Enliven Therapeutics, Inc 8-K, filed Jun 23, 2023
Enliven Therapeutics, Inc. (ELVN)
8-K
2023-06-23
For: 2023-06-23
View Original
Added on
April 07, 2026
About this 8-K
Enliven Therapeutics, Inc filed this 8-K on June 23, 2023.
Items reported
- Item 5.07: Shareholder vote results
- Item 8.01: Other events
- Item 9.01: Financial statements and exhibits
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d)
of The Securities Exchange Act of 1934
Date of Report (Date of earliest event reported):
(Exact name of registrant as specified in its charter)
| (State or other jurisdiction of incorporation) |
(Commission File Number) |
(IRS Employer Identification No.) |
(Address of principal executive offices) |
(Zip Code) |
(720 ) 647-8519
(Registrant’s telephone number, including area code)
Not Applicable
(Former name or former address, if changed since last report)
Check the appropriate box below if the Form
8-K
filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction A.2. below): | Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |
| Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
| Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
| Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c)) |
Securities registered pursuant to Section 12(b) of the Act:
| Title of each class |
Trading Symbol |
Name of each exchange on which registered | ||
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule
12b-2
of the Securities Exchange Act of 1934 (§240.12b-2
of this chapter). Emerging growth company ☒
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Item 5.07 |
Submission of Matters to a Vote of Security Holders. |
Enliven Therapeutics, Inc. (the “
Company
”) held its Annual Meeting of stockholders (the “Annual Meeting
”) on June 23, 2023. The matters voted upon at the Annual Meeting and the voting results for each proposal are set forth below. Proposal 1: Election of two Class III Directors
| Name of Director |
For |
Withheld |
Broker Non-Votes | |||||||
| Richard Heyman, Ph.D. |
30,518,067 |
385,508 |
1,641,388 | |||||||
| Samuel Kintz, M.B.A. |
30,900,278 |
3,297 |
1,641,388 | |||||||
Each director nominee was duly elected to serve until the 2026 annual meeting of stockholders and until their successor is duly elected and qualified, subject to earlier resignation or removal.
Proposal 2: Ratification of the Appointment of Independent Registered Public Accounting Firm
| For |
Against |
Abstain | ||
32,543,338 |
1,460 |
165 |
The stockholders ratified the appointment of Deloitte & Touche LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2023.
Item 8.01 |
Other Events. |
As previously reported, on February 23, 2023, the Company effected a reverse stock split of its common stock (the “
1-for-4
Reverse Stock Split
”) in connection with its merger with Enliven Inc. (formerly, Enliven Therapeutics, Inc.) (“Former Enliven
”). In connection with such merger, the Company issued common stock to Former Enliven stockholders based on an exchange ratio of approximately 0.2951 shares of common stock for each share of Former Enliven capital stock (which exchange ratio reflects the Reverse Stock Split) (the “Exchange Ratio
”). To reflect the Reverse Stock Split and the Exchange Ratio, the audited financial statements of Former Enliven as of December 31, 2022 and 2021 and for the years then ended have been recasted and are filed herewith as Exhibit 99.1. There have been no other changes to such financial statements. The unaudited pro forma financial information of the Company as of March 31, 2023 and for the year ended December 31, 2022 and three-month period ended March 31, 2023 are filed herewith as Exhibit 99.2.
Item 9.01 |
Financial Statements and Exhibits. |
(d) Exhibits
Exhibit Number |
Exhibit Description | |
23.1 |
||
99.1 |
||
99.2 |
||
104 |
Cover Page Interactive Data File (embedded within the Inline XBRL document) | |
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
ENLIVEN THERAPEUTICS, INC. | ||
By: |
/s/ Samuel Kintz | |
Samuel Kintz | ||
President and Chief Executive Officer | ||
Date: June 23, 2023
Exhibit 23.1
CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
We consent to the incorporation by reference in Registration Statement No. 333-254978 on Form S-3 and Registration Statements Nos. 333-237117, 333-258538, 333-263554 on Form S-8 of Imara Inc. and Registration Statement No. 333-270188 on Form S-8 of Enliven Therapeutics, Inc. (formerly Imara Inc.) of our report dated March 21, 2023, (June 23, 2023, as to the effects of the exchange ratio described in Note 1) relating to the financial statements of Enliven Inc. (formerly Enliven Therapeutics, Inc.), appearing in this Current Report on Form 8-K of Enliven Therapeutics, Inc. dated June 23, 2023.
/s/ DELOITTE & TOUCHE LLP
San Jose, California
June 23, 2023
Exhibit 99.1
FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA
INDEX TO FINANCIAL STATEMENTS
ENLIVEN THERAPEUTICS, INC.
Page |
||||
Report of Independent Registered Public Accounting Firm |
F-2 |
|||
Financials Statements as of December 31, 2022 and 2021 and for the years ended December 31, 2022 and 2021 |
F-3 |
|||
Balance Sheets |
F-3 |
|||
Statements of Operations and Comprehensive Loss |
F-4 |
|||
Statements of Convertible Preferred Stock and Stockholders’ Deficit |
F-5 |
|||
Statements of Cash Flows |
F-6 |
|||
Notes to Financial Statements |
F-7 |
|||
F-1
REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
To the Stockholders and the Board of Directors of Enliven Therapeutics, Inc.
Opinion on the Financial Statements
We have audited the accompanying balance sheets of Enliven Inc. (formerly Enliven Therapeutics, Inc.) (the “Company”) as of December 31, 2022 and 2021, the related statements of operations and comprehensive loss, convertible preferred stock and stockholders’ deficit, and cash flows, for each of the two years in the period ended December 31, 2022, and the related notes (collectively referred to as the “financial statements”). In our opinion, the financial statements present fairly, in all material respects, the financial position of the Company as of December 31, 2022 and 2021, and the results of its operations and its cash flows for each of the two years in the period ended December 31, 2022, in conformity with accounting principles generally accepted in the United States of America.
Basis for Opinion
These financial statements are the responsibility of the Company’s management. Our responsibility is to express an opinion on the Company’s financial statements based on our audits. We are a public accounting firm registered with the Public Company Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Company in accordance with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the PCAOB.
We conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement, whether due to error or fraud. The Company is not required to have, nor were we engaged to perform, an audit of its internal control over financial reporting. As part of our audits, we are required to obtain an understanding of internal control over financial reporting but not for the purpose of expressing an opinion on the effectiveness of the Company’s internal control over financial reporting. Accordingly, we express no such opinion.
Our audits included performing procedures to assess the risks of material misstatement of the financial statements, whether due to error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence regarding the amounts and disclosures in the financial statements. Our audits also included evaluating the accounting principles used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements. We believe that our audits provide a reasonable basis for our opinion.
/s/ Deloitte & Touche LLP
San Jose, California
March 21, 2023 (June 23, 2023, as to the effects of the exchange ratio described in Note 1)
We have served as the Company’s auditor since 2020.
F-2
ENLIVEN THERAPEUTICS, INC.
BALANCE SHEETS
(in thousands, except share and per share amounts)
As of December 31, |
||||||||
2022 |
2021 |
|||||||
ASSETS |
||||||||
CURRENT ASSETS |
||||||||
Cash and cash equivalents |
$ |
$ |
||||||
Prepaid expenses and other current assets |
||||||||
Total current assets |
||||||||
Property and equipment, net |
||||||||
Right of use asset |
||||||||
Deferred offering costs |
||||||||
Restricted cash |
||||||||
TOTAL ASSETS |
$ |
$ |
||||||
LIABILITIES, CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ DEFICIT |
||||||||
CURRENT LIABILITIES |
||||||||
Accounts payable, net |
$ |
$ |
||||||
Accrued expenses and other current liabilities |
||||||||
Total current liabilities |
||||||||
LONG TERM LIABILITIES |
||||||||
Other non-current liabilities |
||||||||
Total liabilities |
||||||||
COMMITMENTS AND CONTINGENCIES (Note 7) |
||||||||
Convertible preferred stock, $ 2022 and December 31, 2021, liquidation preference of $ |
||||||||
STOCKHOLDERS’ EQUITY |
||||||||
Common stock $ |
||||||||
Additional paid-in capital |
||||||||
Accumulated deficit |
( |
) |
( |
) | ||||
Total stockholders’ deficit |
( |
) |
( |
) | ||||
TOTAL LIABILITIES, CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ DEFICIT |
$ |
$ |
||||||
The accompanying notes are an integral part of these financial statements
F-3
ENLIVEN THERAPEUTICS, INC.
STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
(in thousands, except share and per share amounts)
Year Ended December 31, |
||||||||
2022 |
2021 |
|||||||
| Operating expenses: |
||||||||
| Research and development |
$ |
$ |
||||||
| General and administrative |
||||||||
| |
|
|
|
|||||
| Total operating expenses |
||||||||
| |
|
|
|
|||||
| Loss from operations |
( |
) |
( |
) | ||||
| Other income (expense), net |
||||||||
| Interest income |
||||||||
| |
|
|
|
|||||
| Total other income, net |
||||||||
| |
|
|
|
|||||
| Net loss and comprehensive loss |
$ |
( |
) |
$ |
( |
) | ||
| |
|
|
|
|||||
| Net loss per share attributable to common stockholders, basic and diluted |
$ |
( |
) |
$ |
( |
) | ||
| |
|
|
|
|||||
| Weighted-average number of shares outstanding used in computing net loss per common share, basic and diluted |
||||||||
| |
|
|
|
|||||
The accompanying notes are an integral part of these financial statements
F-4
ENLIVEN THERAPEUTICS, INC.
STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ DEFICIT
(in thousands, except share amounts)
Convertible |
Additional Paid-in Capital |
Accumulated Deficit |
Total Stockholders’ Deficit |
|||||||||||||||||||||||||||
Preferred Stock |
Common Stock |
|||||||||||||||||||||||||||||
Shares |
Amount |
Shares |
Amount |
|||||||||||||||||||||||||||
| Balance - January 1, 2021 |
$ |
$ |
$ |
$ |
( |
) |
$ |
( |
) | |||||||||||||||||||||
| Exercise of common stock options |
— |
— |
— |
— |
||||||||||||||||||||||||||
| Vesting of restricted stock and stock options |
— |
— |
— |
— |
— |
|||||||||||||||||||||||||
| Stock-based compensation |
— |
— |
— |
— |
— |
|||||||||||||||||||||||||
| Net loss |
— |
— |
— |
— |
— |
( |
) |
( |
) | |||||||||||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Balance - December 31, 2021 |
( |
) |
( |
) | ||||||||||||||||||||||||||
| Exercise of common stock options |
— |
— |
— |
— |
||||||||||||||||||||||||||
| Vesting of restricted stock and stock options |
— |
— |
— |
— |
— |
|||||||||||||||||||||||||
| Stock-based compensation |
— |
— |
— |
— |
— |
|||||||||||||||||||||||||
| Net loss |
— |
— |
— |
— |
— |
( |
) |
( |
) | |||||||||||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Balance - December 31, 2022 |
$ |
$ |
$ |
$ |
( |
) |
$ |
( |
) | |||||||||||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
The accompanying notes are an integral part of these financial statements
F-5
ENLIVEN THERAPEUTICS, INC.
STATEMENTS OF CASH FLOWS
(in thousands)
Year Ended |
||||||||
December 31, |
||||||||
2022 |
2021 |
|||||||
| Cash flows from operating activities: |
||||||||
| Net loss |
$ |
( |
) |
$ |
( |
) | ||
| Adjustments to reconcile net loss to net cash used in operating activities: |
||||||||
| Depreciation |
||||||||
| Stock-based compensation |
||||||||
| Write-off of deferred IPO costs |
— |
|||||||
| Changes in operating assets and liabilities: |
||||||||
| Prepaid expenses and other assets |
( |
) |
( |
) | ||||
| Right-of-use |
||||||||
| Accounts payable |
||||||||
| Accrued expenses and other liabilities |
||||||||
| |
|
|
|
|||||
| Net cash used in operating activities |
( |
) |
( |
) | ||||
| |
|
|
|
|||||
| Cash flows from investing activities: |
||||||||
| Purchases of property and equipment |
( |
) |
( |
) | ||||
| |
|
|
|
|||||
| Net cash used in investing activities |
( |
) |
( |
) | ||||
| |
|
|
|
|||||
| Cash flows from financing activities: |
||||||||
| Issuance of convertible preferred stock, net of issuance costs |
— |
( |
) | |||||
| Deferred issuance costs related to merger / initial public offering |
( |
) |
( |
) | ||||
| Issuance of common stock |
||||||||
| |
|
|
|
|||||
| Net cash used in financing activities |
( |
) |
( |
) | ||||
| |
|
|
|
|||||
| Net decrease in cash, cash equivalents and restricted cash |
( |
) |
( |
) | ||||
| Cash, cash equivalents and restricted cash at the beginning of the period |
||||||||
| |
|
|
|
|||||
| Cash, cash equivalents and restricted cash at the end of the period |
$ |
$ |
||||||
| |
|
|
|
|||||
| Components of cash, cash equivalents and restricted cash: |
||||||||
| Cash and cash equivalents |
$ |
$ |
||||||
| Restricted cash |
||||||||
| |
|
|
|
|||||
| Total cash, cash equivalents and restricted cash |
$ |
$ |
||||||
| |
|
|
|
|||||
| Supplemental disclosure of non-cash operating activities: |
||||||||
| Deferred issuance costs related to initial public offering included in accounts payable |
$ |
— |
$ |
|||||
| |
|
|
|
|||||
| Deferred issuance costs related to initial public offering included in accrued liabilities |
$ |
— |
$ |
|||||
| |
|
|
|
|||||
| Deferred merger costs included in accounts payable |
$ |
$ |
— |
|||||
| |
|
|
|
|||||
| Deferred merger costs included in accrued liabilities |
$ |
$ |
— |
|||||
| |
|
|
|
|||||
| Lease liability obtained in exchange for right of use asset |
$ |
$ |
||||||
| |
|
|
|
|||||
The accompanying notes are an integral part of these financial statements
F-6
ENLIVEN THERAPEUTICS, INC.
NOTES TO FINANCIAL STATEMENTS
In connection with the closing of the Merger (as defined below) Enliven Therapeutics, Inc. changed its name to Enliven Inc. on February 23, 2023. For the purposes of these Notes to the Financial Statements, Enliven Therapeutics, Inc. is referring to the company prior to the Merger (as defined below).
1. Organization, Description of Business and Liquidity
Business
Enliven Therapeutics, Inc. (the Company) was incorporated in the State of Delaware on June 12, 2019 and is headquartered in Boulder, Colorado. The Company is a biopharmaceutical company focused on the discovery and development of small molecule inhibitors to help patients with cancer not only live longer, but better. The Company aims to address emerging unmet needs with a precision oncology approach that improves survival and enhances overall patient well-being. Its discovery process combines deep insights in clinically validated biological targets and differentiated chemistry with the goal of designing therapies for unmet needs.
Since its inception, the Company has devoted substantially all of its efforts to research and development activities, business planning, establishing and maintaining its intellectual property portfolio, hiring personnel, raising capital, and providing general and administrative support for these activities. To date, the Company has funded its operations primarily through private placements of its convertible preferred stock.
On October 13, 2022, the Company entered into an agreement and plan of merger (Merger Agreement) with Imara Inc. (Imara), a Delaware corporation and Iguana Merger Sub, Inc., a wholly-owned subsidiary of Imara (Merger Sub). Pursuant to the Merger Agreement, among other matters, and subject to the satisfaction or waiver of the conditions set forth in the Merger Agreement, Merger Sub merged with and into the Company, with the Company continuing as a wholly owned subsidiary of Imara and the surviving corporation of the merger (the Merger). Immediately prior to the closing of the Merger, certain new and current investors subscribed for the purchase of an aggregate of approximately $164.5 million of common stock of Enliven (the Financing). On February 23, 2023, Enliven closed the Merger with Imara Inc. Following the closing of the Merger, Imara Inc. changed its corporate name to Enliven Therapeutics, Inc.
Risks and uncertainties
The Company is subject to risks common to development-stage companies in the biotechnology industry including, but not limited to, risks of failure of preclinical studies and clinical trials, new technological innovations, protection of proprietary technology, dependence on key personnel, reliance on third-party organizations, risks of obtaining regulatory approval for any product candidate that it may develop, compliance with government regulations and the need to obtain additional financing.
The Company continues to closely monitor macroeconomic and geopolitical developments, including the global
COVID-19
pandemic, the Russia- Ukraine conflict and inflation. The extent of the impact of these developments on the Company’s business, operations and research and development timelines and plans remains uncertain, and will depend on numerous factors, including the impact, if any, on the Company’s personnel, responses of governmental entities, and the responses of third parties such as contract research organizations (CROs), contract manufacturing organizations (CMOs) and other third parties with whom the Company does business. Any prolonged material disruption to the Company’s employees or suppliers could adversely impact the Company’s development activities, financial condition and results of operations, including its ability to obtain financing. The Company is monitoring the potential impact of these developments on its business and financial statements. To date, the Company has not experienced material business disruptions or incurred impairment losses in the carrying values of its assets as a result of these developments, and it is not aware of any specific related event or circumstance that would require it to revise its estimates reflected in these financial statements. Liquidity considerations
In order to complete the development of our product candidates and to build the sales, marketing and distribution infrastructure that we believe will be necessary to commercialize our product candidates, if approved, we will require substantial additional capital. Until we can generate a sufficient amount of revenue from the commercialization of our product candidates, we may seek to raise any necessary additional capital through private or public equity or debt financings, loans or other capital sources, which could include income from collaborations, partnerships or other marketing, distribution, licensing or other strategic arrangements with third parties, or from grants. Because of the numerous risks and uncertainties associated with research, development and commercialization of product candidates, we are unable to estimate the exact amount and timing of our capital requirements. We do not expect to generate any meaningful revenue unless and until we obtain regulatory approval of and commercialize any of our product candidates, and we do not know when, or if, that will occur.
The Company has incurred significant losses and negative cash flows from operations since inception. As of December 31, 2022, the Company had an accumulated deficit of $82.9 million. The Company has incurred losses and negative cash flows from operations since inception, including net losses of $37.7 million and $24.7 million for the years ended December 31, 2022 and 2021, respectively. The Company expects that its operating losses and negative cash flows will continue for the foreseeable future as the Company continues to develop its product candidates. The Company currently expects that its cash and cash equivalents of $75.5 million as of December 31, 2022 will be sufficient to fund operating expenses and capital requirements for at least 12 months from the date the financial statements are issued.
Merger Agreement and Exchange Ratio
On October 13, 2022, the Company entered into the Merger Agreement with Imara, a Delaware corporation and Merger Sub. Pursuant to the Merger Agreement, among other matters, Merger Sub merged with and into the Company, with the Company continuing as a wholly owned subsidiary of Imara and the surviving corporation of the Merger. The Merger was intended to qualify for U.S. federal income tax purposes as a tax-free “reorganization” under the provisions of Section 368(a) of the Code and, in the event that former Enliven stockholders, including stockholders that participate in the Enliven
pre-closing
financing, are in “control” of Imara immediately after the effective time of the Merger (within the meaning of Section 368(c) of the Code), as a non-taxable
exchange of shares of Enliven common stock for shares of Imara common stock within the meaning of Section 351(a) of the Code, with the result that Enliven stockholders will generally not recognize taxable gain or loss for U.S. federal income tax purposes upon the exchange of Enliven common stock for Imara common stock pursuant to the Merger, except with respect to cash received in lieu of a fractional share of Imara common stock. Upon the closing of the Merger on February 23, 2023, (a) each outstanding share of Company common stock (including common stock issued upon the conversion of the Company’s preferred stock, and shares issued in the Financing) was converted into the right to receive a number of shares of Imara common stock (Imara Common Stock) (after giving effect to the 1-for-4 reverse stock split of Imara Common Stock in connection with the Merger) equal to the exchange ratio per the Merger Agreement; and (b) each of the then outstanding Company stock option that had not previously been exercised prior to the closing of the Merger was assumed by Imara.
Immediately prior to the closing of the Merger, and in order to provide the Company with additional capital for its development programs, certain new and current investors purchased an aggregate of approximately $164.5 million of common stock of Enliven.
The Merger and Financing were completed on February 23, 2023. The Merger has been accounted for as a reverse recapitalization under U.S. GAAP because the assets of Imara as of the effective date of the Merger are primarily cash and other eight of nine) of the initial members of the board of directors of the combined company; and (3) Enliven’s senior management holds all positions in senior management
non-operating
assets. Enliven was determined to be the accounting acquirer based upon the terms of the Merger and other factors including: (1) Enliven stockholders own a substantial majority of the voting rights in the combined company; (2) Enliven designated a majority (of
the combined company. F-8
2. Summary of Significant Accounting Policies
Basis of presentation
The accompanying financial statements have been prepared in conformity with generally accepted accounting principles in the United States of America (US GAAP). Any reference in these notes to applicable guidance is meant to refer to U.S. GAAP, as found in the Accounting Standards Codification, (ASC), and Accounting Standards Update, (ASU), of the Financial Accounting Standards Board (FASB).
Use of estimates
The preparation of financial statements in accordance with US GAAP requires management to make estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the financial statements, and the reported amounts of income and expense during the reporting period. The most significant estimates relate to the determination of fair value of the Company’s common stock and convertible preferred stock, determination of the fair value of the convertible preferred stock tranche liabilities and
stock-based
compensation. Management evaluates its estimates and assumptions on an ongoing basis using historical experience and other factors, including the current economic environment, and makes adjustments when facts and circumstances dictate. Cash and cash equivalents
The Company considers all highly liquid investments with an original maturity of three months or less when purchased to be cash equivalents. Cash and cash equivalents are recorded at cost, which approximates fair value. As of December 31, 2022 and 2021, cash and cash equivalents consisted primarily of checking and money market funds composed of US government obligations.
Restricted cash
The Company classifies all cash whose use is limited by contractual provisions as restricted cash. Restricted cash arises from the requirement for the Company to maintain cash of $54,000 as collateral for a sublease with the facility’s landlord. As of December 31, 2022 and 2021, $54 ,000 of restricted cash was recorded in restricted cash in the balance sheets.
Concentrations of credit risk and
off-balance
sheet risk The Company maintains its cash accounts and money market fund that at times exceed insured limits. As of December 31, 2022 and 2021, the Company’s cash balances exceeded those that are federally insured. To date, the Company has no t recognized any losses caused by uninsured balances.
Fair value measurements
Financial assets and liabilities recorded at fair value on a recurring basis in the balance sheets are categorized based upon the level of judgment associated with the inputs used to measure their fair values. Fair value is defined as the price the Company would receive to sell an investment in a timely transaction or pay to transfer a liability in a timely transaction with an independent buyer in the principal market, or in the absence of a principal market, the most advantageous market for the investment or liability. A framework is used for measuring fair value utilizing a three-tier hierarchy that prioritizes the inputs to valuation techniques used to measure fair value. The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1) and the lowest priority to unobservable inputs (Level 3).
The three levels of the fair value hierarchy are as follows:
| • | Level 1—Unadjusted quoted prices in active markets that are accessible at the measurement date for identical, unrestricted assets or liabilities; |
| • | Level 2—Quoted prices in markets that are not considered to be active or financial instrument valuations for which all significant inputs are observable, either directly or indirectly; and |
| • | Level 3—Prices or valuations that require inputs that are both significant to the fair value measurement and unobservable. |
Financial instruments are categorized in their entirety based on the lowest level of input that is significant to the fair value measurement. The assessment of the significance of a particular input to the fair value measurement requires judgment and considers factors specific to the investment. To the extent that the valuation is based on models or inputs that are less observable or unobservable in the market, the determination of fair value requires more judgment. Accordingly, the degree of judgment exercised by the Company in determining fair value is greatest for instruments categorized in Level 3.
The Company monitors the availability of inputs that are significant to the measurement of fair value to assess the appropriate categorization of financial instruments within the fair value hierarchy. Changes in economic conditions or model-based valuation techniques may require the transfer of financial instruments from one fair value level to another. In such instances, the Company’s policy is to recognize significant transfers between levels at the end of the reporting period. The significance of transfers between levels is evaluated based upon the nature of the financial instrument and size of the transfer relative to total net assets available for benefits.
The Company’s cash and cash equivalents, prepaid expenses and other current assets, accounts payable and accrued expenses and other current liabilities approximate their fair value due to their short maturities.
Deferred offering costs
Deferred offering costs, consisting of legal, accounting and other fees and costs relating to the Company’s previously planned Initial Public Offering (IPO) and the Merger were capitalized and recorded on the balance sheets. During the year ended December 31, 2022, the Company expensed its previously capitalized deferred offering costs related to the previously planned IPO, which totaled $1.7 million, to general and administrative expenses, in the statement of operations and comprehensive loss. Deferred offering costs capitalized as of December 31, 2022 and 2021 were $4.0 million and $1.7 million, respectively.
Property and equipment, net
Property and equipment are recorded at cost. Expenditures for repairs and maintenance are expensed as incurred. When assets are retired or disposed of, the assets and related accumulated depreciation are eliminated from the accounts, and any resulting gain or loss is included in the determination of net income or loss. Depreciation is calculated using the straight-line method over the estimated useful lives of the related assets. Leasehold improvements are amortized over the shorter of the lease term or the estimated useful life of the asset.
The Company’s property and equipment consist of laboratory equipment and employee-related computers with estimated useful lives of to five years .
Impairment of long-lived assets
The Company evaluates long-lived assets, which consist of laboratory equipment and computers, for impairment whenever events or changes in circumstances indicate that the carrying amount of such assets may not be recoverable. Recoverability of assets to be held and used is measured by a comparison of the carrying amount of an asset to the future undiscounted net cash flows expected to be generated by the asset. If such assets are considered to be impaired, the impairment to be recognized is measured by the amount by which the carrying amount of the asset exceeds the fair value of the asset. To date, no impairments have been recognized in the Company’s financial statements.
Leases
The Company elected to early adopt ASU asset (ROU) upon commencement of the lease using the implicit rate or a discount rate based on a credit-adjusted secured borrowing rate commensurate with the term of the lease. Operating lease assets represent a right to use an underlying asset for the lease term and operating lease liabilities represent an obligation to make lease payments arising from the lease. Operating lease liabilities with a term greater than one year and their corresponding assets are recognized on the balance sheet at the commencement date of the lease based on the present value of lease payments over the expected lease term. As the Company’s lease does not provide an implicit rate, the Company utilizes the appropriate incremental borrowing rate, determined as the rate of interest that the Company would have to pay to borrow on a collateralized basis over a similar term and in a similar economic environment. Lease cost is recognized on a straight-line basis over the lease term and variable lease payments are recognized as operating expenses in the period in which the obligation for those payments is incurred. Variable lease payments primarily include common area maintenance, utilities, real estate taxes, insurance, and other operating costs that are passed on from the lessor in proportion to the space leased by the Company. The Company has elected the practical expedient to not separate between lease and
No. 2016-02,
Leases (ASC 842) and its associated amendments as of January 1, 2020. In June 2020, the Company entered into a sublease agreement under which it leased laboratory and office facilities which the Company determined to be an operating lease. At the inception of a contractual arrangement, the Company determines whether the contract contains a lease by assessing whether there is an identified asset and whether the contract conveys the right to control the use of the identified asset in exchange for consideration over a period of time. If both criteria are met, the Company records the associated lease liability and corresponding right-of-use
right-of-use
non-lease
components. Operating ROU assets are reflected in ROU assets. Operating lease liabilities are reflected in accrued expenses and other current liabilities, and other
non-current
liabilities. Convertible preferred stock
The Company classifies convertible preferred stock outside of stockholders’ deficit on its balance sheet as the requirements of triggering a deemed liquidation event are not within the Company’s control. In the event of a deemed liquidation event, the proceeds from the event are distributed in accordance with liquidation preferences (Note 9). The Company records the issuance of convertible preferred stock at the issuance price less related issuance costs and less any discount arising on allocation of proceeds to one or more derivative features. The Company has not adjusted the carrying values of the convertible preferred stock to its liquidation preference because of the uncertainty as to whether a deemed liquidation event may occur.
Research and development expenses
The Company expenses research and development costs as incurred. Research and development expenses consist primarily of costs incurred for the discovery and development of its product candidates and include consultants and supplies to conduct clinical, preclinical, and
non-clinical
studies, costs to acquire, develop and manufacture supplies for preclinical and clinical testing and other studies, expenses incurred under agreements with contract research organizations, and salaries and related costs, including equity-based compensation, as well as depreciation and other allocated facility-related and overhead expenses. Advance payments for goods or services for future research and development activities are deferred and expensed as the goods are delivered or the related services are performed. The Company estimates clinical and preclinical study expenses based on the services performed pursuant to contracts with research institutions and clinical research organizations that conduct and manage preclinical studies and clinical trials on the Company’s behalf. In addition, clinical, preclinical, and
non-clinical
study materials are manufactured by contract manufacturing organizations. In accruing for these services, the Company estimates the time period over which services will be performed and the level of effort to be expended in each period. These estimates are based on communications with the third-party service providers and the Company’s estimates of accrued expenses and on information available at each balance sheet date. If the actual timing of the performance of services or the level of effort varies from the estimate, the Company will adjust the accrual accordingly. Stock-based compensation
The Company measures and records the expense related to stock-based payment awards based on the estimated grant date fair value of those awards. The Company recognizes stock-based compensation expense over the requisite service period of the individual award, generally equal to the vesting period and uses the straight-line method to recognize stock-based compensation. The Company uses the Black-Scholes option pricing model to determine the fair value of the stock awards. The Black-Scholes option pricing model requires the Company to make assumptions and judgements about the variables used in the calculations, including the fair value of common stock, expected term, expected volatility of its common stock, risk-free interest rate and expected dividend yield. As the stock-based compensation is based on awards ultimately expected to vest, it is reduced by forfeitures, which the Company accounts for as they occur.
The Company classifies equity-based compensation expense in the statement of operations and comprehensive loss in the same manner in which the award recipients’ payroll costs are classified or in which the award recipients’ service payments are classified.
Black-Scholes requires the use of subjective assumptions which determine the fair value of stock-based awards. These assumptions include:
| • | Fair Value of Common Stock—As there has been no public market for the Company’s common stock to date, the estimated fair value of the Company’s common stock has been determined by the board of directors as of the date of each option grant with input from management, considering the most recently available third-party valuation of common stock. |
| • | Expected Term—The expected term represents the period that the Company’s options are expected to be outstanding and is determined using the simplified method (based on the mid-point between the vesting date and the end of the contractual term). The Company has very limited historical information to develop reasonable expectations about future exercise patterns and post-vesting employment termination behavior for its stock option grants. |
| • | Expected Volatility—The expected stock price volatilities are estimated based on the historical and implied volatilities of comparable publicly traded companies as the Company does not have sufficient history of trading its common stock. |
| • | Risk-Free Interest Rate—The risk-free interest rates are based on U.S. Treasury yields in effect at the grant date for notes with comparable terms as the awards. |
| • | Expected Dividend Yield—The Company has never paid dividends on its common stock and has no plans to pay dividends on the Company’s common stock. Therefore, the Company used an expected dividend of |
The assumptions underlying these valuations represented the Company’s board and management’s best estimates,
which
involved inherent uncertainties and the application of management’s judgment. As a result, if the Company had used significantly different assumptions or estimates, the fair value of its stock-based compensation expense could be materially different. Income taxes
Income taxes are accounted for using the asset and liability method. Deferred tax assets and liabilities are recognized for the future tax consequences attributable to differences between the financial statement carrying amounts or existing assets and liabilities and their respective tax bases. Deferred tax assets and liabilities are measured using the enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in income in the period of enactment. Valuation allowances are established, when necessary, to reduce deferred tax assets to the amount expected to be realized.
The Company has generated net losses since inception and accordingly has not recorded a provision for income taxes.
The Company recognizes a tax benefit from an uncertain tax position if it is more likely than not that the tax position will be sustained upon examination by the tax authorities, based on the merits of the position. The Company’s policy is to recognize interest and penalties related to the underpayment of income taxes as a component of its provision for income taxes. To date, there have been no interest or penalties charged in relation to the unrecognized tax benefits.
Net loss per share
The Company calculates basic and diluted net loss per share attributable to common stockholders in conformity with the
two-class
method required for participating securities. Convertible preferred stock is a participating security in distributions of the Company. The net loss attributable to common stockholders is not allocated to the convertible preferred shares as the holders of convertible preferred shares do not have a contractual obligation to share in losses. Cumulative dividends on preferred shares are added to net loss to arrive at net loss available to common stockholders. Under the
two-class
method, basic net loss per share of common stock is computed by dividing net loss by the weighted-average number of shares of common stock outstanding during each period. The weighted-average number of shares of common stock outstanding used in the basic net loss per share calculation does not include unvested restricted common stock as these shares are considered contingently issuable shares until they vest. Diluted net loss per share of common stock includes the effect, if any, from the potential exercise or conversion of securities, such as convertible preferred stock, stock options and unvested early exercised common stock and unvested restricted common stock, which would result in the issuance of incremental shares of common stock. For diluted net loss per share, the weighted-average number of shares of common stock is the same for basic net loss per share due to the fact that when a net loss exists, dilutive securities are not included in the calculation as the impact is anti-dilutive. For all periods presented, basic and diluted net loss per share were the same, as any additional share equivalents would be anti-dilutive.
Segments
The Company operates in one segment and, accordingly, no segment disclosures have been presented herein. The Company’s chief executive officer, who is the chief operating decision maker, reviews financial information on an aggregate basis for allocating and evaluating financial performance.
Comprehensive income (loss)
Other comprehensive income (loss) is defined as the change in equity of a business enterprise during a period from transactions and other events and circumstances from
non-owner
sources. The Company did not have any items that required classification as other comprehensive income (loss). Emerging growth company status
The Company is an emerging growth company, as defined in the Jumpstart Our Business Startups Act of 2012 (JOBS Act). Under the JOBS Act, emerging growth companies can delay adopting new or revised accounting standards issued subsequent to the enactment of the JOBS Act, until such time as those standards apply to private companies. The Company has elected to use this extended transition period for complying with new or revised accounting standards that have different effective dates for public and private companies until the earlier of the date that it (i) is no longer an emerging growth company or (ii) affirmatively and irrevocably opts out of the extended transition period provided in the JOBS Act. As a result, these financial statements may not be comparable to companies that comply with the new or revised accounting pronouncements as of public company effective dates.
Recently issued accounting pronouncements adopted
In December 2019, the FASB issued ASU adopted on January 1, 2022 , and the adoption did no t have a material impact.
2019-12,
Simplifying the Accounting for Income Taxes (ASU 2019-12).
ASU 2019-12
eliminates certain exceptions related to the approach for intra-period tax allocation, the methodology for calculating income taxes in an interim period and the recognition of deferred tax liabilities for outside basis differences. It also clarifies and simplifies other aspects of the accounting for income taxes. This guidance was effective for fiscal years beginning after December 15, 2021. The Company F-14
3. Fair Value Measurements
The following tables set forth the fair value of the Company’s financial assets measured at fair value on a recurring basis and indicates the level within the fair value hierarchy utilized to determine such values (in thousands):
As of December 31, 2022 |
||||||||||||||||
Total |
Level 1 |
Level 2 |
Level 3 |
|||||||||||||
| Assets: |
||||||||||||||||
| US Treasury backed money market funds |
$ |
$ |
$ |
$ |
||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Total financial assets measured at fair value |
$ |
$ |
$ |
$ |
||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
As of December 31, 2021 |
||||||||||||||||
Total |
Level 1 |
Level 2 |
Level 3 |
|||||||||||||
| Assets: |
||||||||||||||||
| US Treasury backed money market funds |
$ |
$ |
$ |
$ |
||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Total financial assets measured at fair value |
$ |
$ |
$ |
$ |
||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Money market funds are highly liquid investments that are valued based on quoted market prices in active markets, which represent a Level 1 measurement within the fair value hierarchy.
F-15
4. Leases
Facility lease
In June 2020, the Company leased office and laboratory space under a sublease agreement for 6,782 square feet, which was set to expire on December 30, 2021 . In March 2021, the Company amended its sublease agreement, increasing its leased space by 2,495 square feet to 9,277 square feet and monthly rent to $12,000 . Upon the extension of the lease in March 2021, the lease was automatically extended to December 30, 2024 . Additionally, in January 2022 the Company amended its sublease, which increased the leased space by an additional 8,893 square feet commencing on May 1, 2022 , and the rental payments increased by an equally proportionate amount to reflect the increase in floor space. Further, in April 2022 the Company amended the sublease, which deferred the expansion for the additional space to July 1, 2022 . The monthly rent is subject to annual increases through the lease term. The Company is required to pay base rent expense as well as its proportionate share of the facilities operating expenses. The 4 %. The incremental borrowing rate was estimated based on the Company’s estimated borrowing rate on a collateralized loan. As of December 31, 2022, the remaining lease liability and right of use asset were $0.6 million and $0.6 million, respectively. As of December 31, 2021, the remaining lease liability and right of use asset were $0.5 million and $0.5 million, respectively.
non-lease
components, consisting primarily of common area maintenance, are paid separately based on actual costs incurred. Therefore, the variable non-lease
components were not included in the right of use asset and lease liability and are reflected as expense in the period incurred. The incremental borrowing rate used to calculate the Company’s right of use asset and lease liability is The Company recognized rent expense under the facility sublease for the years ended December 31, 2022 and 2021 of $0.2 As of December 31, 2022 the future minimum lease payments under the facilities operating sublease were as follows (in thousands):
As of December 31, 2022 |
||||
| Year ending December 31, |
||||
| 2023 |
$ |
|||
| 2024 |
||||
| |
|
|||
| Total minimum lease payments |
||||
| Less: amount representing interest |
||||
| |
|
|||
| Present value of lease liabilities |
||||
| Less: current portion of lease liabilities |
||||
| |
|
|||
| Lease liabilities, noncurrent |
$ |
|||
| |
|
|||
During the years ended December 31, 2022 and 2021, the Company recognized $0.3 million and $0.2 million in variable lease costs, respectively.
5. Property and Equipment, Net
Property and equipment, net consisted of the following (dollars in thousands):
Estimated Useful Life |
As of December 31, |
|||||||||||
in Years |
2022 |
2021 |
||||||||||
| Laboratory equipment |
$ |
$ |
||||||||||
| Computer equipment |
||||||||||||
| |
|
|
|
|||||||||
| Less: accumulated depreciation |
( |
) |
( |
) | ||||||||
| |
|
|
|
|||||||||
| Property and equipment, net |
$ |
$ |
||||||||||
| |
|
|
|
|||||||||
Depreciation expense for the years ended December 31, 2022 and 2021 was $0.2 million and $0.1 million, respectively.
6. Accrued Expenses and Other Current Liabilities
Accrued expenses and other current liabilities consisted of the following (in thousands):
As of December 31, |
||||||||
2022 |
2021 |
|||||||
| Accrued employee compensation costs |
$ |
$ |
||||||
| Accrued research and development costs |
||||||||
| Accrued deferred offering costs |
||||||||
| Lease liabilities |
||||||||
| Accrued legal and professional fees |
||||||||
| Other |
||||||||
| |
|
|
|
|||||
| Accrued expenses and other current liabilities |
$ |
$ |
||||||
| |
|
|
|
|
|
|
|
|
F-17
7. Commitments and Contingencies
Lease commitments
Litigation
Indemnification agreements
8. Common Stock
As of December 31, 2022 and 2021, the Company’s Amended and Restated Certificate of Incorporation authorized the Company to issue 26,264,364 0.0001 3,570,019 3,435,014 252,652 and 703,092 shares which were subject to repurchase, respectively. The liability related to shares subject to repurchase totaled $0.6 0.3 million and $0.4 million were recorded as other
non-current
liabilities as of December 31, 2022 and 2021, respectively. Each share of common stock entitles the holder to one vote on all matters submitted to a vote of the Company’s stockholders. Common stockholders are entitled to receive dividends, as may be declared by the Company’s board of directors, if any, subject to the preferential dividend rights of any convertible preferred stock. No
In the event of any liquidation or dissolution of the Company, the holders of common stock are entitled to the remaining assets of the Company legally available for distribution after the payment of the full liquidation preference for any convertible preferred stock.
The Company had the following shares of common stock reserved for future issuance:
As of December 31, |
||||||||
2022 |
2021 |
|||||||
| Conversion of preferred stock |
||||||||
| Issuance of common stock upon exercise of stock options |
||||||||
| Options available for grant under stock plan |
||||||||
| |
|
|
|
|||||
| Total common stock reserved for future issuance |
||||||||
| |
|
|
|
|||||
F-18
9. Convertible Preferred Stock
As of December 31, 2022 and 2021, the Company’s Amended and Restated Articles of Incorporation designated and authorized the Company to issue up to 61,730,064
Aggregate |
Proceeds Net |
|||||||||||||||||||
Shares |
Per Share |
Liquidation |
of Issuance |
|||||||||||||||||
Authorized |
Issued and |
Liquidation |
Amount |
Costs |
||||||||||||||||
Shares |
Outstanding |
Preference |
(in thousands) |
(in thousands) |
||||||||||||||||
| Series Seed convertible preferred stock |
$ |
$ |
$ |
|||||||||||||||||
| Series A convertible preferred stock |
$ |
|||||||||||||||||||
| Series B convertible preferred stock |
$ |
|||||||||||||||||||
| |
|
|
|
|
|
|
|
|||||||||||||
| Total convertible preferred stock |
$ |
$ |
||||||||||||||||||
| |
|
|
|
|
|
|
|
|||||||||||||
The Company’s convertible preferred stock have the following rights, preferences, privileges and restrictions:
Voting
as-converted
to common stock basis. Dividends
Liquidation preference
After payment of the liquidation preference to the holders of convertible preferred stock, the remaining assets of the Company shall be distributed ratably to the holders of common stock on a fully converted basis.
Redemption
Voluntary conversion
non-assessable
shares of common stock as is determined by dividing the applicable original issue price by the applicable conversion price in effect at the time of conversion. The original issue price of the Series Seed, Series A and Series B convertible preferred shares is $Automatic conversion
then-effective
conversion rate of such shares upon either (i) the closing of the sale of shares of the Company’s common stock to the public in a firm commitment underwritten public offering pursuant to an effective registration statement under the Securities Act of 1933, as amended, with proceeds of at least $10. Stock-Based Compensation
Equity Incentive Plan
non-statutory
stock options, stock appreciation rights, restricted stock, and restricted stock units to employees and non-employees
and incentive stock options only to employees. The 2019 Plan initially authorized grants of awards of up to Awards granted under the 2019 Plan expire no later than 10 years from the date of grant. For incentive stock options and 100 % of the estimated fair value on the date of grant. Options and restricted stock granted to employees typically vest over a four-year period but may be granted with different vesting terms.
non-statutory
stock options, the option exercise price will not be less than Stock Option Repricing
Effective August 9, 2022, the Company’s board of directors repriced certain previously granted and still outstanding vested and unvested stock option awards under the 2019 Plan. As a result, the exercise price for these awards was lowered to $2.48 per share, which was the fair value of the Company’s common stock on August 9, 2022. No other terms of the repriced stock options were modified, and the repriced stock options will continue to vest according to their original vesting schedules and will retain their original expiration dates. As a result of the repricing, 2,209,826 vested and unvested stock options outstanding as of August 9, 2022, with original exercise prices ranging from $4.68 to $7.56 , were repriced. The repricing on August 9, 2022 resulted in incremental stock-based compensation expense of $1.0 million, of which $0.3 million related to vested stock option awards and was expensed on the repricing date, and $0.7 million related to unvested stock option awards is being amortized on a straight-line basis over the remaining weighted-average vesting period of those awards of approximately 2.9 years.
The following table summarizes the stock plan activity:
Available for Grant |
Stock Options Outstanding |
Weighted- Average Exercise Price |
Weighted- Average Contractual Term (in years) |
Aggregate Intrinsic Value (in thousands) |
||||||||||||||||
| Outstanding - January 1, 2021 |
$ |
$ |
||||||||||||||||||
| Options granted |
( |
) |
$ |
|||||||||||||||||
| Options exercised and vested |
— |
( |
) |
$ |
||||||||||||||||
| |
|
|
|
|||||||||||||||||
| Outstanding - December 31, 2021 |
$ |
$ |
||||||||||||||||||
| Increase in option pool |
||||||||||||||||||||
| Options granted |
( |
) |
$ |
|||||||||||||||||
| Options exercised and vested |
— |
( |
) |
$ |
||||||||||||||||
| Options cancelled and forfeited |
( |
) |
$ |
|||||||||||||||||
| |
|
|
|
|||||||||||||||||
| Outstanding - December 31, 2022 |
$ |
$ |
||||||||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Exercisable - December 31, 2022 |
$ |
|||||||||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| Vested and expected to vest - December 31, 2022 |
$ |
|||||||||||||||||||
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
The total intrinsic value of exercised and vested incentive awards during the year ended December 31, 2022 was $0.1 million and is calculated on the difference between the exercise price and the fair value of the Company’s common stock as of the exercise date.
The Company records stock-based compensation expense on a straight-line basis over the vesting period. As of December 31, 2022, total compensation cost not yet recognized related to unvested stock options was $7.7 million, which is expected to be recognized over a weighted-average period of 2.43 years.
Restricted stock award activity
—Upon formation of the Company in June 2019, the Company issued 3.0 million shares in restricted common stock to the founders of the Company at $0.0003 per share. 25 % of the shares vested immediately upon issuance, with the remaining shares vesting evenly over 36 or 48 months. Vesting may be accelerated upon a change in control, as defined in the holder agreements. If the holders cease to have a business relationship with the Company, any unvested shares held by these individuals may be repurchased at their original purchase price. The unvested restricted stock is not considered outstanding for accounting purposes until the shares vest. As of December 31, 2022 and 2021, there were 41,499 and 438,045 shares subject to repurchase, respectively.
Additionally, between 2019 and 2020, the Company issued a total of 197,262 shares of restricted stock to employees and consultants for aggregate consideration of $27,000 . The purchase price of the restricted stock was the estimated fair value on the grant date. The restricted stock awards are subject to vesting over a period of to five years , and vesting may be accelerated upon a change in control, as defined in the holder agreements.
If the holders cease to have a business relationship with the Company, any unvested shares held by these individuals may be repurchased at their original purchase price. The unvested restricted stock is not considered outstanding for accounting purposes until the shares vest.
If
The following summarizes restricted stock activity:
Number of Shares |
Weighted- Average Grant Date Fair Value |
|||||||
| Unvested—December 31, 2020 |
$ |
|||||||
| Granted |
— |
— |
||||||
| Vested |
( |
) |
||||||
| Forfeited |
— |
— |
||||||
| |
|
|||||||
| Unvested—December 31, 2021 |
||||||||
| Granted |
— |
— |
||||||
| Vested |
( |
) |
||||||
| Forfeited |
— |
— |
||||||
| |
|
|||||||
| Unvested—December 31, 2022 |
$ |
|||||||
| |
|
|||||||
The aggregate fair value of restricted stock that vested during the year ended December 31, 2022 was $0.1 million. The weighted-average grant date fair value of restricted stock that vested during the year ended December 31, 2022 was $0.14 . Total intrinsic value of restricted stock as of December 31, 2022 was $0.2 million. As of December 31, 2022, total compensation cost not yet recognized related to unvested restricted stock was $4,000 , which is expected to be recognized over a weighted-average period of 1.12 years.
The aggregate fair value of restricted stock that vested during the year ended December 31, 2021 was $0.3 million. The weighted-average grant date fair value of restricted stock that vested during the year ended December 31, 2021 was $0.14 . Total intrinsic value of restricted stock as of December 31, 2021 was $3.6 million. As of December 31, 2021, total compensation cost not yet recognized related to unvested restricted stock was $7,000 , which is expected to be recognized over a weighted-average period of 2.04 years.
Stock-based compensation expense
Stock-based compensation expense is classified as follows (in thousands):
Year Ended December 31, |
||||||||
2022 |
2021 |
|||||||
| Research and development |
$ |
$ |
||||||
| General and administrative |
||||||||
| |
|
|
|
|||||
| Total stock-based compensation expense |
$ |
$ |
||||||
| |
|
|
|
|
|
|
|
|
The fair value of each stock option grant is estimated on the date of grant using a Black-Scholes model. The following summarizes the inputs used:
Year Ended December 31, | ||||
2022 |
2021 | |||
| Stock price |
$ |
$ | ||
| Expected term (years) |
||||
| Expected volatility |
||||
| Risk-free interest rate |
||||
| Expected dividend yield |
— |
— | ||
11. Income Taxes
The difference between the effective tax rate and the U.S. federal tax rate is as follows:
Year Ended |
||||||||
December 31, |
||||||||
2022 |
2021 |
|||||||
| Federal income tax |
( |
)% |
( |
)% | ||||
| State income tax, less federal benefits |
( |
)% |
( |
)% | ||||
| Permanent differences |
% |
% | ||||||
| Change in valuation allowance |
% |
% | ||||||
| Credits |
( |
)% |
( |
)% | ||||
| Other |
% |
% | ||||||
| |
|
|
|
|
|
|
|
|
| Effective tax rate |
% |
% | ||||||
| |
|
|
|
|
|
|
|
|
Significant components of the Company’s deferred income taxes consist of the following (in thousands):
As of December 31, |
||||||||
2022 |
2021 |
|||||||
| Deferred Tax Assets: |
||||||||
| Intangible asset basis differences |
$ |
$ |
||||||
| Net operating loss carryforwards |
||||||||
| Tax credit carryforwards |
||||||||
| Capitalized research and development costs |
||||||||
| Other |
||||||||
| |
|
|
|
|||||
| Total deferred tax assets |
||||||||
| Deferred Tax Liabilities: |
||||||||
| Fixed asset basis difference |
( |
) |
( |
) | ||||
| Goodwill differences |
( |
) |
( |
) | ||||
| |
|
|
|
|||||
| Total deferred tax liabilities |
( |
) |
( |
) | ||||
| Valuation allowance |
( |
) |
( |
) | ||||
| |
|
|
|
|||||
| Net deferred tax assets |
$ |
$ |
||||||
| |
|
|
|
|||||
Realization of tax assets is dependent upon future earnings, the timing and amount of which are uncertain. Accordingly, the U.S. net deferred tax assets have been fully offset by a valuation allowance. The changes in the valuation allowance for the years ended December 31, 2022 and 2021 were $10.1 million and $6.7 million, respectively.
As of December 31, 2022, the Company had federal net operating loss carryforwards of approximately $39.5 million, which has no expiration for federal tax purposes. As of December 31, 2022, the Company had California net operating loss carryforwards of approximately $65.8 million, which will begin to expire in 2039 for California tax purposes. At December 31, 2022, the Company also had Colorado net operating loss carryforwards of approximately $4,000 , which will begin to expire in 2041 for Colorado tax purposes.
Internal Revenue Code of 1986, as amended (IRC) Section 382 imposes limitations on the use of net operating loss carryforwards when the stock ownership of one or more 5 % stockholders (stockholders owning more than 5 % or more of the Company’s outstanding capital stock) has increased on a cumulative basis by more than 50 percentage points. There is a risk of an ownership change beyond the control of the Company that could trigger a limitation of the use of the loss carryover. As of December 31, 2022, the Company has not completed an analysis whether an ownership change occurred under Section 382, which, if it did occur, could substantially limit its ability in the future to utilize its net operating loss and other tax carryforwards.
As of December 31, 2022, the Company had Federal research and development credit carryforwards of approximately $0.4 million, which will begin to expire in 2041 . The Company had California research and development carryforwards of $0.2 million, which will not expire.
The Company adopted the provisions of FASB Accounting Standards Codification (ASC no 0.2 million, none of which if recognized would reduce the effective tax rate in a future period, due the Company’s full valuation allowance on U.S. net deferred tax assets. The Company does not expect that its uncertain tax positions will materially change in the next twelve months. The following table summarizes the changes to the Company’s unrecognized tax benefits (in thousands):
740-10),
Accounting for Uncertainty in Income Taxes, upon the date of incorporation. ASC 740-10
prescribes a comprehensive model for the recognition, measurement presentation and disclosure in financial statements of any uncertain tax positions that have been taken or expected to be taken on a tax return. It is the Company’s policy to include penalties and interest expense related to income taxes as a component of other expense and interest expense, respectively, as necessary. During the years ended December 31, 2022 and 2021, the Company had tax-related
penalties or interest. At December 31, 2022 the gross unrecognized tax benefit relating to research and development credits was $As of |
||||||||
December 31, |
||||||||
2022 |
2021 |
|||||||
| Balance, beginning of the period |
$ |
$ |
||||||
| Increase related to prior year positions |
||||||||
| Increase related to current year positions |
||||||||
| |
|
|
|
|||||
| Balance, end of the period |
$ |
$ |
||||||
| |
|
|
|
|||||
On August 9, 2022 and August 16, 2022, the Creating Helpful Incentives to Produce Semiconductors (CHIPS) Act and the Inflation Reduction Act (IRA), respectively, were signed into law. The CHIPS Act and IRA contain among other things, some income tax provisions that establish a corporate alternative minimum tax and provide tax incentives for semiconductor manufacturing and research. The Company has evaluated the current legislation and at this time, does not anticipate either to have a material impact on its financial statements.
The Tax Cuts and Jobs Act (TCJA) included a change in the treatment of research and development (R&D) expenditures for tax purposes under Section 174. Effective for tax years beginning after December 31, 2021, specified R&D expenditures must undergo a 5 -year amortization period for domestic spend and a 15 -year amortization period for foreign spend. Prior to the effective date (2021 tax year and prior), taxpayers were able to immediately expense R&D costs under Section 174(a) or had the option to capitalize and amortize R&D expenditures over a 5 -year recovery period under Section 174(b). The company has evaluated the current legislation at this time, and prepared the provision by following the treatment of R&D expenditures for tax purposes under Section 174.
F-27
12. 401(k) Savings Plan
The Company has a defined-contribution savings plan under IRC Section 401(k). The 401(k) Plan covers all employees who meet the defined minimum age and service requirements and allows participants to defer a portion of their annual compensation on a pretax basis. As of December 31, 2022 and 2021 the Company accrued no
13. Net Loss Per Share
Basic and diluted net loss per common share were calculated as follows (in thousands, except share and per share amounts):
Year Ended December 31, |
||||||||
2022 |
2021 |
|||||||
| Numerator: |
||||||||
| Net loss |
$ |
( |
) |
$ |
( |
) | ||
| |
|
|
|
|
|
|
|
|
| Denominator: |
||||||||
| Weighted-average common shares outstanding |
||||||||
| Less: weighted-average unvested common stock issued upon early exercise of common stock options |
( |
) |
( |
) | ||||
| Less: weighted-average unvested restricted shares of common stock |
( |
) |
( |
) | ||||
| |
|
|
|
|||||
| Weighted-average shares used to compute net loss per common share, basic and diluted |
||||||||
| |
|
|
|
|
|
|
|
|
| Net loss per share, basic and diluted |
$ |
( |
) |
$ |
( |
) | ||
| |
|
|
|
|
|
|
|
|
The Company’s potential dilutive securities, which include convertible preferred stock, unvested restricted stock, and common stock options, have been excluded from the computation of diluted net loss per share as the effect would be antidilutive. Therefore, the weighted-average number of common shares outstanding used to calculate both basic and diluted net loss per share is the same. The following potential dilutive securities, presented on an as converted basis, were excluded from the calculation of net loss per share due to their anti-dilutive effect:
Year Ended |
||||||||
December 31, |
||||||||
2022 |
2021 |
|||||||
| Convertible preferred stock (as converted) |
||||||||
| Stock options outstanding |
||||||||
| Unvested restricted stock |
||||||||
| |
|
|
|
|||||
| Total |
||||||||
| |
|
|
|
|||||
F-28
14. Subsequent Events
The Company evaluated subsequent events from December 31, 2022, the date of these financial statements, through June 23, 2023, which represents the date the financial statements were issued for events requiring recording or disclosure in the financial statements for the year ended December 31, 2022. The Company concluded that no events have occurred that would require recognition or disclosure in the financial statements, except as described below.
On February 23, 2023, Enliven closed the Merger with Imara Inc. Pursuant to the Merger Agreement, Merger Sub, a wholly owned subsidiary of Imara, merged with and into the Company, with the Company surviving as a wholly owned subsidiary of Imara Inc. Immediately prior to the closing of the Merger, investors in the Financing purchased shares of Enliven’s common stock totaling $164.5 million. Following the closing of the Merger, Imara Inc. changed its corporate name to Enliven Therapeutics, Inc.
In connection with the merger, a reverse stock split of Imara’s common stock was effectuated at a ratio of . In addition, each share of the Company’s common stock outstanding, including shares of the Company’s common stock that were issued pursuant to the Financing, converted into the right to receive a number of shares of Imara’s common stock based on an agreed upon ratio by the parties of approximately 0.2951 shares of Imara’s common stock for each share of the Company’s common stock. Historical common share figures of Enliven have been retroactively restated based on the exchange ratio of approximately 0.2951 .
F-29
Exhibit 99.2
UNAUDITED PRO FORMA COMBINED FINANCIAL INFORMATION
Explanatory Note
On October 13, 2022, Imara Inc. (“Imara” or the “Company”), Enliven Therapeutics, Inc. (“Enliven”), and a wholly owned subsidiary of Imara, Iguana Merger Sub, Inc. (“Merger Sub”) entered into an agreement and plan of merger (the “Merger Agreement”). Pursuant to the Merger Agreement, among other matters, Merger Sub merged with and into Enliven, with Enliven becoming a wholly-owned subsidiary of Imara and the surviving corporation of the merger, which transaction is referred to as the Merger. Following the closing of the Merger, Imara changed its name to Enliven Therapeutics, Inc. and Enliven Therapeutics, Inc. changed its name to Enliven Inc.
As previously disclosed, on February 23, 2023, Imara and Enliven completed the Merger, pursuant to the Merger Agreement.
At the effective time of the Merger, each share of Enliven’s common stock outstanding immediately prior to the effective time of the Merger, including shares of Enliven’s common stock that were issued pursuant to the Enliven pre-closing financing (as defined below), were converted into the right to receive a number of shares of the Company’s common stock based on the exchange ratio. The final exchange ratio is approximately 0.2951 shares of Imara’s common stock for each share of Enliven’s common stock, which gives effect to the Reverse Stock Split (as defined below). Each share of Enliven’s convertible preferred stock outstanding immediately prior to the effective time of the Merger was converted into shares of Enliven’s common stock in accordance with its terms, which then converted into the right to receive shares of the Company’s common stock along with all other shares of Enliven’s common stock as described above. Under the exchange ratio formula in the Merger Agreement, the Enliven equity holders immediately before the effective time of the Merger owned approximately 84% of the outstanding capital stock of Imara on a fully-diluted basis, and the stockholders of Imara immediately before the effective time of the Merger owned approximately 16% of the outstanding capital stock of Imara on a fully-diluted basis.
The Merger
On February 23, 2023, the Company filed an amendment to its Restated Certificate of Incorporation with the Secretary of State of the State of Delaware to effect the reverse stock split of its common stock, such that approximately every 4 shares of the Company’s common stock held by a stockholder immediately prior to the reverse stock split were combined and reclassified into 1 share of the Company’s common stock (the “Reverse Stock Split”). Except where otherwise indicated in these pro forma financial statements, all share and per share amounts of Imara have been adjusted retroactively to reflect the Reverse Stock Split as if it had occurred at the beginning of the earliest period presented for pro forma purposes only.
The Merger closed on February 23, 2023 pursuant to the Merger Agreement. At the closing of the Merger, the Company issued an aggregate of 34,426,351 shares of its common stock to the former Enliven stockholders, in exchange for all of the shares of Enliven common stock issued and outstanding immediately prior to the Merger, based on an exchange ratio of approximately 0.2951 with Enliven surviving as a wholly-owned subsidiary of the Company. In connection with the closing of the Merger, and in accordance with the terms of the Merger Agreement, the Company acquired net cash and cash equivalents from Imara of approximately $80.5 million. In addition, each outstanding and unexercised option to purchase shares of Enliven common stock granted to an individual who continued as a service provider to Enliven at the effective time of the Merger was assumed by the Company and converted into an option to purchase shares of the Company’s common stock, with necessary adjustments to reflect the exchange ratio.
The issuance of the shares of the Company’s common stock to the former stockholders of Enliven was registered with the SEC on the Company’s Registration Statement on Form S-4, as amended (File No. 333-268300).
Enliven Pre-closing Financing
On October 13, 2022, immediately prior to the execution and delivery of the Merger Agreement, Enliven entered into a common stock purchase agreement with certain investors, pursuant to which the investors agreed to purchase approximately 42.8 million shares of Enliven’s common stock, par value $0.0001 per share (the “Enliven pre-closing financing”).
On February 23, 2023, Enliven completed the pre-closing financing, in which Enliven issued approximately 42.8 million shares of Enliven common stock at a price of $3.84 per share, for aggregate gross proceeds of approximately $164.5 million, net of issuance costs of $4.7 million.
Unaudited Pro Forma Combined Financial Information
The following unaudited pro forma combined financial information gives effect to the Transaction Accounting Adjustments, which consist of the (i) Merger, (ii) the Enliven pre-closing financing, and (iii) the Reverse Stock Split.
In the unaudited pro forma combined financial statements, the Merger has been accounted for as a reverse recapitalization under U.S. generally accepted accounting principles (“U.S. GAAP”) because the assets of Imara as of the effective date of the Merger are primarily cash and other non-operating assets. Enliven was determined to be the accounting acquirer based upon the terms of the Merger and other factors including: (1) Enliven stockholders will own a substantial majority of the voting rights in the combined company; (2) Enliven will designate a majority (eight of nine) of the initial members of the board of directors of the combined company; and (3) Enliven’s senior management will hold all positions in senior management of the combined company.
As a result of Enliven being treated as the accounting acquirer, Enliven’s assets and liabilities are recorded at their pre-combination carrying amounts and the historical operations that are reflected in the unaudited pro forma combined financial information of Imara will be those of Enliven. Imara’s assets and liabilities will be measured and recognized at their fair values as of the effective date of the Merger, and combined with the assets, liabilities, and results of operations of Enliven after the consummation of the Merger. As a result, upon consummation of the Merger, the historical financial statements of Enliven will become the historical consolidated financial statements of the combined company.
The unaudited pro forma combined balance sheet data as of March 31, 2023 assumes that the Merger took place on March 31, 2023 and combines the Imara and Enliven historical balance sheets as of March 31, 2023. The unaudited pro forma combined statement of operations data for the three-month period ended March 31, 2023 and for the year ended December 31, 2022 gives effect to the Merger as if it took place on January 1, 2022 and combines the Imara and Enliven historical statement of operations for the periods presented.
The historical financial statements of Imara and Enliven have been adjusted to give pro forma effect to reflect the Transaction Accounting Adjustments in accordance with U.S. GAAP. The adjustments presented on the unaudited pro forma combined financial statements have been identified and presented to provide relevant information necessary for an accurate understanding of the combined company upon consummation of the Merger.
The unaudited pro forma combined financial information is based on assumptions and adjustments that are described in the accompanying notes, and is for illustrative purposes only. The unaudited pro forma combined financial information should not be relied upon as being indicative of the historical results that would have been achieved had the companies always been combined or the future results that the combined company will experience. The actual amounts recorded as of the completion of the Merger may differ materially from the information presented in these unaudited pro forma combined financial information as a result, if any, of the amount of cash used by Imara’s operations between the signing and closing of the Merger Agreement, and other changes in Imara’s assets and liabilities that occur prior to the completion of the Merger.
The unaudited pro forma combined financial information, including the notes thereto, should be read in conjunction with the separate historical consolidated financial statements of Imara and Enliven incorporated by reference in this information statement.
Unaudited Pro Forma Combined Balance Sheet
As of March 31, 2023
(in thousands)
| Enliven | IMARA | Transaction Accounting Adjustments |
Note 4 | Pro Forma Combined Total |
||||||||||||||||
| Assets | ||||||||||||||||||||
| Current assets: |
||||||||||||||||||||
| Cash and cash equivalents |
$ | 292,102 | $ | — | — | $ | 292,102 | |||||||||||||
| Prepaid expense and other current assets |
5,901 | — | — | 5,901 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Total current assets |
298,003 | — | — | 298,003 | ||||||||||||||||
| Property and equipment, net |
853 | — | — | 853 | ||||||||||||||||
| Right-of-use asset |
551 | — | — | 551 | ||||||||||||||||
| Restricted cash |
54 | — | — | 54 | ||||||||||||||||
| Other assets |
3,405 | — | — | 3,405 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Total assets |
$ | 302,866 | $ | — | — | $ | 302,866 | |||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Liabilities and stockholders’ equity | ||||||||||||||||||||
| Current liabilities: |
||||||||||||||||||||
| Accounts payable |
$ | 5,860 | $ | — | $ | — | $ | 5,860 | ||||||||||||
| Accrued expense and other current liabilities |
5,082 | — | — | 5,082 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Total current liabilities |
10,942 | — | — | 10,942 | ||||||||||||||||
| Long-term liabilities |
508 | — | — | 508 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Total liabilities |
11,450 | — | — | 11,450 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Stockholders’ equity (deficit): |
||||||||||||||||||||
| Preferred stock |
— | — | — | — | ||||||||||||||||
| Common stock |
41 | — | — | 41 | ||||||||||||||||
| Additional paid-in capital |
388,963 | — | — | 388,963 | ||||||||||||||||
| Accumulated deficit |
(97,588 | ) | — | — | (97,588 | ) | ||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Total stockholders’ equity |
291,416 | — | — | 291,416 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Total liabilities and stockholders’ equity |
$ | 302,866 | $ | — | $ | — | $ | 302,866 | ||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
Unaudited Pro Forma Combined Statement of Operations
For the Three Months Ended March 31, 2023
(in thousands, except for share and per share amounts)
| Enliven | IMARA | Transaction Accounting Adjustments |
Note 4 | Pro Forma Combined Total |
||||||||||||||||
| Operating expenses |
||||||||||||||||||||
| Research and development |
$ | 11,880 | $ | 104 | $ | — | $ | 11,984 | ||||||||||||
| General and administrative |
4,538 | 12,094 | — | 16,632 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Total operating expenses |
16,418 | 12,198 | — | 28,616 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Loss from operations |
(16,418 | ) | (12,198 | ) | — | (28,616 | ) | |||||||||||||
| Interest income |
1,694 | 602 | — | 2,296 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Total other income (expense), net |
1,694 | 602 | — | 2,296 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Net loss and comrehensive loss |
(14,724 | ) | (11,596 | ) | — | (26,320 | ) | |||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Net loss per share, basic and diluted |
$ | (0.80 | ) | $ | — | $ | — | $ | (1.42 | ) | ||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
| Weighted-average shares outstanding, basic and diluted |
18,514,644 | — | — | 18,514,644 | ||||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||||
Unaudited Pro Forma Combined Statement of Operations
For the Year Ended December 31, 2022
(in thousands, except for share and per share amounts)
| Enliven | IMARA | Transaction Accounting Adjustments |
Note 4 |
Pro Forma Combined Total |
||||||||||||||
| Operating expenses |
||||||||||||||||||
| Research and development |
$ | 31,022 | $ | 18,940 | $ | (17,692 | ) | (d) | $ | 32,270 | ||||||||
| General and administrative |
7,769 | 15,330 | 3,564 | (b)(c) | 26,663 | |||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
| Total operating expenses |
38,791 | 34,270 | (14,128 | ) | 58,933 | |||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
| Gain on sale of asset |
— | 35,000 | — | 35,000 | ||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
| Loss from operations |
(38,791 | ) | 730 | 14,128 | (23,933 | ) | ||||||||||||
| Other expense |
— | (97 | ) | — | (97 | ) | ||||||||||||
| Interest income |
1,129 | 943 | — | 2,072 | ||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
| Total other income (expense), net |
1,129 | 846 | — | 1,975 | ||||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
| Net loss (income) before income tax provision |
(37,662 | ) | 1,576 | 14,128 | (21,958 | ) | ||||||||||||
| Income tax provision |
— | (88 | ) | — | (88 | ) | ||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
| Net loss (income) |
$ | (37,662 | ) | $ | 1,488 | $ | 14,128 | $ | (22,046 | ) | ||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
| Net loss (income) share attributable to common stockholders, basic and diluted |
$ | (3.56 | ) | $ | 0.06 | $ | — | $ | (0.54 | ) | ||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
| Weighted average common shares outstanding, basic and diluted |
10,586,983 | 26,385,567 | 3,632,417 | (a) | 40,604,967 | |||||||||||||
|
|
|
|
|
|
|
|
|
|||||||||||
NOTES TO UNAUDITED PRO FORMA COMBINED FINANCIAL INFORMATION
1. Basis of Presentation
The unaudited pro forma combined financial information was prepared in accordance with U.S. GAAP and pursuant to the rules and regulations of Article 11 of Regulation S-X. The unaudited pro forma combined balance sheet as of March 31, 2023 was prepared using the historical consolidated balance sheets of Imara and Enliven as of March 31, 2023. The unaudited pro forma combined statement of operations for the three months ended March 31, 2023 and for the year ended December 31, 2022 were prepared using the historical statements of operations and comprehensive loss of Imara and Enliven for the three months ended March 31, 2023 and for the year ended December 31, 2022, respectively, and gives effect to the Merger as if it occurred on January 1, 2022.
For accounting purposes, Enliven is considered to be the acquirer, and the Merger was accounted for as a reverse recapitalization of Imara by Enliven because upon the closing of the Merger, the pre-combination assets of Imara were primarily cash.
Under reverse recapitalization accounting, the assets and liabilities of Imara were recorded, as of the date of the Merger, at their fair value. No goodwill or intangible assets were recognized and any excess consideration transferred over the fair value of the net assets of Imara, following determination of the actual purchase consideration for Imara are reflected as a reduction to additional paid-in capital. Consequently, the financial statements of Enliven reflect the operations of the acquirer for accounting purposes together with a deemed issuance of shares, equivalent to the shares held by the former stockholders of the legal acquirer and a recapitalization of the equity of the accounting acquirer. The accompanying unaudited pro forma combined financial information is derived from the historical financial statements of Imara and Enliven, and includes adjustments to give pro forma effect to reflect the accounting for the transaction in accordance with U.S. GAAP. The historical financial statements of Enliven shall become the historical financial statements of the combined company.
To the extent there are significant changes to the business following completion of the Merger, the assumptions and estimates set forth in the unaudited pro forma consolidated financial information could change significantly. Accordingly, the pro forma adjustments are subject to further adjustment as additional information becomes available and as additional analyses are conducted following the completion of the Merger. There can be no assurances that these additional analyses will not result in material changes to the estimates of fair value.
2. Purchase Price
The accompanying unaudited pro forma combined financial information reflects a purchase price of approximately $168.8 million, which consists of the following (in thousands, except share and per share amounts):
| Estimated number of common shares of the combined company to be owned by IMARA stockholders (1) |
6,625,176 | |||
| Multiplied by the fair value per share of IMARA common stock (2) |
$ | 25.28 | ||
|
|
|
|||
| Estimated fair value of IMARA common stock issued |
167,484 | |||
| Estimated fair value of stock options and restricted stock units attributable to precombination services (3) |
1,350 | |||
|
|
|
|||
| Estimated purchase price |
$ | 168,834 | ||
|
|
|
| (1) | Reflects the number of shares of the combined company that Imara equity holders owned as of the closing pursuant to the Merger Agreement. This amount is calculated for purposes of the unaudited pro forma combined financial information, based on the shares of Imara’s common stock outstanding as of February 23, 2023. |
| (2) | Reflects the assumed purchase price per share of Imara common stock, which is the closing price of Imara’s common stock on February 23, 2023. |
| (3) | Reflects the estimated acquisition-date fair value of the assumed Imara equity awards attributable to pre-combination services. |
3. Shares of Imara Common Stock Issued to Enliven’s Stockholders upon Closing of the Merger
Prior to the Merger, all outstanding convertible preferred stock of Enliven were converted into common stock of Enliven. At the effective time of the Merger, all outstanding shares of Enliven’s common stock were converted into the right to receive shares of Imara common stock as consideration for the Merger, based on the exchange ratio. The final exchange ratio for purposes of the unaudited pro forma combined financial information was derived on a fully-diluted basis as of February 23, 2023 using a stipulated value of Enliven of approximately $489.1 million (including the Enliven pre-closing financing discussed above) and of Imara of approximately $90.5 million. Based on the exchange ratio of approximately 0.2951 determined in accordance with the terms of the Merger Agreement, Imara issued 34,426,394 shares of common stock to the stockholders of Enliven in the Merger, determined as follows:
| Shares | ||||
| Enliven: |
||||
| Enliven common shareholders |
54,927,965 | |||
| Enliven convertible preferred stock |
61,730,064 | |||
|
|
|
|||
| Total Enliven common equivalent shares pre-close |
116,658,029 | |||
| Exchange ratio |
0.2951 | |||
|
|
|
|||
| Total Enliven merger common shares |
34,426,394 | |||
|
|
|
|||
The exchange ratio is calculated based on the Reverse Stock Split of Imara common stock.
4. Pro Forma Adjustments
The unaudited pro forma combined financial information includes pro forma adjustments that reflect Transaction Accounting Adjustments, as well as other adjustments deemed to be directly related to the Merger, irrespective of whether or not such adjustments are deemed to be recurring.
Based on Enliven management’s review of Imara’s summary of significant accounting policies, the nature and amount of any adjustments to the historical financial statements of Imara to conform to the accounting policies of Enliven are not expected to be significant.
The pro forma adjustments, based on preliminary estimates that may change significantly as additional information is obtained, are as follows:
| (a) | The pro forma combined basic and diluted earnings per share have been adjusted to reflect the pro forma net loss for the year ended December 31, 2022. In addition, the number of shares used in calculating the pro forma combined basic and diluted net loss per share has been adjusted to reflect the total number of shares of common stock of the combined company outstanding as of the Merger closing date, including the shares to be issued in the Enliven pre-closing financing. The following table presents the calculation of the pro forma weighted average number of common stock outstanding after giving effect to the Reverse Stock Split for Imara shares and application of the exchange ratio for Enliven shares: |
| December 31, 2022 | ||||
| Historical Enliven weighted-average shares of common stock outstanding |
10,586,983 | |||
| Impact of Enliven’s convertible preferred stock assuming conversion as of January 1, 2022 |
61,730,064 | |||
| Impact of Enliven’s common stock purchase agreement (Financing Transaction) assuming issuance as of January 1, 2022 |
42,827,612 | |||
|
|
|
|||
| Subtotal |
115,144,659 | |||
| Application of exchange ratio to historical Enliven weighted-average shares outstanding |
0.2951 | |||
|
|
|
|||
| Adjusted Enliven weighted-average shares outstanding (after giving effect to the Exchange Ratio) |
33,979,790 | |||
| Historical IMARA weighted-average shares of common stock outstanding |
6,571,816 | |||
| Impact of IMARA common stock related to stock units that accelerated vesting, reflected as having occurred January 1, 2022 |
53,361 | |||
|
|
|
|||
| Total weighted average shares outstanding |
40,604,967 | |||
|
|
|
|||
| (b) | To reflect the post combination stock-based compensation expense of $1.2 million, as a result of the accelerated vesting of certain Imara options, as a result of the Merger under the original award terms, as general and administrative expense on the unaudited pro forma combined statement of operations, and an increase in additional paid-in capital and accumulated deficit on the unaudited pro forma balance sheet. |
| (c) | To reflect Imara’s compensation expense of $2.4 million related to change-in-control severance payments resulting from pre-existing employment agreements that will be payable in cash in connection with the Merger but were not incurred as of December 31, 2022, as an increase to accrued expense and other current liabilities and accumulated deficit in the unaudited pro forma combined balance sheet. Imara’s compensation costs of $2.4 million are reflected as general and administrative expense in the unaudited pro forma combined statement of operations for the year ended December 31, 2022. |
| (d) | To reflect the elimination of direct external R&D expenses related to the IMR-687 program which were sold by Imara in an asset sale. Such R&D expenses were incurred and included in the Imara historical consolidated statement of operations for the year ended December 31, 2022. |