SAN 6-K

FORM 6-K

SECURITIES ANDEXCHANGE COMMISSION

Washington, D.C.20549

Report of ForeignIssuer

Pursuant to Rule13a-16 or 15d-16 of

the SecuritiesExchange Act of 1934

For the month of September, 2024

Commission File Number: 001-12518

Banco Santander,S.A.

(Exact name ofregistrant as specified in its charter)

Ciudad GrupoSantander

28660 Boadilladel Monte (Madrid) Spain

(Address of principalexecutive office)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:

Banco Santander,S.A.

TABLE OF CONTENTS

Item1

Banco Santander, S.A. (the “Bank” or “Banco Santander”), in compliance with the Securities Market legislation, hereby communicates the following:

OTHER RELEVANT INFORMATION

Reference is made to our notice of inside information of 27 August 2024 (official registry number 2371) (the “Buy-back Commencement Communication”), relating to the buyback programme of own shares (the “Buy-back Programme”) approved by the Board of Directors of Banco Santander.

Pursuant to article 5 of Regulation (EU) no. 596/2014 on Market Abuse of 16 April 2014, and articles 2.2 and 2.3 of Commission Delegated Regulation (EU) 2016/1052, of 8 March 2016, the Bank informs of the transactions carried out over its own shares between 19 and 25 September 2024 (both inclusive).

The cash amount of the shares purchased to 25 September 2024 as a result of the execution of the Buy-back Programme amounts to 406,095,502 Euros, which represents approximately 26.6% of the maximum investment amount of the Buy-back Programme. The programme was announced together with its other characteristics through the Buy-back Commencement Communication.

Issuer name: Banco Santander, S.A. - LEI 5493006QMFDDMYWIAM13

Reference of the financial instrument: ordinary shares - Code ISIN ES0113900J37

Detailed information of the transactions carried out within the referred period is attached as Annex I.

Boadilla del Monte (Madrid), 26 September 2024

ANNEX I

Detailed information on each of the transactions carried out within the context of the Buy-back Programme between 19/09/2024 and 25/09/2024 (both inclusive)

(https://www.santander.com/content/dam/santander-com/es/documentos/cumplimiento/do-anexo-i-19-a-25-sept-2024.pdf)

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.