PRME · Prime Medicine, Inc. · Holdings
$3.07
+0.09 (+3.02%)
At close · Oct 5
Return incl. dividend (before tax)
Going-concern doubt
— flagged Aug 6, 2026
Substantial doubt about the company's ability to continue as a going concern.
“As a result, we concluded that substantial doubt exists about our ability to continue as a going concern for 12 months from the date these condensed consolidated financial statements are issued.”View the 10-Q filed Aug 6, 2026
Market Cap
$525.99M
Shares
181.38M
Volume · Oct 5
1.23M
Avg daily vol (3M)
3.19M
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Some SEC filings for this period have not finished importing. Holder totals and changes may be incomplete; these filings remain queued for recovery.
Holders: 188
Total Value: $397,749,782
Total Shares: 107,791,302
Showing 1–100
of 193 holdings by value
· page 1 of 2
Institutional Ownership Trend
15 quarters
Holder Concentration
Across 188 13F filers · Δ vs Mar 31, 2026Top Holder
15.4%
−1.2 pts
Top 5
43.9%
+0.7 pts
Top 10
60.7%
−0.3 pts
HHI
556
Broadly held−19
Quarterly Activity
vs Mar 31, 2026
New
22
Increased
64
Decreased
68
Sold Out
27
Unchanged
34
Holder count:
-5
Institutional value:
+14.5%
Shares held:
+8.0%
Top Buyers
vs Mar 31, 2026| Institution | Added | Now Holds | Open |
|---|---|---|---|
| Mega GOLDMAN SACHS GROUP INC | +2,460,093 | 3,430,518 | |
| Large ARK Investment Management LLC | +2,101,919 | 8,348,746 | |
| Mega CITADEL ADVISORS LLC | +1,755,385 | 2,353,443 | |
| Mega STATE STREET CORP | +1,231,335 | 7,576,460 | |
| Mega BlackRock, Inc. | +1,100,333 | 9,602,041 |
Top Sellers
vs Mar 31, 2026| Institution | Sold | Now Holds | Open |
|---|---|---|---|
| Mega D. E. Shaw & Co., Inc. | −744,681 | 648,940 | |
| Large RENAISSANCE TECHNOLOGIES LLC | −623,627 | 117,412 | |
| Mid Amova Asset Management Americas, Inc. | −533,775 | 2,407,018 | |
| Mega Sumitomo Mitsui Trust Group, Inc. | −527,809 | 2,412,984 | |
| Large HRT FINANCIAL LP | −451,259 | 161,510 |
Top New Positions
vs Mar 31, 2026| Institution | Acquired | Value (USD) | Open |
|---|---|---|---|
| Large Jump Financial, LLC | 1,240,429 | $4,577,182 | |
| Large Point72 Asset Management, L.P. | 533,553 | $1,968,810 | |
| Mega MILLENNIUM MANAGEMENT LLC | 427,097 | $1,575,987 | |
| Large Jain Global LLC | 215,218 | $794,154 | |
| Large JUPITER ASSET MANAGEMENT LTD | 209,490 | $773,018 |
Top Sold-Out Positions
vs Mar 31, 2026| Institution | Previously Held | Last Value (USD) | Open |
|---|---|---|---|
| Small Elevate Capital Advisors, LLC | 151,069 | $525,720 | |
| Large TUDOR INVESTMENT CORP ET AL | 61,546 | $214,180 | |
| Mega JANUS HENDERSON GROUP PLC | 60,900 | $211,932 | |
| Mid Aquatic Capital Management LLC | 54,230 | $188,720 | |
| Small VARCOV Co. | 41,964 | $146,034 |
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Large Alphabet Inc. | $61,115,617 | 15.37% | 16,562,498 | Shares | 2026-08-07 | |
| Mega BlackRock, Inc. | $35,431,526 | 8.91% | 9,602,041 | Shares | 2026-08-07 | |
| Large ARK Investment Management LLC | $30,806,872 | 7.75% | 8,348,746 | Shares | 2026-08-14 | |
| Mega STATE STREET CORP | $27,957,137 | 7.03% | 7,576,460 | Shares | 2026-09-22 | |
| Mega T. Rowe Price Investment Management, Inc. | $19,325,755 | 4.86% | 5,237,332 | Shares | 2026-08-14 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC | $16,688,541 | 4.20% | 4,522,640 | Shares | 2026-08-13 | |
| Large Balyasny Asset Management L.P. | $14,645,912 | 3.68% | 3,969,082 | Shares | 2026-08-14 | |
| Mega GOLDMAN SACHS GROUP INC | $12,658,609 | 3.18% | 3,430,518 | Shares | 2026-08-14 | |
| Mid Casdin Capital, LLC | $11,686,875 | 2.94% | 3,167,175 | Shares | 2026-08-14 | |
| Large Woodline Partners LP | $11,084,405 | 2.79% | 3,003,904 | Shares | 2026-08-14 | |
| Mega UBS Group AG | $10,312,400 | 2.59% | 2,794,689 | Shares | 2026-08-13 | |
| Mega GEODE CAPITAL MANAGEMENT, LLC | $10,008,925 | 2.52% | 2,712,446 | Shares | 2026-08-12 | |
| Mega Sumitomo Mitsui Trust Group, Inc. | $8,903,910 | 2.24% | 2,412,984 | Shares | 2026-07-30 | |
| Mid Amova Asset Management Americas, Inc. | $8,881,896 | 2.23% | 2,407,018 | Shares | 2026-08-13 | |
| Mega CITADEL ADVISORS LLC | $7,581,263 | 1.91% | 2,054,543 | Shares | 2026-09-02 | |
| Mid ADAR1 Capital Management, LLC | $7,370,966 | 1.85% | 1,997,552 | Shares | 2026-08-14 | |
| Mega FMR LLC | $6,501,350 | 1.63% | 1,761,884 | Shares | 2026-08-13 | |
| Mega TWO SIGMA INVESTMENTS, LP | $5,625,445 | 1.41% | 1,524,511 | Shares | 2026-08-14 | |
| Mid Redmile Group, LLC | $5,127,742 | 1.29% | 1,389,632 | Shares | 2026-08-14 | |
| Large FARALLON CAPITAL MANAGEMENT LLC | $4,578,710 | 1.15% | 1,240,843 | Shares | 2026-08-14 | |
| Large Jump Financial, LLC | $4,577,182 | 1.15% | 1,240,429 | Shares | 2026-08-13 | |
| Mega BANK OF AMERICA CORP /DE/ Bank | $3,621,125 | 0.91% | 981,335 | Shares | 2026-08-14 | |
| Mega VANGUARD PORTFOLIO MANAGEMENT LLC | $3,549,137 | 0.89% | 961,826 | Shares | 2026-08-13 | |
| Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3,422,615 | 0.86% | 927,538 | Shares | 2026-08-14 | |
| Mega NORTHERN TRUST CORP Bank | $3,367,481 | 0.85% | 912,597 | Shares | 2026-08-13 | |
| Mega JPMORGAN CHASE & CO | $2,989,248 | 0.75% | 810,095 | Shares | 2026-08-12 | |
| Mid Greenwich Wealth Management LLC | $2,833,923 | 0.71% | 768,001 | Shares | 2026-08-12 | |
| Mega VANGUARD FIDUCIARY TRUST CO Bank | $2,821,495 | 0.71% | 764,633 | Shares | 2026-08-13 | |
| Mega MORGAN STANLEY | $2,616,068 | 0.66% | 708,963 | Shares | 2026-08-13 | |
| Small Alessandra Capital Management, LLC | $2,459,765 | 0.62% | 666,603 | Shares | 2026-07-28 | |
| Mega D. E. Shaw & Co., Inc. | $2,394,588 | 0.60% | 648,940 | Shares | 2026-08-14 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,392,887 | 0.60% | 648,479 | Shares | 2026-08-14 | |
| Large Point72 Asset Management, L.P. | $1,968,810 | 0.49% | 533,553 | Shares | 2026-08-14 | |
| Mid MOORE CAPITAL MANAGEMENT, LP | $1,845,000 | 0.46% | 500,000 | Shares | 2026-08-14 | |
| Small CHELSEA COUNSEL CO | $1,657,031 | 0.42% | 449,060 | Shares | 2026-08-12 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $1,635,039 | 0.41% | 443,100 | Put | 2026-08-14 | |
| Mega MILLENNIUM MANAGEMENT LLC | $1,575,987 | 0.40% | 427,097 | Shares | 2026-08-14 | |
| Mega HighTower Advisors, LLC | $1,255,946 | 0.32% | 340,365 | Shares | 2026-08-05 | |
| Mega DIMENSIONAL FUND ADVISORS LP | $1,124,260 | 0.28% | 304,678 | Shares | 2026-08-11 | |
| Mega WELLINGTON MANAGEMENT GROUP LLP | $1,123,397 | 0.28% | 304,444 | Shares | 2026-08-14 | |
| Mega Nuveen, LLC | $1,018,185 | 0.26% | 275,931 | Shares | 2026-08-11 | |
| Mega WELLS FARGO & COMPANY/MN | $928,945 | 0.23% | 251,747 | Shares | 2026-08-14 | |
| Mega Bank of New York Mellon Corp Bank | $909,007 | 0.23% | 246,344 | Shares | 2026-08-06 | |
| Mid IQ EQ FUND MANAGEMENT (IRELAND) Ltd | $833,198 | 0.21% | 225,799 | Shares | 2026-07-31 | |
| Mega MARSHALL WACE, LLP | $800,143 | 0.20% | 216,841 | Shares | 2026-08-13 | |
| Mid XTX Topco Ltd | $795,962 | 0.20% | 215,708 | Shares | 2026-08-14 | |
| Large Jain Global LLC | $794,154 | 0.20% | 215,218 | Shares | 2026-08-14 | |
| Large JUPITER ASSET MANAGEMENT LTD | $773,018 | 0.19% | 209,490 | Shares | 2026-08-10 | |
| Mega Swiss National Bank Bank | $768,627 | 0.19% | 208,300 | Shares | 2026-08-11 | |
| Large PEAK6 LLC | $767,730 | 0.19% | 208,057 | Shares | 2026-08-13 | |
| Mega CITIGROUP INC | $721,999 | 0.18% | 195,664 | Shares | 2026-08-03 | |
| Mega JANE STREET GROUP, LLC | $718,074 | 0.18% | 194,600 | Call | 2026-08-14 | |
| Small Green Alpha Advisors, LLC | $682,734 | 0.17% | 185,023 | Shares | 2026-08-11 | |
| Mid Keystone Financial Group | $614,421 | 0.15% | 166,510 | Shares | 2026-07-29 | |
| Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Mutual Fund | $599,026 | 0.15% | 162,338 | Shares | 2026-08-14 | |
| Mega PRICE T ROWE ASSOCIATES INC /MD/ | $598,979 | 0.15% | 162,325 | Shares | 2026-08-14 | |
| Large HRT FINANCIAL LP | $595,971 | 0.15% | 161,510 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC | $591,138 | 0.15% | 160,200 | Call | 2026-09-02 | |
| Mega CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension | $579,510 | 0.15% | 157,049 | Shares | 2026-08-24 | |
| Mid Bollard Group LLC | $557,691 | 0.14% | 151,136 | Shares | 2026-08-12 | |
| Mega ALLIANCEBERNSTEIN L.P. | $554,607 | 0.14% | 150,300 | Shares | 2026-08-14 | |
| Large Rafferty Asset Management, LLC | $536,064 | 0.13% | 145,275 | Shares | 2026-08-14 | |
| Mega Invesco Ltd. | $517,735 | 0.13% | 140,308 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC | $511,803 | 0.13% | 138,700 | Put | 2026-09-02 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $495,198 | 0.12% | 134,200 | Call | 2026-08-14 | |
| Large Concurrent Investment Advisors, LLC | $486,053 | 0.12% | 131,722 | Shares | 2026-07-27 | |
| Large ExodusPoint Capital Management, LP | $437,132 | 0.11% | 118,464 | Shares | 2026-08-14 | |
| Mega AQR CAPITAL MANAGEMENT LLC | $435,408 | 0.11% | 117,998 | Shares | 2026-08-14 | |
| Small Virtus Investment Advisers, LLC | $435,084 | 0.11% | 117,909 | Shares | 2026-08-11 | |
| Large RENAISSANCE TECHNOLOGIES LLC | $433,250 | 0.11% | 117,412 | Shares | 2026-08-13 | |
| Mega RHUMBLINE ADVISERS | $430,822 | 0.11% | 116,754 | Shares | 2026-08-12 | |
| Mega FIL Ltd | $425,110 | 0.11% | 115,206 | Shares | 2026-08-13 | |
| Mega DEUTSCHE BANK AG\ Bank | $422,400 | 0.11% | 114,472 | Shares | 2026-08-07 | |
| Large Steward Partners Investment Advisory, LLC | $399,590 | 0.10% | 108,290 | Shares | 2026-08-13 | |
| Small Palumbo Wealth Management LLC | $383,025 | 0.10% | 103,801 | Shares | 2026-08-12 | |
| Small MILESTONE ASSET MANAGEMENT, LLC | $369,129 | 0.09% | 100,035 | Shares | 2026-07-15 | |
| Mega TD Asset Management Inc | $347,406 | 0.09% | 94,148 | Shares | 2026-08-04 | |
| Mega LPL Financial LLC | $340,122 | 0.09% | 92,174 | Shares | 2026-08-07 | |
| Large Rockefeller Capital Management L.P. | $334,810 | 0.08% | 90,735 | Shares | 2026-08-13 | |
| Mega BARCLAYS PLC | $324,933 | 0.08% | 88,058 | Shares | 2026-08-14 | |
| Large Squarepoint Ops LLC | $324,827 | 0.08% | 88,029 | Shares | 2026-08-14 | |
| Large COMMONWEALTH EQUITY SERVICES, LLC | $322,173 | 0.08% | 87,310 | Shares | 2026-07-29 | |
| Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $314,757 | 0.08% | 85,300 | Shares | 2026-08-13 | |
| Large LOS ANGELES CAPITAL MANAGEMENT LLC | $303,705 | 0.08% | 82,305 | Shares | 2026-08-13 | |
| Mega JANE STREET GROUP, LLC | $285,606 | 0.07% | 77,400 | Put | 2026-08-14 | |
| Mid PROFUND ADVISORS LLC | $267,982 | 0.07% | 72,624 | Shares | 2026-08-11 | |
| Mega Legal & General Group Plc | $245,177 | 0.06% | 66,444 | Shares | 2026-08-14 | |
| Mega BNP PARIBAS ARBITRAGE, SA | $243,912 | 0.06% | 66,101 | Shares | 2026-08-13 | |
| Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC | $239,112 | 0.06% | 64,800 | Shares | 2026-08-14 | |
| Mega Jupiter Topco LLC | $224,721 | 0.06% | 60,900 | Shares | 2026-08-14 | |
| Mid Engineers Gate Manager LP | $218,200 | 0.05% | 59,133 | Shares | 2026-08-14 | |
| Mega VANGUARD ASSET MANAGEMENT, Ltd | $217,787 | 0.05% | 59,021 | Shares | 2026-08-13 | |
| Mega SG Americas Securities, LLC Broker-Dealer | $217,422 | 0.05% | 58,922 | Shares | 2026-08-07 | |
| Large &PARTNERS | $212,027 | 0.05% | 57,460 | Shares | 2026-08-14 | |
| Large MetLife Investment Management, LLC | $207,348 | 0.05% | 56,192 | Shares | 2026-08-14 | |
| Mega Russell Investments Group, Ltd. | $188,167 | 0.05% | 50,994 | Shares | 2026-08-06 | |
| Mega AMERIPRISE FINANCIAL INC | $184,282 | 0.05% | 49,941 | Shares | 2026-08-14 | |
| Mid Mutual Advisors, LLC | $166,050 | 0.04% | 45,000 | Shares | 2026-08-14 | |
| Mega Vanguard Global Advisers, LLC | $163,352 | 0.04% | 44,269 | Shares | 2026-08-13 | |
| Large Quadrature Capital Ltd | $161,116 | 0.04% | 43,663 | Shares | 2026-08-07 |