SEPN
Septerna, Inc.
$34.54
+0.18 (+0.52%)
At close · Jul 14
Market Cap
$1.54B
Shares
45,075,533
Price & Indicators
20d MA
50d MA
200d MA
Earnings
Filing
Insider
Congress
Investor day
Close$34.54
Open$34.27
Day$33.54–35.37
52W$10.62–38.04
Avg vol 30d513K
Short int3.2M · 7.0% float · 5.3d
Short vol35%
Last earningsMar 2, 2026
DataOct 2024–Jul 2026
Filing10-Q · May 11
Up next
FQ3-26 quarter ends
~Sep 30, 2026
Est
filed May 11, 2026
AI Brief
TL;DR.
Bullish
Bearish
From the call
AI-generated from the earnings call and 8-K · may contain errors · not investment advice
Equibles Rating
blended score · not investment advice
Overall
Buy
SellHoldBuy
Technical
Buy
Momentum
Strong
Sentiment
Bearish
Fundamentals
Excellent
Quant / Vol
Very High
Market backdrop
VIX 16.5 · calm
Equity put/call 0.62
Technical
price trend
50 / 200-day cross
No cross
Price vs 200-day avg
+31%
above
Price vs 50-day avg
+11%
above
RSI (14)
52
neutral
MACD trend
Negative
52-week position
87%
near high
Momentum
relative strength
1-month return
−4%
trailing
6-month return
+28%
trailing
YTD return
+24%
this year
Relative strength
+17%
vs S&P · 6-mo
Sentiment
smart money
Trend (MA cross)
No cross
50d $31 › 200d $26 — 50d above 200d
Institutional flow
Distributing
4 of 124 funds reported for Jun 30 · net -25.8K sh shares
Insider flow
Distributing
Net -$526.3K over 90 days · 100% sells
Short interest
Rising
7.00% of float · ▲ +18.3% MoM · 5.3 days cover
Volume signal
Normal
Volume near normal
Institution breadth
Multi-yr high
124 holders — near 1-yr high, broad support
Squeeze score
67
elevated · 0–100
Fundamentals
Revenue growth
+4175%
Y/Y
EPS growth
+85%
Y/Y
Free cash flow
$109.7M
Balance sheet
$120.7M
net cash
Quant / Vol
risk profile
Volatility
65%
annualized · 1-yr
Max drawdown
−25%
past year
ATR
6.7%
of price · 14-day
Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.
Technicals
trend & momentum for long-term holders Buy
50 / 200-day cross
No cross
Neutral
Price vs 200-day avg
+31%
Bullish
Price vs 50-day avg
+11%
Bullish
RSI (14)
52
Neutral
MACD trend
Negative
Bearish
52-week position
87%
Bullish
Market signals — smart money & positioning
Bearish · 3 of 6
Trend (MA cross)
No cross
50d $31 › 200d $26 — 50d above 200d
Institutional flow
Distributing
4 of 124 funds reported for Jun 30 · net -25.8K sh shares
Insider flow
Distributing
Net -$526.3K over 90 days · 100% sells
Short interest
Rising
7.00% of float · ▲ +18.3% MoM · 5.3 days cover
Volume signal
Normal
Volume near normal
Institution breadth
Multi-yr high
124 holders — near 1-yr high, broad support
Price context
position in its 52-week range
52-wk low $11
Now $35 · 87%
52-wk high $38
vs 200-day avg +31%
vs 50-day avg +11%
Illustrative technical + ownership context — a signal mix, not investment advice.
Versus peers
Biotechnology — same industry group| Company | Mkt cap | YTD | Rev growth Y/Y | P/E | Short % shares |
|---|---|---|---|---|---|
|
SEPN
this stock
Septerna, Inc.
|
$1.54B | +23.9% | +4174.5% | — | 7.0% |
|
ONC
BeOne Medicines Ltd.
|
$443.06B | +0.9% | +22179.2% | 901.7 | 0.1% |
|
VRTX
Vertex Pharmaceuticals Inc / Ma
|
$121.09B | +5.1% | +46.2% | 28.3 | 1.9% |
|
REGN
Regeneron Pharmaceuticals, Inc.
|
$69.66B | -14.9% | +20.8% | 16.2 | 3.3% |
|
ARGX
Argenx SE
|
$53.96B | +2.2% | — | — | 2.3% |
Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding
At a glance
key data from every sectionOwnership
Short & Settlement
Smart Money
Financials
Filings
Earnings & Events
Performance
| 5D | 20D | 120D | MTD | YTD | |
|---|---|---|---|---|---|
| SEPN | -3.6% | -3.9% | +27.8% | +3.1% | +23.9% |
| SPY | +0.6% | +1.4% | +11.0% | +0.7% | +10.3% |
| vs SPY | -4.2% | -5.3% | +16.8% | +2.5% | +13.6% |