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EXEL · Exelixis, Inc.

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$69.00 -0.84 (-1.20%) At close · Nov 13
Market Cap
$16.84B
Shares
244.01M
Volume · Nov 13 1.52M Avg daily vol (3M) 2.41M

Price & Indicators

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20d MA 50d MA 200d MA Earnings Filing Insider Congress Investor day
Close$69.00 Open$69.87 Day$68.70–69.94 52W close$40.74–72.75 Avg vol 30d2.8M Short int25.6M · 10.5% of shares · 11.7d Short vol62% Last earningsOct 29, 2026 DataJan 2020–Nov 2026 Filing10-Q · Oct 29

Up next

Feb 9, 2027 Est · unconfirmed · in 12 wks

Latest documents

2026
Oct 29
Earnings call
Q3 2026 earnings call

Exelixis reported third-quarter 2026 total revenues of approximately $659 million and global Cabo franchise net product revenue of $818 million. ZANSA’s PDUFA action date is March 3rd, 2027, and Stellar 304 top-line results are expected in the first quarter next year.

Oct 29
Quarterly report 10-Q FY2026 Q3, ended Oct 2
FDA delays zanzalintinib action date to March 3, 2027

Exelixis reported third-quarter 2026 net product revenues of $604.9 million, up from $542.9 million, while the FDA extended the zanzalintinib metastatic colorectal cancer NDA review to a March 3, 2027 target action date after a major amendment.

Revenue $658.7M ▲ 10.2% Net income $218.1M ▲ 12.7% Diluted EPS $0.85 ▲ 23.2%
Read from the MD&A section
4 source passages
Exelixis, Inc.’s (Exelixis, we, our or us) current expectations, assumptions, estimates and projections about our business and our industry Net product revenues for the third quarter of 2026 were $604.9 million, as compared to $542.9 million for the third quarter of 2025. In September 2026, we announced that the FDA notified us that it had extended the review period for our NDA for zanzalintinib, in combination with atezolizumab, for the treatment of patients with metastatic colorectal cancer by three months. The updated PDUFA target action date is March 3, 2027. Open the document at this passage
Oct 29
Current report 8-K
Financial results

Exelixis reported third-quarter 2026 total revenues of $658.7 million and GAAP diluted EPS of $0.85, while advancing zanzalintinib trials and awaiting an FDA decision with a March 3, 2027 target action date.

Sep 11
Current report 8-K Events of Sep 10
Other events AI summary on its way
All documents

Metrics snapshot

Useful current figures from the complete screener profile.

Revenue (TTM)
$2.50B
Trailing 12 months
Net income (TTM)
$885.14M
Trailing 12 months
Revenue growth YoY
+10.2%
Year over year
Operating margin
40.2%
Trailing 12 months
P / E (TTM)
20.6
Trailing earnings · reciprocal yield 4.9%
FCF yield
6.9%
TTM · current market cap
Return on invested capital
—
Trailing 12 months
Net cash
—
Latest balance sheet
Dividend yield
—
Trailing 12 months
Shares change YoY
-8.2%
Year over year · fewer shares
Price change (1Y)
+62.9%
Trailing year
Short interest
10.5%
Latest settlement · 11.7 days to cover
View all 125 metrics

AI Brief

Q3 FY26 earnings call · Oct 29, 2026
Q3 FY26

TL;DR. Third-quarter revenue and EPS increased year over year, led by cabozantinib growth, while zanzalintinib continued advancing through pivotal and expansion trials and the company repurchased $402.1 million of stock. Risks included higher operating expenses, a three-month FDA review extension, a non-statistically significant NLM survival trend, collaboration-revenue pressure, and the Azurity settlement permitting potential generic entry beginning in 2030 or 2031.

Bullish
  • + U.S. cabozantinib franchise net product revenue grew approximately 11% year over year to $605 million. new
  • + The Federal Circuit affirmed the validity of three asserted patents against MSN. new
  • + Exelixis repurchased $402.1 million of stock under the May 2026 authorization. new
Bearish
  • − The FDA extended the zanzalintinib CRC NDA review by three months after Exelixis submitted updated safety and efficacy data. new
  • − The final NLM overall-survival analysis showed a non-statistically significant trend favoring zanzalintinib plus atezolizumab. new
  • − The Azurity settlement permits potential U.S. generic cabozantinib entry beginning in 2030 or 2031, subject to approval and other conditions. new

AI-generated from the earnings call and 8-K · may contain errors · not investment advice

Equibles Rating

blended score · not investment advice
Overall
Strong Buy
SellHoldBuy
Technical Buy Momentum Very Strong Sentiment Neutral Fundamentals Excellent Quant / Vol Low
Market backdrop VIX 19.3 · elevated Equity put/call 0.63
Technical
price trend
Buy
50 / 200-day cross No cross
Price vs 200-day avg +32%
above
Price vs 50-day avg +11%
above
RSI (14) 59
neutral
MACD trend Negative
52-week position 88%
near high
Volume (OBV) Confirms
volume backs price
Momentum
relative strength
Very Strong
1-month return +11%
trailing
6-month return +38%
trailing
YTD return +57%
this year
Relative strength +38%
vs S&P · 6-mo
Sentiment
smart money
Neutral
Trend (MA cross) No cross
50d $62 › 200d $52 — 50d above 200d
Institutional flow Distributing
692 of 767 funds reported for Sep 30 · net -1.3M sh shares · +83 new
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
10.49% of shares out · ▼ -6.3% MoM · 11.7 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
767 holders — near 3-yr high, broad support
Squeeze score 72
high risk · 0–100
Fundamentals
Excellent
Revenue growth +136%
Y/Y
EPS growth +58%
Y/Y
Free cash flow $875.8M
Valuation P/E 20.6
below peers
Buyback $347.9M
remaining
Quant / Vol
risk profile
Low
Volatility 34%
annualized · 1-yr
Max drawdown −13%
past year
ATR 3.1%
of price · 14-day

Blended from price, momentum, positioning, fundamentals & volatility · daily-close · not investment advice. Market backdrop is context, not part of the score.

Guidance & track record

Beat or met 5 of last 5
Latest guidance · from the 8-K filed Oct 29, 2026
Total revenues · fiscal year 2026 Maintained $2.5B – $2.55B
Aug 5, 2026 $2.5B – $2.55B changed to Oct 29, 2026 $2.5B – $2.55B
prior FY $2.32B midpoint +8.8% Y/Y
Net product revenues · fiscal year 2026 Maintained $2.3B – $2.35B
Aug 5, 2026 $2.3B – $2.35B changed to Oct 29, 2026 $2.3B – $2.35B
Cost of goods sold, % of net product revenues · fiscal year 2026 Maintained 4%
May 5, 2026 3.5% – 4.5% changed to Oct 29, 2026 4%
Selling, general and administrative expenses · fiscal year 2026 Maintained $575M – $625M
Aug 5, 2026 $575M – $625M changed to Oct 29, 2026 $575M – $625M
Research and development expenses · fiscal year 2026 Maintained $825M – $875M
Aug 5, 2026 $825M – $875M changed to Oct 29, 2026 $825M – $875M
Effective tax rate · fiscal year 2026 Lowered 16% – 18%
Aug 5, 2026 21% – 23% changed to Oct 29, 2026 16% – 18%
Guided vs delivered · last 5 settled
Total revenues fiscal year 2024
guided $1.98B – $2.08B
$2.17B Beat +7.1%
Total revenues fiscal year 2023
guided $1.83B – $1.85B
$1.83B In line
Total revenues fiscal year 2022
guided $1.58B – $1.6B
$1.61B Beat +1.5%
Total revenues fiscal year 2021
guided $1.3B – $1.35B
$1.43B Beat +8.3%

Guidance from company 8-Ks · delivered figures from as-reported statements · no analyst estimates involved.

Technicals

trend & momentum for long-term holders Buy
1 · 3 · 3
50 / 200-day cross
No cross Neutral
Price vs 200-day avg
+32% Bullish
Price vs 50-day avg
+11% Bullish
RSI (14)
59 Neutral
MACD trend
Negative Bearish
52-week position
88% Bullish
Volume (OBV)
Confirms Neutral
Market signals — smart money & positioning
Bullish · 2 of 6
Trend (MA cross) No cross
50d $62 › 200d $52 — 50d above 200d
Institutional flow Distributing
692 of 767 funds reported for Sep 30 · net -1.3M sh shares · +83 new
Insider flow Flat
No net insider activity over 90 days
Short interest Falling
10.49% of shares out · ▼ -6.3% MoM · 11.7 days cover
Volume signal Normal
Volume near normal
Institution breadth Multi-yr high
767 holders — near 3-yr high, broad support
Price context
position in its 52-week range
Range low $41 Now $69 · 88% Range high $73
vs 200-day avg +32% vs 50-day avg +11%

Illustrative technical + ownership context — a signal mix, not investment advice.

Key metrics

the company's own KPIs, from written earnings releases and filings
Metric Latest Period YoY
Average net selling price increase of CABOMETYX 4% Three Months Ended June 30, 2026 filing —
Gross margin 96% Three Months Ended June 30, 2026 filing —
Ipsen royalties $50.5M the three months ended June 30, 2026 filing —
Takeda royalty revenues $2.7M the three months ended June 30, 2026 filing —

Figures exactly as the company stated them in writing · click a metric with a to chart its history · period links open the stating document · "filing" marks figures stated in the 10-K/10-Q · YoY needs an exactly comparable prior-year period

Versus peers

Biotechnology — same industry group
Open screener →
Company Mkt cap YTD Rev growth Y/Y P/E Short % shares
EXEL
Exelixis, Inc.
this stock
$16.84B +57.4% +136.3% 20.6 10.5%
VRTX
Vertex Pharmaceuticals Inc
$136.56B +18.8% +46.2% 34.7 1.9%
REGN
Regeneron Pharmaceuticals, Inc.
$98.84B +23.8% +20.8% 21.1 2.1%
MRNA
Moderna, Inc.
$90.38B +657.4% +4.3% — 8.2%
CSLLY
Csl Ltd
$66.05B — — — 0.0%

Peers by industry group · P/E from as-reported trailing EPS · short % is of shares outstanding

At a glance

key data from every section
Ownership
Institutional Holders Reducing
Holders
801
% held
106.3%
Reported
692 of 767
Top holder
BlackRock, Inc.
Held Float
View
Held by Funds
Fund positions
639
View
Short & Settlement
Short Interest Falling
Shares short
25.6M
Days to cover
11.7d
Change
-1.7M sh
View
Short Volume
Short vol %
62%
As of
Nov 13, 2026
Short Total
View
Fails to Deliver
FTD shares
434
Value
$25.6K
As of
Oct 9, 2026
View
Off-Exchange
Off-exchange %
41.8%
Week of
Oct 5, 2026
Off-exch Lit
View
Financials
Financials
Revenue (FY)
$2.3B
Net income (FY)
$782.6M
EPS diluted
$2.78
View
Buybacks
Authorized
$750.0M
Remaining
$347.9M
Spent Remaining
View
Filings
SEC Filings
Latest
10-Q
Filed
Oct 29, 2026
This year
23

Exelixis reported third-quarter 2026 net product revenues of $604.9 million, up from $542.9 million, while the FDA extended the zanzalintinib metastatic colorectal cancer NDA review to a March 3, 2027 target action date after a major amendment.

View
Proposed Sales
Value
$526.5K
Shares
9.8K
Filed
Aug 10, 2026
View
Earnings & Events
Webcasts Upcoming
Next webcast
Nov 17, 2026
Last webcast
Nov 11, 2026
View
Investor Relations
Latest news
Exelixis to Webcast Fireside Chat…
Published
Nov 3, 2026
Upcoming events
2
View

Performance

5D 20D 120D MTD YTD
EXEL -0.8% +10.9% +38.1% -0.6% +57.4%
SPY +2.6% -1.2% +0.5% -0.2% +10.6%
vs SPY -3.4% +12.0% +37.6% -0.4% +46.8%

Capital returns

Buyback program · as of Oct 2, 2026
Authorized
$750.00M
Spent (derived)
$402.10M
Remaining
$347.90M
Spent Remaining

Dividends per share over the trailing 365 days by ex-date · buyback figures as last reported in SEC filings ("spent" derived as authorized − remaining; when several programs run concurrently, authorized is their combined total per the newest filing) · components shown separately — trailing-year buyback spend isn't tracked, so no combined shareholder yield is derived.

Key facts CIK 939767 CUSIP 30161Q104 13F (30d) 616 filings 567 filers Visit website Investor relations