Foresite Capital Management VI LLC
CIK
2013341
Location
WEST HOLLYWOOD, CA
Portfolio Value
Small
$460,271,341
Diversification
Moderately concentrated
Filing Date
Global Rank
#2,445
/ 8,232
▲ 1042
Top Industry
Biotechnology
98.2%
3Y Alpha vs SPY
+46.9%
Period ended 2 months ago
Filed May 15, 2026 · 29d
6 quarters · since Dec 2024
Clone Performance
Feb 2025–Jun 2026 · vs SPYHypothetical growth of cloning every reported 13F position and rebalancing on each filing, indexed to the same start.
Cloned portfolio
+92.8%
SPY
+23.4%
Annualised alpha
+46.9%
Max drawdown
−26.9%
Estimate. 13F holdings are quarter-lagged and long-only, so the clone rebalances about 45 days after each period end — when the filing becomes public — and excludes options and short positions. Past performance does not predict future results.
Portfolio Concentration
17 positions · as of Mar 31, 2026 · Δ vs Dec 31, 2025Top Position
32.7%
−1.9 pts
Top 5
75.6%
−2.6 pts
Top 10
90.5%
−9.5 pts
HHI
1,739
Moderately concentrated−85
Portfolio Trend
6 quarters · across all stocks
Sector Breakdown
As of Mar 31, 2026| Sector | % Portfolio | Value |
|---|---|---|
| Healthcare | 100.0% | $460,271,341 |
Last Quarter's Activity
Export CSVAdded To
Positions the filer increased
4 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| CRVS | Corvus Pharmaceuticals, Inc. | +450,000 | 1,831,233 | $26,790,938 | |
| DNLI | Denali Therapeutics Inc. | +209,971 | 1,209,971 | $23,231,443 | |
| HNGE | Hinge Health, Inc. | +85,400 | 220,400 | $8,498,624 | |
| VSTM | Verastem, Inc. | +11,511 | 3,146,631 | $16,677,144 | |
| No positions match the current search. | |||||
Trimmed
Positions the filer reduced
1 positions
| Ticker | Company | Δ Shares | Shares | Value | Open |
|---|---|---|---|---|---|
| AGIO | Agios Pharmaceuticals, Inc. | −5,000 | 525,000 | $17,760,750 | |
| No positions match the current search. | |||||
New Positions
Positions the filer opened this quarter
8 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| NERV | Minerva Neurosciences, Inc. | 1,986,600 | $11,969,265 | |
| CLDX | Celldex Therapeutics, Inc. | 315,913 | $10,020,760 | |
| ATAI | AtaiBeckley Inc. | 2,750,000 | $9,735,000 | |
| CRNX | Crinetics Pharmaceuticals, Inc. | 212,010 | $7,700,203 | |
| OKUR | OnKure Therapeutics, Inc. | 1,445,783 | $5,985,541 | |
| JBIO | Jade Biosciences, Inc. | 320,000 | $4,496,000 | |
| GHRS | GH Research PLC | 315,492 | $4,435,817 | |
| ZURA | Zura Bio Ltd | 450,000 | $2,677,500 | |
| No positions match the current search. | ||||
Sold Out
Positions the filer fully exited
1 positions
| Ticker | Company | Shares | Value | Open |
|---|---|---|---|---|
| NTRA | Natera, Inc. | 67,356 | $15,430,586 | |
| No positions match the current search. | ||||
17 positions ·
$460,271,341 total
· as of Mar 31, 2026
| Ticker | Company | Type | Shares | Value (USD) | % of Portfolio | History |
|---|---|---|---|---|---|---|
| CGON |
CG Oncology, Inc.
Healthcare
|
Held | 2,221,474 | $150,349,360 | 32.67% | |
| ALMS |
Alumis Inc.
Healthcare
|
Held | 4,247,670 | $93,576,170 | 20.33% | |
| CNTA |
Centessa Pharmaceuticals plc
Healthcare
|
Held | 1,364,019 | $54,178,834 | 11.77% | |
| CRVS |
Corvus Pharmaceuticals, Inc.
Healthcare
|
Added | 1,831,233 | $26,790,938 | 5.82% | |
| DNLI |
Denali Therapeutics Inc.
Healthcare
|
Added | 1,209,971 | $23,231,443 | 5.05% | |
| AGIO |
Agios Pharmaceuticals, Inc.
Healthcare
|
Reduced | 525,000 | $17,760,750 | 3.86% | |
| VSTM |
Verastem, Inc.
Healthcare
|
Added | 3,146,631 | $16,677,144 | 3.62% | |
| KYMR |
Kymera Therapeutics, Inc.
Healthcare
|
Held | 146,332 | $12,187,992 | 2.65% | |
| NERV |
Minerva Neurosciences, Inc.
Healthcare
|
NEW | 1,986,600 | $11,969,265 | 2.60% | |
| CLDX |
Celldex Therapeutics, Inc.
Healthcare
|
NEW | 315,913 | $10,020,760 | 2.18% | |
| ATAI |
AtaiBeckley Inc.
Healthcare
|
NEW | 2,750,000 | $9,735,000 | 2.12% | |
| HNGE |
Hinge Health, Inc.
Healthcare
|
Added | 220,400 | $8,498,624 | 1.85% | |
| CRNX |
Crinetics Pharmaceuticals, Inc.
Healthcare
|
NEW | 212,010 | $7,700,203 | 1.67% | |
| OKUR |
OnKure Therapeutics, Inc.
Healthcare
|
NEW | 1,445,783 | $5,985,541 | 1.30% | |
| JBIO |
Jade Biosciences, Inc.
Healthcare
|
NEW | 320,000 | $4,496,000 | 0.98% | |
| GHRS |
GH Research PLC
Healthcare
|
NEW | 315,492 | $4,435,817 | 0.96% | |
| ZURA |
Zura Bio Ltd
Healthcare
|
NEW | 450,000 | $2,677,500 | 0.58% |