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INSM · INSMED Inc

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$121.16 +3.09 (+2.62%) At close · Nov 13
Market Cap
$26.58B
Shares
219.38M
Volume · Nov 13 1.54M Avg daily vol (3M) 2.77M

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$121.16 Open$118.18 Day$116.97–121.54 52W close$91.88–211.41 Avg vol 30d3.6M Short int14.1M · 6.4% of shares · 3.6d Short vol50% Last earningsOct 29, 2026 DataJan 2020–Nov 2026 Filing10-Q · Oct 29

Up next

Jan 1, 2027 Est · unconfirmed · in 7 wks

Latest documents

2026
Oct 29
Earnings call
Q3 2026 earnings call

INSMED reported Brinsupri revenue of $400.1 million and Aircase revenue of $124.4 million for third-quarter 2026, raised full-year guidance and expects cash flow positivity in 2027. Aircase received FDA priority review with a January 28th, 2027 PDUFA target date.

Oct 29
Current report 8-K
Total revenue reached $524.4 Million in third quarter

Insmed reported third-quarter total revenue of $524.4 Million, including $400.1 Million from BRINSUPRI and $124.4 Million from ARIKAYCE. It raised full-year 2026 guidance to $1.35 Billion to $1.4 Billion for BRINSUPRI and $460 Million to $470 Million for ARIKAYCE.

Financial results Read from the first part of this long document
5 source passages
—Total Company Revenues of $524.4 Million for the Third Quarter of 2026— —BRINSUPRI^®^ (brensocatib) Revenues of $400.1 Million for the Third Quarter of 2026, Reflecting 29% Growth Over the Second Quarter of 2026— —ARIKAYCE^®^ (amikacin liposome inhalation suspension) Revenues of $124.4 Million for the Third Quarter of 2026, Reflecting 9% Growth Over the Third Quarter of 2025— —Company Raises 2026 BRINSUPRI Revenue Guidance to $1.35 Billion to $1.4 Billion— —Company Raises 2026 ARIKAYCE Revenue Guidance to $460 Million to $470 Million— Open the document at this passage
Oct 29
Quarterly report 10-Q FY2026 Q3, ended Sep 30
Quarterly report for FY2026 Q3

INSMED Inc reported nine-month 2026 product revenues of $1,255.9 million, up 267% from $342.6 million, driven by BRINSUPRI’s $885.8 million U.S. sales growth. R&D rose 34% to $689.5 million and SG&A rose 53% to $747.8 million.

Revenue $524.43M ▲ 268.4% Net loss $100.32M Diluted EPS -$0.46
Read from the MD&A section
Oct 5
Current report 8-K
Director or officer change, or executive pay, Regulation FD disclosure

Insmed Incorporated announced Sara Bonstein will step down as CFO effective October 30, 2026, and a successor search is underway. It reaffirmed full-year 2026 revenue guidance of $1.25 billion to $1.40 billion for BRINSUPRI and $450 million to $470 million for ARIKAYCE.

All documents

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$1.52B
Trailing 12 months
Net income (TTM)
−$605.61M
Trailing 12 months
Revenue growth YoY
+268.4%
Year over year
Operating margin
-37.1%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
-2.4%
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$591.53M
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
+3.3%
Year over year · more shares
Price change (1Y)
-36.6%
Trailing year
Short interest
6.4%
Latest settlement · 3.6 days to cover
View all 125 metrics

Equibles Rating

blended score · not investment advice
Overall
Sell
SellHoldBuy
Technical Buy Momentum Strong Sentiment Neutral Fundamentals Poor Quant / Vol Very High
Market backdrop VIX 19.3 · elevated Equity put/call 0.63
Technical
price trend
Buy
50 / 200-day cross No cross
Price vs 200-day avg −2%
below
Price vs 50-day avg +9%
above
RSI (14) 65
neutral
MACD trend Positive
52-week position 24%
mid-range
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Strong
1-month return +26%
trailing
6-month return +11%
trailing
YTD return −30%
this year
Relative strength +11%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $111 › 200d $123 — 200d above 50d
Institutional flow Accumulating
599 of 673 funds reported for Sep 30 · net +395.1K sh shares · +102 new
Insider flow Distributing
Net -$3.7M over 90 days · 100% sells
Short interest Rising
6.42% of shares out · ▲ +4.5% MoM · 3.6 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
673 holders — near 3-yr high, broad support
Squeeze score 67
elevated · 0–100
Fundamentals
Poor
EPS growth −15%
Y/Y
Free cash flow $-967.6M
Balance sheet $30.5M
net debt
Quant / Vol
risk profile
Very High
Volatility 63%
annualized · 1-yr
Max drawdown −57%
past year
ATR 4.0%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Latest guidance · from the 8-K filed Oct 29, 2026
full-year 2026
BRINSUPRI revenue guidance Raised $1.35B – $1.4B
Aug 6, 2026 $1.25B – $1.4B changed to Oct 29, 2026 $1.35B – $1.4B
ARIKAYCE revenue guidance Raised $460M – $470M
Aug 6, 2026 $450M – $470M changed to Oct 29, 2026 $460M – $470M
peak revenues
Peak revenues for BRINSUPRI at least $7B
Peak revenues for TPIP at least $6B
Peak revenues for ARIKAYCE at least $1B
pre-clinical research programs
Overall expenditures up to 20%
over next 10+ years
Collective >20% CAGR at least 20%
Collective peak revenue estimate of more than $14B at least $14B
Previous outlook earlier release · from the 8-K filed May 7, 2026

Still-open targets the latest release did not restate under the same label.

BRINSUPRI revenues · full-year 2026 at least $1B
Revenue · Full-Year 2026 at least $1B
Guided vs delivered · last 1 settled
2023 revenue guidance 2023
guided $285M – $300M
$305.21M Beat +4.3%

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Buy
0 · 5 · 2
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
−2% Neutral
Price vs 50-day avg
+9% Bullish
RSI (14)
65 Neutral
MACD trend
Positive Bullish
52-week position
24% Neutral
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Mixed
Trend (MA cross) No cross
50d $111 › 200d $123 — 200d above 50d
Institutional flow Accumulating
599 of 673 funds reported for Sep 30 · net +395.1K sh shares · +102 new
Insider flow Distributing
Net -$3.7M over 90 days · 100% sells
Short interest Rising
6.42% of shares out · ▲ +4.5% MoM · 3.6 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
673 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $92 Now $121 · 24% Range high $211
vs 200-day avg -2% vs 50-day avg +9%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

the company's own KPIs, from written earnings releases and filings
Metric Latest Period YoY
ARIKAYCE external R&D expenses 4.15M Three Months Ended September 30, 2026 filing —
Brensocatib external R&D expenses 17.02M Three Months Ended September 30, 2026 filing —
Other external R&D expenses 60.82M Three Months Ended September 30, 2026 filing —
TPIP external R&D expenses 79.23M Three Months Ended September 30, 2026 filing —
ARIKAYCE growth vs. Q2 2025 8% Q2 2026 —
BRINSUPRI sequential growth 49% Q2 2026 —

Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
INSM
INSMED Inc
this stock
$26.58B -30.4% +66.7% — 6.4%
VRTX
Vertex Pharmaceuticals Inc
$136.56B +18.8% +46.2% 34.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$98.84B +23.8% +20.8% 21.1 2.1%
MRNA
Moderna, Inc.
$90.38B +657.4% +4.3% — 8.2%
CSLLY
Csl Ltd
$66.05B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
729
% held
106.0%
Reported
599 of 673
Top holder
BlackRock, Inc.
Held Float
View
Held by Funds
Fund positions
648
View
Short & Settlement
Short Interest Rising
Shares short
14.1M
Days to cover
3.6d
Change
+602.8K sh
View
Short Volume
Short vol %
50%
As of
Nov 13, 2026
Short Total
View
Fails to Deliver
FTD shares
18
Value
$1.8K
As of
Oct 13, 2026
View
Off-Exchange
Off-exchange %
48.0%
Week of
Oct 5, 2026
Off-exch Lit
View
Smart Money
Insider Trades Net selling
Net (90d)
-$3.7M
Buyers / Sellers
0 / 2
Buyers Sellers
View
Congressional Trades Sell
Member
Josh Gottheimer
Amount
$1.0K–$15.0K
Traded
Jun 10, 2026
View
Financials
Financials
Revenue (FY)
$606.4M
Net income (FY)
$-1.3B
EPS diluted
$-6.42
View
Filings
SEC Filings
Latest
8-K
Filed
Oct 29, 2026
This year
23

Insmed reported third-quarter total revenue of $524.4 Million, including $400.1 Million from BRINSUPRI and $124.4 Million from ARIKAYCE. It raised full-year 2026 guidance to $1.35 Billion to $1.4 Billion for BRINSUPRI and $460 Million to $470 Million for ARIKAYCE.

View
Proposed Sales
Value
$3.1M
Shares
25.0K
Filed
Sep 10, 2026
View
Earnings & Events
Webcasts Upcoming
Next webcast
Nov 16, 2026
Last webcast
Oct 29, 2026
View
Investor Relations
Latest news
Insmed to Present at November and…
Published
Nov 4, 2026
Upcoming events
4
View

Performance

5D 20D 120D MTD YTD
INSM +5.9% +25.9% +11.3% +7.6% -30.4%
SPY +2.6% -1.2% +0.5% -0.2% +10.6%
vs SPY +3.3% +27.0% +10.8% +7.8% -41.0%
Key facts CIK 1104506 CUSIP 457669307 13F (30d) 550 filings 499 filers Visit website Investor relations