TWST · Twist Bioscience Corp

$136.40 -6.00 (-4.21%) At close · Aug 20

Market Cap

$8.55B

62.71M

Institutional ownership from SEC Form 13F filings. Investment managers with more than $100 million in U.S. equities must disclose their positions every quarter, within 45 days of quarter-end, so the holdings shown can lag the market by up to a quarter.

Quarter:

Holders: 336

Total Value: $7,902,023,482

Total Shares: 76,808,174

Institutional Ownership Trend

26 quarters

Superinvestors Holding TWST

All superinvestors →

Ray Dalio $1,918,403 Joel Greenblatt $326,026

Holder Concentration

Across 336 13F filers · Δ vs Mar 31, 2026

Top Holder

7.6%

−0.6 pts

Top 5

30.6%

−6.8 pts

Top 10

48.1%

−6.1 pts

HHI

309

Broadly held−79

Quarterly Activity

vs Mar 31, 2026

New

Increased

Decreased

100

Sold Out

Unchanged

Holder count: +54

Institutional value: +115.0%

Shares held: -0.7%

Top Buyers

vs Mar 31, 2026

Institution	Added	Now Holds
Mega PRICE T ROWE ASSOCIATES INC /MD/	+3,564,347	3,634,652
Mega FMR LLC	+2,813,099	4,703,044
Mega D. E. Shaw & Co., Inc.	+1,138,961	1,185,605
Large FARALLON CAPITAL MANAGEMENT LLC	+708,750	2,136,400
Large VOYA INVESTMENT MANAGEMENT LLC	+661,478	671,866

Top Sellers

vs Mar 31, 2026

Institution	Sold	Now Holds
Large WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC	−3,095,124	2,174,594
Large EdgePoint Investment Group Inc.	−2,860,886	2,521,635
Large ARK Investment Management LLC	−1,792,930	4,549,803
Large Artisan Partners Limited Partnership	−1,565,760	4,802,017
Mid Soleus Capital Management, L.P.	−1,122,000	104,629

Top New Positions

vs Mar 31, 2026

Institution	Acquired	Value (USD)
Mid Stephens Investment Management Group LLC	767,364	$78,946,408
Mega FIL Ltd	641,096	$65,955,956
Mega T. Rowe Price Investment Management, Inc.	597,935	$61,515,552
Large MARSHALL WACE, LLP	396,912	$40,834,306
Mid Granahan Investment Management, LLC	314,882	$32,395,060

Top Sold-Out Positions

vs Mar 31, 2026

Institution	Previously Held	Last Value (USD)
Large Point72 Asset Management, L.P.	669,732	$31,825,664
Large Holocene Advisors, LP	344,758	$16,382,900
Small Blue Water Life Science Advisors, LP	276,000	$13,115,520
Large Schonfeld Strategic Advisors LLC	258,604	$12,288,862
Mid Meridiem Capital Partners LP	239,669	$11,389,070

Filter: New 91 Increased 99 Reduced 100 Sold out 37 Unchanged 46

Showing 100 of 344

All Common Calls Puts

Compact Export CSV

Holder

Value (USD)

% of 13F

BlackRock, Inc.

$600,190,699

7.60%

5,833,891

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BLACKROCK FINANCIAL MANAGEMENT INC/DE	88,396	$9,094,180	1.5%	Sole
BlackRock Investment Management (Australia) Ltd	132	$13,580	0.0%	Sole
BlackRock Asset Management Canada Ltd	12,159	$1,250,917	0.2%	Sole
BlackRock Investment Management, LLC	184,731	$19,005,125	3.2%	Sole
BLACKROCK ADVISORS LLC	291,543	$29,993,943	5.0%	Sole
BlackRock Fund Advisors	2,965,539	$305,094,652	50.8%	Sole
BlackRock Institutional Trust Company, N.A.	1,971,982	$202,877,508	33.8%	Sole
BlackRock Japan Co. Ltd	1,656	$170,369	0.0%	Sole
BlackRock Fund Managers Ltd.	10,663	$1,097,009	0.2%	Sole
BlackRock Investment Management (UK) Ltd.	19,433	$1,999,267	0.3%	Sole
BlackRock Asset Management Ireland Ltd	177,138	$18,223,957	3.0%	Sole
BlackRock Life Ltd	260	$26,748	0.0%	Sole
BlackRock Asset Management Schweiz AG	10,363	$1,066,145	0.2%	Sole
Aperio Group, LLC	99,876	$10,275,242	1.7%	Sole
SpiderRock Advisors, LLC	20	$2,057	0.0%	Sole

Artisan Partners Limited Partnership

$494,031,508

6.25%

4,802,017

FMR LLC

$483,849,165

6.12%

4,703,044

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fidelity Management & Research Co LLC	4,606,994	$473,967,542	98.0%	Defined
STRATEGIC ADVISERS LLC	1,111	$114,299	0.0%	Defined
Fidelity Institutional Asset Management Trust Co	67,000	$6,892,960	1.4%	Defined
FIAM LLC	27,939	$2,874,364	0.6%	Defined

ARK Investment Management LLC

$468,083,732

5.92%

4,549,803

PRICE T ROWE ASSOCIATES INC /MD/

$373,932,997

4.73%

3,634,652

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
T. Rowe Price International Ltd	85,045	$8,749,429	2.3%	Defined
Held directly	3,549,607	$365,183,568	97.7%	Sole

STATE STREET CORP

$332,562,892

4.21%

3,232,532

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STATE STREET GLOBAL ADVISORS EUROPE LIMITED joint	3,232,532	$332,562,892	100.0%	Defined

VANGUARD PORTFOLIO MANAGEMENT LLC

$290,634,868

3.68%

2,824,989

VANGUARD CAPITAL MANAGEMENT LLC

$277,701,926

3.51%

2,699,280

EdgePoint Investment Group Inc.

$259,425,808

3.28%

2,521,635

WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC

$223,722,230

2.83%

2,174,594

FARALLON CAPITAL MANAGEMENT LLC

$219,792,832

2.78%

2,136,400

Invesco Ltd.

$198,376,197

2.51%

1,928,229

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Invesco Advisers, Inc. joint	1,808,158	$186,023,293	93.8%	Defined
Invesco Trust Co joint	24,750	$2,546,280	1.3%	Defined
Invesco Capital Management LLC	95,321	$9,806,624	4.9%	Defined

GEODE CAPITAL MANAGEMENT, LLC

$166,599,859

2.11%

1,619,361

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GEODE CAPITAL MANAGEMENT TRUST COMPANY, LLC	229,088	$23,568,573	14.1%	Defined
Held directly	1,390,273	$143,031,286	85.9%	Defined

Thrivent Financial for Lutherans

$147,478,787

1.87%

1,433,503

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Thrivent Asset Management, LLC	1,058,559	$108,904,549	73.8%	Defined
Held directly	374,944	$38,574,238	26.2%	Sole

GOLDMAN SACHS GROUP INC

$144,898,041

1.83%

1,408,418

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
GOLDMAN SACHS & CO. LLC	854,544	$87,915,486	60.7%	Defined
GOLDMAN SACHS ASSET MANAGEMENT, L.P.	537,186	$55,265,695	38.1%	Defined
Goldman Sachs Trust Company, N.A. joint	16,688	$1,716,860	1.2%	Defined

MORGAN STANLEY

$122,412,897

1.55%

1,189,861

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MORGAN STANLEY & CO INTERNATIONAL PLC	938	$96,501	0.1%	Defined
MORGAN STANLEY & CO. LLC	28,294	$2,910,886	2.4%	Defined
MORGAN STANLEY CAPITAL SERVICES, LLC	964,757	$99,254,200	81.1%	Defined
MORGAN STANLEY SMITH BARNEY LLC	6,166	$634,358	0.5%	Defined
Morgan Stanley Wealth Management Australia Pty Ltd	2,932	$301,644	0.2%	Defined
PARAMETRIC PORTFOLIO ASSOCIATES LLC	166,774	$17,157,708	14.0%	Defined
EATON VANCE MANAGEMENT	20,000	$2,057,600	1.7%	Defined

D. E. Shaw & Co., Inc.

$121,975,041

1.54%

1,185,605

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
D. E. SHAW & CO, L.P.	1,015,413	$104,465,689	85.6%	Defined
D. E. Shaw Investment Management, L.L.C. joint	170,192	$17,509,352	14.4%	Defined

BAILLIE GIFFORD & CO

$111,807,822

1.41%

1,086,779

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BAILLIE GIFFORD & CO LTD	288,847	$29,716,579	26.6%	Defined
BAILLIE GIFFORD OVERSEAS LTD	124,157	$12,773,272	11.4%	Defined
Baillie Gifford Investment Management (Europe) Ltd	169,110	$17,398,036	15.6%	Defined
Held directly	504,665	$51,919,935	46.4%	Sole

Driehaus Capital Management LLC

$105,197,474

1.33%

1,022,526

Sumitomo Mitsui Trust Group, Inc.

$102,915,390

1.30%

1,000,344

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Amova Asset Management Co., Ltd.	1,000,344	$102,915,390	100.0%	Defined

Amova Asset Management Americas, Inc.

$102,852,633

1.30%

999,734

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Sumitomo Mitsui Trust Group, Inc. joint	999,734	$102,852,633	100.0%	Sole

BANK OF AMERICA CORP /DE/

$94,921,922

1.20%

922,647

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BANK OF AMERICA NA	306,830	$31,566,670	33.3%	Defined
BOFA SECURITIES, INC.	535,806	$55,123,721	58.1%	Defined
MANAGED ACCOUNT ADVISORS LLC joint	80,011	$8,231,531	8.7%	Defined

CITADEL ADVISORS LLC

$88,686,880

1.12%

862,042

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	177,507	$18,261,920	20.6%	Defined
Held directly	684,535	$70,424,960	79.4%	Defined

LOOMIS SAYLES & CO L P

$88,611,468

1.12%

861,309

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
LOOMIS SAYLES TRUST COMPANY, LLC	192,492	$19,803,576	22.3%	Defined
Held directly	668,817	$68,807,892	77.7%	Defined

Stephens Investment Management Group LLC

$78,946,408

1.00%

767,364

First Light Asset Management, LLC

$74,889,747

0.95%

727,933

VOYA INVESTMENT MANAGEMENT LLC

$69,121,573

0.87%

671,866

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Voya Investment Management Co. LLC joint	671,866	$69,121,573	100.0%	Defined

FIL Ltd

$65,955,956

0.83%

641,096

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIL Investments International	641,096	$65,955,956	100.0%	Defined

T. Rowe Price Investment Management, Inc.

$61,515,552

0.78%

597,935

NORTHERN TRUST CORP

$60,872,860

0.77%

591,688

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NORTHERN TRUST CO joint	541,196	$55,678,244	91.5%	Defined
NORTHERN TRUST GLOBAL INVESTMENTS LTD	40,854	$4,203,059	6.9%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC joint	9,638	$991,557	1.6%	Other

DIMENSIONAL FUND ADVISORS LP

$59,948,380

0.76%

582,702

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Dimensional Fund Advisors Ltd.	3,589	$369,236	0.6%	Defined
DFA Australia Ltd.	7,601	$781,990	1.3%	Defined
Dimensional Ireland Ltd	11,612	$1,194,642	2.0%	Defined
Held directly	559,900	$57,602,512	96.1%	Sole

WELLINGTON MANAGEMENT GROUP LLP

$58,471,537

0.74%

568,347

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Wellington Management Company LLP	258,330	$26,576,990	45.5%	Defined
Wellington Managment Canada LLC	646	$66,460	0.1%	Defined
Wellington Management Singapore Pte. Ltd.	47,897	$4,927,643	8.4%	Defined
Wellington Management International Ltd	16,772	$1,725,503	3.0%	Defined
Wellington Trust Company, NA joint	243,222	$25,022,679	42.8%	Defined
Wellington Management Europe GmbH	1,480	$152,262	0.3%	Defined

UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC

$58,001,888

0.73%

563,782

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Group AG	1,332	$137,036	0.2%	Defined
UBS Asset Management Switzerland AG	189,000	$19,444,319	33.5%	Sole
UBS Asset Management (UK) Ltd.	7,220	$742,792	1.3%	Other
Held directly	366,230	$37,677,741	65.0%	Defined

FRED ALGER MANAGEMENT, LLC

$57,423,192

0.73%

558,157

CHARLES SCHWAB INVESTMENT MANAGEMENT INC

$57,317,637

0.73%

557,131

BNP PARIBAS ARBITRAGE, SA

$56,239,043

0.71%

546,647

Nuveen, LLC

$53,707,782

0.68%

522,043

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nuveen Asset Management, LLC joint	36,584	$3,763,761	7.0%	Defined
TIAA CREF INVESTMENT MANAGEMENT LLC joint	146,673	$15,089,718	28.1%	Defined
TEACHERS ADVISORS, LLC joint	338,786	$34,854,303	64.9%	Defined

AMERICAN CENTURY COMPANIES INC

$50,105,749

0.63%

487,031

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AMERICAN CENTURY INVESTMENT MANAGEMENT INC	487,031	$50,105,749	100.0%	Defined

Tao Capital Management LP

$49,260,487

0.62%

478,815

NEW YORK STATE COMMON RETIREMENT FUND

$47,545,477

0.60%

462,145

JENNISON ASSOCIATES LLC

$46,626,861

0.59%

453,216

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Prudential Financial Inc	353,920	$36,411,289	78.1%	Defined
Prudential Trust Company	99,296	$10,215,572	21.9%	Other

VANGUARD FIDUCIARY TRUST CO

$45,624,605

0.58%

443,474

Allspring Global Investments Holdings, LLC

$43,017,110

0.54%

418,129

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Allspring Funds Management, LLC reporting on behalf of Morgan Stanley Smith Barney, LLC	13,243	$1,362,439	3.2%	Other
Allspring Global Investments, LLC reporting on behalf of UBS ASSET MANAGEMENT AMERICAS INC	404,886	$41,654,671	96.8%	Defined

UBS Group AG

$42,502,504

0.54%

413,127

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
UBS Financial Services Inc	71,883	$7,395,323	17.4%	Defined
UBS AG	275,560	$28,349,612	66.7%	Defined
UBS Switzerland AG	65,423	$6,730,718	15.8%	Defined
UBS Securities LLC	261	$26,851	0.1%	Defined

MARSHALL WACE, LLP

$40,834,306

0.52%

396,912

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marshall Wace North America L.P. joint	396,912	$40,834,306	100.0%	Other

MILLENNIUM MANAGEMENT LLC

$35,714,586

0.45%

347,148

AMERIPRISE FINANCIAL INC

$34,986,606

0.44%

340,072

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Columbia Management Investment Advisers, LLC	320,914	$33,015,632	94.4%	Defined
Ameriprise Trust Co	19,101	$1,965,110	5.6%	Defined
Ameriprise Financial Services, LLC	57	$5,864	0.0%	Defined

Granahan Investment Management, LLC

$32,395,060

0.41%

314,882

LORD, ABBETT & CO. LLC

$30,787,457

0.39%

299,256

FEDERATED HERMES, INC.

$30,669,864

0.39%

298,113

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FEDERATED INVESTMENT COUNSELING	771	$79,320	0.3%	Defined
FEDERATED EQUITY MANAGEMENT CO OF PENNSYLVANIA	5,547	$570,675	1.9%	Defined
FEDERATED MDTA LLC	163,432	$16,813,884	54.8%	Defined
HERMES INVESTMENT MANAGEMENT LTD	128,363	$13,205,985	43.1%	Defined

SEI INVESTMENTS CO

$30,342,500

0.38%

294,931

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI INVESTMENTS MANAGEMENT CORP	521	$53,600	0.2%	Sole
SEI TRUST CO	294,410	$30,288,900	99.8%	Sole

BLAIR WILLIAM & CO/IL

$26,394,481

0.33%

256,556

Trexquant Investment LP

$26,262,280

0.33%

255,271

USS Investment Management Ltd

$24,817,125

0.31%

241,224

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
USS Investment Management Ltd	241,224	$24,817,125	100.0%	Sole

JPMORGAN CHASE & CO

$21,115,911

0.27%

205,248

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
J.P. Morgan Trust Co of Delaware	277	$28,497	0.1%	Other
JPMorgan Chase Bank, N.A.	30,838	$3,172,613	15.0%	Defined
J.P. Morgan Investment Management Inc.	43,428	$4,467,872	21.2%	Defined
J.P. Morgan Securities LLC	10,602	$1,090,733	5.2%	Defined
J.P. Morgan Securities plc	1,700	$174,896	0.8%	Defined
JPMorgan Asset Management (UK) Ltd	116,429	$11,978,215	56.7%	Defined
55I, LLC	0	$0	0.0%	Other
J.P. Morgan SE	1,974	$203,085	1.0%	Defined

SILVERCREST ASSET MANAGEMENT GROUP LLC

$20,215,508

0.26%

196,496

IQ EQ FUND MANAGEMENT (IRELAND) Ltd

$19,737,013

0.25%

191,845

Bank of New York Mellon Corp

$19,721,884

0.25%

191,698

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNY Mellon Trust of Delaware joint	400	$41,152	0.2%	Defined
Mellon Investments Corporation joint	58,960	$6,065,804	30.8%	Defined
Newton Investment Management Limited	8,360	$860,076	4.4%	Defined
BNY Mellon Securities Corporation	270	$27,777	0.1%	Defined
The Bank of New York Mellon	113,247	$11,650,851	59.1%	Defined
BNY Mellon, NA joint	9,831	$1,011,411	5.1%	Defined
BNY Mellon Advisors, Inc.	628	$64,608	0.3%	Defined
Held directly	2	$205	0.0%	Defined

FIRST TRUST ADVISORS LP

$19,637,631

0.25%

190,879

Freshford Capital Management, LLC

$18,255,951

0.23%

177,449

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FRESHFORD PARTNERS, LP	78,528	$8,078,960	44.3%	Sole
Long Meadow, L.P.	79,945	$8,224,741	45.1%	Sole
Held directly	18,976	$1,952,250	10.7%	Sole

STATE OF MICHIGAN RETIREMENT SYSTEM

$18,251,014

0.23%

177,401

Metavasi Capital LP

$18,107,291

0.23%

176,004

Universal- Beteiligungs- und Servicegesellschaft mbH

$15,809,260

0.20%

153,667

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Universal-Investment-Gesellschaft mbH joint	153,667	$15,809,260	100.0%	Defined

NEUBERGER BERMAN GROUP LLC

$14,983,648

0.19%

145,642

ARMISTICE CAPITAL, LLC

$14,608,960

0.18%

142,000

PEREGRINE CAPITAL MANAGEMENT LLC

$14,297,233

0.18%

138,970

AQR CAPITAL MANAGEMENT LLC

$13,311,744

0.17%

129,391

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RF&L WEALTH MANAGEMENT, LLC	15	$1,543	0.0%	Other
Prism Planning Partners LLC	314	$32,304	0.2%	Other
Compound Planning, Inc.	6	$617	0.0%	Other
Arax Advisory Partners	796	$81,892	0.6%	Other
HALBERT HARGROVE GLOBAL ADVISORS, LLC	807	$83,024	0.6%	Other
Stokes Family Office, LLC	175	$18,004	0.1%	Other
Held directly	127,278	$13,094,360	98.4%	Defined

Science & Technology Partners, L.P.

$13,294,976

0.17%

129,228

Legal & General Group Plc

$12,549,301

0.16%

121,980

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Legal & General Investment Management America Inc	6,029	$620,263	4.9%	Defined
Legal & General Investment Management Ltd joint	115,951	$11,929,038	95.1%	Defined

PARNASSUS INVESTMENTS, LLC

$12,345,702

0.16%

120,001

PEAK6 LLC

$11,759,184

0.15%

114,300

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PEAK6 Investments LLC joint	114,300	$11,759,184	100.0%	Defined

Swiss National Bank

$11,707,744

0.15%

113,800

OSTERWEIS CAPITAL MANAGEMENT INC

$11,466,799

0.15%

111,458

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSTERWEIS CAPITAL MANAGEMENT LLC/CA	111,458	$11,466,799	100.0%	Sole

Pictet Asset Management Holding SA

$11,138,508

0.14%

108,267

Atika Capital Management LLC

$11,111,039

0.14%

108,000

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Atika Capital Partners LP	62,903	$6,471,460	58.2%	Defined
Optika Master Portfolio Ltd	26,808	$2,758,007	24.8%	Other
Held directly	18,289	$1,881,572	16.9%	Sole

Soleus Capital Management, L.P.

$10,764,231

0.14%

104,629

TD Asset Management Inc

$10,698,079

0.14%

103,986

MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.

$10,299,110

0.13%

100,108

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Global X Management CO LLC joint	95,376	$9,812,282	95.3%	Defined
Global X Management (AUS) Ltd joint	4,732	$486,828	4.7%	Defined

RHUMBLINE ADVISERS

$10,225,037

0.13%

99,388

Mawer Investment Management Ltd.

$10,210,942

0.13%

99,251

Russell Investments Group, Ltd.

$10,042,732

0.13%

97,616

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Russell Investment Management, LLC	55,781	$5,738,749	57.1%	Defined
Russell Investments Capital, LLC	17,767	$1,827,868	18.2%	Defined
Russell Investments France SAS	6,099	$627,465	6.2%	Defined
Russell Investments Trust Company joint	17,969	$1,848,650	18.4%	Other

TWO SIGMA INVESTMENTS, LP

$9,732,448

0.12%

94,600

DEUTSCHE BANK AG\

$9,264,652

0.12%

90,053

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DWS Investment GmbH	15,700	$1,615,216	17.4%	Defined
DWS INVESTMENT MANAGEMENT AMERICAS, INC	2,864	$294,648	3.2%	Defined
DWS Investments UK Ltd	69,524	$7,152,629	77.2%	Defined
DWS International GmbH	1,965	$202,159	2.2%	Defined

NOMURA ASSET MANAGEMENT INTERNATIONAL INC.

$9,184,406

0.12%

89,273

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
NOMURA HOLDINGS INC joint	89,273	$9,184,406	100.0%	Defined

HRT FINANCIAL LP

$9,057,863

0.11%

88,043

ODDO BHF ASSET MANAGEMENT SAS

$9,054,057

0.11%

88,006

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$8,991,712

0.11%

87,400

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	87,400	$8,991,712	100.0%	Other

JANE STREET GROUP, LLC

$8,876,897

0.11%

86,284

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	35,378	$3,639,688	41.0%	Defined
Jane Street Global Trading, LLC	50,906	$5,237,209	59.0%	Defined

Vestmark Advisory Solutions, Inc.

$8,759,408

0.11%

85,142

MANUFACTURERS LIFE INSURANCE COMPANY, THE

$8,214,762

0.10%

79,848

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MANULIFE FINANCIAL CORP joint	79,848	$8,214,762	100.0%	Defined

JANE STREET GROUP, LLC

$8,034,928

0.10%

78,100

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	78,100	$8,034,928	100.0%	Defined

CITIGROUP INC

$7,986,161

0.10%

77,626

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citibank, N.A. joint	22	$2,263	0.0%	Defined
Citigroup Financial Products Inc. joint	77,604	$7,983,898	100.0%	Defined

WELLS FARGO & COMPANY/MN

$7,956,325

0.10%

77,336

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
WELLS FARGO BANK N A	58,634	$6,032,265	75.8%	Defined
WELLS FARGO ADVISORS FINANCIAL NETWORK, LLC	7,310	$752,052	9.5%	Defined
WELLS FARGO CLEARING SERVICES, LLC	11,365	$1,169,231	14.7%	Defined
WELLS FARGO INVESTMENT INSTITUTE, INC.	27	$2,777	0.0%	Defined

CITADEL ADVISORS LLC

$7,839,456

0.10%

76,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	76,200	$7,839,456	100.0%	Defined

ALLIANCEBERNSTEIN L.P.

$7,720,835

0.10%

75,047

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Equitable Holdings, Inc.	75,047	$7,720,835	100.0%	Defined

Ensign Peak Advisors, Inc

$7,645,424

0.10%

74,314

SUSQUEHANNA INTERNATIONAL GROUP, LLP

$7,427,936

0.09%

72,200

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	72,200	$7,427,936	100.0%	Other

ENVESTNET ASSET MANAGEMENT INC

$6,854,585

0.09%

66,627

LPL Financial LLC

$6,573,723

0.08%

63,897

Informed Momentum Co LLC

$6,436,584

0.08%

62,564

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
AHL Partners LLP	58,295	$5,997,389	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
FIDUCIARY TRUST CO INTERNATIONAL	67	$6,892	0.1%	Defined
FIDUCIARY TRUST INTERNATIONAL LLC	525	$54,012	1.0%	Defined
FRANKLIN ADVISERS INC	50,844	$5,230,830	98.8%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	25,580	$2,631,670	50.6%	Defined
JANUS HENDERSON INVESTORS US LLC	24,959	$2,567,781	49.4%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Robert W. Baird & Co. Inc	49,862	$5,129,802	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CREATIVE PLANNING TRUST Co LLC	661	$68,003	1.4%	Defined
Held directly	46,146	$4,747,500	98.6%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Squarepoint Capital LLP	39,981	$4,113,245	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BARCLAYS BANK PLC	38,184	$3,928,369	95.6%	Defined
BARCLAYS CAPITAL INC.	1,760	$181,068	4.4%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
METLIFE INC	36,123	$3,716,334	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Quadrature US Inc.	33,930	$3,490,718	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SUSQUEHANNA SECURITIES, LLC	32,880	$3,382,694	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RBC CMA LTD.	1,886	$194,031	5.7%	Defined
RBC Capital Markets, LLC	15,055	$1,548,858	45.8%	Defined
RBC Dominion Securities Inc.	8,657	$890,632	26.3%	Defined
RBC Private Counsel (USA) Inc.	4,728	$486,416	14.4%	Defined
RBC Rochdale, LLC	2,546	$261,932	7.7%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MITSUBISHI UFJ FINANCIAL GROUP INC	27,485	$2,827,656	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Citadel Securities GP LLC	25,800	$2,654,304	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
OSAIC WEALTH, INC.	23,220	$2,388,873	97.4%	Defined
Osaic Advisory Services, LLC	632	$65,020	2.6%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
CIBC Private Wealth Advisors, Inc.	19,027	$1,957,497	84.7%	Defined
CIBC National Trust Co	2	$205	0.0%	Defined
CIBC WORLD MARKETS CORP	3,429	$352,775	15.3%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BENJAMIN F. EDWARDS & COMPANY, INC.	21,708	$2,233,319	99.5%	Defined
Benjamin F. Edwards Wealth Management, LLC	114	$11,728	0.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
MOODY BANCSHARES INC	20,316	$2,090,110	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Arrowpoint Investment Partners (Hong Kong) Ltd	20,287	$2,087,126	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
RAYMOND JAMES & ASSOCIATES	2,774	$285,389	14.0%	Defined
Raymond James Financial Services Advisors, Inc.	2,799	$287,961	14.1%	Defined
ClariVest Asset Management LLC joint	14,249	$1,465,937	71.9%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 1	18,849	$1,939,185	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Mellon Capital	18,318	$1,884,555	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
XTX EXECUTION SERVICES LLC joint	17,467	$1,797,004	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PGIM Quantitative Solutions LLC	15,015	$1,544,743	88.8%	Defined
Prudential Trust Co	1,900	$195,472	11.2%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jane Street Capital, LLC	16,700	$1,718,096	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SECURITY INVESTORS LLC	14,985	$1,541,656	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
STIFEL NICOLAUS & CO INC \MO\	6,409	$659,357	54.0%	Defined
1919 Investment Counsel, LLC	5,400	$555,552	45.5%	Defined
Held directly	52	$5,349	0.4%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Acadian Inc	11,011	$1,132,811	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ROCKEFELLER & CO. LLC	192	$19,752	1.8%	Defined
ROCKEFELLER TRUST COMPANY, N.A.	262	$26,954	2.4%	Defined
ROCKEFELLER FINANCIAL LLC	10,375	$1,067,380	95.8%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
US BANK NATIONAL ASSOCIATION	2,751	$283,022	27.5%	Defined
U.S. BANCORP ASSET MANAGEMENT INC	7,240	$744,851	72.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manager 2	6,523	$671,086	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BT Funds Management (NZ) Ltd	6,100	$627,568	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PARNASSUS INVESTMENTS, LLC	6,035	$620,880	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
EATON VANCE MANAGEMENT	5,636	$579,831	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Blue Trust, Inc.	3,939	$405,244	94.4%	Defined
Held directly	232	$23,868	5.6%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
DNB FUND	4,132	$425,100	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Nykredit Bank A/S	2,746	$282,508	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Tower Research Capital Investments LLC	296	$30,452	11.2%	Other
Latour Trading LLC (Latour)	2,354	$242,179	88.8%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
ALLSTATE INVESTMENTS LLC	2,623	$269,854	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Amundi Asset Management	2,450	$252,056	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Manufacturers & Traders Trust Company	71	$7,304	3.0%	Defined
Wilmington Trust Investment Advisors, Inc. joint	16	$1,646	0.7%	Defined
Wilmington Trust National Association joint	2,188	$225,100	91.9%	Defined
Wilmington Trust Company	106	$10,905	4.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Brown Advisory LLC	2,348	$241,562	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
National Bank Financial Inc.	2,347	$241,459	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Jump Trading Holdings, LLC joint	2,317	$238,372	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
KBC Bank NV joint	2,121	$218,208	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Strive Asset Management, LLC	2,081	$214,093	100.0%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Edward D. Jones & Co., L.P.	1,910	$196,500	100.0%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
PNC Bank, National Association	1,457	$149,894	92.5%	Defined
PNC Wealth Management LLC	118	$12,139	7.5%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Fifth Third Bank, National Association	1,383	$142,283	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BNP PARIBAS ASSET MANAGEMENT Europe	893	$91,871	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Optiver VOF	329	$33,847	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BESSEMER TRUST Co NATIONAL ASSOCIATION	130	$13,374	61.9%	Defined
Bessemer Trust CO of Delaware, N.A.	80	$8,230	38.1%	Other

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
BMSS Wesson Wealth Solutions, LLC	37	$3,806	23.7%	Sole
Held directly	119	$12,241	76.3%	Sole

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Caisse Federale de Credit Mutuel	100	$10,288	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
TORONTO DOMINION BANK	19	$1,954	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
abrdn Inc.	73,619	$3,498,374	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
JANUS HENDERSON INVESTORS UK Ltd	25,580	$1,215,561	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
Marex Financial	9,500	$451,440	100.0%	Defined

This filing is a combination report: the position is filed across the managers below.

Manager	Shares	Value (USD)	% of position	Discretion
SEI INVESTMENTS MANAGEMENT CORP	35	$1,663	94.6%	Sole
Held directly	2	$95	5.4%	Sole

Key facts CIK 1581280 CUSIP 90184D100 13F (30d) 344 filings 311 filers Visit website Investor relations