PERCEPTIVE ADVISORS LLC

CIK

1224962

City

NEW YORK

State / Country

Stock

FOLD — AMICUS THERAPEUTICS, INC.

Top Portfolio Positions

90 positions · $5,091,752,531 total · as of Mar 31, 2026

Ticker	Company	Shares	Value (USD)	% of Portfolio
PRAX	Praxis Precision Medicines, Inc. Healthcare	2,035,986	$655,974,329	12.88%
CELC	Celcuity Inc. Healthcare	3,127,200	$356,938,608	7.01%
ASND	Ascendis Pharma A/S Healthcare	1,531,421	$350,281,925	6.88%
ROIV	Roivant Sciences Ltd. Healthcare	8,285,461	$229,507,269	4.51%
CNTA	Centessa Pharmaceuticals plc Healthcare	5,258,903	$208,883,627	4.10%
RYTM	Rhythm Pharmaceuticals, Inc. Healthcare	2,373,795	$206,448,951	4.05%
SYRE	Spyre Therapeutics, Inc. Healthcare	3,783,225	$190,825,869	3.75%
NUVL	Nuvalent, Inc. Healthcare	1,580,505	$161,922,737	3.18%
EWTX	Edgewise Therapeutics, Inc. Healthcare	4,423,974	$139,355,181	2.74%
PTGX	Protagonist Therapeutics, Inc Healthcare	1,230,879	$129,734,646	2.55%

26 quarters · across all stocks

23 quarters on record

Report Date	Value (USD)	Shares	Change	Type	Discretion	Filed
2025-12-31	$90,720,918	6,370,851	0.0%	Shares	Sole	2026-02-17
2025-09-30	$50,202,305	6,370,851	-14.1%	Shares	Sole	2025-11-14
2025-06-30	$42,475,515	7,412,830	-65.5%	Shares	Sole	2025-08-14
2025-03-31	$175,150,540	21,464,527	-23.5%	Shares	Sole	2025-08-06
2024-09-30	$299,653,630	28,057,456	0.0%	Shares	Sole	2024-11-14
2024-06-30	$278,329,963	28,057,456	0.0%	Shares	Sole	2024-08-16
2024-03-31	$330,516,831	28,057,456	0.0%	Shares	Sole	2024-08-06
2023-12-31	$398,135,300	28,057,456	+1.3%	Shares	Sole	2024-02-26
2023-09-30	$336,745,870	27,692,917	+0.1%	Shares	Sole	2023-11-14
2023-06-30	$347,446,237	27,662,917	0.0%	Shares	Sole	2023-08-24
2023-03-31	$306,781,749	27,662,917	+0.1%	Shares	Sole	2023-05-16
2022-12-31	$337,520,016	27,642,917	+1.0%	Shares	Sole	2023-02-14
2022-09-30	$285,773,253	27,372,917	+1.8%	Shares	Sole	2022-11-14
2022-06-30	$288,858,013	26,895,532	-2.4%	Shares	Sole	2022-08-15
2022-03-31	$260,953,852	27,555,845	+3.8%	Shares	Sole	2022-05-16
2021-12-31	$306,761,566	26,559,443	0.0%	Shares	Sole	2022-04-13
2021-09-30	$253,642,680	26,559,443	+14.9%	Shares	Sole	2021-11-15
2021-06-30	$222,889,611	23,121,329	+1.1%	Shares	Sole	2021-08-17
2021-03-31	$225,869,930	22,861,329	-9.0%	Shares	Sole	2021-08-13
2020-12-31	$579,837,188	25,112,048	-0.0%	Shares	Sole	2021-02-16
2020-09-30	$354,723,317	25,122,048	-0.2%	Shares	Sole	2020-11-16
2020-06-30	$379,750,049	25,182,364	0.0%	Shares	Sole	2020-08-17
2020-03-31	$232,685,043	25,182,364	—	Shares	Sole	2020-05-18
No 13F history on record for this holder in this stock.