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PTCT · Ptc Therapeutics, Inc.

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$63.49 +0.13 (+0.21%) At close · Nov 13
Market Cap
$5.30B
Shares
83.54M
Volume · Nov 13 502.9K Avg daily vol (3M) 1.07M

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$63.49 Open$63.12 Day$62.51–63.74 52W close$59.24–89.55 Avg vol 30d1.1M Short int7.8M · 9.3% of shares · 7.5d Short vol37% Last earningsOct 29, 2026 DataJan 2020–Nov 2026 Filing10-Q · Oct 29

Up next

Feb 18, 2027 Est · unconfirmed · in 14 wks

Latest documents

2026
Nov 3
Current report 8-K
Board authorizes $500 million share repurchase program

PTC Therapeutics, Inc. authorized a share repurchase program under which it may repurchase up to $500 million of outstanding common stock, subject to market conditions. Purchases may occur from time to time at management's discretion.

Regulation FD disclosure, Other events
2 source passages
PTC Therapeutics, Inc., (NASDAQ: PTCT) today announced that its Board of Directors has authorized a share repurchase program under which PTC may repurchase up to $500 million of the Company’s outstanding shares of common stock, subject to market conditions. Under the authorization, share repurchases may be made from time to time at management's discretion through a variety of methods, such as open-market transactions including pre-set trading plans, privately negotiated transactions, accelerated share repurchases, and other transactions in accordance with applicable securities laws. Open the document at this passage
Oct 29
Earnings call
Q3 2026 earnings call

PTC Therapeutics raised 2026 product revenue guidance to $960 to $990 million, expects cash flow breakeven in 2026, and plans ST920’s rolling BLA submission for Q4 2026 with potential approval and launch in 2027.

Read from the first part of this long document
Oct 29
Quarterly report 10-Q FY2026 Q3, ended Sep 30
Quarterly report for FY2026 Q3

Ptc Therapeutics, Inc. acquired assets primarily related to ST-920 from Sangamo Therapeutics, Inc. in September 2026. Net income was $29.0 million for the nine months ended September 30, 2026, and Sephience generated $181.9 million in net sales during the three months ended September 30, 2026.

Revenue $357.81M ▲ 69.6% Net loss $51.69M Diluted EPS -$0.62
Read from the MD&A section
Oct 29
Current report 8-K
Financial results, Regulation FD disclosure

PTC Therapeutics reported Q3 2026 total revenue of $358 million, including $276 million product revenue, and raised 2026 total revenue guidance to $1.29 to $1.32 billion and product revenue guidance to $960 to $990 million. Sephience revenue was $182 million.

Sep 21
Current report 8-K
Regulation FD disclosure, Other events

PTC Therapeutics completed its acquisition of ST-920 from Sangamo Therapeutics, a one-time administered AAV gene therapy candidate for Fabry disease, and expects its rolling BLA submission to FDA for accelerated approval to be completed in Q4 2026.

All documents

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$1.16B
Trailing 12 months
Net income (TTM)
−$105.97M
Trailing 12 months
Revenue growth YoY
+69.6%
Year over year
Operating margin
12.8%
Trailing 12 months
P / E (TTM)
—
Trailing earnings
FCF yield
0.0%
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
$1.64B
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
-4.2%
Year over year · fewer shares
Price change (1Y)
-15.3%
Trailing year
Short interest
9.3%
Latest settlement · 7.5 days to cover
View all 125 metrics

Equibles Rating

blended score · not investment advice
Overall
Buy
SellHoldBuy
Technical Neutral Momentum Weak Sentiment Bullish Fundamentals Excellent Quant / Vol Moderate
Market backdrop VIX 19.3 · elevated Equity put/call 0.63
Technical
price trend
Neutral
50 / 200-day cross No cross
Price vs 200-day avg −10%
below
Price vs 50-day avg −1%
below
RSI (14) 49
neutral
MACD trend Positive
52-week position 14%
near low
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Weak
1-month return +7%
trailing
6-month return −6%
trailing
YTD return −16%
this year
Relative strength −7%
vs S&P · 6-mo
Sentiment
smart money
Bullish
Trend (MA cross) No cross
50d $64 › 200d $70 — 200d above 50d
Institutional flow Accumulating
326 of 386 funds reported for Sep 30 · net +920.0K sh shares · +41 new
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
9.31% of shares out · ▼ -6.3% MoM · 7.5 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
386 holders — near 3-yr high, broad support
Squeeze score 65
elevated · 0–100
Fundamentals
Excellent
Revenue growth +36%
Y/Y
EPS growth +264%
Y/Y
Free cash flow $702.3M
Quant / Vol
risk profile
Moderate
Volatility 43%
annualized · 1-yr
Max drawdown −34%
past year
ATR 3.9%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Beat or met 3 of last 5
Latest guidance · from the 8-K filed Oct 29, 2026
Full-year 2026
Total revenue Raised $1.29B – $1.32B
Jul 30, 2026 $1.18B – $1.28B changed to Oct 29, 2026 $1.29B – $1.32B
prior FY $1.73B midpoint −24.6% Y/Y
Total product revenue $960M – $990M
Full-Year 2026
GAAP R&D and SG&A expense guidance $775M – $815M
Non-GAAP R&D and SG&A expense guidance Maintained $680M – $720M
Feb 19, 2026 $680M – $720M changed to Oct 29, 2026 $680M – $720M
Previous outlook earlier release · from the Earnings Call filed Jul 30, 2026

Still-open targets the latest release did not restate under the same label.

Product revenue · full year 2026 $850M – $950M
Prior guidance period ended · from the Earnings Call filed Dec 2, 2025
Total revenue · 2025 full-year $750M – $800M
Guided vs delivered · last 5 settled
Total revenue 2025 full-year
guided $750M – $800M
$1.73B Beat +123.3%
Total Revenue Guidance 2024
guided $600M – $850M
$806.78M In line
Total revenues full year 2023
guided $940M – $1B
$937.82M Miss −3.3%
Total revenues full year 2022
guided $710M – $750M
$698.8M Miss −4.3%

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Neutral
2 · 4 · 1
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
−10% Bearish
Price vs 50-day avg
−1% Neutral
RSI (14)
49 Neutral
MACD trend
Positive Bullish
52-week position
14% Bearish
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Bullish · 3 of 6
Trend (MA cross) No cross
50d $64 › 200d $70 — 200d above 50d
Institutional flow Accumulating
326 of 386 funds reported for Sep 30 · net +920.0K sh shares · +41 new
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
9.31% of shares out · ▼ -6.3% MoM · 7.5 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
386 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $59 Now $63 · 14% Range high $90
vs 200-day avg -10% vs 50-day avg -1%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

the company's own KPIs, from written earnings releases and filings
Metric Latest Period YoY
active patients worldwide 2,000 as of September 30, 2026 —
Shares issued and outstanding 83,327,286 Q2 2026 —

Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
PTCT
Ptc Therapeutics, Inc.
this stock
$5.30B -16.4% +36.2% — 9.3%
VRTX
Vertex Pharmaceuticals Inc
$136.56B +18.8% +46.2% 34.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$98.84B +23.8% +20.8% 21.1 2.1%
MRNA
Moderna, Inc.
$90.38B +657.4% +4.3% — 8.2%
CSLLY
Csl Ltd
$66.05B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Accumulating
Holders
379
% held
122.5%
Reported
326 of 386
Top holder
BlackRock, Inc.
Held Float
View
Held by Funds
Fund positions
428
View
Short & Settlement
Short Interest Falling
Shares short
7.8M
Days to cover
7.5d
Change
-524.0K sh
View
Short Volume
Short vol %
37%
As of
Nov 13, 2026
Short Total
View
Fails to Deliver
FTD shares
6
Value
$375
As of
Oct 9, 2026
View
Off-Exchange
Off-exchange %
48.1%
Week of
Oct 5, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$1.7B
Net income (FY)
$682.6M
EPS diluted
$7.78
View
Filings
SEC Filings
Latest
8-K
Filed
Nov 3, 2026
This year
28

PTC Therapeutics, Inc. authorized a share repurchase program under which it may repurchase up to $500 million of outstanding common stock, subject to market conditions. Purchases may occur from time to time at management's discretion.

View
Proposed Sales
Value
$12.3K
Shares
192
Filed
Oct 9, 2026
View
Exempt Offerings
Offering
$35.9M
Filed
May 8, 2023
View
Earnings & Events
Webcasts Upcoming
Next webcast
Nov 16, 2026
Last webcast
Oct 29, 2026
View
Investor Relations
Latest news
PTC Therapeutics Board of Directo…
Published
Nov 3, 2026
Upcoming events
2
View

Performance

5D 20D 120D MTD YTD
PTCT -3.0% +7.2% -6.2% +5.9% -16.4%
SPY +2.6% -1.2% +0.5% -0.2% +10.6%
vs SPY -5.6% +8.3% -6.7% +6.1% -27.0%
Key facts CIK 1070081 CUSIP 69366J200 13F (30d) 284 filings 256 filers Visit website Investor relations