Welcome to the First Quarter 2026 Financial Results Conference Call and Webcast for Zoetis. Hosting the call today is Steve Frank, Vice President of Investor Relations for Zoetis. The presentation materials and additional financial tables are currently posted on the Investor Relations section of Zoetis.com. The presentation slides can be managed by you, the viewer, and will not be forwarded automatically. In addition, this call will be available approximately two hours after the conclusion of this call via dial-in or on the Investor Relations section of Zoetis.com. At this time, all participants have been placed in a listen-only mode, and the floor will be open for your questions following the presentation. If you would like to ask a question at that time, please press star 1 on your telephone keypad. If at any point your question has been answered, you may remove yourself from the queue by pressing star 2. In the interest of time, we ask that you limit yourself to one question and then queue up again with any follow-ups. Your line will be muted when you complete your question. When posing your question, please pick up the handset to allow optimal sound quality. It is now my pleasure to turn the call over to Steve Frank. Steve, you may begin.

Thank you, Operator. Good morning, everyone, and welcome to the Zoetis First Quarter 2026 Earnings Call. I am joined today by Kristen Peck, Chief Executive Officer, and Whitney Joseph, Chief Financial Officer. This morning, we issued a press release announcing our first quarter 2026 financial results. Before we begin, I would like to remind you that the release and corresponding earnings presentation, which we will reference during this call, are available on the Investor Relations section of our website, and that many of our statements today may be considered forward-looking statements, and that actual results could differ materially from those projections. For a list and description of certain factors that could cause results to differ, I refer you to the forward-looking statements in today's press release and in our company's reports filed with the SEC. Additionally, today's remarks will include certain non-GAAP financial measures. Reconciliations of these non-GAAP financial measures to the most directly comparable U.S. GAAP measures can be found in our earnings press release and our company's 8K filing dated today, May 7, 2026. We also reference reported and organic operational growth. Organic operational growth excludes the effect of foreign currency, as well as acquisitions and divestitures, which individually impacts OEDIS growth by 1% or more. Unless otherwise stated, all revenue growth performance metrics will be based on organic operational performance. And with that, I turn the call over to Kristin.

Thank you, Steve. Good morning, everyone, and welcome to our first quarter 2026 earnings call. I'll start with the headline numbers we reported today. On an organic operational basis, revenue was flat and adjusted net income grew 1%. Our international segment delivered 10% organic operational revenue growth, while the U.S. declined 8%. By species, livestock delivered 12% organic operational revenue growth, while companion animal declined 4% operationally. To level set, the quarter unfolded differently than expected, particularly in companion animal. We saw a convergence of interconnected dynamics, shaping decisions at the point of care. I'll outline each, along with their impact, and what we're doing about it. First, pricing in veterinary clinics continued to rise, though at a slower pace, adding to multi-year increases and lower clinic traffic. Second, pet owners demonstrated increased price sensitivity with softer demands for premium products in preventative and chronic care where Zoetis leads amid a more cautious spending environment. Third, competition intensified across key pet care categories, including dermatology and parasiticides with additional pressure in vaccines from certain generics. While competition is not new to us, what was different in Q1 was the pace and level of activity. More entrants across more markets with competitors leaning more heavily and aggressive pricing and incentives for extended periods of time to drive share, particularly in a softer end market. And fourth, In contrast to what we've seen historically, these new entrants have not yet translated into overall market expansion. Taken together, the result is a more price-sensitive and competitive environment. Pet owners delayed routine visits, extended dosing, and had new, lower-cost options, compounded by winter storms that further reduced clinic visits, all without the benefit of underlying market growth. As the market leader with significant share in premium products, we are at a point where our growth is less driven by new product cycles as we progress our blockbuster pipeline, which we expect to begin delivering significant value for the end of 27 and into 28. These dynamics increased our exposure, particularly compared to new entrants just launching into these categories and competing primarily on price. You see these dynamics most clearly in our key dermatology and Syparica franchises, where we saw declines in the quarter. In key dermatology, even with the industry's broadest and most differentiated portfolio, we were not able to fully offset the combined impact of increased owner price sensitivity and the lack of market expansion, which drove share pressure. That said, we do see a path for the market to return to growth over time, and we continue to invest in long-term growth while taking decisive near-term actions to compete more effectively. We also remain on track advancing Cytopoint Plus, which we expect will further strengthen our dermatology leadership. In Paraciticides, this Imperica franchise saw similar dynamics, but more pronounced in the U.S. Fewer patient visits drove lower prescription volumes and impacted new patient starts and compliance, with retail growth also moderating. Importantly, in the U.S., while competitive launches earlier in 2025 put pressure on share, largely through aggressive promotion, we saw that stabilizing, with share levels nearing prior year by quarter ends, and puppy share still well above our overall patient share. International markets continue to deliver strong growth in the quarter, supported by the ongoing geographic expansion of our portfolio, partially offsetting the U.S. Despite pressure on revenue, we are pleased with the improving U.S. share trends and our ability to maintain a leadership position in a more constrained market. And across both franchises, well, you can see these impacts geographically in today's results. This is more fundamentally about portfolio mix against the backdrop of the shifting demand trends I mentioned. Demand softness across key developed pet care markets underscores that this is not isolated, while emerging markets continue to provide runway for expansion. Now, turning to OA pain, while the broader trends for this category are consistent with what we saw in Durham and Paris, competitive dynamics are less of a factor here. In the quarter, Silencia continued to perform well, while Labrella drove the year-over-year OA decline. That said, sequentially, Labrella has stabilized in the U.S. with roughly flat growth. This U.S. stabilization reflects the continued execution across our multi-pronged strategy, with a strong emphasis on medical education and specialist engagement, which is helping build veterinary prescribing confidence. Findings, like those published by the Veterinary Medicines Directorate in the UK, confirming Labrella's positive benefit-risk profile are important inputs into the education efforts, and we saw an improvement in our conversations with vets in that market following the report. As mentioned on previous calls, we expect additional label updates. These are a normal part of the ongoing regulatory review and provide more information to support appropriate use. These are also in the early phases of our Lanivia and Portela launches in certain European markets and Canada, which will expand the OA pain franchise and support the long-term growth trajectory, and early feedback continues to be encouraging. Looking more broadly across companion animals, diagnostics continues to be a source of strength. Performance in the quarter was driven by strong international momentum with modest U.S. growth against a strong comparison period and slower placement activity. Expansion in reference labs drove performance alongside strength in chemistry and hematology with continued progress in images. This is consistent with the broader shift we see across pet care, where spending remains resilient in areas tied to urgent and diagnostic care. Turning to livestock, we again delivered broad-based performance. Underlying market conditions remained favorable with sustained protein demand, driving stronger producer profitability, and enabling continued investment in herd health and productivity. Performance was supported by our BIOS portfolio, particularly in cattle and poultry, where disease outbreaks and increased adoption reinforced the importance of prevention, alongside strong performance in fish, benefiting from favorable vaccination timing and in swine. As a result, livestock remains a strong source of growth with solid and market demand and a more focused portfolio following the MFA divestiture. Our performance this quarter underscores the value of our diversified portfolio, while also highlighting where we need to take action to maintain our leadership and regain momentum in pet care markets, where the consumer is under pressure and the competition is increasing. We are doing this on multiple fronts. First, we are sharpening execution across our core commercial levers with a clear focus on capturing demand more effectively. That starts with how we engage veterinarians, where we are focusing on integrated solutions that make better use of our broad portfolio and help strengthen clinic economics. We're also focused on improving execution in priority markets through localized action plans to more consistently convert demand into prescription. For pet owners, we're investing in targeted DTC activity, simplifying point-of-sale choices with clear loyalty and affordability options, and ensuring convenient, authorized access across clinics, retail, and home delivery. And in livestock, we're reinforcing continuity of supply and responsiveness in key products and markets, ensuring demand is not constrained by availability. Second, we're accelerating our science-to-scale model, shortening time from approval to launch and translating that into growth. That includes prioritizing near-term launches and advancing convenience-led lifecycle innovation with our portfolio that create new ways to compete, including long-acting MADS, PASERTA, and the recent Canadian approval of Convenia RTU, which expands access to a ready-to-use, cost-effective formulation. Third, we announced an agreement to acquire Neogen's animal genomic business, expanding our capabilities in livestock genetics. This reflects our broader approach to targeted business development, where we continue to be strategic in pursuing opportunities to unlock new sources of growth over time. Finally, we are sharpening our approach to capital allocation while continuing to invest in our key growth priorities. As reflected in our adjusted net income, we acted decisively as growth softened in the quarter and launched a comprehensive cost and productivity program, further tightening discretionary spending, driving procurement and operating efficiencies, and assessing organizational levers to deliver a leveraged P&L in 2026 and beyond. We have clear priorities and a proven track record of execution, and we are confident these actions will position us to better navigate the current environment and improve performance over time. Looking ahead, our focus is on improving our trajectory over the balance of the year. Zoetis is providing updated guidance based on the current operating environment and the presentation of its financials for fiscal year alignment. For the full year, on an organic operational basis, we expect revenue growth of 2 to 5 percent and adjusted net income growth of 2 to 6 percent. This quarter reflects pressure in parts of our container animal portfolio, where market growth has slowed and competition has intensified. As we bridge to Zuidas' next wave of innovation-driven growth, execution, commercial effectiveness, portfolio optimization, and enhanced golf discipline will play a greater role in driving performance, especially in this environment. We are actively managing through this period, and our conviction in the underlying strength of our business and what enables the lettuce to win has not changed. Animal health remains a durable and essential industry, underpinned by the strength of the human-animal bonds and sustained global demand for protein. We operate from a position of strength with leadership in the category we've helped build, a diversified portfolio across species, geographies, and channels, and the colleagues and capabilities to compete effectively in a dynamic environment. Our near-term focus is clear. Sharpen commercial execution and compete with precision while positioning the business to deliver the next wave of innovation we are doing this with a pipeline that includes 12 potential blockbusters and more than 7 billion in additional market opportunities as we extend our leadership into entirely new categories of care we have helped define the standards of care that exist today and we expect to play a leading role in what comes next as we deliver our next wave of innovation we've demonstrated our ability to perform in different environments and we will do so again and we remain committed to delivering long-term value for our shareholders

the executing with discipline today while continuing to invest in the innovation that will drive tomorrow's growth with that I will hand it over to working thank you Kristen and good morning everyone as Kristen highlighted our quarterly performance reflects multiple converging dynamics, macro-driven price sensitivity weighing on certain aspects of pet owner spending, ongoing pressure on vet clinic visits, and on increasingly competitive landscape in which price continues to be a key differentiator. These dynamics have led to performance that is below our expectations this quarter, but we are confident in our near-term efforts to drive demand and cost discipline, as well as our industry-leading portfolio and pipeline which we believe will continue to drive growth in the longer term now i'll walk you through our financial results for the first quarter which as a reminder are reflective of an aligned calendar year for the first quarter we reported global revenue of 2.3 billion dollars going three percent on a reported basis and flat on an organic operational basis with two percent growth coming from price offset by two percent decline in volume as we previewed last quarter, our Q1 2026 financial results were positively impacted by certain operational changes made in connection with our fiscal year alignment for subsidiaries outside of the United States. As referenced in our press release this morning and now posted under supplemental materials in the quarterly results section of our investor relations website, we have provided additional information in connection with our fiscal year alignment, including recast financial information on a quarterly basis for 2025 and annually for 2024 and 2025 to help with comparisons. You will note that for most quarters, the overall differences are relatively immaterial. However, I draw your attention to the $128 million revenue decrease on a recast basis from our previously reported Q4 2025 revenue. See the recast information on page 3 of the supplemental material. As we described last quarter, certain operational changes made in connection with our fiscal year alignment resulted in the acceleration of the timing of sales, which led to an approximate $30 million increase in the sales that we reported for our international segment for Q4 2025. The balance of the $128 million decrease in recast Q4 2025 revenue, or approximately $100 million, resulted in a corresponding increase in Q1 2026 sales in our international segment. This $100 million difference was driven by the change that we previously referenced in the timing of price increases in certain international markets and the delayed processing of customer orders that we referenced in our full year 2025 results, as well as by differences in the performance of the business when comparing Q4 2025 to a stronger Q4 2024. Excluding the approximately $100 million that shifted from Q4 2025 to early 2026 as a result of our fiscal year alignment, globally, we would have seen a 5% organic operational decline in the quarter. Adjusted net income of $646 million, good 2% on a reported basis, and 1% on an organic operational basis. Turning to our franchises, our global companion animal portfolio posted $1.5 billion dollars in revenue declining four percent the dermatology recorded three hundred forty seven million dollars in revenue down eleven percent versus the prior year consumer sentiment is pressuring aspects of pet owner spend in several key markets as we are facing increased competition globally for Applequil and despite our strong label twice has played a larger role in the decision process while cytopoint is also impacted by the vet claims dynamic as a For monoclonal antibody, with a longer duration of treatment, Cytopoint switching to recent JAKAI competitors has been low. Our OA pain maps, Librella and Salencia, posted a combined $140 million in revenue, declining 8%. Librella sales were $101 million, declining 13%. Librella trends have stabilized in the U.S., where we saw encouraging signs that our efforts are gaining traction. Valencia posted $39 million in revenue, growing 6%. Our Semperica franchise contributed $385 million globally, declining 1%. Semperica Trio declined 1% on sales of $297 million, while Semperica declined 3% on sales of $88 million. Additionally, we have seen recent generic competition impacting two companion animal products, Convenia, an antibiotic treatment for bacterial skin infections, and Serenia, the market-leading small animal, and Theomedic. While not considered part of our innovative core, these brands are both blockbusters and have lost meaningful share in the quarter due to price-driven generic competition. Our global companion animal diagnostics business posted $113 million in revenue, growing 10%, driven by expansion of our reference lab business, as well as growth in chemistry and hematology, driven by our recently launched Vetscan Opticelle. Moving on to livestock, which performed well in the quarter on $720 million in global revenue, growing 12%, with broad-based growth across geographies and species, as well as price and volume. Favorable producer economics drove higher demand, particularly in cattle. Combined with improved product supply and commercial wins, this provides solid foundation for sustained livestock growth, further supported by the long-term secular tailwind of rising global protein consumption. While our performance is driven by the declines in our companion animal business in the U.S. in certain developed markets internationally, this quarter highlights the benefit that having a global cross-species portfolio can have in challenging market conditions. Now, let's move on to our segment results for the quarter. U.S. revenue was $1.1 billion in the quarter, declining 8%. U.S. companion animal posted $865 million dollars declining 11 before going into our brand performance i wanted to highlight some of the broader impacts we've seen across our u.s pan animal business the global trends we have mentioned around competition and consumer price sensitivity are very prevalent in the u.s market additionally distributor and retail channel purchasing patterns were also a headwind this quarter reflecting the lower in market demand historically q1 distributor inventories start the quarter higher than they ended, as distributors typically buy ahead of price increases and promotions. This quarter, our promotions underperformed expectations and end-market demand softens, so distributors and retail partners took longer to work through their opening inventories and engaged in less replenishment activity. As a result, our sales into distributors and retail partners lagged their sales out to customers compared to prior year quarters. These overarching drivers have impacted much of our U.S. companion animal portfolio. Our key dermatology products posted $215 million in revenue, declining 13% in the U.S. Apple Coil has continued to face competitive headwinds, consistent with our expectations, with price remaining the primary differentiator, driving some shifts toward lower-cost alternatives. However, the impact has been more pronounced than we had expected. Share loss is being amplified by a dirt market with declining patient volume in the clinic. Unlike prior competitive cycles, we do not currently have the benefit of underlying market expansion to cushion the revenue effect of competitive share shifts. Though we do see a path for the market to return to growth over time with significant untreated and undertreated dogs in the space. Spider-Point trends were consistent with the global picture, primarily impacted by the vet planning dynamics rather than jack-eye competition. The U.S. Comparica franchise reported $238 million in revenue, declining 8% in the quarter. Comparica Trio posted $222 million in sales, declining 8%. Despite modest year-over-year declines due to additional entrants, our share has improved sequentially versus the second half of last year when we saw the impact of competitive launch promotions, which pressured our share, but also expended the triple accommodation market, a dynamic that is not providing the same market tailwind in the quarter. We continue to see market contraction with softness in the clinic driven by lower flea, thickened heartworm visits, as well as a slowing of alternative channel sales driven partly by script denials in retail. Our market-leading share in puppies remained stable. In the U.S., our OA pain maps also fixed $5 million, declining 15%. Librella contributed $37 million, declining 22%. U.S. Librella revenue increased sequentially for the first time in six quarters, and vet and pet owner satisfaction ratings remained stable. Additionally, despite declines in the canine OA pain market, our patient share has remained stable since the second half of 2025. Looking ahead, the comparative periods become more favorable as the year progresses, and combined with the stabilization we are seeing, we believe the underlying foundation of the business continues to strengthen. Valencia grew 2% in the quarter on $18 million in sales, with feline four-way visits holding relatively flat year-over-year. Generic competition in Convenia and Serenia also contributed to the U.S. companion animal Our U.S. lifestyle business posted broad-based wealth of 7% in the quarter, reporting $225 million in sales. We saw growth across all species, driven primarily by cattle on improved supply of seftifure, as well as the impact of strong demand generated from our spring promotions. Poultry and swine also delivered meaningful contributions, with poultry wealth driven by increased vaccine adoption and disease outbreaks, and swine benefiting from improved Moving on to our international segment for the quarter, revenue grew 17% on a reported basis and 10% on an organic operational basis, costing $1.1 billion in revenue. Excluding the impact of the previously noted $100 million in sales that shifted from Q4 2025 to early 2026 as a result of our fiscal year alignment, our international segment growth flat for the quarter. International Companion Animal reported $654 million in sales, growing 7%. The competitive and macroeconomic headwinds we have seen in the U.S. do exist in parts of our international business, but are largely concentrated in developed markets where conditions more closely resemble the U.S. environment. In many of our emerging markets, where the standard of care is still maturing, we believe that meaningful market expansion opportunities remain, and that distinction is evident in our international results this quarter. Our international Semperica franchise grew 14% on $147 million in sales. Semparica TRIO posted sales of $76 million, growing 29%, driven by key account plan nutrition in major markets and the benefit of our recent launch in Brazil. Semparica reported $71 million in revenue, which was flat on the quarter, impacted by conversion to TRIO in Brazil. Partially offsetting our growth in the quarter, Key Dermatology posted $131 million in revenue internationally, down 5%. For Apriquil, similar to the U.S., competitive pressures and macro price sensitivity, which are more pronounced in developed markets where Apriquil has a larger presence, are having a compounding impact on sales. Similar to the U.S., cytochrome performance is holding up better than Apriquil. Our OAPA maps posted $85 million in sales internationally, declining 2%. Librella reported $64 million in sales, down 7%. As Kristen noted, positive benefit risk findings have helped strengthen our medical education effort around Librella, and we have seen a meaningful improvement in our conversations with veterinarians. Valencia grew 10% on $21 million in sales. Additionally, our international small animal vaccines products grew 13% in the quarter, driven by increased usage of Felovacs in China. International livestock contributed $495 million with growth of 14%, with broad-based growth across all of our core species. We saw growth in cattle, swine, and poultry, driven by disease outbreaks, commercial wins, especially in vaccines, and improved supply. In fish, we continue to benefit from improved pricing on our Moatela vaccine, as well as volume growth from market expansion into the feral islands now let's move down the pnl adjusted gross margins of 71.8 percent declined approximately 10 basis points on a reported basis for an exchange had an unfavorable impact of approximately 150 basis points excluding fx we saw 140 basis point improvement in margins due to benefit from price and lower manufacturing costs partially offset by product and geographical mix. Adjusted operating expenses increased by 3% operationally due to higher compensation-related expenses, as well as increased freight and logistics costs. Adjusted net income grew 1%. Adjusted diluted EPS grew 7%, including a 3% benefit from our convertible debt-funded share repurchases. Now, moving on to guidance for the full year, 2026. Our updated guidance is reflective of the current operating environment as well as the presentation of our financials on an aligned fiscal calendar basis. When exchange rates used in our guidance are as of late April, we are revising our full year revenue guidance to a range of $9.68 to $9.96 billion with growth of 2% to 5% based on the current operating environment. It is worth noting that our fiscal year alignment was anticipated to provide approximately 200 to 250 basis points of tailwind to full year revenue growth. However, the challenging operating environment we experienced in Q1 and the expectations that carries for the remainder of the year more than offset that contribution. We now expect adjusted net income to be in the range of $2.87 to $2.95 billion with growth of 2% to 6%, reflective of the comprehensive cost and productivity programs Kristen mentioned Finally, we are updating our reported diluted and adjusted diluted EPS guidance ranges to $6.35 to $6.50 and $6.85 to $7, respectively. While Q1 reflected a more challenging environment than we anticipated, particularly in U.S. companion animal, where the convergence of price sensitivity lowered clinic traffic, and intensified competition was more pronounced than expected, our path forward is clear. We are taking decisive action to sharpen commercial execution and drive cost discipline. Looking ahead, while we have appropriately reflected the near-term environment in our updated guidance, we remain confident in the underlying strength of our diversified portfolio and our ability to deliver the next cycle of innovation-driven growth in the years ahead. We remain committed to delivering long-term value for our shareholders. Now, I'll hand things back to the operator for your questions. Operator?

Thank you. If you'd like to ask a question, press star 1 on your keypad. To leave the queue at any time, press star 2. Once again, that is star 1 to ask a question. And as a reminder, we do ask that you limit yourself to one question and then queue up again with any follow-ups. Your line will be muted when you complete your question. We'll take our first question from Michael Riskin with Bank of America. Your line is open.

Great. Thanks for taking the question. I'm going to throw a couple in here real quick. So one, Kristen, for you, just maybe a high-level, big-picture one. From what we see in the market, competition appears to still be at a relatively early point. We think it's only going to get worse from here. You've got a number of competing products that are still early in the launch cycle or haven't even launched yet at all. And, you know, with this increased competitive landscape, the macro consumer pressures, we think that's going to persist for some time, maybe as much as, you know, one or two years, if not longer. So when you talk about, you know, working through the challenges you're seeing, you know, you call out pipeline innovation as an offset. From what we can tell, some of the bigger product launches you have are still a couple years out. So what can you specifically do more in the near term to turn the ship around in the face of this growing competitive pressure and the consumer challenges? And then if I could squeeze in a second one real quick for more for Webney, you know, the math is a little bit messy given the calendarization impact. Maybe bear with me, but, you know, you called out the 200, 250 dips impact from calendar. For once you specifically, you know, you did zero organic under the new math, under the old calendar, maybe that comes out to something like down four or down five, given the 100 million benefit. And yet you're guiding to something like low single to mid single digit growth for the full year. That seems like a pretty aggressive ramp. You know, you've got easier comps in the second half. You do have the 4Q benefits in the calendar switch. But can you just bridge that for us? Is there anything else to factor in that will get you to that full year number after this 1Q print? Thanks.

Thanks, Mike. I'll start, and then Wetney can build on your second question. Essentially what we saw in the quarter was sort of the economic and sustained price increases that the pet owner has experienced in the clinic. This has obviously made them much more sensitive, but also, as you saw, led to a decrease in bed visits, especially in some of the key therapeutic areas that we're in, such as, you know, paras, OA pain, derm, et cetera. And I think this combined with an increase in price-driven competition. As, you know, people saw the pressure that the pet owners on, I think you saw more promotions and more, you know, price competition there. And really what that happened is that the market did not grow. Historically, as you've seen over the last few years, when we had competition increasing in Paris, the market grew. And I think, you know, what I think changes is that with new competition, we didn't see that market grow. I think the difference I think we might have with you as to what we see in the future is we are seeing positive trends. As Whitney and I mentioned in our remarks, if you look at Paris, for example, we have actually gained share from the end of last year into this year. And we ended the quarter, as we mentioned, pretty close to where we were last year before the competition entered. So, again, our focus will be on expanding the markets. But I think if you look at Paris, we're pleased at the progress that we continue to make there. We're also pleased with Librella. We saw stabilization of that product. As we look to the rest of the year, we continue to believe we can return that product to growth overall. Obviously, in the first half of the year, we have some tough comparable periods. But I think as we move through the year, we'll continue to gain share there and to grow. Obviously, in Durham, we do have to continue to see new entrants, but we think we have a strong differentiated portfolio there. We're also excited to be adding long-acting Cytopoint as we look to the end of the year. And look, we are sharpening our focus on execution and our commercial strategy. We're going to continue with veterinarians, leveraging the broad portfolio that we have and providing them integrated solutions to help capture share. We're going to focus with pet owners, as I mentioned, leveraging DTC to help broaden that market, but importantly, focus on affordability, which is clearly a major issue for them at the point of sale through loyalty and some affordability options we're providing. We'll also focus as well as retail and home delivery to optimize access there. So we think we've got a strong portfolio there that we can continue to build on. And I also don't want to undermine the strength that we saw in diagnostics and livestock in the U.S. and across the globe. But with that, what they'll turn it over to you.

Yeah, my thought, the first thing to really note here, and importantly, is that our initial guidance already contemplated some first half to second half dynamics. Now, clearly, the quarter ended up below our expectations. But this dynamic around the persistence of competition and macro is something we contemplated and we are seeing. And so we expect those to continue in the guidance that we give today. But to the point Kristen just raised, we do see stabilization in a number of areas, including Nibrella. With our already paying franchises, we are launching our long-acting products in a couple of markets, and a few markets here in the quarter as well, and across our Semperica franchise and so forth. Now, as we noted in our prepared commentary, you heard that this in-market demand softness also caused purchasing patterns to be a headwind for us in the quarter. But we ended the quarter at a level that we believe is also normalized for how we go from here versus being a headwind, given they ordered less during the quarter than they were shipping out to clinics. So with those and the actions that we are taking, we have widened the range and the guidance, given we do see a remaining uncertainty in the markets that we operate, but we're also executing against those, hence the guidance that we have issued today.

We'll move next to Erin Wright with Morgan Stanley. Your line is open.

Great, thanks. I want to dig into that a little bit more. So, what does guidance imply now for the quarterly progression for companion animal? I guess, you know, given the implied ramp here, you know, even backing out the easy realignment comp in the fourth quarter, which is about a point, like, you know, are you baking in some distributor or retail then restock? Is that what you're implying after the destock? And why is that just given the increasing competition? And how much of a headwind was that in the quarter and were there significant changes in purchasing patterns, I guess, at retail as well? You mentioned script denials. Can you talk a little bit more about that? And that's now going back to their typical conflicts of interest there with online scripts and denying scripts there. And can you clarify a little bit more about what we're lapping here from last year in terms of stocking and de-stocking dynamics, because I want to make sure just we're aware, given some of the unforeseen dynamics in the current quarter on stocking, de-stocking dynamics, and how much you're leveraging the channel, you know, and I guess one bigger picture question just on guidance as well, you know, you talk about the 200 basis point benefit from the accounting change now embedded in the guide. I just want to confirm one point of that will not recur in 2027, right? So, as we think about 2027 and beyond, how do you kind of mitigate that, and when could we get back to, you know, your typical 68 percent operational revenue growth?

Sure, Erin. Look, we're certainly unpacking the guidance starting with companion animal, then we'll get to your bigger picture question in terms of comps going into 2027. We are not embedding an assumption that inventory picks up in terms of the level of inventory that is in distribution. We typically don't do that. As you may recall, you've been around with us for a long time. In 2023, we saw quite a step down in terms of level of inventory that distributors take. We have not assumed that those would come back into the channel, and they have not. We've been operating at a range that is well below where we were pre-2023, and within that range, we're now operating at the low end of that new range, if you follow, as we exit the first quarter of 26. So we are not baking in some rebound in that. It is reflective of what the end market demand has been, and it's reflected in the performance that we shared today with respect across our key franchises. And so what we are embedding here, and by the way, we are also assuming headwinds related to competition that is to launch and continued pressure in terms of what we're seeing from a competitive and macro perspective. And so the script denials have been an impact as we look at retail. Retail continued to grow faster than the clinic, though, but not at the rate that it had been over the last couple years. If you go back to last year and the year before, you were seeing retail growth somewhere in the 25% to 30% range. That growth rate in retail is in the low double digits as we look at this quarter, somewhere in the 10% or so range in retail. So clearly a step down, and part of that is what we're seeing in terms of script denials. Again, we're not assuming those necessarily come back. it's really the actions that we're taking to drive commercial execution as well as the easier comps that we face as we get into the back half of the year that's playing here now we won't get ahead in terms of what 2027 looks like clearly the 200 to 250 basis points that we're talking about is a combination of coming into q1 and then what is the the q4 comp is versus the prior year and so that will clearly be a hit when you go into 2027 all else being equal however we are executing to what the market is showing, both in the top line to drive performance there, as well as the bottom line, which is why you see a guidance that shows leverage through the P&L down to the bottom line.

We'll take our next question from Brandon Vasquez with William Blair. Your line is open.

Hey, thanks for taking the question. Maybe I can start with a high-level question. Kristen, you were talking a lot about kind of the headwinds you guys are seeing from a macro perspective, right? Let's just ignore some of the competitive and company-specific issues, but we're talking about price being a lever here. We're talking about markets not expanding. We're talking about more competition, even generic competition. These are all very uncharacteristic, I think, of what this market historically used to be. It used to be resilient. It used to take price. It used to not really have a lot of generics, and it used to be powered by brand. And so the question being, it feels like what you're describing is entering a new world in this market, one that maybe is less durable and less attractive for zoetis. Is that true? What is, I mean, clearly you guys are assuming something improves. What is it that's giving you hope that this kind of reverses back into the old animal health market we used to know?

Sure. I mean, for starters, I'd say, look, the demand for veterinary care remains structurally very strong, given the importance of the human-animal bond and the large number of untreated populations. You know, that's clear. If you look, and as I mentioned in my prepared remarks, we're continuing to see strength in urgent care, and we're continuing to see strength in diagnostics and areas like that, which says to me the pet owner still wants to get care. I think they're in a period where they're a little bit struggling with the price increases over the last few years. We ultimately believe that will stabilize. I think that clinics are really trying to address that and trying to get the pet owners back in. As, you know, us and others have mentioned, we saw about 3% growth of revenue in the clinic, but that was all driven and continued by price, with clinic visits down about 3%. Ultimately, that will stabilize. We firmly believe that. We're also really optimistic, as we've seen, of the sequential trends we've seen in areas like OA pain and in Paris. You know, we think that the strength of our portfolio, the differentiation, the innovation we provide will endure. I don't think we're moving to a world of generic. We are not expecting generics in any of our key categories. We're not expecting it in DERM. We're not expecting it in pain or in Paris in the near term. So for the next, you know, many years, we will not see that. There certainly, as we saw in, you know, Serenia and Convenia, which are blockbuster products, you know, but not ones we talk about. We did see some increased competition from generics there. The competition we see today is not generic in our major therapeutic areas. It's products that, you know, have launched in categories we've been in for a while. We ultimately believe some of these price-driven promotions will stabilize over time. And we also believe the differentiation I think we have with our portfolio, the strength of our brand, and importantly, the strength of the service we provide veterinarians will endure. So no, I don't see it the way you do. I think innovation matters. I think the service we provide matters. And I think ultimately, given the strength of the human-animal bond and the structural demand for veterinary care, this will stabilize over Okay.

We'll take our next question from Chris Scott with J.P. Morgan. Your line is open.

Great. Thanks for the questions. Just two for me. Can you just comment on your latest assumption around pricing this year, given some of the comments you're making around the promotion activity you're seeing? Is that something you're reacting to on price on your side, or is that more we should be thinking about share loss? And the second question, sorry if I missed this in the remarks, but when I think about U.S. companion growth and what's reflected in guidance, can you just talk a little bit about how we should be thinking about growth for this year? I know you're assuming recovery from the down 12% this year with livestock driving growth, or do you think this is a business that can kind of get back to flat or growing as we go through the year? Thank you.

Sure. I'll start on the price one, and then Whitney can take the guy. Right. As we've always said, we are not planning to compete through price as our main strategy. Our focus, as always, will remain on our differentiated portfolio, the breadth of it, the service we provide and execution. We are a premium innovative brand, and that is not going to change. We did take price, as you saw in the quarter. I think we can continue and what we can talk where it is relative to historic price challenges. Obviously, in areas where we've seen generic competition. We have taken selective price actions there. We'll obviously continue to leverage promotions. But our priority remains innovation, differentiation, and service to our customers. And we continue to believe we can take price, albeit maybe at lower levels of right now, given the challenge we're facing right now. But I'll let Whitney put that into perspective and also talk about an impact on the guy.

Chris, as you know, we don't typically provide guidance down to the species, but I would share a couple of things that I think might be helpful for Just keep in mind, we are running a global diversification business with companion animal both in the U.S. and outside the U.S., and in the quarter, our international segment, companion animal grew 7%. I would add also, given the dynamics that we described and the headwinds of those created in the quarter, including how distributors, order pattern, and retail had a more pronounced effect on the first quarter. We do see stabilization across companion animals as we go with the key franchises. And what we're saying now is we expect our key franchises to grow in the low to mid-single digits, which is a step down from what we said when we initially issued guidance. And so when you take all that into consideration, yes, we do expect livestock continue to drive momentum here. I would put livestock in the mid to high single-digit growth range for the year, But the balance would be growth across companion animals without getting into specifics on guidance.

We'll move next to John Block with Stiefel. Your line is open.

Thanks, guys. Good morning.

Maybe just the first one. You know, Wendy, I believe you said the channel's now normalized. You know, I do think that U.S. pet health number surprised everyone. So, is there a way of calling out the impact in 1Q26 from the channel, what that was specific to U.S. Pet Health. And then, Kristen, just, you know, to back up at a higher level, I'm just trying to dig in on the competitive response, and maybe I was a little confused. So, is anything changing from Zoetis among your approach to call it the atopic derm or the trio franchises regarding price? If it's not sort of unilateral, are there any targeted promotions or no? Because it seemed like you acknowledge the consumer wants a cheaper alternative or is looking for that. And then I was a bit confused if Zoetis is pivoting there and trying to deliver on that or just really focus on the bundling and the services. Thanks.

Yeah, perhaps, John, I'll take the normalization point around inventory. Clearly, it is, I would say, difficult to separate out the macro and the soft in-market demand versus what the patterns are and what distributors and retailers did in terms of adjustments. Again, they ordered less from us than they were shipping out to customers, given the software in-market demand and promotions that did not execute to the level that we expected coming into the year, right? And so that certainly had a pronounced impact, but I would put that back to the macro and the competitive dynamics that we're seeing and the impact it has in terms of in-market Sure, John, and I'll build up the second part of your question.

And, you know, my point is we're not overall lowering our list price and products. We continue to run promos, as we always have, you know, seasonal promos for paras. We can do cross-portfolio promos in the United States, you know, leveraging, you know, both, you know, DERM and other categories. But I think what I was really focusing on is addressing the affordability issue, which is actually a pet owner. That's not what we sell into the vet. It's the pet owner at point of sale. We've always had loyalty programs, as you know. But those loyalty programs are, you know, you scan your receipt and then you get a cashback card to spend later. You know, given the affordability issue that is more urgent, we're looking at more point-of-sale loyalty programs, more ability to deal at point-of-sale with the challenges the pet owner may be having economically. So our real focus there is not as much on the vet, but on the pet owner issue.

We have these programs today, but as I said, we're looking to alter them to make sure we can do that more at point-of-sale versus just over time you know where they can use it you know in a month or two etc we're really trying to make sure we address that with programs both in the united states and across the globe we'll move next to steve to share with keybank your line is open hey thanks for the question i guess just first um on price sensitivity is that is that still limited to the gen z and millennial age groups or is that spread more into other age groups now and then just on Lanivia as you move closer to U.S. launch next year. How tied is the performance of that drug? Do you expect it to be tied to Labrella? Or should we view those as two completely separate products? Thanks.

Sure. So I'll start with your question with regards to Lanivia. With regards to Lanivia, we did get approval in certain markets in the EU and in Canada, and we just launched that product. So we look forward to having more information on how that launch is going as we go into the next quarter. You know, as we talked about, this is not long-acting, Librella. We think the efforts, the multi-prompt strategy we've been executing across OA pain, really focusing on awareness that treating OA pain as a serious condition is important, making sure we spend time with vets and specialists understanding OA pain will continue to be important. Also making sure we share the science and the positive experience that many of our customers have and investing in that phase four research. We think building this understanding of OA pain will be important as we launch long-acting. Certainly, that's what we're experiencing right now in certain markets in the EU and in Canada. And we think that long-acting provides, again, to the issue that pet owners are having on just, you know, convenience as well as affordability, a great new option. So, we're excited for that. I think you asked a second question with regards to demographics on Gen Z and millennials. I mean, I think affordability is more based on the economic situation that a pet owner is in. It's not just based on age, to be honest. So we're really targeting the affordability issue, not at generations, but just as pet owners overall who are facing those challenges.

And we'll move next to Navon Tai with BNP Paribas. Your line is open.

Thanks for taking my question. A follow-up on the pricing strategy. So you discussed the pricing against that price sensitivity. And I'm also curious of your pricing strategy to defend against the competitive pressure in derms, which is further intensifying, and also your pricing strategy for your upcoming innovation in renal oncology and cardiology if that price sensitivity environment is maintained. And then I have a second question on DERM specifically, because we are seeing that the competitor has raised prices on the jack. So would you say that the competition is now not only on price, but also some efficacy and frontline users? Thank you.

Sure, Navan, I'll take your question on pricing strategy. And look, the way we approach pricing is always down to each market, each product, and what What is the value that we're bringing and what is the competitive landscape at the time? And as Christian referenced earlier, we now have an aggregate price expectation. This is not by product, of course, for the company that's in the 1% to 2% range when we started the year at 2% to 3%, and we've been higher than the last couple of years. So clearly, we have adjusted our expectations, not getting down to specific pricing actions and strategy on a specific product for competitive reasons here on this call. But certainly, we are taking those into consideration. And as we launch new products, which we do extensive market research on prior to launch, we, of course, will be looking at what is the value that we're bringing in clinically and what is the willingness to pay for that, which we continue to see sustaining across the industry. So that will be what we'll put into place. In terms of competitors' prices, as you've said, historically, we've seen competitors come in with list prices that are somewhat slightly below where ours are, but with aggressive promotions initially to get the products uh embedded into clinics um and so forth so we've certainly seen that uh the price and seriously in the market is translating to that uh lasting longer i would say than we've seen historically but they are in many instances and include you reference one are raising prices well above where we're raising it still remains that there's a gap between where our pricing is versus where theirs is but it is closing in effect and so we'll continue to monitor those, but also executing on our actions against those, including the breadth and strength of our portfolio.

We'll move next to Daniel Clark with Larynx Partners. Your line is open.

Great. Thank you. Also wanted to ask about the 2026 updated guide. How are you thinking about the macro and sort of competitive intensity as we head through the year? Should we expect similar levels of both, you know, as we saw in one Q, you know, through the rest of the year. I guess, how are you thinking about that? And then, secondarily, I just wanted to quickly ask, how did—how much did Q DERM grow ex-US if we strip out any of the alignment impacts? Thank you.

Sure. In terms of our expectations on the macro, we are expecting that to persist. And so, we're not expecting a rebound nor significant deterioration in terms of what the macro looks like. We've seen the impact that it has both in terms of in-market demand and then therefore directly impacts to where distributors and retailers are replenishing their inventory levels, which created the headwind for us. And so that's the answer on that one. In terms of Keep Durham and what the implications might be related to FYA, we have not broken those down to individual products or individual markets to be able to get to that level. We believe we've been very helpful in our comments, which is what the overall impact is and what we would have expected to be the guidance impact, which is around 200 to 250 basis points lift in our guidance, and clearly given the performance we've seen and the persistence that we're expecting in the macro and competitive dynamics, that has not come to fruition in the guidance that we're given today.

We'll move next to Andrea Alfonso with UBS.

Your line is open. hi good morning guys um i just have a quick question um around margins so um on gross margins you did 71.8 this quarter and it looks like your updated guidance calls for you know 71.5 for the full year i i know you don't provide quarterly guidance but you know just sort of looking at the trajectory for the remainder of the year it does look like you're lapping a pretty tough Compton 2Q. I guess more broadly, how do you think about that trajectory and sort of frame the letters that you have at your disposal to deliver there, you know, given that pressure on, you know, some of your higher gross margin products? And then if I could squeeze in a separate housekeeping question, if you could just confirm that the 2 to 5 percent revenue growth outlook constant currency does not include any benefit from Neogen potentially closing in the second half. Thanks so much, guys.

Sure. I'll take both of those. If you look at our gross margins in the quarter, they were down about 10 basis points. But if you strip out the impact of FX, they're actually up about 140 basis points. So we have been very pleased with the execution across our manufacturing enterprise. and certainly you see that reflected in our performance in the quarter. We will continue to drive actions across the company, including in this segment, that will contribute to the performance for the year and the leverage that we have on the P&L. Do keep in mind that the mix in terms of products is an element to consider here. As you've seen in our guidance, and as I shared just a moment ago, We expect livestock continue to drive momentum here and grow faster than companion animal. There is some mixed impact to that with respect to what you see in gross margins. And in terms of effects, you've seen the U.S. dollar impact in terms of revenue, but that has some converse effects when you get down to cost of sales. So that is a consideration here as well in terms of where you're comparing in terms of comps as we go through the rest of the year. But very pleased with the performance in terms of what we're doing on cost of sales. despite the mix that we see in some geographical implications as well. With respect to the guidance range on two to five, we do take a number of factors into consideration, including when competitive launches are going to come in, how aggressive they'll be. And so that range, which we widen by a point here for the uncertainty associated with those is in here. And so within the guidance range, you could have the impact of potential, the closing of the deal with Neogen within that range.

We'll move next to Steve Scala with TD Cowan. Your line is open.

Hi, this is Chris. I'm for Steve Scala. Thank you for taking our questions. First, what is Zoetis' level of interest and confidence in FTC approval of large-scale transformational business development? And second, do you see any opportunity to significantly pull forward large timelines designs for products for new markets like renal and oncology, e.g. by changing trial designs or filing based on surrogate endpoints? Thank you.

So sure, let me start with your BD question. You know, as always, our focus is on incremental BD. We don't see transformational BD as a major strategy for the company. As we've spoken about before, from a capital allocation perspective, first and foremost, we are investing in our business. We obviously will continue to look at business development, and I think Neogen is a great example where we think there's incremental technologies or additional portfolios, such as what we've done in Australia for sheep, et cetera. So we'll continue to look for that. You should not expect large transformational BD. I think the deal like Neogen is what our sweet spot has historically been and will continue to be. Is there a second part of your question? I think we're good.

Just on launch timelines and potential to pull forward filings for some of the newer market products.

Sure. You know, we're always focused as we think about our pipeline of, you know, how we can pull forward. I would say anything that you see in the next few years is already in clinical trials. We're certainly partnering with the FDA, myself and the other industry leaders, to look at ways to speed innovation and to find new innovation pathways with the FDA. We're certainly leveraging AI, as I've spoken about before, within our portfolio, both in discovery, research, development, and importantly, preparing our dossiers for submission. We think all that can certainly speed it up. And we're also focused on, once we get approval, how we can speed time from approval to in-market across our portfolio.

Thank you. At this time, we've reached our allotted time for questions. I'll now turn the call back over to Kristen for any additional or closing remarks.

As always, everyone, thank you for your questions and your continued interest in Zoetis. I do want to recognize before we close our colleagues around the world whose commitment to their customers and their resilience has really helped us navigate this environment. We will continue to keep you updated on our progress and our priorities. We are focused on executing with discipline to position the business to return to growth, and we remain committed to delivering long-term value for our shareholders. Thanks so much for joining us today.

Thank you. This brings us to the end of today's meeting. We appreciate your time and participation. You may now disconnect.