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PYXS · Pyxis Oncology, Inc.

Track PYXS — free
$3.37 +0.38 (+12.71%) At close · Aug 19
Market Cap
$256.06M
Shares
83.41M

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$3.37 Open$3.07 Day$3.06–3.50 52W close$1.06–5.34 Avg vol 30d1.4M Short int4.2M · 5.0% float · 4.2d Short vol45% Last earningsMay 20, 2026 DataOct 2021–Aug 2026 Filing10-Q · Aug 13

Up next

Next earnings call
Jun 15, 2028 Est · unconfirmed · in 95 wks
FQ3-26 quarter ends
~Sep 30, 2026 Est
filed Aug 13, 2026

Equibles Rating

blended score · not investment advice
Overall
Neutral
SellHoldBuy
Technical Neutral Momentum Very Strong Sentiment Neutral Fundamentals Weak Quant / Vol Very High
Market backdrop VIX 14.9 · calm Equity put/call 0.52
Technical
price trend
Neutral
50 / 200-day cross No cross
Price vs 200-day avg +45%
above
Price vs 50-day avg +29%
above
RSI (14) 58
neutral
MACD trend Negative
52-week position 54%
mid-range
Volume (OBV) Bearish div.
distributing
Momentum
relative strength
Very Strong
1-month return +33%
trailing
6-month return +122%
trailing
YTD return +193%
this year
Relative strength +110%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $3 › 200d $2 — 50d above 200d
Institutional flow Accumulating
+1% holders QoQ · +11 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
5.00% of float · ▲ +28.2% MoM · 4.2 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
79 holders — mid 3-yr range
Squeeze score 77
high risk · 0–100
Fundamentals
Weak
Revenue growth −14%
Y/Y
EPS growth +3%
Y/Y
Free cash flow $-63.5M
Balance sheet $15.4M
net cash
Quant / Vol
risk profile
Very High
Volatility 130%
annualized · 1-yr
Max drawdown −80%
past year
ATR 12.1%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Neutral
2 · 3 · 2
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+45% Bullish
Price vs 50-day avg
+29% Bullish
RSI (14)
58 Neutral
MACD trend
Negative Bearish
52-week position
54% Neutral
Volume (OBV)
Bearish div. Bearish
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $3 › 200d $2 — 50d above 200d
Institutional flow Accumulating
+1% holders QoQ · +11 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
5.00% of float · ▲ +28.2% MoM · 4.2 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
79 holders — mid 3-yr range
Price context
position in its 52-week range
Range low $1 Now $3 · 54% Range high $5
vs 200-day avg +45% vs 50-day avg +29%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

the company's own KPIs, from written earnings releases and filings
Metric Latest Period YoY
confirmed objective response rate 46% December 2025
disease control rate 92% December 2025
target enrollment 40 1Q26

Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
PYXS
Pyxis Oncology, Inc.
this stock
$256.06M +193.0% -14.2% 5.0%
ONC
BeOne Medicines Ltd.
$535.83B +24.0% +22179.2% 823.9 0.1%
VRTX
Vertex Pharmaceuticals Inc / Ma
$133.88B +21.8% +46.2% 30.8 1.6%
REGN
Regeneron Pharmaceuticals, Inc.
$84.27B +8.9% +20.8% 20.3 3.3%
ARGX
Argenx SE
$61.75B +22.8% 2.1%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
79
% held
41.6%
Net QoQ
+7.0M sh
Top holder
GordonMD Global Investmen…
Held Float
View
Held by Funds
Fund positions
20
View
Short & Settlement
Short Interest Rising
Shares short
4.2M
Days to cover
4.2d
Change
+918.5K sh
View
Short Volume
Short vol %
45%
As of
Aug 19, 2026
Short Total
View
Fails to Deliver
FTD shares
4.0K
Value
$11.6K
As of
Jul 31, 2026
View
Off-Exchange
Off-exchange %
40.1%
Week of
Jul 13, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$13.9M
Net income (FY)
$-79.6M
EPS diluted
$-1.28
View
Buybacks
Authorized
shares 2.7M
View
Filings
SEC Filings
Latest
8-K
Filed
Aug 13, 2026
This year
12
View
Proposed Sales
Value
$107.0K
Shares
35.0K
Filed
Jun 30, 2026
View
Exempt Offerings
Offering
$172.5M
Filed
Mar 22, 2021
View
Earnings & Events
Earnings Calls
Last call
Jun 4, 2026
View

Performance

5D 20D 120D MTD YTD
PYXS +6.0% +33.2% +121.7% +27.2% +193.0%
SPY -0.4% +2.9% +11.6% +3.0% +12.8%
vs SPY +6.4% +30.3% +110.1% +24.2% +180.3%

Capital returns

Buyback program · as of Sep 30, 2022
Authorized
shares 2.74M
Spent (derived)
Remaining

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 1782223 CUSIP 747324101 13F (30d) 76 filings 76 filers Visit website Investor relations