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SPRB · Spruce Biosciences, Inc.

Track SPRB — free
$52.96 +0.12 (+0.22%) At close · Aug 19
Market Cap
$152.61M
Shares
2.87M

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$52.96 Open$54.18 Day$52.02–54.93 52W close$7.00–182.60 Avg vol 30d56K Short int429K · 14.9% float · 7.6d Short vol63% Last earningsNov 12, 2024 DataAug 2025–Aug 2026 Filing10-Q · Aug 12

Raw chart and full-history price indicators begin at the captured split on Aug 7, 2025; bars on opposite sides are not compared.

Up next

FQ3-26 quarter ends
~Sep 30, 2026 Est
filed Aug 12, 2026

Equibles Rating

blended score · not investment advice
Overall
Sell
SellHoldBuy
Technical Buy Momentum Weak Sentiment Neutral Fundamentals Fair Quant / Vol Very High
Market backdrop VIX 14.9 · calm Equity put/call 0.52
Technical
price trend
Buy
50 / 200-day cross No cross
Price vs 200-day avg −21%
below
Price vs 50-day avg +9%
above
RSI (14) 68
neutral
MACD trend Positive
52-week position 26%
mid-range
Momentum
relative strength
Weak
1-month return +19%
trailing
6-month return −10%
trailing
YTD return −39%
this year
Relative strength −21%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $48 › 200d $67 — 200d above 50d
Institutional flow Accumulating
+97% holders QoQ · +35 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
14.93% of float · ▲ +3.2% MoM · 7.6 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
63 holders — near 3-yr high, broad support
Squeeze score 75
high risk · 0–100
Fundamentals
Fair
Revenue growth −100%
Y/Y
EPS growth +47%
Y/Y
Free cash flow $-33.3M
Balance sheet $48.9M
net cash
Quant / Vol
risk profile
Very High
Volatility 1386%
annualized · 1-yr
Max drawdown −77%
past year
ATR 5.5%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Buy
1 · 3 · 2
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
−21% Bearish
Price vs 50-day avg
+9% Bullish
RSI (14)
68 Neutral
MACD trend
Positive Bullish
52-week position
26% Neutral
Market signals — smart money & positioning
Bullish · 2 of 6
Trend (MA cross) No cross
50d $48 › 200d $67 — 200d above 50d
Institutional flow Accumulating
+97% holders QoQ · +35 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
14.93% of float · ▲ +3.2% MoM · 7.6 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
63 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $7 Now $53 · 26% Range high $183
vs 200-day avg -21% vs 50-day avg +9%

Illustrative technical + ownership context — a signal mix, not investment advice.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
SPRB
Spruce Biosciences, Inc.
this stock
$152.61M -39.2% -100.0% 14.9%
ONC
BeOne Medicines Ltd.
$535.83B +24.0% +22179.2% 823.9 0.1%
VRTX
Vertex Pharmaceuticals Inc / Ma
$133.88B +21.8% +46.2% 30.8 1.6%
REGN
Regeneron Pharmaceuticals, Inc.
$84.27B +8.9% +20.8% 20.3 3.3%
ARGX
Argenx SE
$61.75B +22.8% 2.1%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
63
% held
69.7%
Net QoQ
+1.3M sh
Top holder
AIGH Capital Management L…
Held Float
View
Held by Funds
Fund positions
15
View
Short & Settlement
Short Interest Rising
Shares short
429.1K
Days to cover
7.6d
Change
+13.3K sh
View
Short Volume
Short vol %
63%
As of
Aug 19, 2026
Short Total
View
Fails to Deliver
FTD shares
110
Value
$4.6K
As of
Jul 30, 2026
View
Off-Exchange
Off-exchange %
31.2%
Week of
Jul 13, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$0
Net income (FY)
$-39.0M
EPS diluted
$-50.83
View
Filings
SEC Filings
Latest
8-K
Filed
Aug 12, 2026
This year
15
View
Proposed Sales
Value
$3.9M
Shares
4.8M
Filed
Mar 18, 2024
View
Exempt Offerings
Offering
$50.0M
Filed
Oct 17, 2025
View
Earnings & Events
Earnings Calls
Last call
Jun 4, 2026
View
Investor Relations
Latest news
Spruce Biosciences Reports Second…
Published
Aug 12, 2026
View

Performance

Raw-price comparisons begin at the captured split on Aug 7, 2025; windows that need an earlier baseline remain unavailable.

5D 20D 120D MTD YTD
SPRB +12.5% +18.7% -9.6% +23.7% -39.2%
SPY -0.4% +2.9% +11.6% +3.0% +12.8%
vs SPY +13.0% +15.8% -21.1% +20.7% -52.0%
Key facts CIK 1683553 CUSIP 85209E208 13F (30d) 69 filings 65 filers Visit website Investor relations