HCWB · HCW Biologics Inc.
Substantial doubt about the company's ability to continue as a going concern.
“The Company believes that substantial doubt exists regarding its ability to continue as a going concern for at least 12 months from the date of issuance of the Company's condensed financial statements and that the substantial doubt that existed in its going concern analysis was not alleviated.”View the 10-Q filed May 14, 2026
Trades by corporate insiders — officers, directors and holders of more than 10% of the shares — disclosed to the SEC on Forms 3, 4 and 5. Form 4 must be filed within two business days of the trade.
Insider Sentiment Score Cluster buy
Peer-relative 0–100 rank of how aggressively insiders accumulated over the trailing 90 days. See the full ranking.
| Date | Insider | Role | Type | Security | Shares |
|---|---|---|---|---|---|
| 2026-05-22 | Byam Rebecca |
Chief Financial Officer |
Buy↑
|
Common Stock
|
14,235 |
| 2026-05-22 | GARRETT SCOTT T |
Director |
Buy↑
Filing footnotes — Common Stock (Indirect)
The reporting person purchased these shares directly from the issuer in a private placement, which purchase is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock
(I)
|
177,936 |
| 2026-05-22 | Wong Hing C |
Director, Chief Executive Officer, 10% Owner |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Direct)
The reporting person purchased these shares directly from the issuer in a private placement, which purchase is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock Purchase Warrant
|
113,879 |
| 2026-05-22 | GARRETT SCOTT T |
Director |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Indirect)
The reporting person purchased these shares directly from the issuer in a private placement, which purchase is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock Purchase Warrant
(I)
|
177,936 |
| 2026-05-22 | Wong Hing C |
Director, Chief Executive Officer, 10% Owner |
Buy↑
Filing footnotes — Common Stock (Direct)
The reporting person purchased these shares directly from the issuer in a private placement, which purchase is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock
|
113,879 |
| 2026-05-22 | Byam Rebecca |
Chief Financial Officer |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Direct)
The reporting person purchased these shares directly from the issuer in a private placement, which purchase is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock Purchase Warrant
|
14,235 |
| 2025-05-16 | GARRETT SCOTT T |
Director |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares were issued pursuant to a conversion of Unsecured Convertible Promissory Notes which were issued to six holders through a Company financing of an aggregate principal of $270,000 in one-year Notes. The Notes contained a mandatory conversion provision, which resulted in the Notes converting into shares of common stock at a mandatory conversion price of $7.45 per share as set by the registered offering. The Notes converted after the closing of the Company's registered offering on May 15, 2025. The conversion transaction also included an allocated portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
13,423 |
| 2025-05-16 | Winer Gary M |
Director |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares were issued pursuant to a conversion of Unsecured Convertible Promissory Notes which were issued to six holders through a Company financing of an aggregate principal of $270,000 in one-year Notes. The Notes contained a mandatory conversion provision, which resulted in the Notes converting into shares of common stock at a mandatory conversion price of $7.45 per share as set by the registered offering. The Notes converted after the closing of the Company's registered offering on May 15, 2025. The conversion transaction also included an allocated portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
1,342 |
| 2025-05-16 | Wong Hing C |
Director, Chief Executive Officer, 10% Owner |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares were issued pursuant to a conversion of Unsecured Convertible Promissory Notes which were issued to six holders through a Company financing of an aggregate principal of $270,000 in one-year Notes. The Notes contained a mandatory conversion provision, which resulted in the Notes converting into shares of common stock at a mandatory conversion price of $7.45 per share as set by the registered offering. The Notes converted after the closing of the Company's registered offering on May 15, 2025. The conversion transaction also included an allocated portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
8,054 |
| 2025-05-08 | GARRETT SCOTT T |
Director |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
5,385 |
| 2025-05-08 | Flowers Lee |
SVP of Business Development |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
962 |
| 2025-05-08 | Winer Gary M |
Director |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
2,308 |
| 2025-05-08 | Greene Rick S. |
Director |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
962 |
| 2025-05-08 | Wong Hing C |
Director, Chief Executive Officer, 10% Owner |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
92,500 |
| 2025-05-08 | Byam Rebecca |
Chief Financial Officer |
Buy↑
Filing footnotes — Common Stock (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock
|
8,462 |
| 2025-05-07 | GARRETT SCOTT T |
Director |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock Purchase Warrant
|
2,692 |
| 2025-05-07 | Wong Hing C |
Director, Chief Executive Officer, 10% Owner |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock Purchase Warrant
|
46,250 |
| 2025-05-07 | Flowers Lee |
SVP of Business Development |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock Purchase Warrant
|
481 |
| 2025-05-07 | Byam Rebecca |
Chief Financial Officer |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock Purchase Warrant
|
4,231 |
| 2025-05-07 | Winer Gary M |
Director |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock Purchase Warrant
|
1,154 |
| 2025-05-07 | Greene Rick S. |
Director |
Buy↑
Filing footnotes — Common Stock Purchase Warrant (Direct)
These shares are being issued as a portion of and pursuant to the Company entering into a definitive conversion agreement on May 1, 2025, with a conversion date of May 7, 2025, along with 13 other holders of $6.6 million of the outstanding principal of the Secured Notes to convert the Secured Notes for an aggregate of 253,083 shares of the Company's Common Stock at a conversion price of $26.00 per share (on a post-reverse split basis), issuance of an aggregate of 126,540 warrants each exercisable for one share of Common Stock at an exercise price of $26.00 per share (on a post-reverse split basis), and a portion of the 2,174,311 shares of Wugen Inc. common stock held by the Company. |
Common Stock Purchase Warrant
|
481 |
| 2024-06-14 | Giles Lisa M. |
Director |
Award↑
Filing footnotes — Stock Option (Right to Buy) (Direct)
(1) 100% of the total number of shares subject to the Option shall vest and become exercisable on the earlier of (a) June 13, 2025 or (b) the next annual meeting of stockholders, subject to the Reporting Person continuing to provide services through the vesting date. |
Stock Option (Right to Buy)
|
12,500 |
| 2024-06-14 | Greene Rick S. |
Director |
Award↑
Filing footnotes — Stock Option (Right to Buy) (Direct)
(1) 100% of the total number of shares subject to the Option shall vest and become exercisable on the earlier of (a) June 13, 2025 or (b) the next annual meeting of stockholders, subject to the Reporting Person continuing to provide services through the vesting date. |
Stock Option (Right to Buy)
|
12,500 |
| 2024-06-14 | GARRETT SCOTT T |
Director |
Award↑
Filing footnotes — Stock Option (Right to Buy) (Direct)
(1) 100% of the total number of shares subject to the Option shall vest and become exercisable on the earlier of (a) June 13, 2025 or (b) the next annual meeting of stockholders, subject to the Reporting Person continuing to provide services through the vesting date. |
Stock Option (Right to Buy)
|
12,500 |
| 2024-06-14 | Winer Gary M |
Director |
Award↑
Filing footnotes — Stock Option (Right to Buy) (Direct)
(1) 100% of the total number of shares subject to the Option shall vest and become exercisable on the earlier of (a) June 13, 2025 or (b) the next annual meeting of stockholders, subject to the Reporting Person continuing to provide services through the vesting date. |
Stock Option (Right to Buy)
|
12,500 |
| 2024-02-20 | Flowers Lee |
SVP of Business Development |
Award↑
Filing footnotes — Common Stock (Direct)
The reporting person purchased these shares directly from the issuer in a private placement, which transaction is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock
|
71,429 |
| 2024-02-20 | GARRETT SCOTT T |
Director |
Award↑
Filing footnotes — Common Stock (Indirect)
The reporting person purchased these shares directly from the issuer in a private placement, which transaction is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock
(I)
|
142,858 |
| 2024-02-20 | Wong Hing C |
Director, Chief Executive Officer, 10% Owner |
Award↑
Filing footnotes — Common Stock (Direct)
The reporting person purchased these shares directly from the issuer in a private placement, which transaction is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock
|
739,288 |
| 2024-02-20 | Byam Rebecca |
Chief Financial Officer |
Award↑
Filing footnotes — Common Stock (Direct)
The reporting person purchased these shares directly from the issuer in a private placement, which transaction is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock
|
760,714 |
| 2024-02-20 | Giles Lisa M. |
Director |
Award↑
Filing footnotes — Common Stock (Direct)
The reporting person purchased these shares directly from the issuer in a private placement, which transaction is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock
|
35,715 |
| 2024-02-20 | Greene Rick S. |
Director |
Award↑
Filing footnotes — Common Stock (Direct)
The reporting person purchased these shares directly from the issuer in a private placement, which transaction is exempt from Section 16(b) in accordance with Rule 16b-3(d) promulgated under the Securities Exchange Act of 1934, as amended. |
Common Stock
|
35,714 |
| 2023-12-11 | Rhode Peter |
See Remarks |
Convert↓
Filing footnotes — Stock Option (Right to Buy) (Direct)
These option shares were part of a stock option grant covering 85,713 shares of common stock. 20% of the total shares subject to the stock option grant vested on May 30, 2020; 20% of the total shares subject to the stock option grant vested on May 30, 2021; 25% of the total shares subject to the stock option grant vested on May 30, 2022; and 35% of the total shares subject to the stock option grant vested on May 30, 2023, subject to the reporting person's continuous service through the applicable vesting date. |
Stock Option (Right to Buy)
|
14,000 |
| 2023-12-11 | Rhode Peter |
See Remarks |
Convert↑
|
Common Stock
|
14,000 |
| 2023-12-08 | Flowers Lee |
SVP of Business Development |
Convert↑
|
Common Stock
|
7,501 |
| 2023-12-08 | Flowers Lee |
SVP of Business Development |
Convert↓
Filing footnotes — Stock Option (Right to Buy) (Direct)
20% of the total shares subject to the stock option grant vested on September 16, 2020; 20% of the total shares subject to the stock option grant vested on September 16, 2021; 25% of the total shares subject to the stock option grant vested on September 16, 2022; and 35% of the total shares subject to the stock option grant vested on September 16, 2023. |
Stock Option (Right to Buy)
|
7,501 |
| 2023-11-17 | Rhode Peter |
See Remarks |
Convert↑
|
Common Stock
|
15,000 |
| 2023-11-17 | Rhode Peter |
See Remarks |
Convert↓
Filing footnotes — Stock Option Grant (Right to Buy) (Direct)
These option shares were part of a stock option grant covering 85,713 shares of common stock. 20% of the total shares subject to the stock option grant vested on May 30, 2020; 20% of the total shares subject to the stock option grant vested on May 30, 2021; 25% of the total shares subject to the stock option grant vested on May 30, 2022; and 35% of the total shares subject to the stock option grant vested on May 30, 2023, subject to the reporting person's continuous service through the applicable vesting date. |
Stock Option Grant (Right to Buy)
|
15,000 |
| 2023-10-19 | Byam Rebecca |
Chief Financial Officer |
Convert↑
|
Common Stock
|
47,249 |
| 2023-10-19 | Byam Rebecca |
Chief Financial Officer |
Convert↓
Filing footnotes — Stock Option Grant (Right to Buy) (Direct)
These option shares were part of a stock option grant covering 135,000 shares of common stock. 20% of the total shares subject to the stock option grant vested on October 10, 2020; 20% of the total shares subject to the stock option grant vested on October 10, 2021; 25% of the total shares subject to the stock option grant vested on October 10, 2022; and 35% of the total shares subject to the stock option grant vested on October 10, 2023, subject to her continuous service through the applicable vesting date. The option is subject to additional vesting acceleration pursuant to her Employment Agreement. |
Stock Option Grant (Right to Buy)
|
47,249 |
| 2023-09-14 | Wong Hing C |
Director, Chief Executive Officer, 10% Owner |
Buy↑
Filing footnotes — Common Stock (Direct)
The range of prices for the shares of Common Stock is from $2.0536 to $2.1109. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price. |
Common Stock
|
1,800 |
| 2023-09-14 | Winer Gary M |
Director |
Buy↑
|
Common Stock
|
879 |
| 2023-09-14 | Winer Gary M |
Director |
Buy↑
|
Common Stock
|
162 |
| 2023-09-13 | Winer Gary M |
Director |
Buy↑
|
Common Stock
|
46 |
| 2023-09-13 | Byam Rebecca |
Chief Financial Officer |
Buy↑
Filing footnotes — Common Stock (Direct)
The range of prices for the shares of Common Stock is from $2.07 to $2.10. The reporting person undertakes that she will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price. |
Common Stock
|
5,000 |
| 2023-09-13 | Winer Gary M |
Director |
Buy↑
|
Common Stock
|
500 |
| 2023-09-12 | Byam Rebecca |
Chief Financial Officer |
Buy↑
Filing footnotes — Common Stock (Direct)
The range of prices for the shares of Common Stock is from $2.07 to $2.10. The reporting person undertakes that she will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price. |
Common Stock
|
5,000 |
| 2023-09-12 | Winer Gary M |
Director |
Buy↑
Filing footnotes — Common Stock (Direct)
The range of prices for the shares of Common Stock is from $2.01 to $2.05. The reporting person undertakes that he will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price. |
Common Stock
|
500 |
| 2023-09-11 | Winer Gary M |
Director |
Buy↑
|
Common Stock
|
99 |
| 2023-09-11 | Byam Rebecca |
Chief Financial Officer |
Buy↑
Filing footnotes — Common Stock (Direct)
The range of prices for the shares of Common Stock is from $2.01 to $2.09. The reporting person undertakes that she will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price. |
Common Stock
|
5,000 |
| 2023-09-08 | Byam Rebecca |
Chief Financial Officer |
Buy↑
Filing footnotes — Common Stock (Direct)
The range of prices for the shares of Common Stock is from $1.95 to $2.05. The reporting person undertakes that she will provide, upon request by the staff of the U.S. Securities and Exchange Commission, full information regarding the number of securities purchased at each separate price. |
Common Stock
|
5,000 |