Skip to main content
ARVN logo

ARVN · Arvinas, Inc.

Track ARVN — free
$6.82 -0.05 (-0.73%) At close · Nov 13
Market Cap
$446.61M
Shares
65.49M
Volume · Nov 13 879.4K Avg daily vol (3M) 801.59K

Price & Indicators

Drag to pan · scroll to zoom
20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$6.82 Open$6.88 Day$6.62–6.90 52W close$6.41–13.83 Avg vol 30d853K Short int5.8M · 8.8% of shares · 7.6d Short vol53% Last earningsNov 3, 2026 DataJan 2020–Nov 2026 Filing10-Q · Nov 3

Up next

Feb 23, 2027 Est · unconfirmed · in 14 wks

Latest documents

2026
Nov 3
Earnings call
Cash runway reaches second half of 2028

Arvinas ended the third quarter with $558.9 million in cash and securities and expects cash into the second half of 2028. Milestones include ARV 393 data in December and ARV 102 Phase 1B initiation in 2027.

6 source passages
At the end of the third quarter, we had $558.9 million in cash, cash equivalents, restricted cash, and marketable securities on the balance sheet, compared with $685.4 million at the end of 2025. With our healthy balance sheet and projected cash into the second half of 2028, we are well positioned to continue developing our promising oncology and neurology programs. Arvinas has already accomplished a big win, moving from a scientific promise to the first-ever FDA-approved Protac degrader. I'll begin with ARV 393, our oral BCL sixth-grader, and a great example of a program with strong scientific rationale for differentiation. During the quarter, as we continued enrolling the monotherapy and combination cohorts of our Phase I trial, we submitted our initial monotherapy dose escalation data for presentation at the ASH conference in December. Rounding out our clinical progress, I'll next provide a brief update on current plans for our LARC 2-degrader, ARV 102. Following scientific advice from CHMP, we're now prioritizing the initiation of a Phase 1B trial in the EU and the UK. Next month, we plan to submit clinical trial applications for a Phase I-B trial in patients with progressive supranuclear palsy, or PSP. Trial initiation is targeted for 2027. Open the document at this passage
Nov 3
Registration statement S-3
Shelf registration covers $400,000,000 of securities

Arvinas, Inc. registered up to $400,000,000 of securities for future sales, including up to $200,000,000 of common stock under an amended and restated equity distribution agreement with Piper Sandler & Co. and Cantor Fitzgerald & Co.

Read from the first part of this long document
3 source passages
Unless the context otherwise indicates, references in this prospectus to “Arvinas,” “we,” “our,” “us,” and “the Company” refer, collectively, to Arvinas, Inc., a Delaware corporation, and its consolidated subsidiaries. a base prospectus which covers the offering, issuance and sale by us of up to $400,000,000 of our debt securities, common stock, preferred stock, depositary shares, warrants and/or units from time to time in one or more offerings; and an equity distribution agreement prospectus that covers the offering, issuance and sale by us of up to a maximum aggregate offering price of $200,000,000 of our common stock that may be issued and sold from time to time under an amended and restated equity distribution agreement with Piper Sandler & Co. and Cantor Fitzgerald & Co. Open the document at this passage
Nov 3
Quarterly report 10-Q FY2026 Q3, ended Sep 30
VEPPANU approved and licensed to Rigel

Arvinas and Pfizer licensed VEPPANU to Rigel following its FDA approval for ESR1-mutated advanced or metastatic breast cancer; the agreement included a $70.0 million upfront payment.

Revenue $500K ▼ 98.8% Net loss $53.9M Diluted EPS -$0.82
Read from the MD&A section
3 source passages
In the second quarter of 2026, the U.S. Food and Drug Administration, or FDA, approved VEPPANU™ (vepdegestrant) for the treatment of adults with estrogen receptor-positive, or ER+/human epidermal growth factor receptor 2-negative, or HER2-, estrogen receptor 1, or ESR1, -mutated advanced or metastatic breast cancer, as detected by an FDA-authorized test, with disease progression following at least one line of endocrine-based therapy. Also in the second quarter of 2026, we and Pfizer Inc., or Pfizer, entered into a license agreement with Rigel Pharmaceuticals, Inc., or Rigel, for the exclusive global development, manufacturing, and commercialization rights for VEPPANU, or the Rigel License Agreement. Pursuant to the terms of the Rigel License Agreement, Rigel paid to us and Pfizer a one-time, upfront payment in the aggregate amount of $70.0 million. Open the document at this passage
Nov 3
Current report 8-K
ARV-6723 dosing begins; cash runway into second half of 2028

Arvinas initiated dosing in ARV-6723’s Phase 1/2 trial and reported $558.9 million in cash, cash equivalents, restricted cash and marketable securities, sufficient to fund operations into the second half of 2028.

Financial results, Regulation FD disclosure Read from the first part of this long document
3 source passages
Initiated dosing of patients in the monotherapy cohort of the Phase 1/2 clinical trial (ClinicalTrials.gov Identifier: NCT07749586) of ARV-6723, Arvinas’ first immuno-oncology degrader. As of September 30, 2026, cash, cash equivalents, restricted cash, and marketable securities were $558.9 million compared with $685.4 million as of December 31, 2025. Based on its current operating plan, Arvinas believes its cash, cash equivalents, restricted cash, and marketable securities as of September 30, 2026, is sufficient to fund planned operating expenses and capital expenditure requirements into the second half of 2028. Open the document at this passage
All documents

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$275.30M
Trailing 12 months
Net income (TTM)
−$9.50M
Trailing 12 months
Revenue growth YoY
-98.8%
Year over year
Operating margin
-12.1%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
—
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$558.00M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
-10.7%
Year over year · fewer shares
Price change (1Y)
-32.6%
Trailing year
Short interest
8.8%
Latest settlement · 7.6 days to cover
View all 125 metrics

AI Brief

Q3 FY26 earnings call · Nov 3, 2026
Q3 FY26

TL;DR. Arvinas advanced ARV-393, ARV-6723 and ARV-027, reported early ARV-393 responses and ARV-102 biomarker movement, and expects its cash to fund operations into the second half of 2028. Risks include sharply lower revenue, a wider net loss, a lower cash balance, ARV-102's U.S. clinical hold, ARV-806's dependence on a partner, and limitations in the initial ARV-393 durability and ARV-102 clinical-benefit data.

Bullish
  • + ARV-393 is scheduled to present initial Phase 1 monotherapy dose-escalation data in 4Q 2026, with additional monotherapy and glofitamab-combination data planned for mid-2027.
  • + ARV-102 Phase 1 data showed improvement in an objective measure of impaired eye movement associated with Parkinson's disease.
  • + Cash is expected to fund planned operating expenses and capital expenditures into the second half of 2028.
  • + ARV-393 produced responses across NHL subtypes, including B- and T-cell lymphomas, at early doses below those predicted to be efficacious.
  • + Arvinas recorded its first sales-based royalty under the Rigel license agreement.
Bearish
  • − Cash, cash equivalents, restricted cash, and marketable securities declined to $558.9 million from $685.4 million at year-end 2025.
  • − ARV-102 remains on clinical hold in the U.S., and investors should assume the planned Phase 1B trial will initially begin without U.S. patients.
  • − Initial ARV-393 durability information will be limited.
  • − The clinical benefit of ARV-102's oculomotor improvement remains unproven.

AI-generated from the earnings call and 8-K · may contain errors · not investment advice

Equibles Rating

blended score · not investment advice
Overall
Sell
SellHoldBuy
Technical Strong Sell Momentum Very Weak Sentiment Neutral Fundamentals Strong Quant / Vol Very High
Market backdrop VIX 19.3 · elevated Equity put/call 0.63
Technical
price trend
Strong Sell
50 / 200-day cross No cross
Price vs 200-day avg −27%
below
Price vs 50-day avg −10%
below
RSI (14) 42
neutral
MACD trend Negative
52-week position 6%
near low
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Very Weak
1-month return −2%
trailing
6-month return −24%
trailing
YTD return −43%
this year
Relative strength −24%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $8 › 200d $9 — 200d above 50d
Institutional flow Accumulating
163 of 201 funds reported for Sep 30 · net +4.3M sh shares · +20 new
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
8.78% of shares out · ▲ +2.8% MoM · 7.6 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
201 holders — mid 3-yr range
Squeeze score 61
elevated · 0–100
Fundamentals
Strong
Revenue growth −0%
Y/Y
EPS growth +59%
Y/Y
Free cash flow $-275.7M
Buyback $79.8M
remaining
Balance sheet $142.3M
net cash
Quant / Vol
risk profile
Very High
Volatility 56%
annualized · 1-yr
Max drawdown −54%
past year
ATR 6.1%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Strong Sell
4 · 3 · 0
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
−27% Bearish
Price vs 50-day avg
−10% Bearish
RSI (14)
42 Neutral
MACD trend
Negative Bearish
52-week position
6% Bearish
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $8 › 200d $9 — 200d above 50d
Institutional flow Accumulating
163 of 201 funds reported for Sep 30 · net +4.3M sh shares · +20 new
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
8.78% of shares out · ▲ +2.8% MoM · 7.6 days cover
Volume signal Normal
Volume near normal
Institution breadth Steady
201 holders — mid 3-yr range
Price context
position in its 52-week range
Range low $6 Now $7 · 6% Range high $14
vs 200-day avg -27% vs 50-day avg -10%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

the company's own KPIs, from written earnings releases and filings
Metric Latest Period YoY
ARV-027 $3.3M the three months ended June 30, 2026 filing —
ARV-102 $5.1M the three months ended June 30, 2026 filing —
ARV-393 $4.8M the three months ended June 30, 2026 filing —
ARV-806 $5.6M the three months ended June 30, 2026 filing —
Bavdegalutamide (ARV-110) -$0.4M the three months ended June 30, 2026 filing —
Cash used in operations (net of Rigel License Agreement receipts) $114.3M six months ended June 30, 2026 —
Cash, cash equivalents, and marketable securities $567.9M As of June 30, 2026 —
Non-GAAP general and administrative expenses non-GAAP 31.3M the six months ended June 30, 2026 —
Non-GAAP research and development expenses non-GAAP 105.7M the six months ended June 30, 2026 —
Non-program-specific external expense $8.5M the three months ended June 30, 2026 filing —
Other programs $1.3M the three months ended June 30, 2026 filing —
Total program-specific external expense $24.2M the three months ended June 30, 2026 filing —
Vepdegestrant (ARV-471) $4.5M the three months ended June 30, 2026 filing —

Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
ARVN
Arvinas, Inc.
this stock
$446.61M -42.5% -0.3% — 8.8%
VRTX
Vertex Pharmaceuticals Inc
$136.56B +18.8% +46.2% 34.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$98.84B +23.8% +20.8% 21.1 2.1%
MRNA
Moderna, Inc.
$90.38B +657.4% +4.3% — 8.2%
CSLLY
Csl Ltd
$66.05B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
204
% held
91.6%
Reported
163 of 201
Top holder
BlackRock, Inc.
Held Float
View
Held by Funds
Fund positions
210
View
Short & Settlement
Short Interest Rising
Shares short
5.8M
Days to cover
7.6d
Change
+159.0K sh
View
Short Volume
Short vol %
53%
As of
Nov 13, 2026
Short Total
View
Fails to Deliver
FTD shares
400
Value
$3.3K
As of
Sep 18, 2026
View
Off-Exchange
Off-exchange %
32.5%
Week of
Oct 5, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$262.6M
Net income (FY)
$-80.8M
EPS diluted
$-1.14
View
Buybacks
Authorized
$100.0M
Remaining
$79.8M
Spent Remaining
View
Filings
SEC Filings
Latest
S-3
Filed
Nov 3, 2026
This year
23

Arvinas, Inc. registered up to $400,000,000 of securities for future sales, including up to $200,000,000 of common stock under an amended and restated equity distribution agreement with Piper Sandler & Co. and Cantor Fitzgerald & Co.

View
Proposed Sales
Value
$196.2K
Shares
23.1K
Filed
Sep 22, 2026
View
Earnings & Events
Webcasts
Last webcast
Nov 3, 2026
View
Investor Relations
Latest news
Arvinas Reports Third Quarter 202…
Published
Nov 3, 2026
View

Performance

5D 20D 120D MTD YTD
ARVN +6.4% -2.2% -23.5% -13.2% -42.5%
SPY +2.6% -1.2% +0.5% -0.2% +10.6%
vs SPY +3.8% -1.0% -24.0% -13.1% -53.1%

Capital returns

Buyback program · as of Sep 30, 2025
Authorized
$100.00M
Spent (derived)
$20.20M
Remaining
$79.80M
Spent Remaining

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 1655759 CUSIP 04335A105 13F (30d) 161 filings 141 filers Visit website Investor relations