PRME · Prime Medicine, Inc. · Shareholders & Ownership

$4.02 +0.19 (+4.83%)

Russell 2000 member Rebalance outlook locked

Market Cap

$694.67M

181.38M

Volume · Oct 20 2.65M Avg daily vol (3M) 3.48M

Every disclosed holder of PRME in one list: 13F institutions, Schedule 13D and 13G filers, insiders (Forms 3, 4 and 5) and registered funds, each from its own latest filing. Holders nest by CIK and SEC reporting links, never by name, and each is summed once.

How the holder list picks a filing →

Who Owns PRME

13F quarter Sep 30, 2026, combined view: filers that have not filed yet carry their Jun 30, 2026 positions

Holder group	Holders	Shares	% Out	Summed
Institutional (13F)	183	106,624,163	58.79%	Yes
Insiders (Forms 3, 4, 5)	8	36,021,059	19.86%	Yes
13D/G-only blocks	3	33,674,340	18.57%	Yes
Remaining	—	5,057,294	2.79%	Rest
Registered funds (N-PORT, not summed)	153	35,624,192	19.64%	No

Shares outstanding: 181,376,856, the issuer's latest cover-page count restated onto today's split basis.

13D/G-only counts each filer's latest 13D or 13G that no 13F report of the listing contains, that names no 13F filer and that no counted insider files. Funds are never summed: their shares sit inside their advisers' 13F reports.

Holders of PRME

One row per holder Every filing By ultimate parent

All 13F Funds Insiders 13D/G Non-US

#	Holder	Shares	% Out	Change	As of	Notes
1	Liu David R. Insider CIK 1664439 · Jun 30, 2025 10% Owner, issuer-wide	20,240,945	11.16%	+21,000	Jun 30, 2025	10% Owner, issuer-wide
2	ARCH Venture Fund XII, L.P. 13D CIK 1906837 · Unknown · Aug 7, 2025 not summed	18,486,894	10.19%	+3,014,220	Aug 7, 2025	not summed
3	Alphabet Holdings LLC 13G CIK 1845041 · Unknown · Sep 30, 2025 Rule 13d-1(c), passive investor	16,562,498	9.13%	—	Sep 30, 2025	Rule 13d-1(c), passive investor
4	Alphabet Inc. 13F CIK 1652044 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	16,562,498	9.13%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
5	BRISTOL MYERS SQUIBB CO 13G CIK 14272 · Unknown · Sep 30, 2023 Rule 13d-1(c), passive investor	11,006,163	6.07%	—	Sep 30, 2023	Rule 13d-1(c), passive investor
6	BlackRock, Inc. 13F CIK 2012383 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	9,602,041	5.29%	+1,100,333	Jun 30, 2026	carried, not yet filed for the newest quarter
6.1	iShares Russell 2000 ETF Fund S000004344 · Registered fund · Jun 30, 2026 iShares Trust, not summed	2,509,092	1.38%	-25,493	Jun 30, 2026	iShares Trust, not summed
6.2	iShares Russell 2000 Growth ETF Fund S000004343 · Registered fund · Jun 30, 2026 iShares Trust, not summed	723,775	0.40%	—	Jun 30, 2026	iShares Trust, not summed
6.3	iShares Biotechnology ETF Fund S000004350 · Registered fund · Jun 30, 2026 iShares Trust, not summed	670,021	0.37%	-34,071	Jun 30, 2026	iShares Trust, not summed
6.4	iShares Micro-Cap ETF Fund S000004439 · Registered fund · Jun 30, 2026 iShares Trust, not summed	312,342	0.17%	+53,402	Jun 30, 2026	iShares Trust, not summed
6.5	iShares Core S&P Total U.S. Stock Market ETF Fund S000004317 · Registered fund · Jun 30, 2026 iShares Trust, not summed	197,241	0.11%	+4,624	Jun 30, 2026	iShares Trust, not summed
7	ARK Investment Management LLC 13F CIK 1697748 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	8,348,746	4.60%	+2,101,919	Jun 30, 2026	carried, not yet filed for the newest quarter
7.1	ARK Genomic Revolution ETF Fund S000042975 · Registered fund · Jul 31, 2026 ARK ETF Trust, not summed	7,513,485	4.14%	+2,587,621	Jul 31, 2026	ARK ETF Trust, not summed
8	STATE STREET CORP 13F CIK 93751 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	7,576,460	4.18%	+1,231,335	Jun 30, 2026	carried, not yet filed for the newest quarter
8.1	State Street(R) SPDR(R) S&P(R) Biotech ETF Fund S000010018 · Registered fund · Jun 30, 2026 SPDR SERIES TRUST, not summed	5,226,317	2.88%	+1,246,324	Jun 30, 2026	SPDR SERIES TRUST, not summed
8.2	STATE STREET SMALL/MID CAP EQUITY INDEX PORTFOLIO Fund S000050332 · Registered fund · Jun 30, 2026 STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed	37,100	0.02%	0	Jun 30, 2026	STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
8.3	State Street(R) SPDR(R) Portfolio MSCI Global Stock Market ETF Fund S000036082 · Registered fund · Jun 30, 2026 SPDR INDEX SHARES FUNDS, not summed	3,002	0.00%	+357	Jun 30, 2026	SPDR INDEX SHARES FUNDS, not summed
8.4	State Street Total Return V.I.S. Fund Fund S000001637 · Registered fund · Jun 30, 2026 STATE STREET VARIABLE INSURANCE SERIES FUNDS INC, not summed	2,212	0.00%	0	Jun 30, 2026	STATE STREET VARIABLE INSURANCE SERIES FUNDS INC, not summed
8.5	State Street Balanced Index Fund Fund S000082802 · Registered fund · Jun 30, 2026 STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed	645	0.00%	0	Jun 30, 2026	STATE STREET INSTITUTIONAL INVESTMENT TRUST, not summed
9	ARCH Venture Partners X, LLC Insider CIK 1769012 · Aug 1, 2025 10% Owner, issuer-wide	6,128,297	3.38%	—	Aug 1, 2025	10% Owner, issuer-wide
10	ARCH Venture Partners XII, LLC Insider CIK 1979548 · Aug 1, 2025 10% Owner, issuer-wide	6,128,297	3.38%	—	Aug 1, 2025	10% Owner, issuer-wide
11	Newpath Partners, L.P. 13G CIK 1755973 · Unknown · Dec 31, 2024 Rule 13d-1(d), exempt investor	6,105,679	3.37%	—	Dec 31, 2024	Rule 13d-1(d), exempt investor
12	T. Rowe Price Investment Management, Inc. 13F CIK 1897612 · Investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	5,237,332	2.89%	-244,561	Jun 30, 2026	carried, not yet filed for the newest quarter
13	VANGUARD CAPITAL MANAGEMENT LLC 13F CIK 2100119 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	4,522,640	2.49%	+48,478	Jun 30, 2026	carried, not yet filed for the newest quarter
14	Balyasny Asset Management L.P. 13F CIK 1218710 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	3,969,082	2.19%	-154,283	Jun 30, 2026	carried, not yet filed for the newest quarter
15	GOLDMAN SACHS GROUP INC 13F CIK 886982 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	3,430,518	1.89%	+2,460,093	Jun 30, 2026	carried, not yet filed for the newest quarter
15.1	Goldman Sachs Small Cap Value Insights Fund Fund S000014929 · Registered fund · Jul 31, 2026 Goldman Sachs Trust, not summed	126,214	0.07%	+2,512	Jul 31, 2026	Goldman Sachs Trust, not summed
15.2	Goldman Sachs Small Cap Equity Insights Fund Fund S000009329 · Registered fund · Jul 31, 2026 Goldman Sachs Trust, not summed	111,297	0.06%	-58,540	Jul 31, 2026	Goldman Sachs Trust, not summed
15.3	Goldman Sachs Small Cap Growth Insights Fund Fund S000014930 · Registered fund · Jul 31, 2026 Goldman Sachs Trust, not summed	51,258	0.03%	+23,115	Jul 31, 2026	Goldman Sachs Trust, not summed
15.4	Goldman Sachs Variable Insurance Trust Small Cap Equity Insights Fund Fund S000009355 · Registered fund · Jun 30, 2026 Goldman Sachs Variable Insurance Trust, not summed	28,891	0.02%	+5,639	Jun 30, 2026	Goldman Sachs Variable Insurance Trust, not summed
15.5	Goldman Sachs Innovate Equity ETF Fund S000068597 · Registered fund · May 31, 2026 Goldman Sachs ETF Trust, not summed	27,883	0.02%	+1,104	May 31, 2026	Goldman Sachs ETF Trust, not summed
16	GV 2021 GP, L.L.C. Insider CIK 1861206 · Aug 1, 2025 10% Owner, issuer-wide	3,262,440	1.80%	—	Aug 1, 2025	10% Owner, issuer-wide
17	Casdin Capital, LLC 13F CIK 1534261 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	3,167,175	1.75%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
18	VANGUARD TOTAL STOCK MARKET INDEX FUND Fund S000002848 · Registered fund · Jun 30, 2026 VANGUARD INDEX FUNDS, not summed	3,120,450	1.72%	0	Jun 30, 2026	VANGUARD INDEX FUNDS, not summed
19	Woodline Partners LP 13F CIK 1784547 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	3,003,904	1.66%	+591	Jun 30, 2026	carried, not yet filed for the newest quarter
20	ARK Venture Fund Fund · Registered fund · Jul 31, 2026 ARK Venture Fund, not summed	2,935,354	1.62%	—	Jul 31, 2026	ARK Venture Fund, not summed
21	UBS Group AG 13F CIK 1610520 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	2,794,689	1.54%	-93,729	Jun 30, 2026	carried, not yet filed for the newest quarter
22	GEODE CAPITAL MANAGEMENT, LLC 13F CIK 1214717 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	2,712,446	1.50%	-31,254	Jun 30, 2026	carried, not yet filed for the newest quarter
23	Sumitomo Mitsui Trust Group, Inc. 13F CIK 1475365 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	2,412,984	1.33%	-527,809	Jun 30, 2026	carried, not yet filed for the newest quarter
24	Amova Asset Management Americas, Inc. 13F CIK 1480751 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	2,407,018	1.33%	-533,775	Jun 30, 2026	carried, not yet filed for the newest quarter
25	CITADEL ADVISORS LLC 13F CIK 1423053 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	2,054,543	1.13%	+1,718,185	Jun 30, 2026	carried, not yet filed for the newest quarter
26	ADAR1 Capital Management, LLC 13F CIK 1940272 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,997,552	1.10%	+24,270	Jun 30, 2026	carried, not yet filed for the newest quarter
27	FMR LLC 13F CIK 315066 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	1,761,884	0.97%	-7,592	Jun 30, 2026	carried, not yet filed for the newest quarter
27.1	Fidelity Small Cap Index Fund Fund S000033638 · Registered fund · Jul 31, 2026 Fidelity Salem Street Trust, not summed	1,023,465	0.56%	+8,545	Jul 31, 2026	Fidelity Salem Street Trust, not summed
27.2	Fidelity Extended Market Index Fund Fund S000006021 · Registered fund · May 31, 2026 Fidelity Concord Street Trust, not summed	569,953	0.31%	-9,163	May 31, 2026	Fidelity Concord Street Trust, not summed
27.3	Fidelity Total Market Index Fund Fund S000006026 · Registered fund · May 31, 2026 Fidelity Concord Street Trust, not summed	230,949	0.13%	0	May 31, 2026	Fidelity Concord Street Trust, not summed
27.4	Fidelity Series Total Market Index Fund Fund S000065248 · Registered fund · May 31, 2026 Fidelity Concord Street Trust, not summed	167,791	0.09%	-21,074	May 31, 2026	Fidelity Concord Street Trust, not summed
27.5	Fidelity Nasdaq Composite Index Fund Fund S000055366 · Registered fund · May 31, 2026 Fidelity Concord Street Trust, not summed	113,377	0.06%	0	May 31, 2026	Fidelity Concord Street Trust, not summed
28	TWO SIGMA INVESTMENTS, LP 13F CIK 1179392 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,524,511	0.84%	-48,300	Jun 30, 2026	carried, not yet filed for the newest quarter
29	Redmile Group, LLC 13F CIK 1425738 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,389,632	0.77%	-201,200	Jun 30, 2026	carried, not yet filed for the newest quarter
30	VANGUARD EXTENDED MARKET INDEX FUND Fund S000002841 · Registered fund · Jun 30, 2026 VANGUARD INDEX FUNDS, not summed	1,300,373	0.72%	+49,774	Jun 30, 2026	VANGUARD INDEX FUNDS, not summed
31	FARALLON CAPITAL MANAGEMENT LLC 13F CIK 909661 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	1,240,843	0.68%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
32	Jump Financial, LLC 13F CIK 1831577 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	1,240,429	0.68%	+1,240,429	Jun 30, 2026	carried, not yet filed for the newest quarter
33	BANK OF AMERICA CORP /DE/ 13F CIK 70858 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	981,335	0.54%	+404,331	Jun 30, 2026	carried, not yet filed for the newest quarter
34	VANGUARD PORTFOLIO MANAGEMENT LLC 13F CIK 2100121 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	961,826	0.53%	+99,622	Jun 30, 2026	carried, not yet filed for the newest quarter
35	CHARLES SCHWAB INVESTMENT MANAGEMENT INC 13F CIK 884546 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	927,538	0.51%	+10,326	Jun 30, 2026	carried, not yet filed for the newest quarter
35.1	Schwab U.S. Small-Cap ETF Fund S000026636 · Registered fund · May 31, 2026 SCHWAB STRATEGIC TRUST, not summed	520,855	0.29%	-8,284	May 31, 2026	SCHWAB STRATEGIC TRUST, not summed
35.2	Schwab Small-Cap Index Fund Fund S000005912 · Registered fund · Jul 31, 2026 SCHWAB CAPITAL TRUST, not summed	239,900	0.13%	+19,222	Jul 31, 2026	SCHWAB CAPITAL TRUST, not summed
35.3	Schwab U.S. Broad Market ETF Fund S000026631 · Registered fund · May 31, 2026 SCHWAB STRATEGIC TRUST, not summed	89,719	0.05%	+1,437	May 31, 2026	SCHWAB STRATEGIC TRUST, not summed
35.4	Schwab Total Stock Market Index Fund Fund S000005913 · Registered fund · Jul 31, 2026 SCHWAB CAPITAL TRUST, not summed	77,214	0.04%	0	Jul 31, 2026	SCHWAB CAPITAL TRUST, not summed
36	NORTHERN TRUST CORP 13F CIK 73124 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	912,597	0.50%	+25,881	Jun 30, 2026	carried, not yet filed for the newest quarter
36.1	Small Cap Index Fund Fund S000001245 · Registered fund · Jun 30, 2026 Northern Funds, not summed	46,004	0.03%	-5,051	Jun 30, 2026	Northern Funds, not summed
36.2	Small Cap Core Fund Fund S000001244 · Registered fund · Jun 30, 2026 Northern Funds, not summed	11,401	0.01%	-542	Jun 30, 2026	Northern Funds, not summed
37	JPMORGAN CHASE & CO 13F CIK 19617 · Bank · Jun 30, 2026 carried, not yet filed for the newest quarter	810,095	0.45%	-34,059	Jun 30, 2026	carried, not yet filed for the newest quarter
38	Greenwich Wealth Management LLC 13F CIK 1439805 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	768,001	0.42%	+18,000	Jun 30, 2026	carried, not yet filed for the newest quarter
39	VANGUARD FIDUCIARY TRUST CO 13F CIK 933478 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	764,633	0.42%	+47,631	Jun 30, 2026	carried, not yet filed for the newest quarter
40	MORGAN STANLEY 13F CIK 895421 · Holding company · Jun 30, 2026 carried, not yet filed for the newest quarter	708,963	0.39%	+69,506	Jun 30, 2026	carried, not yet filed for the newest quarter
41	Alessandra Capital Management, LLC 13F CIK 2132506 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	666,603	0.37%	+241,093	Jun 30, 2026	carried, not yet filed for the newest quarter
42	D. E. Shaw & Co., Inc. 13F CIK 1009207 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	648,940	0.36%	-744,681	Jun 30, 2026	carried, not yet filed for the newest quarter
43	SUSQUEHANNA INTERNATIONAL GROUP, LLP 13F CIK 1446194 · Unknown · Jun 30, 2026 carried, not yet filed for the newest quarter	648,479	0.36%	-67,350	Jun 30, 2026	carried, not yet filed for the newest quarter
44	Point72 Asset Management, L.P. 13F CIK 1603466 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	533,553	0.29%	+533,553	Jun 30, 2026	carried, not yet filed for the newest quarter
45	VANGUARD RUSSELL 2000 INDEX FUND Fund S000030003 · Registered fund · May 31, 2026 VANGUARD SCOTTSDALE FUNDS, not summed	527,260	0.29%	+32,981	May 31, 2026	VANGUARD SCOTTSDALE FUNDS, not summed
46	MOORE CAPITAL MANAGEMENT, LP 13F CIK 1448574 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	500,000	0.28%	0	Jun 30, 2026	carried, not yet filed for the newest quarter
47	CHELSEA COUNSEL CO 13F CIK 1276755 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	449,060	0.25%	-13,280	Jun 30, 2026	carried, not yet filed for the newest quarter
48	MILLENNIUM MANAGEMENT LLC 13F CIK 1273087 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	427,097	0.24%	+427,097	Jun 30, 2026	carried, not yet filed for the newest quarter
49	HighTower Advisors, LLC 13F CIK 1462245 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	340,365	0.19%	+110	Jun 30, 2026	carried, not yet filed for the newest quarter
50	DIMENSIONAL FUND ADVISORS LP 13F CIK 354204 · Registered investment adviser · Jun 30, 2026 carried, not yet filed for the newest quarter	304,678	0.17%	+156	Jun 30, 2026	carried, not yet filed for the newest quarter
50.1	Dimensional U.S. Small Cap ETF Fund S000070906 · Registered fund · Jul 31, 2026 Dimensional ETF Trust, not summed	122,623	0.07%	0	Jul 31, 2026	Dimensional ETF Trust, not summed
50.2	U.S. SMALL CAP PORTFOLIO Fund S000000971 · Registered fund · Jul 31, 2026 DFA INVESTMENT DIMENSIONS GROUP INC, not summed	76,210	0.04%	+3,946	Jul 31, 2026	DFA INVESTMENT DIMENSIONS GROUP INC, not summed
50.3	Dimensional US Core Equity 1 ETF Fund S000081780 · Registered fund · Jul 31, 2026 Dimensional ETF Trust, not summed	13,330	0.01%	+10,187	Jul 31, 2026	Dimensional ETF Trust, not summed
50.4	U.S. MICRO CAP PORTFOLIO Fund S000000948 · Registered fund · Jul 31, 2026 DFA INVESTMENT DIMENSIONS GROUP INC, not summed	10,367	0.01%	+10,066	Jul 31, 2026	DFA INVESTMENT DIMENSIONS GROUP INC, not summed
50.5	Dimensional U.S. Core Equity 2 ETF Fund S000070903 · Registered fund · Jul 31, 2026 Dimensional ETF Trust, not summed	10,029	0.01%	0	Jul 31, 2026	Dimensional ETF Trust, not summed

19 more nested rows are not shown here; Every filing lists them all.

Shares are restated onto today's split basis. Change compares each row with the same holder's previous filing in the same source; a dash means there is none to compare. Nested 13D/G, insider and fund rows are not summed, since a 13F report already holds them.

Showing 1–50 of 255 holders

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Key facts CIK 1894562 CUSIP 74168J101 13F (30d) 12 filings 12 filers Visit website Investor relations