Defilade Capital Management, L.P.
Filing Date
Global Rank
#2,296
/ 8,696
▲ 579
Top Industry
Biotechnology
38.9%
3Y Alpha vs SPY
-5.7%
Period ended 2 months ago
Filed Aug 14, 2026 · 29d
3 quarters · since Dec 2025
Clone Performance
Feb 2026–Sep 2026 · vs SPYHypothetical growth of buying every stock this filer reported holding, rebalancing on each filing and indexed to the same start. Option positions cannot be bought this way and are left out.
Cloned portfolio
+5.6%
SPY
+12.1%
Annualised alpha
-12.0%
Max drawdown
−13.3%
Estimate. 13F holdings are quarter-lagged, so the clone rebalances about 45 days after each period end — when the filing becomes public — and it excludes option and short positions. Returns use comparable raw closes and exclude dividends. Returns are unavailable when a held security or benchmark crosses a captured split without a certified price basis; the requested window is not shortened to hide it. It tracks 100% of reported value on average across 3 quarters. Past performance does not predict future results.
Portfolio Concentration
39 tracked positions · as of Jun 30, 2026 · Δ vs Mar 31, 2026Top Position
6.3%
−1.2 pts
Top 5
27.6%
−3.5 pts
Top 10
46.5%
−7.1 pts
HHI
343
Diversified−82
Portfolio Trend
3 quarters · across all stocks
Sector Breakdown
As of Jun 30, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 100.0% | $746,949,621 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
9 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| PFE | Pfizer Inc | +307,614 | 1,771,743 | $42,663,571 | |
| ORIC | Oric Pharmaceuticals, Inc. | +204,762 | 1,047,690 | $11,346,482 | |
| EVMN | Evommune, Inc. | +114,556 | 793,145 | $10,540,897 | |
| INSM | INSMED Inc | +86,929 | 281,838 | $30,049,567 | |
| PTCT | Ptc Therapeutics, Inc. | +57,534 | 433,699 | $35,376,827 | |
| ASND | Ascendis Pharma A/S | +42,948 | 94,843 | $25,296,524 | |
| COGT | Cogent Biosciences, Inc. | +40,851 | 393,441 | $15,226,166 | |
| LLY | ELI LILLY & Co | +18,390 | 39,086 | $46,880,924 | |
| OCUL | Ocular Therapeutix, Inc | +2,641 | 1,490,286 | $14,634,608 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
10 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| DNLI | Denali Therapeutics Inc. | −968,103 | 391,866 | $10,078,793 | |
| OLMA | Olema Pharmaceuticals, Inc. | −579,778 | 924,758 | $11,568,722 | |
| PACS | PACS Group, Inc. | −388,505 | 215,675 | $9,196,382 | |
| ZBH | Zimmer Biomet Holdings, Inc. | −261,735 | 317,426 | $27,327,204 | |
| RVMD | Revolution Medicines, Inc. | −233,145 | 82,827 | $15,511,840 | |
| GMED | Globus Medical Inc | −214,713 | 139,637 | $11,032,719 | |
| ICUI | Icu Medical Inc/De | −148,591 | 105,700 | $15,495,620 | |
| LNTH | Lantheus Holdings, Inc. | −116,739 | 132,662 | $14,717,522 | |
| ELAN | Elanco Animal Health Inc | −67,041 | 864,080 | $21,265,008 | |
| ELDN | Eledon Pharmaceuticals, Inc. | −38,789 | 3,525,338 | $13,889,831 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
19 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| VEEV | Veeva Systems Inc | 236,709 | $42,008,746 | |
| BMRN | Biomarin Pharmaceutical Inc | 682,005 | $39,024,326 | |
| BAX | Baxter International Inc | 1,459,380 | $31,113,981 | |
| PODD | Insulet Corp | 176,932 | $26,937,897 | |
| TMO | Thermo Fisher Scientific Inc. | 51,934 | $26,037,630 | |
| ABT | Abbott Laboratories | 285,778 | $25,931,495 | |
| SOLV | Solventum Corp | 316,454 | $24,414,426 | |
| MDT | Medtronic plc | 303,301 | $23,727,237 | |
| AGIO | Agios Pharmaceuticals, Inc. | 546,848 | $20,293,529 | |
| NVST | Envista Holdings Corp | 726,108 | $19,132,945 | |
| TYRA | Tyra Biosciences, Inc. | 376,870 | $12,037,227 | |
| LRMR | Larimar Therapeutics, Inc. | 3,670,135 | $11,193,911 | |
| ENOV | Enovis CORP | 531,945 | $11,011,261 | |
| TFX | Teleflex Inc | 80,118 | $10,155,757 | |
| GKOS | GLAUKOS Corp | 66,519 | $9,296,695 | |
| STAA | Staar Surgical Co | 322,126 | $9,241,794 | |
| CRNX | Crinetics Pharmaceuticals, Inc. | 239,440 | $8,959,844 | |
| LIVN | LivaNova PLC | 107,373 | $8,829,281 | |
| BDTX | Black Diamond Therapeutics, Inc. | 1,674,999 | $3,098,748 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
11 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| HSIC | Henry Schein Inc | 624,037 | $45,991,526 | |
| BDX | Becton Dickinson & Co | 279,210 | $43,900,188 | |
| DXCM | Dexcom Inc | 538,762 | $33,834,253 | |
| ISRG | Intuitive Surgical Inc | 67,681 | $31,200,264 | |
| NBIX | Neurocrine Biosciences Inc | 209,932 | $27,656,441 | |
| ITGR | Integer Holdings Corp | 213,027 | $18,746,376 | |
| BIIB | Biogen Inc. | 96,289 | $17,652,662 | |
| TNDM | Tandem Diabetes Care Inc | 761,905 | $14,605,718 | |
| ALGN | Align Technology Inc | 67,332 | $11,542,724 | |
| BHVN | Biohaven Ltd. | 315,944 | $2,672,886 | |
| — | 129,950 | $0 | ||
| No positions match the current search. | ||||
39 tracked positions ·
$746,949,621 total
· filing declares
39 positions · $746,947,371
· as of Jun 30, 2026
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| LLY |
ELI LILLY & Co
Healthcare
|
Added | 39,086 | $46,880,924 | 6.28% | |
| PFE |
Pfizer Inc
Healthcare
|
Added | 1,771,743 | $42,663,571 | 5.71% | |
| VEEV |
Veeva Systems Inc
Healthcare
|
NEW | 236,709 | $42,008,746 | 5.62% | |
| BMRN |
Biomarin Pharmaceutical Inc
Healthcare
|
NEW | 682,005 | $39,024,326 | 5.22% | |
| PTCT |
Ptc Therapeutics, Inc.
Healthcare
|
Added | 433,699 | $35,376,827 | 4.74% | |
| BAX |
Baxter International Inc
Healthcare
|
NEW | 1,459,380 | $31,113,981 | 4.17% | |
| INSM |
INSMED Inc
Healthcare
|
Added | 281,838 | $30,049,567 | 4.02% | |
| ZBH |
Zimmer Biomet Holdings, Inc.
Healthcare
|
Reduced | 317,426 | $27,327,204 | 3.66% | |
| PODD |
Insulet Corp
Healthcare
|
NEW | 176,932 | $26,937,897 | 3.61% | |
| TMO |
Thermo Fisher Scientific Inc.
Healthcare
|
NEW | 51,934 | $26,037,630 | 3.49% | |
| ABT |
Abbott Laboratories
Healthcare
|
NEW | 285,778 | $25,931,495 | 3.47% | |
| ASND |
Ascendis Pharma A/S
Healthcare
|
Added | 94,843 | $25,296,524 | 3.39% | |
| SOLV |
Solventum Corp
Healthcare
|
NEW | 316,454 | $24,414,426 | 3.27% | |
| MDT |
Medtronic plc
Healthcare
|
NEW | 303,301 | $23,727,237 | 3.18% | |
| ELAN |
Elanco Animal Health Inc
Healthcare
|
Reduced | 864,080 | $21,265,008 | 2.85% | |
| AGIO |
Agios Pharmaceuticals, Inc.
Healthcare
|
NEW | 546,848 | $20,293,529 | 2.72% | |
| NVST |
Envista Holdings Corp
Healthcare
|
NEW | 726,108 | $19,132,945 | 2.56% | |
| RVMD |
Revolution Medicines, Inc.
Healthcare
|
Reduced | 82,827 | $15,511,840 | 2.08% | |
| ICUI |
Icu Medical Inc/De
Healthcare
|
Reduced | 105,700 | $15,495,620 | 2.07% | |
| COGT |
Cogent Biosciences, Inc.
Healthcare
|
Added | 393,441 | $15,226,166 | 2.04% | |
| LNTH |
Lantheus Holdings, Inc.
Healthcare
|
Reduced | 132,662 | $14,717,522 | 1.97% | |
| OCUL |
Ocular Therapeutix, Inc
Healthcare
|
Added | 1,490,286 | $14,634,608 | 1.96% | |
| ELDN |
Eledon Pharmaceuticals, Inc.
Healthcare
|
Reduced | 3,525,338 | $13,889,831 | 1.86% | |
| TYRA |
Tyra Biosciences, Inc.
Healthcare
|
NEW | 376,870 | $12,037,227 | 1.61% | |
| OLMA |
Olema Pharmaceuticals, Inc.
Healthcare
|
Reduced | 924,758 | $11,568,722 | 1.55% | |
| ORIC |
Oric Pharmaceuticals, Inc.
Healthcare
|
Added | 1,047,690 | $11,346,482 | 1.52% | |
| LRMR |
Larimar Therapeutics, Inc.
Healthcare
|
NEW | 3,670,135 | $11,193,911 | 1.50% | |
| GMED |
Globus Medical Inc
Healthcare
|
Reduced | 139,637 | $11,032,719 | 1.48% | |
| ENOV |
Enovis CORP
Healthcare
|
NEW | 531,945 | $11,011,261 | 1.47% | |
| EVMN |
Evommune, Inc.
Healthcare
|
Added | 793,145 | $10,540,897 | 1.41% | |
| TFX |
Teleflex Inc
Healthcare
|
NEW | 80,118 | $10,155,757 | 1.36% | |
| DNLI |
Denali Therapeutics Inc.
Healthcare
|
Reduced | 391,866 | $10,078,793 | 1.35% | |
| GKOS |
GLAUKOS Corp
Healthcare
|
NEW | 66,519 | $9,296,695 | 1.24% | |
| STAA |
Staar Surgical Co
Healthcare
|
NEW | 322,126 | $9,241,794 | 1.24% | |
| PACS |
PACS Group, Inc.
Healthcare
|
Reduced | 215,675 | $9,196,382 | 1.23% | |
| CRNX |
Crinetics Pharmaceuticals, Inc.
Healthcare
|
NEW | 239,440 | $8,959,844 | 1.20% | |
| LIVN |
LivaNova PLC
Healthcare
|
NEW | 107,373 | $8,829,281 | 1.18% | |
| BDTX |
Black Diamond Therapeutics, Inc.
Healthcare
|
NEW | 1,674,999 | $3,098,748 | 0.41% | |
| MREO |
Mereo BioPharma Group plc
Healthcare
|
Held | 7,558,756 | $2,403,684 | 0.32% |
Covers the securities this platform tracks: U.S.-listed common stock and the put/call positions reported on it. A 13F can also report security types outside that coverage — preferred shares, bonds, warrants, untracked share classes — so the filing's own declared total can exceed the figures above. The source filing is linked at the top of this table.