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Equibles

CNTA

Centessa Pharmaceuticals plc

Company with tickers: CNTA

CIK
1847903
CUSIP
152309100
Shares Outstanding
154,731,309
Investor Relations
https://centessa.com/investors/
13F Activity (30d)
7 filings 6 filers

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 161
Total Value: $6,404,649,895
Total Shares: 161,244,964
Showing 1–100 of 175 holdings by value · page 1 of 2

Institutional Ownership Trend

22 quarters

Holder Concentration

Across 161 13F filers · Δ vs Dec 31, 2025
Top Holder
13.3%
Dec 2023 → Mar 2026 · range 13.3% – 28.0%
−0.5 pts
Top 5
39.0%
Dec 2023 → Mar 2026 · range 39.0% – 67.3%
−5.8 pts
Top 10
57.8%
Dec 2023 → Mar 2026 · range 57.8% – 84.6%
−3.5 pts
HHI
471
Dec 2023 → Mar 2026 · range 471 – 1,293
Broadly held−68

Quarterly Activity

vs Dec 31, 2025
New
48
Increased
52
Decreased
44
Sold Out
34
Unchanged
17
Holder count: +14
Institutional value: +77.2%
Shares held: +11.6%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Large Avoro Capital Advisors LLC +8,305,355 22,860,910
Mega Capital World Investors +3,673,849 4,832,548
Mid EcoR1 Capital, LLC +3,295,800 6,410,800
Mega MORGAN STANLEY +3,159,255 4,268,353
Mid PERCEPTIVE ADVISORS LLC +2,341,269 5,258,903

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mid GENERAL ATLANTIC, L.P. −4,762,885 1,354,830
Mid Siren, L.L.C. −2,974,053 1,053,464
Large ADAGE CAPITAL PARTNERS GP, L.L.C. −2,356,731 8,925,010
Mega FMR LLC −2,109,892 6,852,047
Mega FRANKLIN RESOURCES INC −1,683,899 684,482

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Large Pentwater Capital Management LP 8,170,000 $324,512,400
Mid Paradigm Biocapital Advisors LP 3,574,048 $141,961,186
Mid ALPINE ASSOCIATES MANAGEMENT INC. 865,500 $34,377,660
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. 702,254 $27,893,527
Mid EVENTIDE ASSET MANAGEMENT, LLC 668,142 $26,538,600

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega PRICE T ROWE ASSOCIATES INC /MD/ 3,927,343 $98,222,848
Small STEMPOINT CAPITAL LP 1,229,114 $30,740,141
Mid Sofinnova Investments, Inc. 1,104,274 $27,617,892
Mid Commodore Capital LP 1,000,000 $25,010,000
Mid ARMISTICE CAPITAL, LLC 500,000 $12,505,000
Filter: New 48 Increased 52 Reduced 44 Sold out 34 Unchanged 17
Showing 100 of 175
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Small Medicxi Ventures Management (Jersey) Ltd $792,936,596 12.38% 19,963,157
Large Avoro Capital Advisors LLC $454,017,672 7.09% 11,430,455
Large Avoro Capital Advisors LLC $454,017,672 7.09% 11,430,455
Small Index Venture Life Associates VI Ltd $395,682,259 6.18% 9,961,789
Large ADAGE CAPITAL PARTNERS GP, L.L.C. $354,501,397 5.54% 8,925,010
Large Pentwater Capital Management LP $324,512,400 5.07% 8,170,000
Mega FMR LLC $272,163,305 4.25% 6,852,047
Mid EcoR1 Capital, LLC $238,320,000 3.72% 6,000,000
Mid PERCEPTIVE ADVISORS LLC $208,883,627 3.26% 5,258,903
Mega Capital World Investors $191,948,806 3.00% 4,832,548
Large FARALLON CAPITAL MANAGEMENT LLC $191,013,480 2.98% 4,809,000
Mid TCG Crossover Management, LLC $170,258,985 2.66% 4,286,480
Mega MORGAN STANLEY $169,538,978 2.65% 4,268,353
Mid Paradigm Biocapital Advisors LP $141,961,186 2.22% 3,574,048
Mega JANUS HENDERSON GROUP PLC $138,741,045 2.17% 3,492,977
Mid Deep Track Capital, LP $125,437,388 1.96% 3,158,041
Mid Logos Global Management LP $84,405,000 1.32% 2,125,000
Large RTW INVESTMENTS, LP $81,591,831 1.27% 2,054,175
Large FEDERATED HERMES, INC. $81,403,717 1.27% 2,049,439
Mid BRAIDWELL LP $78,914,424 1.23% 1,986,768
Mega BANK OF AMERICA CORP /DE/ Bank $76,755,165 1.20% 1,932,406
Mid MAVERICK CAPITAL LTD $73,660,263 1.15% 1,854,488
Mid First Light Asset Management, LLC $62,002,562 0.97% 1,560,991
Mid Affinity Asset Advisors, LLC $55,608,000 0.87% 1,400,000
Small Foresite Capital Management VI LLC $54,178,834 0.85% 1,364,019
Mid GENERAL ATLANTIC, L.P. $53,813,847 0.84% 1,354,830
Mega GOLDMAN SACHS GROUP INC $45,461,922 0.71% 1,144,560
Mid Siren, L.L.C. $41,843,590 0.65% 1,053,464
Mid Cormorant Asset Management, LP $41,706,000 0.65% 1,050,000
Mid ALPINE ASSOCIATES MANAGEMENT INC. $34,377,660 0.54% 865,500
Large Woodline Partners LP $34,123,650 0.53% 859,105
Large Balyasny Asset Management L.P. $33,874,328 0.53% 852,828
Small Octagon Capital Advisors LP $29,790,000 0.47% 750,000
Mega MILLENNIUM MANAGEMENT LLC $28,682,646 0.45% 722,121
Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. $27,893,527 0.44% 702,254
Mega AMERICAN CENTURY COMPANIES INC $27,304,600 0.43% 687,427
Mega FRANKLIN RESOURCES INC $27,187,624 0.42% 684,482
Large BAKER BROS. ADVISORS LP $26,642,229 0.42% 670,751
Mid EVENTIDE ASSET MANAGEMENT, LLC $26,538,600 0.41% 668,142
Large TORONTO DOMINION BANK Bank $26,010,642 0.41% 654,850
Mid TIG Advisors, LLC $25,751,508 0.40% 648,326
Mega D. E. Shaw & Co., Inc. $25,572,053 0.40% 643,808
Mid Bain Capital Life Sciences Investors, LLC $25,222,200 0.39% 635,000
Large Qube Research & Technologies Ltd $24,946,106 0.39% 628,049
Mega BlackRock, Inc. $24,841,681 0.39% 625,420
Mega CITADEL ADVISORS LLC $23,760,383 0.37% 598,197
Small 5AM Venture Management, LLC $23,075,135 0.36% 580,945
Small PFM Health Sciences, LP $20,981,057 0.33% 528,224
Mid Weiss Asset Management LP $20,273,366 0.32% 510,407
Small Spruce Street Capital LP $19,456,802 0.30% 489,849
Mega JPMORGAN CHASE & CO $18,970,152 0.30% 477,597
Small SILVERARC CAPITAL MANAGEMENT, LLC $18,523,223 0.29% 466,345
Mid EcoR1 Capital, LLC $16,316,976 0.25% 410,800
Large Trexquant Investment LP $15,528,573 0.24% 390,951
Mega UBS Group AG $14,296,775 0.22% 359,939
Mid Rock Springs Capital Management LP $13,974,608 0.22% 351,828
Mid GLAZER CAPITAL, LLC $12,909,039 0.20% 325,001
Large Alyeska Investment Group, L.P. $12,727,479 0.20% 320,430
Large Point72 Asset Management, L.P. $12,208,140 0.19% 307,355
Mid ROYCE & ASSOCIATES LP $11,044,702 0.17% 278,064
Large Caption Management, LLC $10,887,887 0.17% 274,116
Mid Nantahala Capital Management, LLC $10,120,775 0.16% 254,803
Mega TD Asset Management Inc $9,613,987 0.15% 242,044
Micro HighMark Wealth Management LLC $9,405,100 0.15% 236,785
Small Eagle Health Investments LP $8,511,638 0.13% 214,291
Mid SummitTX Capital, L.P. $8,215,962 0.13% 206,847
Mega DEUTSCHE BANK AG\ Bank $7,545,250 0.12% 189,961
Large RENAISSANCE TECHNOLOGIES LLC $7,348,200 0.11% 185,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $6,887,448 0.11% 173,400
Large Schonfeld Strategic Advisors LLC $6,829,178 0.11% 171,933
Mega T. Rowe Price Investment Management, Inc. $6,753,035 0.11% 170,016
Large MARSHALL WACE, LLP $6,679,989 0.10% 168,177
Large FRED ALGER MANAGEMENT, LLC $6,679,712 0.10% 168,170
Large Holocene Advisors, LP $6,392,616 0.10% 160,942
Mid Atom Investors LP $6,295,977 0.10% 158,509
Mid Burkehill Global Management, LP $5,958,000 0.09% 150,000
Small PLATINUM INVESTMENT MANAGEMENT LTD $5,471,072 0.09% 137,741
Large LMR Partners LLP $4,965,000 0.08% 125,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $4,718,736 0.07% 118,800
Large HRT FINANCIAL LP $4,646,922 0.07% 116,992
Mega JANE STREET GROUP, LLC $4,532,052 0.07% 114,100
Large VOLORIDGE INVESTMENT MANAGEMENT, LLC $4,446,892 0.07% 111,956
Mega Legal & General Group Plc $4,377,422 0.07% 110,207
Large Freestone Grove Partners LP $4,342,468 0.07% 109,327
Mega GEODE CAPITAL MANAGEMENT, LLC $4,280,942 0.07% 107,778
Mid AQR Arbitrage LLC $3,893,672 0.06% 98,028
Large Pictet Asset Management Holding SA $3,849,265 0.06% 96,910
Mid Y-Intercept (Hong Kong) Ltd $3,827,697 0.06% 96,367
Small Caitong International Asset Management Co., Ltd $3,721,168 0.06% 93,685
Mega CITADEL ADVISORS LLC $3,320,592 0.05% 83,600
Small HARVEST MANAGEMENT LLC $3,177,600 0.05% 80,000
Mega CITIGROUP INC $2,950,242 0.05% 74,276
Large Jain Global LLC $2,840,496 0.04% 71,513
Mega MILLENNIUM MANAGEMENT LLC $2,740,680 0.04% 69,000
Mid Virtu Financial LLC $2,692,023 0.04% 67,775
Mega TWO SIGMA INVESTMENTS, LP $2,377,003 0.04% 59,844
Small CSS LLC/IL $2,065,440 0.03% 52,000
Large Squarepoint Ops LLC $2,010,070 0.03% 50,606
Mega CITADEL ADVISORS LLC $1,914,504 0.03% 48,200
Small WATER ISLAND CAPITAL LLC $1,628,520 0.03% 41,000

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