IMNM 8-K
Immunome Inc. (IMNM)
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM
CURRENT REPORT
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Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Item 2.02 Results of Operations and Financial Condition.
On August 11, 2026, Immunome, Inc. (the “Company”) announced its financial results for the second quarter ended June 30, 2026 and provided a business update in the press release attached hereto as Exhibit 99.1 and incorporated herein by reference.
The information in this Item 2.02 of this Current Report on Form 8-K, including Exhibit 99.1, is furnished and shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, or subject to the liabilities of that section or Sections 11 and 12(a)(2) of the Securities Act of 1933, as amended. The information shall not be deemed incorporated by reference into any other filing with the Securities and Exchange Commission made by the Company, whether made before or after today’s date, regardless of any general incorporation language in such filing, except as shall be expressly set forth by specific references in such filing.
Item 9.01 Financial Statements and Exhibits.
(d)
Exhibit Number |
Description |
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99.1 |
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104 |
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Cover Page Interactive Data File (embedded within the Inline XBRL document). |
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
Date: August 11, 2026 |
Immunome, Inc. |
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By: |
/s/ Max Rosett |
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Name: |
Max Rosett |
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Title: |
Chief Financial Officer |
Exhibit 99.1
Immunome Reports Second Quarter 2026 Financial Results and Provides Business Update
August 11, 2026
BOTHELL, Wash. – Immunome, Inc. (Nasdaq: IMNM), a biotechnology company focused on developing first-in-class and best-in-class targeted cancer therapies, today announced financial results for the quarter ended June 30, 2026, and provided a business update.
“We continue to execute against our strategy of building a diversified targeted oncology company with multiple opportunities to bring needed therapies to patients,” said Clay B. Siegall, Ph.D., President and Chief Executive Officer of Immunome. “For varegacestat, the presentation of detailed Phase 3 RINGSIDE data at ASCO and subsequent FDA acceptance of our NDA with a PDUFA target action date of April 28, 2027 represent important steps toward a potential approval and launch. We are also continuing to advance our broader pipeline, with three additional clinical-stage programs now enrolling patients. We believe this momentum positions us well for a milestone-rich second half of 2026.”
Pipeline Highlights
Varegacestat:
IM-1021: The Phase 1 clinical trial of IM-1021 is ongoing, with objective responses observed in participants with B-cell lymphoma at multiple dose levels. Immunome expects to present initial lymphoma data for IM-1021 in 2026.
IM-1617: In June 2026, the first patient was dosed in the Phase 1, first-in-human trial evaluating IM-1617 in patients with advanced solid tumors. The study is designed to evaluate safety, tolerability, pharmacokinetics and preliminary anti-tumor activity and is expected to include participants with advanced solid tumors, including colorectal cancer, non-small cell lung cancer and breast cancer.
IM-3050: In July 2026, the first patient was dosed in the Phase 1, first-in-human trial evaluating IM-3050 in patients with FAP-expressing advanced solid tumors. The trial is designed to evaluate safety, tolerability, dosimetry, pharmacokinetics and preliminary anti-tumor activity of the investigational FAP-targeted radioligand therapy.
Preclinical ADC Pipeline: Immunome expects to submit Investigational New Drug applications (INDs) for IM-1340 and IM-1335 in mid- and late 2026, respectively. The programs are each directed at undisclosed solid tumor targets and incorporate HC74. Additional undisclosed ADCs are in discovery and lead optimization to support INDs in 2027 and beyond.
Second Quarter 2026 Financial Results
About Immunome, Inc.
Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets.
Cautionary Statement Regarding Forward-Looking Statements
Statements in this press release that are not purely historical in nature are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. We use words such as “planned,” “expected,” “focused,” “advance,” “projected,” “will,” “potential,” “expect,” “intend,” “plan,” “pursue,” “support,” “expects,” “advancing,” and similar expressions to identify these forward-looking statements. These forward-looking statements include statements regarding progress of Immunome’s pipeline and achievement of key milestones; the proposed timeline for expected data with respect to Immunome’s pipeline; Immunome’s plans and timing for submission of additional INDs; the design and anticipated scope of Immunome’s ongoing and planned clinical trials; the potential of Immunome’s pipeline of assets to be first-in-class and best-in-class; Immunome’s plans and timeline for initiating additional clinical trials; Immunome’s anticipated timing for submitting a Marketing Authorization Application to the European Medicines Agency for varegacestat; Immunome’s expected cash runway; and other statements regarding management’s intentions, plans, beliefs, expectations or forecasts for the future. These forward-looking statements are based on Immunome’s current expectations and involve assumptions that may never materialize or may prove to be incorrect; consequently, actual results may differ materially from those expressed or implied in the statements due to a number of factors, including the risk that regulatory approvals for Immunome’s programs and product candidates are not obtained, are delayed or are subject to unanticipated conditions; the risk that preclinical data may not be predictive of clinical data or that early clinical data may not be predictive of later clinical data, regulatory approval or commercial viability; the risk of reliance on third-party vendors; the risk that Immunome’s programs and product candidates fail to achieve their intended endpoints; the risk that Immunome will not be able to realize the benefits of its strategic transactions; uncertainties related to Immunome’s capital requirements and Immunome’s expected cash runway; Immunome’s ability to grow and advance its pipeline and successfully execute on its business plan; and other risks and uncertainties included under the caption “Risk Factors” in Immunome’s Quarterly Report on Form 10-Q for the quarter ended March 31, 2026, filed with the Securities and Exchange Commission (“SEC”) on May 12, 2026, and in Immunome’s Quarterly Report on Form 10-Q for the quarter ended June 30, 2026, to be filed with the SEC later today. These documents can also be accessed on Immunome’s website at www.immunome.com by clicking on the link “Financials” under the “Investors” tab. The forward-looking statements included in this press release are made only as of the date hereof. Except as required by law, Immunome assumes no obligation and does not intend to update any forward-looking statements included in this press release.
Investor Contact:
Max Rosett
Chief Financial Officer
IMMUNOME, INC.
Condensed Consolidated Balance Sheets
(In thousands)
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June 30, 2026 |
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December 31, 2025 |
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(unaudited) |
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Assets |
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Current assets: |
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Cash and cash equivalents |
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$ |
217,706 |
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$ |
653,482 |
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Marketable securities |
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302,290 |
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— |
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Prepaid expenses and other current assets |
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18,453 |
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7,295 |
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Total current assets |
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538,449 |
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660,777 |
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Property and equipment, net |
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17,359 |
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14,636 |
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Operating right-of-use assets |
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3,942 |
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2,978 |
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Restricted cash |
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210 |
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210 |
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Other long-term assets |
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5,424 |
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4,587 |
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Total assets |
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$ |
565,384 |
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$ |
683,188 |
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Liabilities and stockholders’ equity |
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Current liabilities: |
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Accounts payable |
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$ |
5,996 |
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$ |
3,339 |
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Accrued expenses and other current liabilities |
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29,717 |
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41,651 |
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Total current liabilities |
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35,713 |
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44,990 |
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Operating lease liabilities, net of current portion |
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4,588 |
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3,855 |
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Total liabilities |
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40,301 |
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48,845 |
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Stockholders’ equity: |
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Preferred stock |
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— |
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— |
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Common stock |
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11 |
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11 |
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Additional paid-in capital |
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1,380,535 |
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1,362,496 |
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Accumulated other comprehensive loss |
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(333) |
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— |
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Accumulated deficit |
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(855,130 |
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(728,164 |
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Total stockholders’ equity |
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525,083 |
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634,343 |
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Total liabilities and stockholders’ equity |
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$ |
565,384 |
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$ |
683,188 |
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IMMUNOME, INC.
Condensed Consolidated Statements of Operations and Comprehensive Loss
(In thousands, except share and per share amounts)
(unaudited)
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Three Months Ended June 30, |
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2026 |
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2025 |
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Collaboration revenue |
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$ |
— |
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$ |
4,015 |
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Operating expenses: |
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Research and development(1) |
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59,885 |
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40,451 |
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General and administrative(1) |
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18,250 |
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10,042 |
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Total operating expenses |
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78,135 |
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50,493 |
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Loss from operations |
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(78,135 |
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(46,478 |
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Interest income |
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5,008 |
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3,081 |
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Net loss |
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$ |
(73,127 |
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$ |
(43,397 |
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Net loss per share, basic and diluted |
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$ |
(0.65 |
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$ |
(0.50 |
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Weighted-average shares outstanding, basic and diluted |
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113,272,931 |
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87,010,742 |
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Comprehensive loss: |
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Net loss |
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$ |
(73,127 |
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$ |
(43,397 |
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Unrealized loss on marketable securities |
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(333) |
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(21) |
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Comprehensive loss |
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$ |
(73,460 |
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$ |
(43,418 |
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(1) Amounts include non-cash share-based compensation as follows (in thousands): |
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Three Months Ended June 30, |
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2026 |
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2025 |
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Research and development |
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$ |
4,161 |
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$ |
2,233 |
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General and administrative |
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4,638 |
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3,114 |
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Total share-based compensation expense |
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$ |
8,799 |
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$ |
5,347 |
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