Skip to main content
Equibles

PRME

Prime Medicine, Inc.

Company with tickers: PRME

CIK
1894562
CUSIP
74168J101
Shares Outstanding
180,617,451
13F Activity (30d)
135 filings 130 filers

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Holders: 192
Total Value: $346,591,823
Total Shares: 99,595,386
Showing 1–100 of 197 holdings by value · page 1 of 2

Institutional Ownership Trend

14 quarters

Holder Concentration

Across 192 13F filers · Δ vs Dec 31, 2025
Top Holder
16.6%
Jun 2023 → Mar 2026 · range 16.6% – 25.7%
−0.2 pts
Top 5
43.3%
Jun 2023 → Mar 2026 · range 43.3% – 56.5%
−0.1 pts
Top 10
61.1%
Jun 2023 → Mar 2026 · range 61.1% – 80.2%
−0.4 pts
HHI
576
Jun 2023 → Mar 2026 · range 576 – 1,030
Broadly held −10

Quarterly Activity

vs Dec 31, 2025
New
39
Increased
74
Decreased
49
Sold Out
32
Unchanged
30
Holder count: +7
Institutional value: +1.5%
Shares held: +1.2%

Top Buyers

vs Dec 31, 2025
Institution Added Now Holds Open
Mega STATE STREET CORP +1,249,615 6,345,125
Large Balyasny Asset Management L.P. +999,003 4,123,365
Large ARK Investment Management LLC +878,301 6,246,827
Mega UBS Group AG +447,835 2,888,418
Mega JPMORGAN CHASE & CO +408,444 844,154

Top Sellers

vs Dec 31, 2025
Institution Sold Now Holds Open
Mega GOLDMAN SACHS GROUP INC −785,343 970,425
Mega MORGAN STANLEY −530,441 639,457
Mega T. Rowe Price Investment Management, Inc. −513,290 5,481,893
Large RENAISSANCE TECHNOLOGIES LLC −408,120 741,039
Mega FMR LLC −407,170 1,769,476

Top New Positions

vs Dec 31, 2025
Institution Acquired Value (USD) Open
Mega VANGUARD CAPITAL MANAGEMENT LLC 4,474,162 $15,570,083
Mid ADAR1 Capital Management, LLC 1,973,282 $6,867,021
Mid Redmile Group, LLC 1,590,832 $5,536,095
Mega VANGUARD PORTFOLIO MANAGEMENT LLC 862,204 $3,000,469
Mega VANGUARD FIDUCIARY TRUST CO 717,002 $2,495,166

Top Sold-Out Positions

vs Dec 31, 2025
Institution Previously Held Last Value (USD) Open
Mega VANGUARD GROUP INC 6,467,872 $22,443,513
Micro MWG Caph Ltd 1,792,210 $6,218,968
Large Point72 Asset Management, L.P. 551,030 $1,912,074
Large TWO SIGMA ADVISERS, LP 383,500 $1,330,745
Large Verition Fund Management LLC 290,983 $1,009,711
Filter: New 39 Increased 74 Reduced 49 Sold out 32 Unchanged 30
Showing 100 of 197
All Common Calls Puts
Export CSV
Holder Value (USD) % of 13F Shares Open
Mid Alphabet Inc. $57,637,493 16.63% 16,562,498
Mega BlackRock, Inc. $29,585,938 8.54% 8,501,708
Mega STATE STREET CORP $22,081,035 6.37% 6,345,125
Large ARK Investment Management LLC $21,738,957 6.27% 6,246,827
Mega T. Rowe Price Investment Management, Inc. $19,076,987 5.50% 5,481,893
Mega VANGUARD CAPITAL MANAGEMENT LLC $15,570,083 4.49% 4,474,162
Large Balyasny Asset Management L.P. $14,349,310 4.14% 4,123,365
Mid Casdin Capital, LLC $11,021,769 3.18% 3,167,175
Large Woodline Partners LP $10,451,529 3.02% 3,003,313
Mega Sumitomo Mitsui Trust Group, Inc. $10,233,959 2.95% 2,940,793
Mid Amova Asset Management Americas, Inc. $10,233,959 2.95% 2,940,793
Mega UBS Group AG $10,051,693 2.90% 2,888,418
Mega GEODE CAPITAL MANAGEMENT, LLC $9,548,075 2.75% 2,743,700
Mid ADAR1 Capital Management, LLC $6,867,021 1.98% 1,973,282
Mega FMR LLC $6,157,775 1.78% 1,769,476
Mid Redmile Group, LLC $5,536,095 1.60% 1,590,832
Mega TWO SIGMA INVESTMENTS, LP $5,473,382 1.58% 1,572,811
Mega D. E. Shaw & Co., Inc. $4,849,800 1.40% 1,393,621
Large FARALLON CAPITAL MANAGEMENT LLC $4,318,133 1.25% 1,240,843
Mega GOLDMAN SACHS GROUP INC $3,377,077 0.97% 970,425
Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC $3,191,897 0.92% 917,212
Mega NORTHERN TRUST CORP Bank $3,085,770 0.89% 886,716
Mega VANGUARD PORTFOLIO MANAGEMENT LLC $3,000,469 0.87% 862,204
Mega JPMORGAN CHASE & CO $2,937,653 0.85% 844,154
Mid Greenwich Wealth Management LLC $2,610,003 0.75% 750,001
Large RENAISSANCE TECHNOLOGIES LLC $2,578,815 0.74% 741,039
Mega VANGUARD FIDUCIARY TRUST CO Bank $2,495,166 0.72% 717,002
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $2,491,084 0.72% 715,829
Mega MORGAN STANLEY $2,225,307 0.64% 639,457
Large HRT FINANCIAL LP $2,132,436 0.62% 612,769
Mega BANK OF AMERICA CORP /DE/ Bank $2,007,973 0.58% 577,004
Mega AQR CAPITAL MANAGEMENT LLC $1,931,170 0.56% 554,935
Mid MOORE CAPITAL MANAGEMENT, LP $1,740,000 0.50% 500,000
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $1,555,560 0.45% 447,000
Small Alessandra Capital Management, LLC $1,480,774 0.43% 425,510
Mid Bollard Group LLC $1,256,753 0.36% 361,136
Large HighTower Advisors, LLC $1,184,087 0.34% 340,255
Mega CITADEL ADVISORS LLC $1,170,525 0.34% 336,358
Mega WELLS FARGO & COMPANY/MN $1,112,033 0.32% 319,550
Mega DIMENSIONAL FUND ADVISORS LP $1,059,735 0.31% 304,522
Mega WELLINGTON MANAGEMENT GROUP LLP $967,857 0.28% 278,120
Mega Nuveen, LLC $960,239 0.28% 275,931
Mega Bank of New York Mellon Corp Bank $929,920 0.27% 267,219
Small CHELSEA COUNSEL CO $789,960 0.23% 227,000
Mega JANE STREET GROUP, LLC $763,164 0.22% 219,300
Large Rafferty Asset Management, LLC $750,225 0.22% 215,582
Mid IQ EQ FUND MANAGEMENT (IRELAND) Ltd $714,753 0.21% 205,389
Small Green Alpha Advisors, LLC $665,275 0.19% 191,171
Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP $650,760 0.19% 187,000
Mega Swiss National Bank Bank $621,528 0.18% 178,600
Small Keystone Financial Group $577,714 0.17% 166,010
Mega CITADEL ADVISORS LLC $561,324 0.16% 161,300
Mega DEUTSCHE BANK AG\ Bank $547,891 0.16% 157,440
Mid XTX Topco Ltd $547,341 0.16% 157,282
Small Elevate Capital Advisors, LLC $525,720 0.15% 151,069
Mega JANE STREET GROUP, LLC $522,696 0.15% 150,200
Large MARSHALL WACE, LLP $494,010 0.14% 141,957
Mid BRIDGEWAY CAPITAL MANAGEMENT, LLC $469,104 0.14% 134,800
Mega PRICE T ROWE ASSOCIATES INC /MD/ $465,467 0.13% 133,755
Large MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. Mutual Fund $426,170 0.12% 122,463
Mega ALLIANCEBERNSTEIN L.P. $426,160 0.12% 122,460
Large Steward Partners Investment Advisory, LLC $408,746 0.12% 117,456
Mega FIL Ltd $400,916 0.12% 115,206
Mega RHUMBLINE ADVISERS $397,656 0.11% 114,269
Mid Engineers Gate Manager LP $384,011 0.11% 110,348
Small Palumbo Wealth Management LLC $355,816 0.10% 102,246
Mega CITADEL ADVISORS LLC $349,392 0.10% 100,400
Mega Invesco Ltd. $337,123 0.10% 96,875
Mid PROFUND ADVISORS LLC $333,404 0.10% 95,806
Mega TD Asset Management Inc $327,635 0.09% 94,148
Large Squarepoint Ops LLC $327,349 0.09% 94,066
Large Rockefeller Capital Management L.P. $318,073 0.09% 91,401
Large CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension $300,926 0.09% 86,473
Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC $296,844 0.09% 85,300
Large Mariner, LLC $272,825 0.08% 78,398
Mid Concurrent Investment Advisors, LLC $258,135 0.07% 74,177
Large IEQ CAPITAL, LLC $257,565 0.07% 74,013
Small Virtus Investment Advisers, LLC $231,447 0.07% 66,508
Mega Legal & General Group Plc $231,223 0.07% 66,444
Mega LPL Financial LLC $231,155 0.07% 66,424
Large Russell Investments Group, Ltd. $223,667 0.06% 64,273
Mega BARCLAYS PLC $221,929 0.06% 63,773
Large TUDOR INVESTMENT CORP ET AL $214,180 0.06% 61,546
Mega JANUS HENDERSON GROUP PLC $211,932 0.06% 60,900
Large &PARTNERS $206,955 0.06% 59,470
Mega VANGUARD ASSET MANAGEMENT, Ltd $205,393 0.06% 59,021
Mid Aquatic Capital Management LLC $188,720 0.05% 54,230
Large LOS ANGELES CAPITAL MANAGEMENT LLC $183,100 0.05% 52,615
Mega AMERIPRISE FINANCIAL INC $172,552 0.05% 49,584
Mega CITIGROUP INC $164,366 0.05% 47,232
Mid Quadrature Capital Ltd $163,187 0.05% 46,893
Mid Mutual Advisors, LLC $157,296 0.05% 45,200
Mega Vanguard Global Advisers, LLC $154,056 0.04% 44,269
Large MetLife Investment Management, LLC $153,843 0.04% 44,208
Small VARCOV Co. $146,034 0.04% 41,964
Small IvyRock Asset Management (HK) Ltd $145,464 0.04% 41,800
Large Corient Private Wealth LLC $143,449 0.04% 41,221
Mid DRW Securities, LLC Broker-Dealer $142,554 0.04% 40,964
Large JONES FINANCIAL COMPANIES LLLP $140,268 0.04% 40,307
Large WEALTH ENHANCEMENT ADVISORY SERVICES, LLC $131,129 0.04% 37,681

Report a Problem

Category
Description
Email (optional, for follow-up)