Stocks
PRLD Prelude Therapeutics Inc

PRLD

Prelude Therapeutics Inc

Company with tickers: PRLD

CIK

1678660

CUSIP

74065P101

Shares Outstanding

64,917,172

13F Activity (30d)

55 filings 54 filers

Date	Insider	Role	Type	Shares	Price	Value	After
2026-05-01	Morris Charles Q	Chief Medical Officer	Award	450,000	$4.70	$2,115,000	450,000
2026-04-27	RA CAPITAL MANAGEMENT, L.P.	Director	Other	1,407,000	—	—	1,407,000
2026-04-27	RA CAPITAL MANAGEMENT, L.P.	Director	Other	1,407,000	—	—	6,475,882
2026-04-21	Bonita David P	Director, 10% Owner	Other	526,300	—	—	526,300
2026-04-21	Bonita David P	Director, 10% Owner	Buy	1,126,126	$4.44	$4,999,999	1,126,126
2026-04-21	Bonita David P	Director, 10% Owner	Buy	1,689,189	$4.44	$7,499,999	11,808,945
2026-04-21	ORBIMED ADVISORS LLC	10% Owner	Other	526,300	—	—	526,300
2026-04-21	ORBIMED ADVISORS LLC	10% Owner	Buy	1,126,126	$4.44	$4,999,999	1,126,126
2026-04-21	ORBIMED ADVISORS LLC	10% Owner	Buy	1,689,189	$4.44	$7,499,999	11,808,945
2026-04-21	BAKER BROS. ADVISORS LP	Director, 10% Owner	Buy	2,137,651	$4.44	$9,490,957	20,105,994
2026-04-21	BAKER BROS. ADVISORS LP	Director, 10% Owner	Buy	114,601	$4.44	$508,817	1,678,273
2026-04-21	RA CAPITAL MANAGEMENT, L.P.	Director	Other	7,882,882	—	—	7,882,882
2026-04-15	Morris Charles Q	Chief Medical Officer	Other	0	—	—	0
2026-03-05	Brusky Sean P.	Chief Business Officer	Other	0	—	—	0
2026-03-05	Brusky Sean P.	Chief Business Officer	Other	0	—	—	0
2026-03-05	Brusky Sean P.	Chief Business Officer	Other	100,000	—	—	100,000
2026-03-05	Brusky Sean P.	Chief Business Officer	Other	0	—	—	0
2026-02-04	Lim Bryant David	CLO, CFO, Corp Sec.	Award	275,000	—	—	275,000
2026-02-04	Vaddi Krishna	Director, CEO	Award	837,000	—	—	837,000
2026-02-04	Combs Andrew	Chief Chemistry Officer	Award	230,000	—	—	230,000
2026-02-04	Scherle Peggy	Chief Scientific Officer	Award	230,000	—	—	230,000
2025-11-05	Sandor Victor	Director	Award	121,285	—	—	121,285
2025-10-17	Dorton Katina	Director	Award	76,000	—	—	76,000
2025-10-17	Dorton Katina	Director	Other	0	—	—	0
2025-10-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	90,272
2025-10-04	Huang Jane	CMO, Hematology	Tax	3,355	$1.47	$4,932	86,917
2025-10-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	18,750
2025-07-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	84,252
2025-07-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	28,125
2025-07-04	Huang Jane	CMO, Hematology	Tax	3,355	$0.79	$2,664	80,897
2025-06-12	FRIEDMAN PAUL A	Director	Award	38,000	—	—	38,000
2025-06-12	Bonita David P	Director, 10% Owner	Award	38,000	—	—	38,000
2025-06-12	Babler Martin	Director	Award	38,000	—	—	38,000
2025-06-12	BAKER BROS. ADVISORS LP	Director, 10% Owner	Award	76,000	—	—	76,000
2025-06-12	BAKER BROS. ADVISORS LP	Director, 10% Owner	Award	76,000	—	—	76,000
2025-06-12	Sandor Victor	Director	Award	38,000	—	—	38,000
2025-06-12	Dier Mardi	Director	Award	38,000	—	—	38,000
2025-06-12	Scherer Paul C	Director	Other	0	—	—	0
2025-04-04	Huang Jane	CMO, Hematology	Tax	3,355	$0.68	$2,265	74,877
2025-04-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	37,500
2025-04-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	78,232
2025-03-25	Combs Andrew	Chief Chemistry Officer	Buy	100,000	$0.69	$69,250	480,123
2025-03-25	Vaddi Krishna	Director, CEO	Other	551,774	—	—	551,774
2025-03-25	Vaddi Krishna	Director, CEO	Other	142,553	—	—	142,553
2025-03-25	Vaddi Krishna	Director, CEO	Buy	675,000	$0.69	$467,438	1,999,296
2025-03-25	Vaddi Krishna	Director, CEO	Other	551,776	—	—	551,776
2025-03-25	Vaddi Krishna	Director, CEO	Other	423,655	—	—	423,655
2025-03-21	Vaddi Krishna	Director, CEO	Buy	15,000	$0.73	$10,959	1,324,296
2025-03-20	Vaddi Krishna	Director, CEO	Other	423,655	—	—	423,655
2025-03-20	Vaddi Krishna	Director, CEO	Other	142,553	—	—	142,553
2025-03-20	Vaddi Krishna	Director, CEO	Other	551,776	—	—	551,776
2025-03-20	Vaddi Krishna	Director, CEO	Other	551,774	—	—	551,774
2025-03-20	Vaddi Krishna	Director, CEO	Buy	5,416	$0.73	$3,950	1,309,296
2025-03-17	Vaddi Krishna	Director, CEO	Buy	9,106	$0.75	$6,829	1,303,880
2025-03-14	Vaddi Krishna	Director, CEO	Other	423,655	—	—	423,655
2025-03-14	Vaddi Krishna	Director, CEO	Other	551,774	—	—	551,774
2025-03-14	Vaddi Krishna	Director, CEO	Other	551,776	—	—	551,776
2025-03-14	Vaddi Krishna	Director, CEO	Other	142,553	—	—	142,553
2025-03-14	Vaddi Krishna	Director, CEO	Buy	29,999	$0.75	$22,631	1,294,774
2025-03-13	Vaddi Krishna	Director, CEO	Buy	50,000	$0.72	$35,820	1,264,775
2025-03-12	Vaddi Krishna	Director, CEO	Other	142,553	—	—	142,553
2025-03-12	Vaddi Krishna	Director, CEO	Other	551,774	—	—	551,774
2025-03-12	Vaddi Krishna	Director, CEO	Other	423,655	—	—	423,655
2025-03-12	Vaddi Krishna	Director, CEO	Buy	47,500	$0.71	$33,744	1,214,775
2025-03-12	Vaddi Krishna	Director, CEO	Other	551,776	—	—	551,776
2025-02-04	Lim Bryant David	CLO, CFO, Corp Sec.	Award	200,000	—	—	200,000
2025-02-04	Scherle Peggy	Chief Scientific Officer	Award	175,000	—	—	175,000
2025-02-04	Combs Andrew	Chief Chemistry Officer	Award	175,000	—	—	175,000
2025-02-04	Huang Jane	CMO, Hematology	Award	200,000	—	—	200,000
2025-02-04	Vaddi Krishna	Director, CEO	Award	496,000	—	—	496,000
2025-01-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	46,875
2025-01-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	72,716
2025-01-04	Huang Jane	CMO, Hematology	Tax	3,859	$1.39	$5,364	68,857
2024-12-31	Vaddi Krishna	Director, CEO	Other	1,167,275	—	—	1,167,275
2024-12-31	Vaddi Krishna	Director, CEO	Other	551,776	—	—	551,776
2024-12-31	Vaddi Krishna	Director, CEO	Buy	5,000	$1.21	$6,044	142,553
2024-12-31	Vaddi Krishna	Director, CEO	Other	551,774	—	—	551,774
2024-12-31	Vaddi Krishna	Director, CEO	Other	423,655	—	—	423,655
2024-12-30	Vaddi Krishna	Director, CEO	Other	1,167,275	—	—	1,167,275
2024-12-30	Vaddi Krishna	Director, CEO	Other	423,665	—	—	423,665
2024-12-30	Vaddi Krishna	Director, CEO	Buy	10,000	$1.20	$12,000	137,553
2024-12-30	Vaddi Krishna	Director, CEO	Other	551,776	—	—	551,776
2024-12-30	Vaddi Krishna	Director, CEO	Other	551,774	—	—	551,774
2024-12-23	Combs Andrew	Chief Chemistry Officer	Buy	60,000	$1.37	$82,002	377,623
2024-12-20	Combs Andrew	Chief Chemistry Officer	Buy	3,075	$1.15	$3,536	317,623
2024-12-19	Lim Bryant David	CLO, CFO, Corp Sec.	Buy	25,000	$0.91	$22,638	27,400
2024-12-19	Vaddi Krishna	Director, CEO	Buy	6,888	$0.89	$6,116	127,553
2024-12-18	Vaddi Krishna	Director, CEO	Other	551,774	—	—	551,774
2024-12-18	Vaddi Krishna	Director, CEO	Other	423,665	—	—	423,665
2024-12-18	Vaddi Krishna	Director, CEO	Other	551,776	—	—	551,776
2024-12-18	Vaddi Krishna	Director, CEO	Buy	100,000	$0.93	$93,210	1,167,275
2024-10-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	66,690
2024-10-04	Huang Jane	CMO, Hematology	Tax	3,349	$2.00	$6,698	63,341
2024-10-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	56,250
2024-07-04	Huang Jane	CMO, Hematology	Tax	3,347	$3.60	$12,049	57,315
2024-07-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	60,662
2024-07-04	Huang Jane	CMO, Hematology	Convert	9,375	—	—	65,625
2024-06-14	BAKER BROS. ADVISORS LP	Director, 10% Owner	Award	23,500	—	—	23,500
2024-06-14	BAKER BROS. ADVISORS LP	Director, 10% Owner	Award	23,500	—	—	23,500
2024-06-14	Sandor Victor	Director	Award	23,500	—	—	23,500