adjustments in the exercise price or number of securities issuable upon exercise of the warrants; |
• | the dates on which the right to exercise the warrants will commence and expire; |
• | the manner in which the warrant agreements and warrants may be modified; |
• | a discussion of any material or special U.S. federal income tax consequences of holding or exercising the warrants; |
• | the terms of the securities issuable upon exercise of the warrants; and |
• | any other specific terms, preferences, rights or limitations of or restrictions on the warrants. |
• | in the case of warrants to purchase debt securities, the right to receive payments of principal of, or premium, if any, or interest on, the debt securities purchasable upon exercise or to enforce covenants in the applicable indenture; or |
• | in the case of warrants to purchase common stock or preferred stock, the right to receive dividends, if any, or, payments upon our liquidation, dissolution or winding up or to exercise voting rights, if any. |
• | how it handles securities payments and notices; |
• | whether it imposes fees or charges; |
• | how it would handle a request for the holders’ consent, if ever required; |
• | whether and how you can instruct it to send you securities registered in your own name so you can be a holder, if that is permitted in the future; |
• | how it would exercise rights under the securities if there were a default or other event triggering the need for holders to act to protect their interests; and |
• | if the securities are in book-entry form, how the depositary’s rules and procedures will affect these matters. |
• | an investor cannot cause the securities to be registered in his or her name, and cannot obtain non-global certificates for his or her interest in the securities, except in the special situations we describe below; |
• | an investor will be an indirect holder and must look to his or her own bank or broker for payments on the securities and protection of his or her legal rights relating to the securities, as we describe above; |
• | an investor may not be able to sell interests in the securities to some insurance companies and to other institutions that are required by law to own their securities in non-book-entry form; |
• | an investor may not be able to pledge his or her interest in the global security in circumstances where certificates representing the securities must be delivered to the lender or other beneficiary of the pledge in order for the pledge to be effective; |
• | the depositary’s policies, which may change from time to time, will govern payments, transfers, exchanges and other matters relating to an investor’s interest in the global security; |
• | we and any applicable trustee have no responsibility for any aspect of the depositary’s actions or for its records of ownership interests in the global security, nor will we or any applicable trustee supervise the depositary in any way; |
• | the depositary may, and we understand that DTC will, require that those who purchase and sell interests in the global security within its book-entry system use immediately available funds, and your broker or bank may require you to do so as well; and |
• | financial institutions that participate in the depositary’s book-entry system, and through which an investor holds its interest in the global security, may also have their own policies affecting payments, notices and other matters relating to the securities. |
• | if the depositary notifies us that it is unwilling, unable or no longer qualified to continue as depositary for that global security and we do not appoint another institution to act as depositary within 90 days; |
• | if we notify any applicable trustee that we wish to terminate that global security; or |
• | if an event of default has occurred with regard to securities represented by that global security and has not been cured or waived. |
• | at a fixed price or prices, which may be changed; |
• | at market prices prevailing at the time of sale; |
• | at prices related to such prevailing market prices; or |
• | at negotiated prices. |
• | on or through the facilities of the Nasdaq Global Market or any other securities exchange or quotation or trading service on which such securities may be listed, quoted or traded at the time of sale; and/or |
• | to or through a market maker other than on the Nasdaq Global Market or such other securities exchanges or quotation or trading services. |
• | the name or names of any underwriters, dealers or agents, if any; |
• | the purchase price of the securities and the proceeds we will receive from the sale; |
• | any options pursuant to which underwriters may purchase additional securities from us; |
• | any agency fees or underwriting discounts and other items constituting agents’ or underwriters’ compensation; |
• | any public offering price; |
• | any discounts or concessions allowed or reallowed or paid to dealers; and |
• | any securities exchange or market on which the securities may be listed. |
• | our Annual Report on Form 10-K for the year ended December 31, 2019 filed with the SEC on March 10, 2020; |
• | the information specifically incorporated by reference into our Annual Report on Form 10-K for the year ended December 31, 2019 from our Definitive Proxy Statement on Schedule 14A, filed with the SEC on April 23, 2020; |
• | our Quarterly Reports on Form 10-Q for the quarters ended March 31, 2020, June 30, 2020 and September 30, 2020, filed with the SEC on May 11, 2020, August 10, 2020 and November 9, 2020, respectively; |
• | our Current Reports on Form 8-K (other than information furnished rather than filed) filed with the SEC on March 5, 2020, April 1, 2020, April 15, 2020, May 28, 2020, June 2, 2020, June 9, 2020, June 30, 2020, August 20, 2020 and December 14, 2020; and |
• | the description of our common stock, which is registered under Section 12 of the Exchange Act, in our registration statement on Form 8-A, filed with the SEC on July 15, 2019, including any amendments or reports filed for the purpose of updating such description, including any amendment or report filed for the purpose of updating such description, including any amendment or report filed for the purposes of updating such description, including Exhibit 4.1 to our Annual Report on Form 10-K for the year ended December 31, 2019, filed with the SEC on March 10, 2020. |
Item 14. | Other Expenses of Issuance and Distribution. |
SEC registration fee | | | $* |
FINRA filing fee | | | 225,500 |
Accounting fees and expenses | | | ** |
Legal fees and expenses | | | ** |
Transfer agent and registrar fees and expenses | | | ** |
Trustee fees and expenses | | | ** |
Blue sky fees and expenses | | | |
Printing and miscellaneous expenses | | | ** |
Total | | | $** |
* | Pursuant to Rules 456(b) and 457(r), we are deferring payment of all applicable registration fees. |
** | The amount of securities and number of offerings are indeterminable and the expenses cannot be estimated at this time. An estimate of the aggregate expenses in connection with the sale and distribution of securities being offered will be included in the applicable prospectus supplement. |
Item 15. | Indemnification of Directors and Officers. |
• | transaction from which the director derives an improper personal benefit; |
• | act or omission not in good faith or that involves intentional misconduct or a knowing violation of law; |
• | unlawful payment of dividends or redemption of shares; or |
• | breach of a director’s duty of loyalty to the corporation or its stockholders. |
• | indemnification beyond that permitted by the Delaware General Corporation Law; |
• | indemnification for any proceeding with respect to the unlawful payment of remuneration to the director or officer; |
• | indemnification for certain proceedings involving a final judgment that the director or officer is required to disgorge profits from the purchase or sale of our stock; |
• | indemnification for proceedings involving a final judgment that the director’s or officer’s conduct was in bad faith, knowingly fraudulent or deliberately dishonest or constituted willful misconduct or a breach of his or her duty of loyalty, but only to the extent of such specific determination; |
• | indemnification for proceedings or claims brought by an officer or director against us or any of our directors, officers, employees or agents, except for claims to establish a right of indemnification or proceedings or claims approved by our board of directors or required by law; |
• | indemnification for settlements the director or officer enters into without our consent; or |
• | indemnification in violation of any undertaking required by the Securities Act of 1933, as amended, or the Securities Act, or in any registration statement filed by us. |
Item 16. | Exhibits. |
Exhibit Number | | | Description of Document |
1.1* | | | Form of Underwriting Agreement. |
| | | Amended and Restated Certificate of Incorporation of the Registrant, incorporated by reference to Exhibit 3.1 of the Registrant’s Current Report on Form 8-K filed with the SEC on July 29, 2019. | |
| | | Amended and Restated Bylaws of the Registrant, incorporated by reference to Exhibit 3.2 of the Registrant’s Current Report on Form 8-K filed with the SEC on July 29, 2019. | |
| | | Form of Common Stock Certificate of the Registrant, incorporated by reference to Exhibit 4.1 of the Registrant’s Registration Statement on Form S-1 (File No. 333-232369), as amended, originally filed with the SEC on June 26, 2019. | |
| | | Sixth Amended and Restated Investors’ Rights Agreement, dated July 12, 2019, by and among the Registrant and certain of its stockholders, incorporated by reference to Exhibit 4.2 of the Registrant’s Registration Statement on Form S-1 (File No. 333-232369), as amended, originally filed with the SEC on June 26, 2019. | |
| | | Form of warrant to purchase Series F redeemable convertible preferred stock issued to Oxford Finance LLC and Silicon Valley Bank on March 31, 2017, incorporated by reference to Exhibit 4.6 of the Registrant’s Registration Statement on Form S-1 (File No. 333-232369), as amended, originally filed with the SEC on June 26, 2019. | |
| | | Form of warrant to purchase Series F redeemable convertible preferred stock issued to Oxford Finance LLC and Silicon Valley Bank on November 30, 2018, incorporated by reference to Exhibit 4.7 of the Registrant’s Registration Statement on Form S-1 (File No. 333-232369), as amended, originally filed with the SEC on June 26, 2019. | |
| | | Form of Indenture. | |
4.6* | | | Form of Debt Securities. |
4.7* | | | Form of Specimen Preferred Stock Certificate and Certificate of Designations of Preferred Stock. |
| | | Form of Common Stock Warrant Agreement and Warrant Certificate. | |
| | | Form of Preferred Stock Warrant Agreement and Warrant Certificate. | |
| | | Form of Debt Securities Warrant Agreement and Warrant Certificate. | |
| | | Opinion of Cooley LLP. | |
| | | Consent of Independent Registered Public Accounting Firm. | |
| | | Consent of Cooley LLP (included in Exhibit 5.1). | |
| | | Power of Attorney (included on signature page). | |
25.1** | | | Statement of Eligibility of Trustee under the Indenture. |
* | To be filed by amendment or by a report filed under the Exchange Act and incorporated herein by reference, if applicable. |
** | To be filed in accordance with the requirements of Section 305(b)(2) of the Trust Indenture Act of 1939, as amended, and the applicable rules thereunder. |
Item 17. | Undertakings. |
(1) | To file, during any period in which offers or sales are being made, a post-effective amendment to this registration statement: |
(i) | To include any prospectus required by Section 10(a)(3) of the Securities Act; |
(ii) | To reflect in the prospectus any facts or events arising after the effective date of the registration statement (or the most recent post-effective amendment thereof) which, individually or in the aggregate, represent a fundamental change in the information set forth in the registration statement. Notwithstanding the foregoing, any increase or decrease in volume of securities offered (if the total dollar value of securities offered would not exceed that which was registered) and any deviation from the low or high end of the estimated maximum offering range may be reflected in |
(iii) | To include any material information with respect to the plan of distribution not previously disclosed in the registration statement or any material change to such information in the registration statement; |
(2) | That, for the purpose of determining any liability under the Securities Act, each such post-effective amendment shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof. |
(3) | To remove from registration by means of a post-effective amendment any of the securities being registered which remain unsold at the termination of the offering. |
(4) | That, for the purpose of determining liability under the Securities Act to any purchaser: |
(i) | Each prospectus filed by the registrant pursuant to Rule 424(b)(3) shall be deemed to be part of the registration statement as of the date the filed prospectus was deemed part of and included in the registration statement; and |
(ii) | Each prospectus required to be filed pursuant to Rule 424(b)(2), (b)(5), or (b)(7) as part of a registration statement in reliance on Rule 430B relating to an offering made pursuant to Rule 415(a)(1)(i), (vii), or (x) for the purpose of providing the information required by Section 10(a) of the Securities Act shall be deemed to be part of and included in the registration statement as of the earlier of the date such form of prospectus is first used after effectiveness or the date of the first contract of sale of securities in the offering described in the prospectus. As provided in Rule 430B, for liability purposes of the issuer and any person that is at that date an underwriter, such date shall be deemed to be a new effective date of the registration statement relating to the securities in the registration statement to which that prospectus relates, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof. Provided, however, that no statement made in a registration statement or prospectus that is part of the registration statement or made in a document incorporated or deemed incorporated by reference into the registration statement or prospectus that is part of the registration statement will, as to a purchaser with a time of contract of sale prior to such effective date, supersede or modify any statement that was made in the registration statement or prospectus that was part of the registration statement or made in any such document immediately prior to such effective date. |
(5) | That, for the purpose of determining liability of the registrant under the Securities Act to any purchaser in the initial distribution of the securities, the undersigned registrant undertakes that in a primary offering of securities of the undersigned registrant pursuant to this registration statement, regardless of the underwriting method used to sell the securities to the purchaser, if the securities are offered or sold to such purchaser by means of any of the following communications, the undersigned registrant will be a seller to the purchaser and will be considered to offer or sell such securities to such purchaser: (i) any preliminary prospectus or prospectus of the undersigned registrant relating to the offering required to be filed pursuant to Rule 424; (ii) any free writing prospectus relating to the offering prepared by or on behalf of the undersigned registrant or used or referred to by the undersigned registrant; (iii) the portion |
(6) | That, for purposes of determining any liability under the Securities Act, each filing of the registrant’s annual report pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan’s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the registration statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof. |
(7) | To file an application for the purpose of determining the eligibility of the trustee to act under subsection (a) of Section 310 of the Trust Indenture Act in accordance with the rules and regulations prescribed by the SEC under Section 305(b)(2) of the Trust Indenture Act. |
| | | CASTLE BIOSCIENCES, INC. | ||||
| | | | | |||
| | | By: | | | /s/ Derek J. Maetzold | |
| | | | | Derek J. Maetzold | ||
| | | | | President and Chief Executive Officer | ||
Signature | | | Title | | | Date |
/s/ Derek J. Maetzold | | | President, Chief Executive Officer and Director (Principal Executive Officer) | | | December 14, 2020 |
Derek J. Maetzold | | |||||
| | | | | |||
/s/ Frank Stokes | | | Chief Financial Officer (Principal Financial Officer and Principal Accounting Officer) | | | December 14, 2020 |
Frank Stokes | | |||||
| | | | | |||
/s/ Daniel M. Bradbury | | | Director | | | December 14, 2020 |
Daniel M. Bradbury | | |||||
| | | | | |||
/s/ Mara G. Aspinall | | | Director | | | December 14, 2020 |
Mara G. Aspinall | | |||||
| | | | | |||
/s/ G. Bradley Cole | | | Director | | | December 14, 2020 |
G. Bradley Cole | | |||||
| | | | | |||
/s/ Joseph C. Cook III | | | Director | | | December 14, 2020 |
Joseph C. Cook III | | |||||
| | | | | |||
/s/ Miles D. Harrison | | | Director | | | December 14, 2020 |
Miles D. Harrison | | |||||
| | | | | |||
/s/ David Kabakoff, Ph.D. | | | Director | | | December 14, 2020 |
David Kabakoff, Ph.D. | |
|
Page
|
||
|
ARTICLE 1 DEFINITIONS
|
1
|
|
|
Section 1.01
|
Definitions of Terms
|
1
|
|
ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES
|
5
|
|
|
Section 2.01
|
Designation and Terms of Securities
|
5
|
|
Section 2.02
|
Form of Securities and Trustee’s Certificate
|
8
|
|
Section 2.03
|
Denominations: Provisions for Payment
|
8
|
|
Section 2.04
|
Execution and Authentications
|
10
|
|
Section 2.05
|
Registration of Transfer and Exchange
|
11
|
|
Section 2.06
|
Temporary Securities
|
12
|
|
Section 2.07
|
Mutilated, Destroyed, Lost or Stolen Securities
|
12
|
|
Section 2.08
|
Cancellation
|
13
|
|
Section 2.09
|
Benefits of Indenture
|
13
|
|
Section 2.10
|
Authenticating Agent
|
14
|
|
Section 2.11
|
Global Securities
|
14
|
|
Section 2.12
|
CUSIP Numbers
|
15
|
|
ARTICLE 3 REDEMPTION OF SECURITIES AND SINKING FUND PROVISIONS
|
16
|
|
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Section 3.01
|
Redemption
|
16
|
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Section 3.02
|
Notice of Redemption
|
16
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Section 3.03
|
Payment Upon Redemption
|
17
|
|
Section 3.04
|
Sinking Fund
|
17
|
|
Section 3.05
|
Satisfaction of Sinking Fund Payments with Securities
|
18
|
|
Section 3.06
|
Redemption of Securities for Sinking Fund
|
18
|
|
ARTICLE 4 COVENANTS
|
18
|
|
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Section 4.01
|
Payment of Principal, Premium and Interest
|
18
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|
Section 4.02
|
Maintenance of Office or Agency
|
19
|
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Section 4.03
|
Paying Agents
|
19
|
|
Section 4.04
|
Appointment to Fill Vacancy in Office of Trustee
|
20
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| Page | ||
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ARTICLE 5 SECURITYHOLDERS’ LISTS AND REPORTS BY THE COMPANY AND THE TRUSTEE
|
20
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|
|
Section 5.01
|
Company to Furnish Trustee Names and Addresses of Securityholders
|
20
|
|
Section 5.02
|
Preservation Of Information; Communications With Securityholders
|
21
|
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Section 5.03
|
Reports by the Company
|
21
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Section 5.04
|
Reports by the Trustee
|
22
|
|
ARTICLE 6 REMEDIES OF THE TRUSTEE AND SECURITYHOLDERS ON EVENT OF DEFAULT
|
22
|
|
|
Section 6.01
|
Events of Default
|
22
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|
Section 6.02
|
Collection of Indebtedness and Suits for Enforcement by Trustee
|
24
|
|
Section 6.03
|
Application of Moneys Collected
|
24
|
|
Section 6.04
|
Limitation on Suits
|
26
|
|
Section 6.05
|
Rights and Remedies Cumulative; Delay or Omission Not Waiver
|
26
|
|
Section 6.06
|
Control by Securityholders
|
27
|
|
Section 6.07
|
Undertaking to Pay Costs
|
27
|
|
ARTICLE 7 CONCERNING THE TRUSTEE
|
28
|
|
|
Section 7.01
|
Certain Duties and Responsibilities of Trustee
|
28
|
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Section 7.02
|
Certain Rights of Trustee
|
29
|
|
Section 7.03
|
Trustee Not Responsible for Recitals or Issuance or Securities
|
31
|
|
Section 7.04
|
May Hold Securities
|
32
|
|
Section 7.05
|
Moneys Held in Trust
|
32
|
|
Section 7.06
|
Compensation and Reimbursement
|
32
|
|
Section 7.07
|
Reliance on Officer’s Certificate
|
33
|
|
Section 7.08
|
Disqualification; Conflicting Interests
|
33
|
|
Section 7.09
|
Corporate Trustee Required; Eligibility
|
33
|
|
Section 7.10
|
Resignation and Removal; Appointment of Successor
|
33
|
|
Section 7.11
|
Acceptance of Appointment By Successor
|
35
|
|
Section 7.12
|
Merger, Conversion, Consolidation or Succession to Business
|
36
|
| Page | ||
|
Section 7.13
|
Preferential Collection of Claims Against the Company
|
36
|
|
Section 7.14
|
Notice of Default.
|
36
|
|
ARTICLE 8 CONCERNING THE SECURITYHOLDERS
|
37
|
|
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Section 8.01
|
Evidence of Action by Securityholders
|
37
|
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Section 8.02
|
Proof of Execution by Securityholders
|
37
|
|
Section 8.03
|
Who May be Deemed Owners
|
38
|
|
Section 8.04
|
Certain Securities Owned by Company Disregarded
|
38
|
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Section 8.05
|
Actions Binding on Future Securityholders
|
38
|
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ARTICLE 9 SUPPLEMENTAL INDENTURES
|
39
|
|
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Section 9.01
|
Supplemental Indentures Without the Consent of Securityholders
|
39
|
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Section 9.02
|
Supplemental Indentures With Consent of Securityholders
|
40
|
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Section 9.03
|
Effect of Supplemental Indentures
|
40
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Section 9.04
|
Securities Affected by Supplemental Indentures
|
40
|
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Section 9.05
|
Execution of Supplemental Indentures
|
41
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ARTICLE 10 SUCCESSOR ENTITY
|
41
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Section 10.01
|
Company May Consolidate, Etc.
|
41
|
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Section 10.02
|
Successor Entity Substituted
|
42
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ARTICLE 11 SATISFACTION AND DISCHARGE
|
42
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Section 11.01
|
Satisfaction and Discharge of Indenture
|
42
|
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Section 11.02
|
Discharge of Obligations
|
43
|
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Section 11.03
|
Deposited Moneys to be Held in Trust
|
43
|
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Section 11.04
|
Payment of Moneys Held by Paying Agents
|
43
|
|
Section 11.05
|
Repayment to Company
|
44
|
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ARTICLE 12 IMMUNITY OF INCORPORATORS, STOCKHOLDERS, OFFICERS AND DIRECTORS
|
44
|
|
|
Section 12.01
|
No Recourse
|
44
|
|
ARTICLE 13 MISCELLANEOUS PROVISIONS
|
45
|
|
|
Section 13.01
|
Effect on Successors and Assigns
|
45
|
|
Section 13.02
|
Actions by Successor
|
45
|
|
Section 13.03
|
Surrender of Company Powers
|
45
|
| Page | ||
|
Section 13.04
|
Notices
|
45
|
|
Section 13.05
|
Governing Law; Jury Trial Waiver
|
45
|
|
Section 13.06
|
Treatment of Securities as Debt
|
46
|
|
Section 13.07
|
Certificates and Opinions as to Conditions Precedent
|
46
|
|
Section 13.08
|
Payments on Business Days
|
46
|
|
Section 13.09
|
Conflict with Trust Indenture Act
|
46
|
|
Section 13.10
|
Counterparts
|
47
|
|
Section 13.11
|
Separability
|
47
|
|
Section 13.12
|
Compliance Certificates
|
47
|
|
Section 13.13
|
Patriot Act
|
47
|
|
Section 13.14
|
Force Majeure
|
47
|
|
Section 13.12
|
Table of Contents; Headings
|
47
|
|
Castle Biosciences, Inc.
|
||
|
By:
|
||
|
Name:
|
||
|
Title:
|
||
|
[Trustee],
as Trustee
|
||
|
By:
|
||
|
Name:
|
||
|
Title:
|
||
|
Section of Trust Indenture Act of 1939, as Amended
|
Section of Indenture
|
|
|
310(a)
|
7.09
|
|
|
310(b)
|
7.08
|
|
|
7.10
|
||
|
310(c)
|
Inapplicable
|
|
|
311(a)
|
7.13
|
|
|
311(b)
|
7.13
|
|
|
311(c)
|
Inapplicable
|
|
|
312(a)
|
5.01
|
|
|
5.02(a)
|
||
|
312(b)
|
5.02(c)
|
|
|
312(c)
|
5.02(c)
|
|
|
313(a)
|
5.04(a)
|
|
|
313(b)
|
5.04(b)
|
|
|
313(c)
|
5.04(a)
|
|
|
5.04(b)
|
||
|
313(d)
|
5.04(c)
|
|
|
314(a)
|
5.03
|
|
|
13.12
|
||
|
314(b)
|
Inapplicable
|
|
|
314(c)
|
13.07(a)
|
|
|
314(d)
|
Inapplicable
|
|
|
314(e)
|
13.07(b)
|
|
|
314(f)
|
Inapplicable
|
|
|
315(a)
|
7.01(a)
|
|
|
7.01(b)
|
||
|
315(b)
|
7.14
|
|
|
315(c)
|
7.01
|
|
|
315(d)
|
7.01(b)
|
|
|
315(e)
|
6.07
|
|
|
316(a)
|
6.06
|
|
|
8.04
|
||
|
316(b)
|
6.04
|
|
|
316(c)
|
8.01
|
|
|
317(a)
|
6.02
|
|
|
317(b)
|
4.03
|
|
|
318(a)
|
13.09
|
| (1) |
This Cross-Reference Table does not constitute part of the Indenture and shall not have any bearing on the interpretation of any of its terms or provisions.
|
|
CASTLE BIOSCIENCES, INC.
|
||
|
By:
|
||
|
Name:
|
||
|
Title:
|
||
|
[WARRANT AGENT], as Warrant Agent
|
||
|
By:
|
||
|
Name:
|
||
|
Title:
|
||
|
[Form if Warrants are attached to Other Securities and are not immediately detachable.]
|
[Prior to , this Warrant Certificate cannot be transferred or exchanged unless attached to a [Title of Other Securities].]
|
|
|
[Form of Legend if Warrants are not immediately exercisable.]
|
[Prior to , Warrants evidenced by this Warrant Certificate cannot be exercised.]
|
|
No.
|
Warrants
|
|
Dated:
|
||||
|
CASTLE BIOSCIENCES, INC.
|
||||
|
By:
|
||||
|
Name:
|
||||
|
Title:
|
||||
|
Countersigned:
|
||||
|
[WARRANT AGENT], as Warrant Agent
|
||||
|
By:
|
||||
|
Name:
|
||||
|
Title:
|
||||
|
Dated
|
Name
|
||||
|
Please Print
|
|||||
|
Address:
|
|||||
|
(Insert Social Security or Other Identifying Number of Holder)
|
|||||
|
Signature Guaranteed
|
|||||
|
Signature
|
|||||
|
(Please print name and address including zip code)
|
Please print Social Security or other identifying number
|
|
Dated
|
|||
|
Signature
|
|||
|
Signature Guaranteed
|
||
|
CASTLE BIOSCIENCES, INC.
|
||
|
By:
|
||
|
Name:
|
||
|
Title:
|
||
|
[WARRANT AGENT], as Warrant Agent
|
||
|
By:
|
||
|
Name:
|
||
|
Title:
|
||
|
[Form if Warrants are attached to Other Securities and are not immediately detachable.]
|
[Prior to , this Warrant Certificate cannot be transferred or exchanged unless attached to a [Title of Other Securities].]
|
|
|
[Form of Legend if Warrants are not immediately exercisable.]
|
[Prior to , Warrants evidenced by this Warrant Certificate cannot be exercised.]
|
|
No.
|
Warrants
|
|
Dated:
|
||||
|
CASTLE BIOSCIENCES, INC.
|
||||
|
By:
|
||||
|
Name:
|
||||
|
Title:
|
||||
|
Countersigned:
|
||||
|
[WARRANT AGENT], as Warrant Agent
|
||||
|
By:
|
||||
|
Name:
|
||||
|
Title:
|
||||
|
Dated
|
Name
|
||||
|
Please Print
|
|||||
|
Address:
|
|||||
|
(Insert Social Security or Other Identifying Number of Holder)
|
|||||
|
Signature Guaranteed
|
|||||
|
Signature
|
|||||
|
(Please print name and address including zip code)
|
Please print Social Security or other identifying number
|
|
Dated
|
|||
|
Signature
|
|||
|
Signature Guaranteed
|
||
|
CASTLE BIOSCIENCES, INC.
|
||
|
By:
|
||
|
Name:
|
||
|
Title:
|
||
|
[WARRANT AGENT], as Warrant Agent
|
||
|
By:
|
||
|
Name:
|
||
|
Title:
|
||
|
[Form if Warrants are attached to Other Securities and are not immediately detachable.]
|
[Prior to , this Warrant Certificate cannot be transferred or exchanged unless attached to a [Title of Other Securities].]
|
|
|
[Form of Legend if Warrants are not immediately exercisable.]
|
[Prior to , Warrants evidenced by this Warrant Certificate cannot be exercised.]
|
|
No.
|
Warrants
|
|
Dated:
|
||||
|
CASTLE BIOSCIENCES, INC.
|
||||
|
By:
|
||||
|
Name:
|
||||
|
Title:
|
||||
|
Countersigned:
|
||||
|
[WARRANT AGENT], as Warrant Agent
|
||||
|
By:
|
||||
|
Name:
|
||||
|
Title:
|
||||
|
Dated
|
Name
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Address:
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(Insert Social Security or Other Identifying Number of Holder)
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Signature Guaranteed
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Signature
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(Please print name and address including zip code)
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Please print Social Security or other identifying number
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Dated
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Signature
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Signature Guaranteed
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shares of common stock, $0.001 par value per share, of the Company (the “Common Stock”);
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shares of preferred stock, $0.001 par value per share, of the Company (the “Preferred Stock”);
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debt securities, in one or more series (the “Debt Securities”), which may be issued pursuant to an indenture to be dated on or about the date of the first issuance of Debt
Securities thereunder, by and between a trustee to be selected by the Company (the “Trustee”) and the Company, in the form filed as Exhibit 4.5 to the Registration Statement and one
or more indentures supplemental thereto with respect to any particular series of Debt Securities (the “Indenture”); and
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warrants to purchase Common Stock, Preferred Stock or Debt Securities (the “Warrants”), which may be issued under one or more warrant agreements, to be dated on or about the date of the first
issuance of the Warrants thereunder, by and between a warrant agent to be selected by the Company (the “Warrant Agent”) and the Company, in the forms filed as Exhibits 4.8, 4.9 and 4.10 to the
Registration Statement, respectively (each, a “Warrant Agreement”).
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| 1. |
With respect to the Common Stock offered under the Registration Statement, provided that: (i) the Registration Statement and any required post-effective amendment thereto have become effective under the Securities Act, and the Base
Prospectus and any and all Prospectus Supplement(s) required by applicable laws have been delivered and filed as required by such laws; (ii) the issuance of the Common Stock has been duly authorized by all necessary corporate action on the
part of the Company; (iii) the issuance and sale of the Common Stock do not violate any applicable law, are in conformity with the Company’s then operative certificate of incorporation (the “Certificate of
Incorporation”) and bylaws (the “Bylaws”), do not result in a default under or breach of any agreement or instrument binding upon the Company and comply with any applicable requirement or
restriction imposed by any court or governmental body having jurisdiction over the Company; and (iv) the certificates, if any, for the Common Stock have been duly executed by the Company, countersigned by the transfer agent therefor and duly
delivered to the purchasers thereof against payment therefor, then the Common Stock, when issued and sold as contemplated in the Registration Statement, the Base Prospectus and the related Prospectus Supplement(s), and in accordance with a
duly authorized, executed and delivered purchase, underwriting or similar agreement, or upon conversion of any convertible Preferred Stock, or convertible Debt Securities in accordance with their terms, or upon exercise of any Warrants in
accordance with their terms, will be validly issued, fully paid and nonassessable.
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| 2. |
With respect to the Preferred Stock offered under the Registration Statement, provided that: (i) the Registration Statement and any required post-effective amendment thereto have become effective under the Securities Act and the Base
Prospectus and any and all Prospectus Supplement(s) required by applicable laws have been delivered and filed as required by such laws; (ii) the terms and issuance of the Preferred Stock have been duly authorized by all necessary corporate
action on the part of the Company; (iii) the terms of the shares of Preferred Stock and their issuance and sale do not violate any applicable law, are in conformity with the Certificate of Incorporation and Bylaws, do not result in a default
under or breach of any agreement or instrument binding upon the Company and comply with any applicable requirement or restriction imposed by any court or governmental body having jurisdiction over the Company; and (iv) the certificates, if
any, for the Preferred Stock have been duly executed by the Company, countersigned by the transfer agent therefor and duly delivered to the purchasers thereof against payment therefor, then the Preferred Stock, when issued and sold as
contemplated in the Registration Statement, the Base Prospectus and the related Prospectus Supplement(s) and in accordance with a duly authorized, executed and delivered purchase, underwriting or similar agreement, or upon conversion of any
convertible Debt Securities in accordance with their terms, or upon exercise of any Warrants in accordance with their terms, will be validly issued, fully paid and nonassessable.
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| 3. |
With respect to any series of the Debt Securities issued under the Indenture, and offered under the Registration Statement, provided that (i) the Registration Statement and any required post-effective amendment thereto have become
effective under the Securities Act and the Base Prospectus and any and all Prospectus Supplement(s) required by applicable laws have been delivered and filed as required by such laws; (ii) the Indenture has been duly authorized by the Company
and the Trustee by all necessary corporate action; (iii) the Indenture in substantially the form filed as an exhibit to the Registration Statement, has been duly executed and delivered by the Company and the Trustee and has been qualified
under the Trust Indenture Act of 1939, as amended; (iv) the issuance and terms of the Debt Securities have been duly authorized by the Company by all necessary corporate action; (v) the terms of the Debt Securities and of their issuance and
sale have been duly established in conformity with the Indenture so as not to violate any applicable law or result in a default under or breach of any agreement or instrument binding upon the Company, so as to be in conformity with the
Certificate of Incorporation and Bylaws, and so as to comply with any requirement or restriction imposed by any court or governmental body having jurisdiction over the Company; and (vi) the notes representing the Debt Securities have been
duly executed and delivered by the Company and authenticated by the Trustee pursuant to the Indenture and delivered against payment therefor, then the Debt Securities, when issued and sold in accordance with the Indenture and a duly
authorized, executed and delivered purchase, underwriting or similar agreement, or upon exercise of any Warrants in accordance with their terms, will be valid and legally binding obligations of the Company, except as may be limited by
bankruptcy, insolvency, reorganization, moratorium or other similar laws relating to or affecting creditors’ rights generally, and by general equitable principles (regardless of whether considered in a proceeding at law or in equity).
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| 4. |
With respect to the Warrants issued under the Warrant Agreements and offered under the Registration Statement, provided that (i) the Registration Statement and any required post-effective amendment thereto have become effective under the
Securities Act and the Base Prospectus and any and all Prospectus Supplement(s) required by applicable laws have been delivered and filed as required by such laws; (ii) the applicable Warrant Agreement has been duly authorized by the Company
and the Warrant Agent by all necessary corporate action; (iii) the applicable Warrant Agreement has been duly executed and delivered by the Company and the Warrant Agent; (iv) the issuance and terms of the Warrants have been duly authorized
by the Company by all necessary corporate action; (v) the terms of the Warrants and of their issuance and sale have been duly established in conformity with the applicable Warrant Agreement and as described in the Registration Statement, the
Base Prospectus and the related Prospectus Supplement(s), so as not to violate any applicable law or result in a default under or breach of any agreement or instrument binding upon the Company, so as to be in conformity with the Certificate
of Incorporation and Bylaws, and so as to comply with any requirement or restriction imposed by any court or governmental body having jurisdiction over the Company; and (vi) the Warrants have been duly executed and delivered by the Company
and authenticated by the Warrant Agent pursuant to the applicable Warrant Agreement and delivered against payment therefor, then the Warrants, when issued and sold as contemplated in the Registration Statement, the Base Prospectus and the
Prospectus Supplement(s) and in accordance with the applicable Warrant Agreement and a duly authorized, executed and delivered purchase, underwriting or similar agreement, will be valid and legally binding obligations of the Company, except
as may be limited by bankruptcy, insolvency, reorganization, moratorium or other similar laws relating to or affecting creditors’ rights generally, and by general equitable principles (regardless of whether considered in a proceeding at law
or in equity).
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By:
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/s/ Karen E. Deschaine | |
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Karen E. Deschaine
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