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AMRX · Amneal Pharmaceuticals, Inc.

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$18.15 +0.88 (+5.10%) At close · Aug 14
Market Cap
$5.80B
Shares
319.35M
All earnings calls

Earnings call · FY2025 Q4

Amneal Pharmaceuticals, Inc. Q4 FY2025 Earnings Call

Amneal Pharmaceuticals, Inc. Q4 FY2025 Earnings Call

Concluded Feb 27, 2026 Audio replay
Feb 27, 2026 47:10 32 turns
Period
FY2025 Q4
Runtime
47:10
Sources
4 artifacts

Executive readout · one minute

What matters this quarter

Amneal delivered full-year 2025 net revenue of $3.02 billion with adjusted EPS of $0.83, meeting or exceeding all guidance metrics, and issued 2026 guidance of $3.05–$3.15 billion in net revenue and $0.93–$1.03 in adjusted diluted EPS.

Specialty / Crexone (Krexone) Parkinson's launch 42 Affordable Medicines / Complex Generics 34 Biosimilars 25 Specialty / Breqia (DHE) auto-injector launch 19 R&D pipeline 17 GLP-1 collaboration with Pfizer 12

Management tone

Confident

Net tone +82 · low hedging

Grounding quotes
  • “2025 was a defining year of excellent execution and portfolio expansion at Amneal Pharmaceuticals, Inc.”
  • “In 2025, revenue grew 8%, adjusted EBITDA increased 10%, and adjusted EPS rose 43%.”
  • “We entered 2026 with a strong foundation and exciting strategic growth opportunities”
  • “We are building a diversified biopharmaceutical company that expands access and provides new therapies for patients and delivers consistent growth for investors.”

Forward guidance

2 guided metrics

Management's latest ranges and targets are included below.

Research coverage

4 live sources

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Revenue · derived Q4 $814.32M +11.5% YoY
Gross margin · derived Q4 36.5% +0.5 pp YoY
Net income · derived Q4 $35.08M

Research materials

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Key takeaways

What improved, and what deserves a closer read.

Constructive signals

  • Full-year 2025 revenue grew 8%, adjusted EBITDA rose 10%, and adjusted EPS increased 43%, marking the sixth consecutive year of growth.
  • Specialty Q4 net revenue increased 38%, driven by Crexont and Unithroid, with Crexont reaching 23,000 patients and over 3% market share one year post-launch.
  • Affordable Medicines had a heavy cadence of complex approvals and launches in Q4, including the first two inhalation products (beclomethasone dipropionate and albuterol sulfate), first long-acting injectable (risperidone extended release), ophthalmology products, the first generic for iohexol, and multiple injectable launches.
  • Approval of the fourth and fifth biosimilars in December, with biosimilar Xolair in review and a stated goal of six biosimilars in the U.S. market by 2027.
  • Launched Breqia auto-injector in Q4 for severe migraine and cluster headache, with management stating response has been beyond expectations about 90 days into launch.
  • GLP-1 collaboration with Pfizer is progressing, with two new GLP-1 manufacturing facilities on target for buildout.

Risks & pressure points

  • Q4 Affordable Medicines net revenue decreased 1% versus the prior-year quarter due to timing of revenue for key products and new launches.
  • Q4 GAAP net income was $35 million (diluted EPS of $0.11) versus a net loss of $31 million in Q4 2024, while adjusted EBITDA growth of 13% was partially offset by commercial investments, indicating margin pressure from spend.
  • Crexont gross-to-net runs 40%–45%, and iohexol is expected to ramp slowly given a complicated supply chain and GE holding huge market share, with management indicating meaningful revenue contribution from 2027 onward rather than 2026.
  • Management noted that on Crexont they worked to reduce the number of patients who could not fill prescriptions due to pricing, implying prior access limitations.

Key moments

Jump directly to management's words in the synchronized transcript.

“2025 was an exceptional year for approvals and launches, particularly in complex generics and injectables. These launches are not one-time events; they are multi-year value drivers. As a result, we expect meaningful acceleration in our Affordable Medicines segment revenue growth in 2026 and 2027.” Chirag Patel, CEO
“We have 59 ANDAs pending, products with 64% classified as complex, and 52 more products in development with 94% complex. We look to file 10 to 15 key complex programs in 2026, including several more injectables and inhalation programs. This complex portfolio evolution positions us very well for sustainable growth.” Chintu Patel, CEO

Forward guidance

From the 8-K filed Jan 13, 2026.

Metric Guided
Net revenue table Initiated
2025 full-year
$3B – $3.1B
Adjusted EBITDA table Initiated
2025 full-year
$675M – $685M
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