SNTI · Senti Biosciences Holdings, Inc. · Holdings
Substantial doubt about the company's ability to continue as a going concern.
“We concluded that substantial doubt continued to exist and that our cash and cash equivalents of $6.5 million as of June 30, 2026, were not sufficient for us to continue as a going concern for at least one year from the issuance date of the condensed consolidated financial statements. Based on our current operating plan and existing unrestricted cash and cash equivalents, we have determined that we may not be able to maintain current operations starting as early as the fourth quarter of 2026. Additional funds will be necessary to maintain operations and to continue research and development activities. Our continued existence is dependent upon management's ability to raise capital, collect amounts owed to us under existing agreements and ultimately develop profitable operations. While management is devoting substantially all of its efforts to developing our business, raising capital and collecting amounts owed to us under existing agreements, there can be no assurance that our efforts will be successful.”View the 10-Q filed Aug 14, 2026
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Institutional Ownership Trend
Holder Concentration
Across 20 13F filersWho Holds SNTI
Last 8 quarters through Sep 30, 2026 (filing window open)Each kind of 13F filer's share of the common shares 13F filers report. Holder type comes from regulatory records, never the filer's name; style, turnover and horizon are measured from each filer's own 13F book. The quarter selector does not change this card.
Jun 30, 2026, the newest closed quarter: 20 filers, like-for-like change +2.7%; actively managed books +3.8%; index-like books -2.9%.
| Holder type | Share | Filers | Change |
|---|---|---|---|
| Registered adviser | 94.8% | 5 | +1.4% |
| Exempt adviser | 0.6% | 1 | 0.0% |
| Bank | 1.1% | 5 | +73.3% |
| Non-US | 0.0% | 1 | 0.0% |
| Holding company | 0.1% | 2 | -83.5% |
| Unknown | 3.4% | 6 | +60.1% |
| Style | Share | Filers | Change |
|---|---|---|---|
| Index-like | 14.9% | 7 | -2.9% |
| Systematic-like | 2.3% | 2 | +656.6% |
| Concentrated | 65.6% | 2 | +0.6% |
| Diversified active | 16.7% | 8 | +4.7% |
| Unknown | 0.6% | 1 | 0.0% |
| Not measured | 0.0% | 0 | — |
| Turnover | Share | Filers | Change |
|---|---|---|---|
| Low turnover | 69.3% | 8 | -0.8% |
| Medium turnover | 15.6% | 3 | +0.7% |
| High turnover | 3.7% | 6 | +564.3% |
| Unknown | 11.5% | 3 | 0.0% |
| Not measured | 0.0% | 0 | — |
| Holding horizon | Share | Filers | Change |
|---|---|---|---|
| Short horizon | 12.3% | 6 | +4.3% |
| Medium horizon | 0.1% | 2 | -82.9% |
| Long horizon | 72.3% | 11 | +4.0% |
| Unknown | 15.3% | 1 | -1.6% |
| Not measured | 0.0% | 0 | — |
| 13F book size | Share | Filers | Change |
|---|---|---|---|
| Under $1B | 0.6% | 2 | 0.0% |
| $1B to $10B | 81.4% | 6 | +0.8% |
| $100B or more | 18.0% | 12 | +16.1% |
| $10B to $100B | 0.0% | 0 | -100.0% |
| Not measured | 0.0% | 0 | — |
| Client base | Share | Filers | Change |
|---|---|---|---|
| Pooled investment vehicles | 82.3% | 3 | +2.3% |
| Registered funds and BDCs | 12.5% | 2 | -2.7% |
| Individuals and high net worth | 0.0% | 0 | -100.0% |
| Unknown | 5.2% | 15 | +35.9% |
| Private funds | Share | Filers | Change |
|---|---|---|---|
| Hedge funds | 17.2% | 2 | +12.1% |
| Venture capital funds | 65.8% | 2 | 0.0% |
| No private funds | 12.5% | 2 | -4.2% |
| Unknown | 4.5% | 14 | +42.9% |
| Location | Share | Filers | Change |
|---|---|---|---|
| United States | 99.3% | 14 | +2.4% |
| Outside the US | 0.7% | 6 | +64.4% |
The Sep 30, 2026 filing window is still open, so its bar carries the Jun 30, 2026 positions of filers that have not filed yet.
How the mix is measured
Shares are 13F common shares restated to today's split basis; options and principal amounts are left out. The change compares only filers with a 13F in both quarters and keeps each filer in its bucket of the later quarter on both sides; a filer that continues under a new CIK is compared through its successor. Holder type comes from each filer's current regulatory profile; client base and private funds come from the Form ADV roster current at each quarter end (rosters from December 2019, so an earlier quarter reads Unknown). Style, turnover, horizon and book size are measured from each filer's 13F book in the newest measured quarter, and Not measured means none was. Actively managed books are those measured systematic-like, concentrated or diversified active.
Conviction and Crowding
20 13F filers, quarter ended Jun 30, 2026Measured across every 13F filer's common-share book once the quarter's filing window closed. Crowding counts filers with high turnover or that advise private funds on Form ADV.
Managers in the top fifth by current three-year FundScore alpha were net buyers of $0 (0 buying, 0 selling).
Estimated Holder Cost Basis
Quarter ended Jun 30, 2026, on that quarter's share basisEstimated, never filed: each 13F buy is costed at its quarter's average traded price and each sale keeps the average cost, so this is what holders paid on average if they traded evenly through each quarter.
Estimated cost covers 20.1% of the 13F shares; positions already held when a filer's 13F history starts, or bought in a quarter without a trusted average price, have no estimate.
Shareholder Targets
13F filers that own its peers but not SNTI, quarter ended Jun 30, 2026SNTI has no holder-overlap peers, so these filers hold the largest Healthcare stocks: LLY, JNJ, ABBV, UNH, MRK, TMO, AMGN, AZN, GILD, ABT, ISRG, VRTX, CVS, DHR, SYK, BMY, PFE, MDT, MCK, ELV. 6,280 filers in all.
| # | Filer | In peers | Largest peers |
|---|---|---|---|
| 1 | VANGUARD PORTFOLIO MANAGEMENT LLC Registered adviser, Diversified active | $116,012,260,024 20 held | LLY, JNJ, ABBV |
| 2 | LILLY ENDOWMENT INC Unknown, Unknown | $108,400,867,760 1 held | LLY |
| 3 | FMR LLC Holding company, Diversified active | $102,008,860,554 20 held | LLY, UNH, GILD |
| 4 | JPMORGAN CHASE & CO Bank, Diversified active | $92,751,126,760 20 held | LLY, JNJ, ABBV |
| 5 | Capital World Investors Adviser, Diversified active | $89,827,396,720 14 held | LLY, VRTX, UNH |
| 6 | NORGES BANK Non-US, Index-like | $70,478,623,091 20 held | LLY, JNJ, ABBV |
| 7 | PRICE T ROWE ASSOCIATES INC /MD/ Registered adviser, Diversified active | $69,817,479,779 20 held | LLY, UNH, JNJ |
| 8 | PNC FINANCIAL SERVICES GROUP, INC. Bank, Concentrated | $67,493,367,200 20 held | LLY, JNJ, ABBV |
| 9 | Capital Research Global Investors Adviser, Diversified active | $66,678,636,531 16 held | LLY, VRTX, ABBV |
| 10 | WELLINGTON MANAGEMENT GROUP LLP Holding company, Diversified active | $62,277,671,744 20 held | LLY, MRK, JNJ |
Fund Ownership of SNTI by Fund Type
Registered funds' Form N-PORT reports for the quarter ended Jun 30, 2026Index funds and index ETFs hold 2.24% of shares outstanding.
| Fund type | Of shares outstanding | Shares |
|---|---|---|
| Index funds | 0.51% | 159,456 |
| Index ETFs | 1.73% | 537,504 |
| Active ETFs | 0.00% | 0 |
| Active funds | 0.00% | 0 |
| Unclassified | 0.00% | 0 |
| All registered funds | 2.24% | 696,960 |
How fund types are measured
Each fund series counts once, with its latest Form N-PORT report dated inside the quarter; only long share positions count, restated to today's split basis. The fund type is the series' latest Form N-CEN answer on or before the quarter end (the index-fund box and the exchange-traded flag), never its name. Unclassified funds have no usable N-CEN; unit investment trusts are among them, so index ownership is a floor. Funds sit inside their advisers' 13F reports, so these shares overlap the 13F figures and are never added to them.
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Mid NEA Management Company, LLC Registered adviser | $4,153,176 | 65.16% | 3,775,615 | Shares | 2026-08-14 | |
| Mid Nantahala Capital Management, LLC Registered adviser | $976,800 | 15.33% | 888,000 | Shares | 2026-08-19 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC Registered adviser | $591,254 | 9.28% | 537,504 | Shares | 2026-08-13 | |
| Mega GEODE CAPITAL MANAGEMENT, LLC Registered adviser | $205,771 | 3.23% | 187,065 | Shares | 2026-08-12 | |
| Mega CITADEL ADVISORS LLC Registered adviser | $117,810 | 1.85% | 107,100 | Shares | 2026-09-02 | |
| Mega VANGUARD FIDUCIARY TRUST CO | $100,312 | 1.57% | 91,193 | Shares | 2026-08-13 | |
| Mega JANE STREET GROUP, LLC | $57,782 | 0.91% | 52,530 | Shares | 2026-08-14 | |
| Small Menlo Ventures Management, L.P. Exempt adviser | $39,310 | 0.62% | 35,737 | Shares | 2026-08-10 | |
| Mega NORTHERN TRUST CORP Bank | $35,369 | 0.55% | 32,154 | Shares | 2026-08-13 | |
| Mid XTX Topco Ltd | $25,971 | 0.41% | 23,610 | Shares | 2026-08-14 | |
| Mid Virtu Financial LLC | $25,074 | 0.39% | 22,795 | Shares | 2026-08-13 | |
| Mega UBS Group AG Bank | $15,874 | 0.25% | 14,432 | Shares | 2026-08-13 | |
| Mega STATE STREET CORP Bank | $11,011 | 0.17% | 10,010 | Shares | 2026-09-22 | |
| Mid Tower Research Capital LLC (TRC) | $8,078 | 0.13% | 7,344 | Shares | 2026-08-11 | |
| Mega ROYAL BANK OF CANADA Bank | $4,416 | 0.07% | 4,015 | Shares | 2026-08-14 | |
| Mega BlackRock, Inc. Holding company | $4,404 | 0.07% | 4,004 | Shares | 2026-08-07 | |
| Mega BARCLAYS PLC Bank | $844 | 0.01% | 768 | Shares | 2026-08-14 | |
| Mega MORGAN STANLEY Holding company | $185 | 0.00% | 169 | Shares | 2026-08-13 | |
| Mid SBI Securities Co., Ltd. Non-US | $163 | 0.00% | 523 | Shares | 2026-10-22 | |
| Small Caitong International Asset Management Co., Ltd | $1 | 0.00% | 1 | Shares | 2026-08-05 |