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PYXS · Pyxis Oncology, Inc.

Track PYXS — free
$3.89 +0.33 (+9.12%) At close · Sep 4
Market Cap
$324.46M
Shares
83.41M

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$3.89 Open$3.53 Day$3.52–4.05 52W close$1.06–5.34 Avg vol 30d1.3M Short int4.4M · 5.3% float · 2.0d Short vol43% Last earningsMay 20, 2026 DataOct 2021–Sep 2026 Filing10-Q · Aug 13

Up next

Next earnings call
Jun 15, 2028 Est · unconfirmed · in 92 wks
filed Aug 13, 2026

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$2.82M
Trailing 12 months
Net income (TTM)
−$88.73M
Trailing 12 months
Revenue growth YoY
-14.2%
Year over year
Operating margin
-609.2%
Trailing 12 months
P / E (TTM)
Trailing earnings
FCF yield
TTM · current market cap
Return on invested capital
Trailing 12 months
Net cash
$33.00M
Latest balance sheet
Dividend yield
Trailing 12 months
Shares change YoY
+3.3%
Year over year · more shares
Price change (1Y)
+141.6%
Trailing year
Short interest
5.3%
Latest settlement · 2.0 days to cover
View all 114 metrics

Equibles Rating

blended score · not investment advice
Overall
Neutral
SellHoldBuy
Technical Buy Momentum Very Strong Sentiment Neutral Fundamentals Poor Quant / Vol Very High
Market backdrop VIX 14.5 · calm Equity put/call 0.58
Technical
price trend
Buy
50 / 200-day cross No cross
Price vs 200-day avg +71%
above
Price vs 50-day avg +31%
above
RSI (14) 64
neutral
MACD trend Positive
52-week position 66%
mid-range
Volume (OBV) Bearish div.
distributing
Momentum
relative strength
Very Strong
1-month return +4%
trailing
6-month return +133%
trailing
YTD return +238%
this year
Relative strength +118%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $3 › 200d $2 — 50d above 200d
Institutional flow Accumulating
+1% holders QoQ · +11 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
5.31% of float · ▲ +6.1% MoM · 2.0 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
79 holders — mid 3-yr range
Squeeze score 61
elevated · 0–100
Fundamentals
Poor
Revenue growth −14%
Y/Y
EPS growth +3%
Y/Y
Free cash flow $-63.5M
Quant / Vol
risk profile
Very High
Volatility 129%
annualized · 1-yr
Max drawdown −80%
past year
ATR 8.9%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Buy
1 · 3 · 3
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+71% Bullish
Price vs 50-day avg
+31% Bullish
RSI (14)
64 Neutral
MACD trend
Positive Bullish
52-week position
66% Neutral
Volume (OBV)
Bearish div. Bearish
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $3 › 200d $2 — 50d above 200d
Institutional flow Accumulating
+1% holders QoQ · +11 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
5.31% of float · ▲ +6.1% MoM · 2.0 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
79 holders — mid 3-yr range
Price context
position in its 52-week range
Range low $1 Now $4 · 66% Range high $5
vs 200-day avg +71% vs 50-day avg +31%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
PYXS
Pyxis Oncology, Inc.
this stock
$324.46M +238.3% -14.2% 5.3%
VRTX
Vertex Pharmaceuticals Inc / Ma
$138.42B +20.5% +46.2% 31.8 1.6%
REGN
Regeneron Pharmaceuticals, Inc.
$85.22B +7.2% +20.8% 20.5 2.3%
ARGX
Argenx SE
$64.25B +22.9% 1.9%
CSLLY
Csl Ltd
$60.55B 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
79
% held
41.6%
Net QoQ
+7.0M sh
Top holder
GordonMD Global Investmen…
Held Float
View
Held by Funds
Fund positions
19
View
Short & Settlement
Short Interest Rising
Shares short
4.4M
Days to cover
2.0d
Change
+253.4K sh
View
Short Volume
Short vol %
43%
As of
Sep 4, 2026
Short Total
View
Fails to Deliver
FTD shares
179
Value
$507
As of
Aug 12, 2026
View
Off-Exchange
Off-exchange %
42.8%
Week of
Jul 27, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$13.9M
Net income (FY)
$-79.6M
EPS diluted
$-1.28
View
Buybacks
Authorized
shares 2.7M
View
Filings
SEC Filings
Latest
8-K
Filed
Aug 13, 2026
This year
12
View
Proposed Sales
Value
$107.0K
Shares
35.0K
Filed
Jun 30, 2026
View
Exempt Offerings
Offering
$172.5M
Filed
Mar 22, 2021
View
Earnings & Events
Earnings Calls
Last call
Jun 4, 2026
View

Performance

5D 20D 120D MTD YTD
PYXS +20.4% +4.3% +132.9% +20.1% +238.3%
SPY +0.1% -0.4% +15.1% +0.4% +12.9%
vs SPY +20.3% +4.7% +117.8% +19.7% +225.3%

Capital returns

Buyback program · as of Sep 30, 2022
Authorized
shares 2.74M
Spent (derived)
Remaining

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 1782223 CUSIP 747324101 13F (30d) 60 filings 60 filers Visit website Investor relations