6-K

SECURITIES AND EXCHANGE COMMISSION

Washington**,D.C.  20549**

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER

PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE

SECURITIES EXCHANGE ACT OF 1934

July 14, 2021

Commission File Number: 001-32827

MACRO BANK INC.

(Translation of registrant’s name intoEnglish)

Av. Eduardo Madero 1182

Buenos Aires C1106ACY

Tel: 54 11 5222 6500

(Address of registrant’s principal executiveoffices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):

Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):

INDEX

Translation of a submission from Banco Macro to the CNV dated on July 14, 2021.

City of Buenos Aires, July 14 2021

To

Comisión Nacional de Valores (Argentine Securities Exchange Commission)

Re.         Relevant Event

Please be advised that last July 12^th^ Mr. Santiago Horacio Seeber has informed his resignation as Regular Director, further expressing that his decision to leave the Board is strictly based on personal reasons.

In addition, we inform that on the date hereof, Mr. Marcos Brito, who was formerly acting as Alternate Director, has taken office as Regular Director until the next general shareholders’ meeting, pursuant to the provisions of section 14 of the Bank’s bylaws.

Sincerely,

SIGNATURE

Pursuant to the requirements of the Securities Exchange Act of 1934, the Registrant has duly caused this report to be signed on its behalf by the undersigned, thereto duly authorized.

Date: July 14, 2021