LABU · Direxion Daily S&P Biotech Bull 3X Shares ETF
Direxion Shares ETF Trust
$303.55
-0.76%
At close · Sep 4
Net assets $518,889,565
Holdings145
1 month
+9.49%
Year to date
+90.44%
52-week range
$74.95–$341.93
30-session avg volume
397,344
Market performance
Adjusted close · up to five years
Fund profile
- Structure
- Exchange-traded product
- SEC series
- S000049373
- Report date
- Apr 30, 2026
- Holdings coverage
- Tracked U.S. equities
Portfolio concentration
Top 10 holdings—
Calculated only when the SEC filing is stored with complete portfolio coverage.
Portfolio holdings
Latest linked SEC Form NPORT-P report.
| Holding | Ticker / CUSIP | Value | Weight |
|---|---|---|---|
| Apellis Pharmaceuticals Inc | 03753U106 | $7,954,538 | 1.53% |
| Revolution Medicines Inc | RVMD | $7,025,562 | 1.35% |
| Travere Therapeutics Inc | TVTX | $6,910,502 | 1.33% |
| ARROWHEAD PHARMACEUTICALS INC | ARWR | $6,139,842 | 1.18% |
| Twist Bioscience Corporation | TWST | $6,055,595 | 1.17% |
| Summit Therapeutics Inc. | SMMT | $5,984,057 | 1.15% |
| Alkermes PLC | ALKS | $5,893,283 | 1.14% |
| TG Therapeutics Inc | TGTX | $5,846,642 | 1.13% |
| Madrigal Pharmaceuticals Inc | MDGL | $5,820,120 | 1.12% |
| Beam Therapeutics Inc. | BEAM | $5,646,051 | 1.09% |
| Apogee Therapeutics Inc. | APGE | $5,388,347 | 1.04% |
| Scholar Rock Holding Corp. | SRRK | $5,240,129 | 1.01% |
| PRAXIS PRECISION MEDICINES INC | PRAX | $5,211,276 | 1.00% |
| EXELIXIS INC | EXEL | $5,169,853 | 1.00% |
| Mirum Pharmaceuticals Inc. | MIRM | $5,149,353 | 0.99% |
| United Therapeutics Corporation | UTHR | $5,093,014 | 0.98% |
| Natera Inc. | NTRA | $5,091,327 | 0.98% |
| Celcuity Inc. | CELC | $5,089,540 | 0.98% |
| CRISPR Therapeutics AG | CRSP | $5,089,280 | 0.98% |
| Krystal Biotech Inc | KRYS | $4,992,644 | 0.96% |
| Protagonist Therapeutics Inc | PTGX | $4,980,269 | 0.96% |
| NEUROCRINE BIOSCIENCES INC | NBIX | $4,934,465 | 0.95% |
| Incyte Corporation. | INCY | $4,886,112 | 0.94% |
| CG Oncology Inc. | CGON | $4,883,366 | 0.94% |
| Cytokinetics Inc | CYTK | $4,880,719 | 0.94% |
| NUVALENT INC | 670703107 | $4,865,686 | 0.94% |
| Ionis Pharmaceuticals, Inc. | IONS | $4,852,746 | 0.94% |
| Bridgebio Pharma Inc | BBIO | $4,835,693 | 0.93% |
| Vaxcyte Inc | PCVX | $4,830,369 | 0.93% |
| Kymera Therapeutics Inc | KYMR | $4,827,962 | 0.93% |
| Biogen Inc | BIIB | $4,823,612 | 0.93% |
| Cogent Biosciences Inc. | COGT | $4,815,688 | 0.93% |
| PTC Therapeutics, Inc. | PTCT | $4,809,756 | 0.93% |
| Insmed Inc | INSM | $4,748,374 | 0.92% |
| ALNYLAM PHARMACEUTICALS INC | ALNY | $4,689,083 | 0.90% |
| Roivant Sciences Ltd | ROIV | $4,682,372 | 0.90% |
| Halozyme Therapeutics Inc | HALO | $4,648,644 | 0.90% |
| Arcutis Biotherapeutics Inc. | ARQT | $4,574,131 | 0.88% |
| Spyre Therapeutics Inc | SYRE | $4,561,552 | 0.88% |
| Soleno Therapeutics Inc | 834203309 | $4,526,621 | 0.87% |
| AbbVie Inc. | ABBV | $4,505,765 | 0.87% |
| Amgen Inc. | AMGN | $4,450,351 | 0.86% |
| REGENERON PHARMACEUTICALS INC | REGN | $4,431,145 | 0.85% |
| ULTRAGENYX PHARMACEUTICAL INC | RARE | $4,396,227 | 0.85% |
| ACADIA PHARMACEUTICALS INC | ACAD | $4,389,918 | 0.85% |
| Rhythm Pharmaceuticals Inc | RYTM | $4,387,745 | 0.85% |
| Gilead Sciences Inc. | GILD | $4,351,084 | 0.84% |
| Biomarin Pharmaceutical Inc. | BMRN | $4,338,946 | 0.84% |
| Viking Therapeutics Inc. | VKTX | $4,232,903 | 0.82% |
| VERTEX PHARMACEUTICALS INC | VRTX | $4,213,967 | 0.81% |