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SPRB · Spruce Biosciences, Inc.

$42.28 -2.71 (-6.02%) At close · Jul 24
Market Cap
$118.57M
Shares
2.75M

Price & Indicators

20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$44.99 Open$44.16 Day$42.51–45.06 52W$7.00–838.13 Avg vol 30d81K Short int416K · 15.1% float · 6.1d Short vol35% Last earningsNov 12, 2024 DataOct 2020–Jul 2026 Filing10-Q · May 13

Up next

FQ3-26 quarter ends
~Sep 30, 2026 Est
filed May 13, 2026

Equibles Rating

blended score · not investment advice
Overall
Strong Sell
SellHoldBuy
Technical Strong Sell Momentum Very Weak Sentiment Neutral Fundamentals Fair Quant / Vol Very High
Market backdrop VIX 18.6 · elevated Equity put/call 0.79
Technical
price trend
Strong Sell
50 / 200-day cross No cross
Price vs 200-day avg −41%
below
Price vs 50-day avg −11%
below
RSI (14) 39
neutral
MACD trend Negative
52-week position 5%
near low
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Very Weak
1-month return −13%
trailing
6-month return −44%
trailing
YTD return −48%
this year
Relative strength −50%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $50 › 200d $76 — 200d above 50d
Institutional flow Accumulating
4 of 32 funds reported for Jun 30 · net +872 sh shares · +3 new
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
15.11% of float · ▲ +15.7% MoM · 6.1 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
32 holders — 13F breadth
Squeeze score 73
high risk · 0–100
Fundamentals
Fair
Revenue growth −100%
Y/Y
EPS growth +47%
Y/Y
Free cash flow $-33.3M
Balance sheet $48.9M
net cash
Quant / Vol
risk profile
Very High
Volatility 1390%
annualized · 1-yr
Max drawdown −99%
past year
ATR 6.8%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Strong Sell
4 · 3 · 0
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
−41% Bearish
Price vs 50-day avg
−11% Bearish
RSI (14)
39 Neutral
MACD trend
Negative Bearish
52-week position
5% Bearish
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $50 › 200d $76 — 200d above 50d
Institutional flow Accumulating
4 of 32 funds reported for Jun 30 · net +872 sh shares · +3 new
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
15.11% of float · ▲ +15.7% MoM · 6.1 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
32 holders — 13F breadth
Price context
position in its 52-week range
52-wk low $7 Now $45 · 5% 52-wk high $838
vs 200-day avg -41% vs 50-day avg -11%

Illustrative technical + ownership context — a signal mix, not investment advice.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
SPRB
Spruce Biosciences, Inc.
this stock
$118.57M -48.4% -100.0% 15.1%
ONC
BeOne Medicines Ltd.
$471.01B +7.6% +22179.2% 958.5 0.1%
VRTX
Vertex Pharmaceuticals Inc / Ma
$121.16B +4.4% +46.2% 28.3 2.0%
REGN
Regeneron Pharmaceuticals, Inc.
$68.78B -15.4% +20.8% 16.0 3.3%
ARGX
Argenx SE
$57.44B +9.9% 2.5%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
34
% held
26.9%
Reported
4 of 32
Top holder
Ikarian Capital, LLC
Held Float
View
Held by Funds
Fund positions
10
View
Short & Settlement
Short Interest Rising
Shares short
415.9K
Days to cover
6.1d
Change
+56.5K sh
View
Short Volume
Short vol %
35%
As of
Jul 24, 2026
Short Total
View
Fails to Deliver
FTD shares
36.7K
Value
$2.1M
As of
Jun 30, 2026
View
Off-Exchange
Off-exchange %
45.0%
Week of
May 4, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$0
Net income (FY)
$-39.0M
EPS diluted
$-50.83
View
Filings
SEC Filings
Latest
Investor Event Transcript
Filed
Jun 30, 2026
This year
12
View
Proposed Sales
Value
$3.9M
Shares
4.8M
Filed
Mar 18, 2024
View
Exempt Offerings
Offering
$50.0M
Filed
Oct 17, 2025
View
Earnings & Events
Earnings Calls
Last call
Jun 4, 2026
View
Investor Relations
Latest news
Spruce Biosciences to Participate…
Published
Jul 8, 2026
View

Performance

5D 20D 120D MTD YTD
SPRB +1.6% -13.3% -43.7% -16.7% -48.4%
SPY -1.7% +0.7% +6.4% -1.2% +8.3%
vs SPY +3.3% -13.9% -50.0% -15.5% -56.6%
Key facts CIK 1683553 CUSIP 85209E208 13F (30d) 3 filings 3 filers Visit website Investor relations