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PRME · Prime Medicine, Inc.

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$3.70 -0.01 (-0.27%) At close · Sep 4
Russell 2000 member Rebalance outlook locked
Going-concern doubt — flagged Aug 6, 2026

Substantial doubt about the company's ability to continue as a going concern.

“As a result, we concluded that substantial doubt exists about our ability to continue as a going concern for 12 months from the date these condensed consolidated financial statements are issued.”
View the 10-Q filed Aug 6, 2026
Market Cap
$671.09M
Shares
181.38M

Price & Indicators

Indicators
Price
Panels
Event markers
20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$3.70 Open$3.83 Day$3.65–3.86 52W close$2.70–6.67 Avg vol 30d2.6M Short int35.0M · 19.3% float · 13.8d Short vol47% Last earningsNov 12, 2025 DataOct 2022–Sep 2026 Filing10-Q · Aug 6

Up next

Latest filing: 10-Q
filed Aug 6, 2026

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$4.63M
Trailing 12 months
Net income (TTM)
−$187.89M
Trailing 12 months
Revenue growth YoY
-61.6%
Year over year
Operating margin
-4,498.1%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
-23.4%
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$47.45M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+37.2%
Year over year · more shares
Price change (1Y)
+8.8%
Trailing year
Short interest
19.3%
Latest settlement · 13.8 days to cover
View all 114 metrics

Equibles Rating

blended score · not investment advice
Overall
Neutral
SellHoldBuy
Technical Buy Momentum Strong Sentiment Neutral Fundamentals Strong Quant / Vol Very High
Market backdrop VIX 14.5 · calm Equity put/call 0.58
Technical
price trend
Buy
50 / 200-day cross No cross
Price vs 200-day avg +4%
above
Price vs 50-day avg +9%
above
RSI (14) 59
neutral
MACD trend Positive
52-week position 25%
mid-range
Momentum
relative strength
Strong
1-month return +20%
trailing
6-month return +1%
trailing
YTD return +7%
this year
Relative strength −14%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $3 › 200d $4 — 200d above 50d
Institutional flow Distributing
-2% holders QoQ · +23 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
19.31% of float · ▲ +0.1% MoM · 13.8 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
189 holders — near 3-yr high, broad support
Squeeze score 77
high risk · 0–100
Fundamentals
Strong
Revenue growth +55%
Y/Y
EPS growth +18%
Y/Y
Free cash flow $-167.1M
Quant / Vol
risk profile
Very High
Volatility 89%
annualized · 1-yr
Max drawdown −60%
past year
ATR 6.5%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Technicals

trend & momentum for long-term holders Buy
0 · 3 · 3
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+4% Bullish
Price vs 50-day avg
+9% Bullish
RSI (14)
59 Neutral
MACD trend
Positive Bullish
52-week position
25% Neutral
Market signals — smart money & positioning
Bearish · 2 of 6
Trend (MA cross) No cross
50d $3 › 200d $4 — 200d above 50d
Institutional flow Distributing
-2% holders QoQ · +23 funds added
Insider flow Flat
No net insider activity over 90 days
Short interest Rising
19.31% of float · ▲ +0.1% MoM · 13.8 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
189 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $3 Now $4 · 25% Range high $7
vs 200-day avg +4% vs 50-day avg +9%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

Earlier KPI extraction records exist, but do not meet the current evidence-completeness requirements. No current verified series is available. Earlier figures remain withheld until revalidated; this is not evidence that the company reports no KPIs.

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
PRME
Prime Medicine, Inc.
this stock
$671.09M +6.6% +55.3% — 19.3%
VRTX
Vertex Pharmaceuticals Inc / Ma
 $141.42B +20.5% +46.2% 32.5 1.6%
REGN
Regeneron Pharmaceuticals, Inc.
 $85.22B +7.2% +20.8% 20.5 2.3%
ARGX
Argenx SE
 $64.44B +22.9% — — 1.9%
CSLLY
Csl Ltd
 $60.55B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
189
% held
59.4%
Net QoQ
+8.2M sh
Top holder
Alphabet Inc.
Held Float
View
Held by Funds
Fund positions
158
View
Short & Settlement
Short Interest Rising
Shares short
35.0M
Days to cover
13.8d
Change
+18.7K sh
View
Short Volume
Short vol %
47%
As of
Sep 4, 2026
Short Total
View
Fails to Deliver
FTD shares
68.3K
Value
$216.6K
As of
Aug 14, 2026
View
Off-Exchange
Off-exchange %
42.7%
Week of
Jul 27, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$4.6M
Net income (FY)
$-201.1M
EPS diluted
$-1.35
View
Filings
SEC Filings
Latest
8-K
Filed
Aug 6, 2026
This year
13
View
Proposed Sales
Value
$7.8M
Shares
522.6K
Filed
Jun 20, 2023
View
Earnings & Events
Earnings Calls
Last call
Jun 10, 2026
View

Performance

5D 20D 120D MTD YTD
PRME +2.5% +20.1% +0.8% +3.1% +6.6%
SPY +0.1% -0.4% +15.1% +0.4% +12.9%
vs SPY +2.4% +20.5% -14.3% +2.7% -6.3%
Key facts CIK 1894562 CUSIP 74168J101 13F (30d) 138 filings 138 filers Visit website Investor relations