Tekla Capital Management LLC

CIK

1300336

Location

BOSTON, MA

Portfolio Value

Mid $2,445,141,979

Diversification

Diversified

Filing Date

Global Rank

#989 / 7,034 ▼ 79 · as of Jun 2023

Top Industry

Drug Manufacturers - General 35.6%

Period ended 3 years ago

Filed Aug 10, 2023 · 3y

14 quarters · since Mar 2020

Regulatory profile

From Form ADV, the SEC filer profile, 13D/13G type codes and N-CEN, never from the name.

Holder type

Unknown

Portfolio style

Measured from the filed 13F common-share book for Jun 30, 2023, never from the firm's own description.

Style

Diversified active

Top 10 weight 42.1%, 40.4 effective positions, active share 86.5% against the Dow Jones Industrial Average as of 2023-07-31; it meets none of the index-like, systematic-like or concentrated tests

Turnover

Medium turnover

36.2% over the last four quarters (30% to under 100%)

Horizon

Long horizon

Value-weighted holding period 12.9 quarters (12+), a floor since 85.5% of the book was already held when coverage starts

Closest benchmark: the Dow Jones Industrial Average as of 2023-07-31, active share 86.5%; sector active share 81.9% against the combined 13F book's sector weights.

Over time 14 measured quarters

How the bands are measured

Style bands measure the filed 13F common-share book each closed quarter, tested in this order. Unknown: under $10,000,000 of valued equity or 5 stocks. Index-like (100+ stocks): active share of 20% or less against the closest benchmark, which is the S&P 500, S&P MidCap 400, S&P SmallCap 600, Russell 1000, Russell 2000, Nasdaq-100 or Dow Jones Industrial Average (weighted by an index-tracking fund's reported holdings or the index's constituents nearest the quarter end, over the names resolved to companies, and only when those are 90%+ of its weight) or every 13F filer's combined book, or index series holding 80%+ of the registered fund assets it advises (N-CEN) and equal to 50%+ of its book. Systematic-like: 500+ stocks, 100%+ annual turnover and a top 10 weight of 25% or less. Concentrated: a top 10 weight of 60%+ or 12 or fewer effective positions. Diversified active: none of these. Turnover is the smaller of buys and sells over average equity value, summed over four quarters: low under 30%, high 100%+. Horizon is the value-weighted number of quarters each position has been held: short under 4, long 12+.

Clone Performance

Build a hypothetical price-return history from this filer's public 13F holdings.

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Portfolio Concentration

157 tracked positions · as of Jun 30, 2023 · Δ vs Mar 31, 2023

Top Position

5.6%

+0.3 pts

Top 5

24.6%

+0.7 pts

Top 10

42.1%

+0.8 pts

HHI

247

Diversified+2

Portfolio Trend

14 quarters · across all stocks

Sector Breakdown

As of Jun 30, 2023

Sector	% Portfolio	Value	Positions
Healthcare	94.2%	$2,302,394,595	122
Unclassified	4.2%	$102,316,614	23
Real Estate	1.7%	$40,430,770	12

Last Quarter's Activity

Export CSV

Jun 30, 2023 vs Mar 31, 2023

Added To

Positions the filer increased

25 positions

Ticker	Company	Δ Shares	Shares	Value
BAX	Baxter International Inc	+257,058	324,370	$14,778,297
IMVT	Immunovant, Inc.	+220,800	336,200	$6,377,714
FULC	Fulcrum Therapeutics, Inc.	+198,351	256,888	$847,730
PCVX	Vaxcyte, Inc.	+189,232	194,232	$9,699,946
MRK	Merck & Co., Inc.	+176,032	728,154	$84,021,690
BSX	Boston Scientific Corp	+91,800	657,790	$35,579,861
—		+67,363	150,863	$0
AMGN	Amgen Inc	+60,600	616,539	$136,883,988
IQV	Iqvia Holdings Inc.	+46,012	109,129	$24,528,925
LIVN	LivaNova PLC	+44,600	108,480	$5,579,126
—		+38,124	173,248	$15,782,893
DHR	Danaher Corp	+37,123	142,813	$34,275,126
ABBV	AbbVie Inc.	+34,030	545,629	$73,512,595
TCMD	Tactile Systems Technology Inc	+24,040	58,472	$1,457,706
MDGL	Madrigal Pharmaceuticals, Inc.	+21,953	34,434	$7,954,254
MRNA	Moderna, Inc.	+21,478	343,695	$41,758,942
EW	Edwards Lifesciences Corp	+18,451	189,597	$17,884,685
REGN	Regeneron Pharmaceuticals, Inc.	+18,365	161,418	$115,985,289
MEDP	Medpace Holdings, Inc.	+17,483	26,918	$6,464,896
—		+16,400	34,250	$3,492,130
ASND	Ascendis Pharma A/S	+15,000	138,791	$12,387,096
NVO	Novo Nordisk A S	+11,454	122,777	$19,869,001
SYK	Stryker Corp	+9,550	81,128	$24,751,341
BIIB	Biogen Inc.	+7,017	247,943	$70,626,563
TMO	Thermo Fisher Scientific Inc.	+5,282	98,987	$51,646,467
No positions match the current search.

Trimmed

Positions the filer reduced

25 positions

Ticker	Company	Δ Shares	Shares	Value
QURE	uniQure N.V.	−296,166	356,280	$4,082,968
BMY	Bristol Myers Squibb Co	−205,298	458,498	$29,320,947
PFE	Pfizer Inc	−150,600	1,624,476	$59,585,779
GH	Guardant Health, Inc.	−126,100	346,084	$12,389,807
—		−112,332	112,331	$21,619,224
SRPT	Sarepta Therapeutics, Inc.	−106,216	179,437	$20,549,125
BMRN	Biomarin Pharmaceutical Inc	−89,300	210,789	$18,271,190
CI	Cigna Group	−86,292	96,339	$27,032,723
ACHC	Acadia Healthcare Company, Inc.	−85,575	100,912	$8,036,631
LLY	ELI LILLY & Co	−75,565	213,352	$100,057,820
ABT	Abbott Laboratories	−71,400	552,455	$60,228,644
—		−45,679	411,101	$4,464,557
EWTX	Edgewise Therapeutics, Inc.	−44,607	150,418	$1,165,739
BCYC	Bicycle Therapeutics PLC	−44,338	44,338	$1,131,505
—		−40,936	131,435	$8,322,464
RMD	Resmed Inc	−38,485	34,704	$7,582,824
CRSP	CRISPR Therapeutics AG	−32,509	22,571	$1,267,135
ISRG	Intuitive Surgical Inc	−28,700	83,980	$28,716,121
UNH	Unitedhealth Group Inc	−27,212	206,961	$99,473,735
GILD	Gilead Sciences, Inc.	−26,000	1,533,884	$118,216,439
NTRA	Natera, Inc.	−24,636	24,636	$1,198,787
ARGX	Argenx SE	−22,757	65,553	$25,547,970
UTHR	UNITED THERAPEUTICS Corp	−19,735	41,465	$9,153,398
XENE	Xenon Pharmaceuticals Inc.	−16,208	67,506	$2,598,981
VRTX	Vertex Pharmaceuticals Inc	−12,300	318,043	$111,922,512
No positions match the current search.

New Positions

Positions the filer opened this quarter

9 positions

Ticker	Company	Shares	Value
PODD	Insulet Corp	43,847	$12,642,843
THC	Tenet Healthcare Corp	149,070	$12,131,316
—		72,425	$7,448,911
INSP	Inspire Medical Systems, Inc.	22,018	$7,147,923
—		61,497	$2,871,295
AMLX	Amylyx Pharmaceuticals, Inc.	104,007	$2,243,430
XNCR	Xencor Inc	56,675	$1,415,174
ZNTL	Zentalis Pharmaceuticals, Inc.	40,156	$1,132,800
—		27,000	$464,130
No positions match the current search.

Sold Out

Positions the filer fully exited

18 positions

Ticker	Company	Shares	Value
TVTX	Travere Therapeutics, Inc.	418,520	$9,412,514
LNTH	Lantheus Holdings, Inc.	79,495	$6,563,107
—		682,834	$5,872,372
—		50,538	$5,423,738
—		68,949	$5,071,199
ADUS	Addus HomeCare Corp	42,380	$4,524,488
—		174,859	$3,472,700
KURA	Kura Oncology, Inc.	283,281	$3,464,526
—		49,406	$3,246,468
—		67,710	$3,046,273
RARE	Ultragenyx Pharmaceutical Inc.	67,065	$2,689,306
ARWR	Arrowhead Pharmaceuticals, Inc.	100,422	$2,550,718
SNDX	Syndax Pharmaceuticals Inc	117,717	$2,486,183
ALGN	Align Technology Inc	6,925	$2,313,919
OPCH	Option Care Health, Inc.	64,975	$2,064,255
—		69,025	$1,270,060
ZLAB	Zai Lab Ltd	34,640	$1,152,126
BHVN	Biohaven Ltd.	35,087	$479,288
No positions match the current search.

Portfolio Positions

Compact Export CSV View 13F filing

157 tracked positions · $2,445,141,979 total · filing declares 166 positions · $2,555,383,183 · as of Jun 30, 2023

All sectors Healthcare Real Estate

Showing 1–50 of 157 positions by value · page 1 of 4

Ticker	Company	Type	Shares	Δ Shares	Value (USD)	% Δ Value	Held (qtrs)	Est. cost/share	% of Portfolio
AMGN	Amgen Inc Healthcare	Added	616,539	+60,600	$136,883,988	+1.8%	14+	before history	5.60%
JNJ	Johnson & Johnson Healthcare	Held	721,779	0	$119,468,860	+6.8%	14+	before history	4.89%
GILD	Gilead Sciences, Inc. Healthcare	Reduced	1,533,884	-26,000	$118,216,439	−8.7%	14+	before history	4.83%
REGN	Regeneron Pharmaceuticals, Inc. Healthcare	Added	161,418	+18,365	$115,985,289	−1.3%	14+	before history	4.74%
VRTX	Vertex Pharmaceuticals Inc Healthcare	Reduced	318,043	-12,300	$111,922,512	+7.5%	14+	before history	4.58%
LLY	ELI LILLY & Co Healthcare	Reduced	213,352	-75,565	$100,057,820	+0.8%	14+	before history	4.09%
UNH	Unitedhealth Group Inc Healthcare	Reduced	206,961	-27,212	$99,473,735	−10.1%	14+	before history	4.07%
MRK	Merck & Co., Inc. Healthcare	Added	728,154	+176,032	$84,021,690	+43.0%	14+	before history	3.44%
ABBV	AbbVie Inc. Healthcare	Added	545,629	+34,030	$73,512,595	−9.8%	14+	before history	3.01%
BIIB	Biogen Inc. Healthcare	Added	247,943	+7,017	$70,626,563	+5.4%	14+	before history	2.89%
ILMN	Illumina, Inc. Healthcare	Reduced	336,979	-11,100	$63,180,203	−21.9%	14+	before history	2.58%
ABT	Abbott Laboratories Healthcare	Reduced	552,455	-71,400	$60,228,644	−4.7%	14+	before history	2.46%
PFE	Pfizer Inc Healthcare	Reduced	1,624,476	-150,600	$59,585,779	−17.7%	14+	before history	2.44%
TMO	Thermo Fisher Scientific Inc. Healthcare	Added	98,987	+5,282	$51,646,467	−4.4%	14+	before history	2.11%
ELV	Elevance Health, Inc. Healthcare	Held	114,070	0	$50,680,160	−3.4%	14+	before history	2.07%
MRNA	Moderna, Inc. Healthcare	Added	343,695	+21,478	$41,758,942	−15.6%	14+	before history	1.71%
BSX	Boston Scientific Corp Healthcare	Added	657,790	+91,800	$35,579,861	+25.7%	14+	before history	1.46%
DHR	Danaher Corp Healthcare	Added	142,813	+37,123	$34,275,126	+28.7%	14+	before history	1.40%
MDT	Medtronic plc Healthcare	Reduced	344,417	-100	$30,343,137	+9.2%	14+	before history	1.24%
IDXX	Idexx Laboratories Inc Healthcare	Held	58,595	0	$29,428,166	+0.4%	14+	before history	1.20%
DXCM	Dexcom Inc Healthcare	Held	228,747	0	$29,396,276	+10.6%	13	$89.67	1.20%
BMY	Bristol Myers Squibb Co Healthcare	Reduced	458,498	-205,298	$29,320,947	−36.3%	14+	before history	1.20%
ISRG	Intuitive Surgical Inc Healthcare	Reduced	83,980	-28,700	$28,716,121	−0.2%	14+	before history	1.17%
ALNY	Alnylam Pharmaceuticals, Inc. Healthcare	Held	143,214	0	$27,202,067	−5.2%	14+	before history	1.11%
CI	Cigna Group Healthcare	Reduced	96,339	-86,292	$27,032,723	−42.1%	14+	before history	1.11%
MCK	Mckesson Corp Healthcare	Reduced	61,955	-4,500	$26,473,991	+11.9%	14+	before history	1.08%
ARGX	Argenx SE Healthcare	Reduced	65,553	-22,757	$25,547,970	−22.4%	14+	before history	1.04%
HCA	HCA Healthcare, Inc. Healthcare	Reduced	82,403	-6,300	$25,007,662	+6.9%	14+	before history	1.02%
SYK	Stryker Corp Healthcare	Added	81,128	+9,550	$24,751,341	+21.1%	14+	before history	1.01%
IQV	Iqvia Holdings Inc. Healthcare	Added	109,129	+46,012	$24,528,925	+95.4%	14+	before history	1.00%
ZTS	Zoetis Inc. Healthcare	Held	136,914	0	$23,577,959	+3.5%	14+	before history	0.96%
CRL	Charles River Laboratories International, Inc. Healthcare	Reduced	111,183	-6,900	$23,376,225	−1.9%	14+	before history	0.96%
		Reduced	112,331	-112,332	$21,619,224	−52.5%	11	unpriced	0.88%
SRPT	Sarepta Therapeutics, Inc. Healthcare	Reduced	179,437	-106,216	$20,549,125	−47.8%	14+	before history	0.84%
NVO	Novo Nordisk A S Healthcare	Added	122,777	+11,454	$19,869,001	+12.2%	14+	before history	0.81%
MOH	Molina Healthcare, Inc. Healthcare	Held	61,856	0	$18,633,501	+12.6%	13	$247.25	0.76%
JAZZ	Jazz Pharmaceuticals plc Healthcare	Held	147,779	0	$18,320,162	−15.3%	14+	before history	0.75%
BMRN	Biomarin Pharmaceutical Inc Healthcare	Reduced	210,789	-89,300	$18,271,190	−37.4%	14+	before history	0.75%
EW	Edwards Lifesciences Corp Healthcare	Added	189,597	+18,451	$17,884,685	+26.3%	14+	before history	0.73%
HUM	Humana Inc Healthcare	Held	36,794	0	$16,451,701	−7.9%	14+	before history	0.67%
		Added	173,248	+38,124	$15,782,893	+77.1%	14+	before history	0.65%
BAX	Baxter International Inc Healthcare	Added	324,370	+257,058	$14,778,297	+441.3%	2	$43.31	0.60%
EXEL	Exelixis, Inc. Healthcare	Held	726,639	0	$13,886,071	−1.5%	2	$17.42	0.57%
NVS	Novartis AG Healthcare	Held	136,225	0	$13,746,464	+9.7%	14+	before history	0.56%
		Added	58,577	+5,125	$12,702,422	+30.8%	13	unpriced	0.52%
PODD	Insulet Corp Healthcare	NEW	43,847	NEW	$12,642,843	NEW	1	$303.74	0.52%
GH	Guardant Health, Inc. Healthcare	Reduced	346,084	-126,100	$12,389,807	+11.9%	14+	before history	0.51%
ASND	Ascendis Pharma A/S Healthcare	Added	138,791	+15,000	$12,387,096	−6.7%	14+	before history	0.51%
XBI	State Street(R) SPDR(R) S&P(R) Biotech ETF	Held	147,677	0	$12,286,726	+9.2%	6	unpriced	0.50%
THC	Tenet Healthcare Corp Healthcare	NEW	149,070	NEW	$12,131,316	NEW	1	$71.19	0.50%

Showing the top 50 of 157 positions. Create a free account to see every position, past quarters, search, filters and CSV export.

Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.