6-K

UNITEDSTATES

SECURITIESAND EXCHANGE COMMISSION

WASHINGTON,D.C. 20549

FORM 6-K

REPORTOF FOREIGN PRIVATE ISSUER

PURSUANTTO RULE 13a-16 OR 15d-16 UNDER

THESECURITIES EXCHANGE ACT OF 1934

Forthe month of July 2025

CommissionFile Number: 001-38208

MetalphaTechnology Holding Limited

Suite6703-04, Central Plaza

18Harbour Road, Wan Chai,

HongKong, China

(Address of Principal Executive Offices)

Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.

Form 20-F  ☒     Form 40-F  ☐

INCORPORATIONBY REFERENCE

This current report on Form 6-K, including the Exhibit 99.1 attached hereto, shall be deemed to be incorporated by reference into the Metalpha Technology Holding Limited’s registration statements on Form S-8 (File No. 333-255251 and File No. 333-283335) and to be a part thereof from the date on which this current report is furnished, to the extent not superseded by documents or reports subsequently filed or furnished.

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EXHIBITINDEX

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SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: July 25, 2025

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Exhibit 99.1

Former Asia Head of Rothschild joins Digital-Asset Wealth Firm Metalpha

HONG KONG, July 25, 2025 /PRNewswire/ -- Metalpha Technology Holding Limited (Nasdaq: MATH) (“Metalpha” or the “Company”), a leading digital asset-focused wealth management company, today announced the appointment of Mrs. Monique Chan as CEO of LSQ Capital Limited (“LSQ Capital”)，the Company’s Hong Kong-based subsidiary licensed by the Securities and Futures Commission (SFC). She will be focus on building a digital asset friendly family office platform, effective on August 1, 2025.

Mrs. Chan brings over 30 years of banking experience, having held senior positions such as CEO of Banque Privée Edmond de Rothschild HK and Asia Head of the Rothschild Group, Chief Executive HK of HSBC Private Bank, CEO of BMO Private Bank Asia, and Vice Chair Asia of Bank J. Safra Sarasin. She also served on the board of Private Wealth Management Association and has been awarded the Top 50 Most Influential Private Banking Executives in Asia.

“Combining Mrs. Chan’s exceptional wealth management expertise with our innovative digital asset solutions, we are uniquely positioned to redefine the digital asset wealth management for ultra-high-net-worth (UHNW) clients and family offices.” said Mr. Adrian Wang, CEO of Metalpha.

About Metalpha

Metalpha Technology Holding Limited (Nasdaq: MATH), through its subsidiaries, is dedicated to providing digital asset-focused wealth management services with a full-service, institutional-grade platform. With dedicated blockchain expertise, the Company aims to become a leader in the field of digital asset-based wealth management services, bringing robust innovation and transparency to the customers and businesses it serves.

Forward-Looking Statements

This press release contains statements that may constitute “forward-looking” statements pursuant to the “safe harbor” provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by terminology such as “will,” “expects,” “anticipates,” “aims,” “future,” “intends,” “plans,” “believes,” “estimates,” “likely to” and similar statements. Management has based these forward-looking statements on its current expectations, assumptions, estimates and projections. While they believe these expectations, assumptions, estimates and projections are reasonable, such forward-looking statements are only predictions and involve known and unknown risks and uncertainties, many of which are beyond management’s control. These statements involve risks and uncertainties that may cause Metalpha’s actual results, performance or achievements to differ materially from any future results, performance or achievements expressed or implied by these forward-looking statements.