6-K

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C.  20549

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER

PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE

SECURITIES EXCHANGE ACT OF 1934

August 20, 2025

Commission File Number: 001-32827

MACRO BANK INC.

(Translation of registrant’s name intoEnglish)

Av. Eduardo Madero 1182

Buenos Aires C1106ACY

Tel: 54 11 5222 6500

(Address of registrant’s principal executiveoffices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):

INDEX

Translation of a submission from Banco Macro to the CNV dated on August 20, 2025.

City of Buenos Aires, August 20^th^ 2025

To

Comisión Nacional de Valores (Argentine Securities Exchange Commission)

Please be advised that on the date hereof Mr. Lucas Matías Gregorio, who was formerly acting as Alternate Director, has taken office as Regular Director until the next general shareholders’ meeting, pursuant to the provisions of section 14 of the Bank’s bylaws, in lieu of Mr. Guido Agustín Gallino whose resignation has been accepted.

Sincerely,

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereto duly authorized.

Date: August 20, 2025