ZYME · Zymeworks Inc.
Market Cap
$2.11B
Shares
70.96M
Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.
Holders: 204
Total Value: $1,793,723,727
Total Shares: 68,638,520
Showing 1–100
of 206 holdings by value
· page 1 of 3
Institutional Ownership Trend
16 quarters
Holder Concentration
Across 204 13F filers · Δ vs Mar 31, 2026Top Holder
33.5%
+1.0 pts
Top 5
61.3%
+2.3 pts
Top 10
72.9%
+1.9 pts
HHI
1,375
Broadly held+80
Quarterly Activity
vs Mar 31, 2026
New
25
Increased
61
Decreased
74
Sold Out
36
Unchanged
44
Holder count:
-11
Institutional value:
+1.2%
Shares held:
-3.0%
Top Buyers
vs Mar 31, 2026| Institution | Added | Now Holds | Open |
|---|---|---|---|
| Mid PERCEPTIVE ADVISORS LLC | +672,875 | 4,182,953 | |
| Large Assenagon Asset Management S.A. | +524,041 | 1,252,027 | |
| Mega Pictet Asset Management Holding SA | +298,931 | 308,187 | |
| Small Prosight Management, LP | +135,385 | 674,434 | |
| Large STATE OF WISCONSIN INVESTMENT BOARD | +89,473 | 155,579 |
Top Sellers
vs Mar 31, 2026| Institution | Sold | Now Holds | Open |
|---|---|---|---|
| Mega Nuveen, LLC | −532,273 | 119,389 | |
| Mega DEUTSCHE BANK AG\ | −524,060 | 397,190 | |
| Mid Capricorn Fund Managers Ltd | −520,681 | 486,529 | |
| Mega ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | −325,401 | 418,497 | |
| Mega BlackRock, Inc. | −302,858 | 4,251,030 |
Top New Positions
vs Mar 31, 2026| Institution | Acquired | Value (USD) | Open |
|---|---|---|---|
| Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | 889,802 | $23,259,424 | |
| Mega FIRST TRUST ADVISORS LP | 340,363 | $8,897,088 | |
| Mid Y-Intercept (Hong Kong) Ltd | 83,455 | $2,181,513 | |
| Large LMR Partners LLP | 82,500 | $2,156,550 | |
| Mega TWO SIGMA INVESTMENTS, LP | 71,874 | $1,878,786 |
Top Sold-Out Positions
vs Mar 31, 2026| Institution | Previously Held | Last Value (USD) | Open |
|---|---|---|---|
| Mid MPM BIOIMPACT LLC | 565,249 | $14,153,834 | |
| Large ROYCE & ASSOCIATES LP | 299,202 | $7,492,018 | |
| Large HRT FINANCIAL LP | 237,889 | $5,956,740 | |
| Mega AMERICAN CENTURY COMPANIES INC | 70,851 | $1,774,109 | |
| Small DLD Asset Management, LP | 53,000 | $1,327,120 |
| Holder | Value (USD) | % of 13F | Shares | Type | Filed | Open |
|---|---|---|---|---|---|---|
| Mid EcoR1 Capital, LLC | $600,445,942 | 33.47% | 22,970,388 | Shares | 2026-08-14 | |
| Large Rubric Capital Management LP | $182,980,000 | 10.20% | 7,000,000 | Shares | 2026-08-14 | |
| Mega BlackRock, Inc. | $111,121,917 | 6.20% | 4,251,030 | Shares | 2026-08-07 | |
| Mid PERCEPTIVE ADVISORS LLC | $109,342,391 | 6.10% | 4,182,953 | Shares | 2026-08-14 | |
| Mid BVF INC/IL | $95,388,571 | 5.32% | 3,649,142 | Shares | 2026-08-14 | |
| Mega MORGAN STANLEY | $58,325,133 | 3.25% | 2,231,260 | Shares | 2026-08-13 | |
| Large BNP PARIBAS ASSET MANAGEMENT Holding S.A. | $46,558,370 | 2.60% | 1,781,116 | Shares | 2026-08-13 | |
| Mega VANGUARD CAPITAL MANAGEMENT LLC | $40,752,207 | 2.27% | 1,558,998 | Shares | 2026-08-13 | |
| Large Assenagon Asset Management S.A. | $32,727,985 | 1.82% | 1,252,027 | Shares | 2026-08-21 | |
| Mid Nextech Invest, Ltd. | $29,118,548 | 1.62% | 1,113,946 | Shares | 2026-08-14 | |
| Mega STATE STREET CORP | $28,445,966 | 1.59% | 1,088,216 | Shares | 2026-08-07 | |
| Mega DIMENSIONAL FUND ADVISORS LP | $26,008,122 | 1.45% | 994,955 | Shares | 2026-08-11 | |
| Mega CITADEL ADVISORS LLC | $23,895,514 | 1.33% | 914,136 | Shares | 2026-09-02 | |
| Large NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | $23,259,424 | 1.30% | 889,802 | Shares | 2026-08-14 | |
| Mega FMR LLC | $18,365,126 | 1.02% | 702,568 | Shares | 2026-08-13 | |
| Mega GEODE CAPITAL MANAGEMENT, LLC | $18,099,596 | 1.01% | 692,410 | Shares | 2026-08-12 | |
| Small Prosight Management, LP | $17,629,704 | 0.98% | 674,434 | Shares | 2026-08-14 | |
| Mega Qube Research & Technologies Ltd | $15,516,442 | 0.87% | 593,590 | Shares | 2026-08-14 | |
| Mega VANGUARD PORTFOLIO MANAGEMENT LLC | $13,332,236 | 0.74% | 510,032 | Shares | 2026-08-13 | |
| Mid Redmile Group, LLC | $12,851,835 | 0.72% | 491,654 | Shares | 2026-08-14 | |
| Mid Capricorn Fund Managers Ltd | $12,717,868 | 0.71% | 486,529 | Shares | 2026-07-24 | |
| Mega GOLDMAN SACHS GROUP INC | $12,307,286 | 0.69% | 470,822 | Shares | 2026-08-14 | |
| Mega ARROWSTREET CAPITAL, LIMITED PARTNERSHIP | $10,939,511 | 0.61% | 418,497 | Shares | 2026-08-13 | |
| Mega DEUTSCHE BANK AG\ Bank | $10,382,545 | 0.58% | 397,190 | Shares | 2026-08-07 | |
| Mid Hillsdale Investment Management Inc. | $10,009,581 | 0.56% | 382,922 | Shares | 2026-08-12 | |
| Mega FIRST TRUST ADVISORS LP | $8,897,088 | 0.50% | 340,363 | Shares | 2026-08-11 | |
| Mid Granahan Investment Management, LLC | $8,787,143 | 0.49% | 336,157 | Shares | 2026-08-14 | |
| Mega NORTHERN TRUST CORP Bank | $8,392,846 | 0.47% | 321,073 | Shares | 2026-08-13 | |
| Mega Pictet Asset Management Holding SA | $8,056,008 | 0.45% | 308,187 | Shares | 2026-07-30 | |
| Large PICTON MAHONEY ASSET MANAGEMENT | $7,092,906 | 0.40% | 271,343 | Shares | 2026-08-13 | |
| Large SILVERCREST ASSET MANAGEMENT GROUP LLC | $5,849,243 | 0.33% | 223,766 | Shares | 2026-08-14 | |
| Mega BANK OF AMERICA CORP /DE/ Bank | $5,726,514 | 0.32% | 219,071 | Shares | 2026-08-14 | |
| Mega WELLS FARGO & COMPANY/MN | $5,677,581 | 0.32% | 217,199 | Shares | 2026-08-14 | |
| Mid SummitTX Capital, L.P. | $5,510,364 | 0.31% | 210,802 | Shares | 2026-08-14 | |
| Large Man Group plc | $5,509,763 | 0.31% | 210,779 | Shares | 2026-08-14 | |
| Large FEDERATED HERMES, INC. | $4,914,188 | 0.27% | 187,995 | Shares | 2026-08-12 | |
| Mega RAYMOND JAMES FINANCIAL INC | $4,350,113 | 0.24% | 166,416 | Shares | 2026-08-14 | |
| Large STATE OF WISCONSIN INVESTMENT BOARD | $4,066,835 | 0.23% | 155,579 | Shares | 2026-08-14 | |
| Mega CHARLES SCHWAB INVESTMENT MANAGEMENT INC | $3,984,154 | 0.22% | 152,416 | Shares | 2026-08-14 | |
| Mid KENNEDY CAPITAL MANAGEMENT LLC | $3,800,390 | 0.21% | 145,386 | Shares | 2026-08-14 | |
| Mega D. E. Shaw & Co., Inc. | $3,785,254 | 0.21% | 144,807 | Shares | 2026-08-14 | |
| Small DIADEMA PARTNERS LP | $3,715,330 | 0.21% | 142,132 | Shares | 2026-08-14 | |
| Mega CITIGROUP INC | $3,435,867 | 0.19% | 131,441 | Shares | 2026-08-03 | |
| Mega Bank of New York Mellon Corp Bank | $3,427,109 | 0.19% | 131,106 | Shares | 2026-08-06 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $3,408,656 | 0.19% | 130,400 | Call | 2026-08-14 | |
| Mid XTX Topco Ltd | $3,290,424 | 0.18% | 125,877 | Shares | 2026-08-14 | |
| Mega Nuveen, LLC | $3,120,827 | 0.17% | 119,389 | Shares | 2026-08-11 | |
| Large PANAGORA ASSET MANAGEMENT INC | $3,100,282 | 0.17% | 118,603 | Shares | 2026-08-06 | |
| Mega UBS Group AG | $3,008,581 | 0.17% | 115,095 | Shares | 2026-08-13 | |
| Mega Invesco Ltd. | $2,933,219 | 0.16% | 112,212 | Shares | 2026-08-14 | |
| Mega AQR CAPITAL MANAGEMENT LLC | $2,908,908 | 0.16% | 111,282 | Shares | 2026-08-14 | |
| Mega WELLINGTON MANAGEMENT GROUP LLP | $2,875,765 | 0.16% | 110,014 | Shares | 2026-08-14 | |
| Mega JPMORGAN CHASE & CO | $2,781,243 | 0.16% | 106,398 | Shares | 2026-08-12 | |
| Mid Tema ETFs LLC Mutual Fund | $2,760,776 | 0.15% | 105,615 | Shares | 2026-07-10 | |
| Large Tidal Investments LLC | $2,760,776 | 0.15% | 105,615 | Shares | 2026-08-13 | |
| Small PLATINUM INVESTMENT MANAGEMENT LTD | $2,749,509 | 0.15% | 105,184 | Shares | 2026-08-13 | |
| Small Manatuck Hill Partners, LLC | $2,614,000 | 0.15% | 100,000 | Shares | 2026-08-14 | |
| Mega SUSQUEHANNA INTERNATIONAL GROUP, LLP | $2,451,932 | 0.14% | 93,800 | Put | 2026-08-14 | |
| Mid KORNITZER CAPITAL MANAGEMENT INC /KS | $2,321,232 | 0.13% | 88,800 | Shares | 2026-07-31 | |
| Large MACKENZIE FINANCIAL CORP | $2,293,654 | 0.13% | 87,745 | Shares | 2026-08-13 | |
| Mega PRINCIPAL FINANCIAL GROUP INC | $2,221,637 | 0.12% | 84,990 | Shares | 2026-08-04 | |
| Mid Y-Intercept (Hong Kong) Ltd | $2,181,513 | 0.12% | 83,455 | Shares | 2026-07-14 | |
| Large LMR Partners LLP | $2,156,550 | 0.12% | 82,500 | Shares | 2026-08-14 | |
| Mega AMERIPRISE FINANCIAL INC | $2,150,380 | 0.12% | 82,264 | Shares | 2026-08-14 | |
| Mega UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | $2,126,722 | 0.12% | 81,359 | Shares | 2026-08-13 | |
| Mega VANGUARD FIDUCIARY TRUST CO Bank | $2,094,336 | 0.12% | 80,120 | Shares | 2026-08-13 | |
| Large STIFEL FINANCIAL CORP | $2,018,373 | 0.11% | 77,214 | Shares | 2026-08-12 | |
| Mega FRANKLIN RESOURCES INC | $2,000,440 | 0.11% | 76,528 | Shares | 2026-08-13 | |
| Mega RHUMBLINE ADVISERS | $1,962,225 | 0.11% | 75,066 | Shares | 2026-08-12 | |
| Mega Swiss National Bank Bank | $1,939,588 | 0.11% | 74,200 | Shares | 2026-08-11 | |
| Mid MARTINGALE ASSET MANAGEMENT L P | $1,915,591 | 0.11% | 73,282 | Shares | 2026-08-13 | |
| Mega TWO SIGMA INVESTMENTS, LP | $1,878,786 | 0.10% | 71,874 | Shares | 2026-08-14 | |
| Mid Dana Investment Advisors, Inc. | $1,873,192 | 0.10% | 71,660 | Shares | 2026-08-13 | |
| Large CREDIT AGRICOLE S A | $1,855,940 | 0.10% | 71,000 | Shares | 2026-08-14 | |
| Mega Fisher Asset Management, LLC | $1,850,058 | 0.10% | 70,775 | Shares | 2026-08-04 | |
| Mid SEGALL BRYANT & HAMILL, LLC | $1,747,093 | 0.10% | 66,836 | Shares | 2026-08-12 | |
| Small Verdad Advisers, LP | $1,743,224 | 0.10% | 66,688 | Shares | 2026-08-14 | |
| Mid Susquehanna Portfolio Strategies, LLC | $1,705,582 | 0.10% | 65,248 | Shares | 2026-08-14 | |
| Mid Campbell & CO Investment Adviser LLC | $1,591,246 | 0.09% | 60,874 | Shares | 2026-08-03 | |
| Mega ROYAL BANK OF CANADA Bank | $1,471,104 | 0.08% | 56,278 | Shares | 2026-08-14 | |
| Mega ALLIANCEBERNSTEIN L.P. | $1,461,121 | 0.08% | 55,896 | Shares | 2026-08-14 | |
| Mega CITADEL ADVISORS LLC | $1,364,508 | 0.08% | 52,200 | Call | 2026-09-02 | |
| Small Virtus Investment Advisers, LLC | $1,328,565 | 0.07% | 50,825 | Shares | 2026-08-11 | |
| Mega ENVESTNET ASSET MANAGEMENT INC | $1,272,364 | 0.07% | 48,675 | Shares | 2026-08-03 | |
| Mega Russell Investments Group, Ltd. | $1,251,240 | 0.07% | 47,867 | Shares | 2026-08-06 | |
| Large Quantinno Capital Management LP | $1,245,361 | 0.07% | 47,642 | Shares | 2026-08-13 | |
| Small North Growth Management Ltd. | $1,202,440 | 0.07% | 46,000 | Shares | 2026-07-22 | |
| Mega Legal & General Group Plc | $1,128,201 | 0.06% | 43,160 | Shares | 2026-08-14 | |
| Mega VICTORY CAPITAL MANAGEMENT INC | $1,111,577 | 0.06% | 42,524 | Shares | 2026-08-07 | |
| Large MARSHALL WACE, LLP | $1,070,380 | 0.06% | 40,948 | Shares | 2026-08-13 | |
| Large O'SHAUGHNESSY ASSET MANAGEMENT, LLC | $1,033,418 | 0.06% | 39,534 | Shares | 2026-08-13 | |
| Mega PRICE T ROWE ASSOCIATES INC /MD/ | $1,006,024 | 0.06% | 38,486 | Shares | 2026-08-14 | |
| Mega CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM Pension | $986,628 | 0.06% | 37,744 | Shares | 2026-08-24 | |
| Large JACOBS LEVY EQUITY MANAGEMENT, INC | $965,141 | 0.05% | 36,922 | Shares | 2026-08-14 | |
| Large TUDOR INVESTMENT CORP ET AL | $953,351 | 0.05% | 36,471 | Shares | 2026-08-14 | |
| Large HighTower Advisors, LLC | $943,654 | 0.05% | 36,100 | Shares | 2026-08-05 | |
| Small Persistent Asset Partners Ltd | $939,340 | 0.05% | 35,935 | Shares | 2026-08-07 | |
| Small HighVista Strategies LLC | $889,099 | 0.05% | 34,013 | Shares | 2026-08-14 | |
| Large COMMONWEALTH EQUITY SERVICES, LLC | $837,839 | 0.05% | 32,052 | Shares | 2026-07-29 | |
| Small SBI Okasan Asset Management Co.Ltd. | $836,480 | 0.05% | 32,000 | Shares | 2026-07-22 |
Key facts
CIK
1937653
CUSIP
98985Y108
13F (30d)
158 filings
157 filers
Visit website
Investor relations